Correction: Human umbilical cord-derived mesenchymal stromal cell exosomes ameliorate aging-associated skeletal muscle atrophy and dysfunction in SAMP10 mice.
Zhe Huang; Limei Piao; Xiangkun Meng; Aiko Inoue; Kazuhiro Hitomi; Hiroyuki Umegaki; Masafumi Kuzuya; Xian Wu Cheng
Stem cell research & therapy, 2025年12月

Human umbilical cord-derived mesenchymal stromal cell exosomes ameliorate aging-associated skeletal muscle atrophy and dysfunction in SAMP10 mice.
Zhe Huang; Limei Piao; Xiangkun Meng; Aiko Inoue; Kazuhiro Hitomi; Hiroyuki Umegaki; Masafumi Kuzuya; Xian Wu Cheng
Stem cell research & therapy, 2025年07月

Cathepsin K deficiency prevented stress-related thrombosis in a mouse FeCl3 model.
Xueying Jin; Xueling Yue; Zhe Huang; Xiangkun Meng; Shengnan Xu; Yuna Wu; Ying Wan; Aiko Inoue; Megumi Narisawa; Lina Hu; Guo-Ping Shi; Hiroyuki Umegaki; Toyoaki Murohara; Yanna Lei; Masafumi Kuzuya; Xian Wu Cheng
Cellular and molecular life sciences : CMLS, 2024年05月

CSF 14-3-3β is associated with progressive cognitive decline in Alzheimer’s disease
Qiang Qiang; Loren Skudder-Hill; Tomoko Toyota; Zhe Huang; Wenshi Wei; Hiroaki Adachi
Brain Communications, 2023年11月

Cathepsin S activity controls chronic stress-induced muscle atrophy and dysfunction in mice.
Ying Wan; Limei Piao; Shengnan Xu; Xiangkun Meng; Zhe Huang; Aiko Inoue; Hailong Wang; Xueling Yue; Xueying Jin; Yongshan Nan; Guo-Ping Shi; Toyoaki Murohara; Hiroyuki Umegaki; Masafumi Kuzuya; Xian Wu Cheng
Cellular and molecular life sciences : CMLS, 2023年08月

Cathepsin S deficiency improves muscle mass loss and dysfunction via the modulation of protein metabolism in mice under pathological stress conditions.
Ying Wan; Limei Piao; Shengnan Xu; Aiko Inoue; Xiangkun Meng; Yanna Lei; Zhe Huang; Hailong Wang; Xueling Yue; Guo-Ping Shi; Masafumi Kuzuya; Xian Wu Cheng
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023年08月

CTSS Modulates Stress-Related Carotid Artery Thrombosis in a Mouse FeCl3 Model.
Shengnan Xu; Limei Piao; Ying Wan; Zhe Huang; Xiangkun Meng; Aiko Inoue; Hailong Wang; Xueling Yue; Xianglan Jin; Guo-Ping Shi; Masafumi Kuzuya; Xian Wu Cheng
Arteriosclerosis, thrombosis, and vascular biology, 2023年07月

Young bone marrow transplantation prevents aging‐related muscle atrophy in a senescence‐accelerated mouse prone 10 model
Aiko Inoue; Limei Piao; Xueling Yue; Zhe Huang; Lina Hu; Hongxian Wu; Xiangkun Meng; Wenhu Xu; Chenglin Yu; Takeshi Sasaki; Kohji Itakura; Hiroyuki Umegaki; Masafumi Kuzuya; Xian Wu Cheng
Journal of Cachexia, Sarcopenia and Muscle, 2022年09月, 査読あり

Cathepsin K Deficiency Prevented Kidney Damage and Dysfunction in Response to 5/6 Nephrectomy Injury in Mice With or Without Chronic Stress
Xueling Yue; Limei Piao; Hailong Wang; Zhe Huang; Xiangkun Meng; Takeshi Sasaki; Aiko Inoue; Kae Nakamura; Ying Wan; Shengnan Xu; Guo-Ping Shi; Weon Kim; Toyoaki Murohara; Masafumi Kuzuya; Xian Wu Cheng
Hypertension, 2022年08月, 査読あり, 招待無し

Human umbilical cord-derived mesenchymal stromal cells ameliorate aging-associated skeletal muscle atrophy and dysfunction by modulating apoptosis and mitochondrial damage in SAMP10 mice
Limei Piao; Zhe Huang; Aiko Inoue; Masafumi Kuzuya; Xian Wu Cheng
Stem Cell Research & Therapy, 2022年06月, 査読あり
責任著者

