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Last Updated :2026/06/12

原田 景太

第2生理学
講師

研究活動情報

■ 論文
  • Expression of Mitochondrial Uncoupling Proteins and GABA Signaling Molecules in Unstimulated and Nerve Growth Factor-Stimulated PC12 Cells: Models for Chromaffin Cells and Sympathetic Neurons.
    Keita Harada; Hidetada Matsuoka; Masumi Inoue
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2025年
  • Developmental Changes in Gap Junction Expression in Rat Adrenal Medullary Chromaffin Cells.
    Tamiji Nakashima; Ke-Yong Wang; Hidetada Matsuoka; Koichi Ogawa; Yutaka Endo; Keita Harada; Masumi Inoue
    Acta histochemica et cytochemica, 2024年12月
  • Enhancement of muscarinic receptor-mediated excitation in spontaneously hypertensive rat adrenal medullary chromaffin cells.
    Masumi Inoue; Keita Harada
    Autonomic neuroscience : basic & clinical, 2023年09月
  • Muscarinic Receptor Stimulation Does Not Inhibit Voltage-dependent Ca2+ Channels in Rat Adrenal Medullary Chromaffin Cells.
    Keita Harada; Masumi Inoue
    Acta histochemica et cytochemica, 2023年08月
  • Expression and function of mitochondrial inhibitor factor-1 and TASK channels in adrenal cells.
    Donghee Kim; Keita Harada; Masumi Inoue
    Biochemical and biophysical research communications, 2023年02月
  • Immunocytochemistry of Acutely Isolated Adrenal Medullary Chromaffin Cells.
    Keita Harada; Hidetada Matsuoka; Masumi Inoue
    Methods in molecular biology (Clifton, N.J.), 2023年
  • Expression of p11 and heteromeric TASK channels in mouse adrenal cortical cells and H295R cells.
    Hidetada Matsuoka; Keita Harada; Akira Sugawara; Donghee Kim; Masumi Inoue
    Acta histochemica, 2022年07月
  • Expression of p11 and TASK1 Channels in Rat Carotid Body Glomus Cells Subjected to Chronic Intermittent Hypoxia.
    Hidetada Matsuoka; Mieczyslaw Pokorski; Kotaro Takeda; Yasumasa Okada; Keita Harada; Masumi Inoue
    Journal of UOEH, 2022年
  • Mechanisms for establishment of GABA signaling in adrenal medullary chromaffin cells.
    Keita Harada; Hidetada Matsuoka; Yumiko Toyohira; Yuchio Yanagawa; Masumi Inoue
    Journal of neurochemistry, 2021年07月
  • Expression of p11 and Heteromeric TASK Channels in Rat Carotid Body Glomus Cells and Nerve Growth Factor-differentiated PC12 Cells.
    Hidetada Matsuoka; Mieczyslaw Pokorski; Keita Harada; Reiji Yoshimura; Masumi Inoue
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2020年10月
  • TASK channels: channelopathies, trafficking, and receptor-mediated inhibition.
    Masumi Inoue; Hidetada Matsuoka; Keita Harada; Go Mugishima; Masaki Kameyama
    Pflugers Archiv : European journal of physiology, 2020年07月
  • Mechanisms for pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea-pig and mouse adrenal medullary cells.
    Masumi Inoue; Keita Harada; Hidetada Matsuoka
    European journal of pharmacology, 2020年04月
  • Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells.
    Hidetada Matsuoka; Keita Harada; Keisuke Mashima; Masumi Inoue
    Cellular signalling, 2020年01月
  • STIM1-dependent membrane insertion of heteromeric TRPC1-TRPC4 channels in response to muscarinic receptor stimulation.
    Keita Harada; Hidetada Matsuoka; Masumi Inoue
    Journal of cell science, 2019年05月
  • Differences among muscarinic agonists in M1 receptor-mediated nonselective cation channel activation and TASK1 channel inhibition in adrenal medullary cells.
    Masumi Inoue; Keita Harada; Minoru Matsui; Hidetada Matsuoka
    European journal of pharmacology, 2019年01月
  • Lack of p11 expression facilitates acidity-sensing function of TASK1 channels in mouse adrenal medullary cells.