Cathepsin K activity controls cachexia‐induced muscle atrophy via the modulation of IRS1 ubiquitination
Xiangkun Meng; Zhe Huang; Aiko Inoue; Hailong Wang; Ying Wan; Xueling Yue; Shengnan Xu; Xueying Jin; Guo‐Ping Shi; Masafumi Kuzuya; Xian Wu Cheng
Journal of Cachexia, Sarcopenia and Muscle, 2022年04月

Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice
Hiroki Goto; Aiko Inoue; Limei Piao; Lina Hu; Zhe Huang; Xiangkun Meng; Yusuke Suzuki; Hiroyuki Umegaki; Masafumi Kuzuya; Xian Wu Cheng
Stem Cells International, 2021年11月, 査読あり, 招待無し

Expanding role for single‐pill combination drug therapy in the initial treatment of hypertension?
Yanglong Li; Megumi Narisawa; Zhe Huang; Xiangkunm Meng; Hailong Wang; Xueying Jin; Xionghu Shen; Xian Wu Cheng
The Journal of Clinical Hypertension, 2021年11月

Deficiency of cysteinyl cathepsin K suppresses the development of experimental intimal hyperplasia in response to chronic stress
Xiangkun Meng; Limei Piao; Hailong Wang; Aiko Inoue; Zhe Huang; Haiying Jiang; Kae Nakamura; Takeshi Sasaki; Xiang Li; Wenhu Xu; Chenglin Yu; Lina Hu; Hongxian Wu; Toyoaki Murohara; Guo-Ping Shi; Masafumi Kuzuya; Xian Wu Cheng
Journal of Hypertension, 2020年08月, 査読あり, 招待無し

PLF‐1 (Proliferin‐1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia
Lina Hu; Zhe Huang; Hideki Ishii; Hongxian Wu; Susumu Suzuki; Aiko Inoue; Weon Kim; Haiying Jiang; Xiang Li; Enbo Zhu; Limei Piao; Guangxian Zhao; Yanna Lei; Kenji Okumura; Guo‐Ping Shi; Toyoaki Murohara; Masafumi Kuzuya; Xian Wu Cheng
Journal of the American Heart Association, 2019年12月, 査読あり
筆頭著者

DRPLAトランスジェニックマウスの病態生理学的分析と治療的介入(Pathophysiological analysis and therapeutic intervention of DRPLA transgenic mice)
Toyota Tomoko; 黄 哲; 佐藤 俊哉; 辻 省次; 足立 弘明
てんかん研究, 2019年09月

Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice
Aiko Inoue; Xian Wu Cheng; Zhe Huang; Lina Hu; Ryosuke Kikuchi; Haiying Jiang; Limei Piao; Takeshi Sasaki; Kohji Itakura; Hongxian Wu; Guangxian Zhao; Yanna Lei; Guang Yang; Enbo Zhu; Xiang Li; Kohji Sato; Teruhiko Koike; Masafumi Kuzuya
Journal of Cachexia, Sarcopenia and Muscle, 2017年06月, 査読あり

Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K−Akt/p-HDAC6 Signaling Pathway
Hongxian Wu; Xian Wu Cheng; Lina Hu; Kyosuke Takeshita; Chen Hu; Qiuna Du; Xiang Li; Enbo Zhu; Zhe Huang; Maimaiti Yisireyili; Guangxian Zhao; Limei Piao; Aiko Inoue; Haiying Jiang; Yanna Lei; Xiaohong Zhang; Shaowen Liu; Qiuyan Dai; Masafumi Kuzuya; Guo-Ping Shi; Toyoaki Murohara
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016年08月, 査読あり

オートファジー活性化天然化合物による神経変性疾患の治療
Zhe HUANG; Hiroaki ADACHI
Journal of UOEH, 2016年, 査読あり
筆頭著者

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration
Ying Ding; Hiroaki Adachi; Masahisa Katsuno; Zhe Huang; Yue-Mei Jiang; Naohide Kondo; Madoka Iida; Genki Tohnai; Hideaki Nakatsuji; Hiroshi Funakoshi; Toshikazu Nakamura; Gen Sobue
Biochemical and Biophysical Research Communications, 2015年12月, 査読あり

Neuronal intranuclear inclusion disease manifesting with new-onset epilepsy in the elderly
Tomoko Toyota; Zhe Huang; Souhei Nohara; Kazumasa Okada; Shingo Kakeda; Yukunori Korogi; Toshiyuki Nakayama; Jun Sone; Gen Sobue; Hiroaki Adachi
NEUROLOGY AND CLINICAL NEUROSCIENCE, 2015年11月

Cathepsin S activity controls ischemia-induced neovascularization in mice
Xiang Li; Xian Wu Cheng; Lina Hu; Hongxian Wu; Guo-Ping; Chang-Ning Hao; Haiying Jiang; Enbo Zhu; Zhe Huang; Aiko Inoue; Takeshi Sasaki; Qiuna Du; Kyosuke Takeshita; Kenji Okumura; Toyoaki Murohara; Masafumi Kuzuya
International Journal of Cardiology, 2015年03月, 査読あり

Cathepsin K-mediated notch1 activation contributes to neovascularization in response to hypoxia
Haiying Jiang; Xian Wu Cheng; Guo-Ping Shi; Lina Hu; Aiko Inoue; Yumiko Yamamura; Hongxian Wu; Kyosuke Takeshita; Xiang Li; Zhe Huang; Haizhen Song; Masashi Asai; Chang-Ning Hao; Kazumasa Unno; Teruhiro Koike; Yoshiharu Oshida; Kenji Okumura; Toyoaki Murohara; Masafumi Kuzuya
Nature Communications, 2014年09月, 査読あり

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease
Qiang Qiang; Hiroaki Adachi; Zhe Huang; Yue-Mei Jiang; Masahisa Katsuno; Makoto Minamiyama; Hideki Doi; Shinjiro Matsumoto; Naohide Kondo; Yu Miyazaki; Madoka Iida; Genki Tohnai; Gen Sobue
Journal of Neurochemistry, 2013年07月, 査読あり

dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration
Kensuke Ikenaka; Kaori Kawai; Masahisa Katsuno; Zhe Huang; Yue-Mei Jiang; Yohei Iguchi; Kyogo Kobayashi; Tsubasa Kimata; Masahiro Waza; Fumiaki Tanaka; Ikue Mori; Gen Sobue
PLoS ONE, 2013年02月, 査読あり

c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis
Ryu Katsumata; Shinsuke Ishigaki; Masahisa Katsuno; Kaori Kawai; Jun Sone; Zhe Huang; Hiroaki Adachi; Fumiaki Tanaka; Fumihiko Urano; Gen Sobue
PLoS ONE, 2012年09月, 査読あり

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2
Yu Miyazaki; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Yue-Mei Jiang; Zhe Huang; Hideki Doi; Shinjiro Matsumoto; Naohide Kondo; Madoka Iida; Genki Tohnai; Fumiaki Tanaka; Shin-ichi Muramatsu; Gen Sobue
Nature Medicine, 2012年07月, 査読あり

Cysteine Protease Cathepsins in Atherosclerosis-Based Vascular Disease and Its Complications
Xian Wu Cheng; Zhe Huang; Masafumi Kuzuya; Kenji Okumura; Toyoaki Murohara
Hypertension, 2011年12月, 査読あり

Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin
Xian Wu Cheng; Masafumi Kuzuya; Takeshi Sasaki; Aiko Inoue; Lina Hu; Haizhen Song; Zhe Huang; Ping Li; Kyosuke Takeshita; Akihiro Hirashiki; Kohji Sato; Guo-Ping Shi; Kenji Okumura; Toyoaki Murohara
Journal of Hypertension, 2011年03月, 査読あり

Preventive effects of a water-soluble derivative of chroman moiety of vitamin E on lipid hydroperoxide-induced cell injuries and DNA cleavages through repressions of oxidative stress in the cytoplasm of human keratinocytes
Zhe Huang; Yuichiro Senoh; Shinya Katoh; Nobuhiko Miwa
Journal of Cellular Biochemistry, 2004年06月, 査読あり

CTSS Modulates Stress-Related Carotid Artery Thrombosis in a Mouse FeCl3 Model
Xu S, Piao L, Wan Y, Huang Z, Meng X, Inoue A, Wang H, Yue X, Jin X, Shi GP, Kuzuya M, Cheng XW.
Arteriosclerosis, thrombosis, and vascular biology, 2023年07月, 査読あり, 招待無し

Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway.
Wu H, Cheng XW, Hu L, Takeshita K, Hu C, Du Q, Li X, Zhu E, Huang Z, Yisireyili M, Zhao G, Piao L, Inoue A, Jiang H, Lei Y, Zhang X, Liu S, Dai Q, Kuzuya M, Shi GP, Murohara T.
Arteriosclerosis, thrombosis, and vascular biology, 2016年08月, 査読あり, 招待無し