    Masumi Inoue; Hidetada Matsuoka; Florian Lesage; Keita Harada
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019年01月
  • Expression and regulation of M-type K+ channel in PC12 cells and rat adrenal medullary cells.
    Keita Harada; Hidetada Matsuoka; Masumi Inoue
    Cell and tissue research, 2018年06月
  • Muscarinic receptors in adrenal chromaffin cells: physiological role and regulation of ion channels.
    Masumi Inoue; Hidetada Matsuoka; Keita Harada; Lung-Sen Kao
    Pflugers Archiv : European journal of physiology, 2018年01月
  • GABA Signaling and Neuroactive Steroids in Adrenal Medullary Chromaffin Cells.
    Keita Harada; Hidetada Matsuoka; Hiroaki Fujihara; Yoichi Ueta; Yuchio Yanagawa; Masumi Inoue
    Frontiers in cellular neuroscience, 2016年
  • Identification of muscarinic receptor subtypes involved in catecholamine secretion in adrenal medullary chromaffin cells by genetic deletion.
    Keita Harada; Hidetada Matsuoka; Hironori Miyata; Minoru Matsui; Masumi Inoue
    British journal of pharmacology, 2015年03月
  • Nerve growth factor-induced endocytosis of TWIK-related acid-sensitive K⁺ 1 channels in adrenal medullary cells and PC12 cells.
    Hidetada Matsuoka; Keita Harada; Jun Nakamura; Masumi Inoue
    Pflugers Archiv : European journal of physiology, 2013年07月
  • Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.
    Masumi Inoue; Keita Harada; Hidetada Matsuoka; Jun Nakamura; Akira Warashina
    American journal of physiology. Cell physiology, 2012年09月
  • Differential distribution of synaptotagmin-1, -4, -7, and -9 in rat adrenal chromaffin cells.
    Hidetada Matsuoka; Keita Harada; Jun Nakamura; Mitsunori Fukuda; Masumi Inoue
    Cell and tissue research, 2011年04月
  • Heterogeneous levels of oxidative phosphorylation enzymes in rat adrenal glands.
    Koichi Ogawa; Keita Harada; Yutaka Endo; Sueko Sagawa; Masumi Inoue
    Acta histochemica, 2011年01月
  • Identification and role of muscarinic receptor subtypes expressed in rat adrenal medullary cells.
    Keita Harada; Hidetada Matsuoka; Takeyoshi Sata; Akira Warashina; Masumi Inoue
    Journal of pharmacological sciences, 2011年
  • Paracrine role of GABA in adrenal chromaffin cells.
    Masumi Inoue; Keita Harada; Hidetada Matsuoka; Akira Warashina
    Cellular and molecular neurobiology, 2010年11月
  • Localization of type-2 angiotensin II receptor in adrenal gland.
    Keita Harada; Hidetada Matsuoka; Naohiro Fujimoto; Yutaka Endo; Yoshitaka Hasegawa; Akira Matsuo; Yuta Kikuchi; Tetsuro Matsumoto; Masumi Inoue
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2010年07月
  • Storage of GABA in chromaffin granules and not in synaptic-like microvesicles in rat adrenal medullary cells.
    Keita Harada; Hidetada Matsuoka; Jun Nakamura; Mitsunori Fukuda; Masumi Inoue
    Journal of neurochemistry, 2010年07月
  • Ca2+ pathway involved in the refilling of store sites in rat adrenal medullary cells.
    Hidetada Matsuoka; Keita Harada; Tomoya Ikeda; Kouta Uetsuki; Takeyoshi Sata; Akira Warashina; Masumi Inoue
    American journal of physiology. Cell physiology, 2009年04月
  • Molecular mechanisms supporting a paracrine role of GABA in rat adrenal medullary cells.
    Hidetada Matsuoka; Keita Harada; Yutaka Endo; Akira Warashina; Yoshiaki Doi; Jun Nakamura; Masumi Inoue
    The Journal of physiology, 2008年10月
  • Inhibition of TASK1-like channels by muscarinic receptor stimulation in rat adrenal medullary cells.