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration.
Ding Ying, Adachi Hiroaki, Katsuno Masahisa, Huang Zhe, Jiang Yue-Mei, Kondo Naohide, Iida Madoka, Tohnai Genki, Nakatsuji Hideaki, Funakoshi Hiroshi, Nakamura Toshikazu, Sobue Gen
Biochemical and biophysical research communications, 2015年12月, 査読あり, 招待無し

Cathepsin K deficiency prevented stress-related thrombosis in a mouse FeCl3 model
Jin X, Yue X, Huang Z, Meng X, Xu S, Wu Y, Wan Y, Inoue A, Narisawa M, Hu L, Shi GP, Umegaki H, Murohara T, Lei Y, Kuzuya M, Cheng XW.
Cellular and molecular life sciences, 2024年05月, 査読あり, 招待無し

Cathepsin S activity controls chronic stress-induced muscle atrophy and dysfunction in mice
Wan Y, Piao L, Xu S, Meng X, Huang Z, Inoue A, Wang H, Yue X, Jin X, Nan Y, Shi GP, Murohara T, Umegaki H, Kuzuya M, Cheng XW.
Cellular and molecular life sciences, 2023年08月, 査読あり, 招待無し

Cathepsin S deficiency improves muscle mass loss and dysfunction via the modulation of protein metabolism in mice under pathological stress conditions
Wan Y, Piao L, Xu S, Inoue A, Meng X, Lei Y, Huang Z, Wang H, Yue X, Shi GP, Kuzuya M, Cheng XW.
FASEB journal, 2023年08月, 査読あり, 招待無し

Cathepsin S activity controls ischemia-induced neovascularization in mice
Li X, Cheng XW, Hu L, Wu H, Guo-Ping, Hao CN, Jiang H, Zhu E, Huang Z, Inoue A, Sasaki T, Du Q, Takeshita K, Okumura K, Murohara T, Kuzuya M.
International journal of cardiology, 2015年03月, 査読あり, 招待無し

Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation.
Huang Zhe, Adachi Hiroaki
Journal of UOEH, 2016年06月, 査読あり, 招待無し
筆頭著者

Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice.
Inoue A, Cheng XW, Huang Z, Hu L, Kikuchi R, Jiang H, Piao L, Sasaki T, Itakura K, Wu H, Zhao G, Lei Y, Yang G, Zhu E, Li X, Sato K, Koike T, Kuzuya M.
Journal of cachexia, sarcopenia and muscle, 2017年06月, 査読あり, 招待無し

Young bone marrow transplantation prevents aging-related muscle atrophy in a senescence-accelerated mouse prone 10 model.
Inoue A, Piao L, Yue X, Huang Z, Hu L, Wu H, Meng X, Xu W, Yu C, Sasaki T, Itakura K, Umegaki H, Kuzuya M, Cheng XW.
Journal of cachexia, sarcopenia and muscle, 2022年12月, 査読あり, 招待無し

Cathepsin K activity controls cachexia-induced muscle atrophy via the modulation of IRS1 ubiquitination
Meng X, Huang Z, Inoue A, Wang H, Wan Y, Yue X, Xu S, Jin X, Shi GP, Kuzuya M, Cheng XW.
Journal of cachexia, sarcopenia and muscle, 2022年04月, 査読あり, 招待無し

CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer’s disease
Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H.
The Journal of the Neurological Sciences, 2024年02月, 査読あり, 招待無し

CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer's disease.
Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H.
Neurobiology of Aging, 2025年06月, 査読あり, 招待無し

Neuronal intranuclear inclusion disease manifesting with new-onset epilepsy in the elderly
Toyota Tomoko, Huang Zhe, Nohara Souhei, Okada Kazumasa, Kakeda Shingo, Korogi Yukunori, Nakayama Toshiyuki, Sone Jun, Sobue Gen, Adachi Hiroaki
Neurology and Clinical Neuroscience, 2015年11月, 査読あり, 招待無し

Human umbilical cord-derived mesenchymal stromal cells ameliorate aging-associated skeletal muscle atrophy and dysfunction by modulating apoptosis and mitochondrial damage in SAMP10 mice.
Piao L, Huang Z, Inoue A, Kuzuya M, Cheng XW.
Stem cell research & therapy, 2022年06月, 査読あり, 招待無し