    Masumi Inoue; Keita Harada; Hidetada Matsuoka; Takeyoshi Sata; Akira Warashina
    Journal of neurochemistry, 2008年08月
  • Organelles containing inositol trisphosphate receptor type 2 in adrenal medullary cells
    Yutaka Endo; Keita Harada; Naoji Fujishiro; Hisasachi Funahashi; Seiji Shioda; Glenn D. Prestwich; Katsuhiko Mikoshiba; Masumi Inoue
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2006年12月, 査読あり, 招待無し
  • Subunit composition and role of Na+,K+-ATPases in ventricular myocytes.
    Keita Harada; Hai Lin; Yutaka Endo; Naoji Fujishiro; Yasuji Sakamoto; Masumi Inoue
    The journal of physiological sciences : JPS, 2006年02月
  • A mutation in the N-terminus of troponin I that is associated with hypertrophic cardiomyopathy affects the Ca(2+)-sensitivity, phosphorylation kinetics and proteolytic susceptibility of troponin.
    Aldrin V Gomes; Keita Harada; James D Potter
    Journal of molecular and cellular cardiology, 2005年11月
  • Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in alpha-tropomyosin.
    Audrey N Chang; Keita Harada; Michael J Ackerman; James D Potter
    The Journal of biological chemistry, 2005年10月
  • Role of troponin T in disease.
    Aldrin V Gomes; Junor A Barnes; Keita Harada; James D Potter
    Molecular and cellular biochemistry, 2004年08月
  • Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction.
    Keita Harada; James D Potter
    The Journal of biological chemistry, 2004年04月
  • Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
    Qun-Wei Lu; Sachio Morimoto; Keita Harada; Cheng-Kun Du; Fumi Takahashi-Yanaga; Yoshikazu Miwa; Toshiyuki Sasaguri; Iwao Ohtsuki
    Journal of molecular and cellular cardiology, 2003年12月
  • Different functional properties of troponin T mutants that cause dilated cardiomyopathy.
    Gayathri Venkatraman; Keita Harada; Aldrin V Gomes; W Glenn L Kerrick; James D Potter
    The Journal of biological chemistry, 2003年10月
  • Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.
    S Morimoto; Q-W Lu; K Harada; F Takahashi-Yanaga; R Minakami; M Ohta; T Sasaguri; I Ohtsuki
    Proceedings of the National Academy of Sciences of the United States of America, 2002年01月
  • Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy.
    F Takahashi-Yanaga; S Morimoto; K Harada; R Minakami; F Shiraishi; M Ohta; Q W Lu; T Sasaguri; I Ohtsuki
    Journal of molecular and cellular cardiology, 2001年12月
  • Functional consequences of the deletion mutation deltaGlu160 in human cardiac troponin T.
    K Harada; F Takahashi-Yanaga; R Minakami; S Morimoto; I Ohtsuki
    Journal of biochemistry, 2000年02月
  • Roles of troponin isoforms in pH dependence of contraction in rabbit fast and slow skeletal and cardiac muscles.
    S Morimoto; K Harada; I Ohtsuki
    Journal of biochemistry, 1999年07月
  • TASKチャネルは副腎髄質細胞においてアシドーシスを感知する。
    ◎井上真澄、松岡秀忠、原田景太
    日本生理学雑誌, 2017年02月, 指定なし, 指定なし
    ラスト(シニア)オーサー
  • Expression of p11 and heteromeric TASK channels in mouse adrenal cortical cells and H295R cells.
    Matsuoka Hidetada, Harada Keita, Sugawara Akira, Kim Donghee, Inoue Masumi
    Acta histochemica, 2022年05月, 査読あり, 招待無し
  • Developmental Changes in Gap Junction Expression in Rat Adrenal Medullary Chromaffin Cells.
    Nakashima Tamiji, Wang Ke-Yong, Matsuoka Hidetada, Ogawa Koichi, Endo Yutaka, Harada Keita, Inoue Masumi
    Acta histochemica et cytochemica, 2024年12月, 査読あり, 招待無し
    筆頭著者, 責任著者
  • Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.
    Inoue Masumi, Harada Keita, Matsuoka Hidetada, Nakamura Jun, Warashina Akira
    American journal of physiology. Cell physiology, 2012年09月, 査読あり, 指定なし
  • Ca2+ pathway involved in the refilling of store sites in rat adrenal medullary cells.
    Matsuoka Hidetada, Harada Keita, Ikeda Tomoya, Uetsuki Kouta, Sata Takeyoshi, Warashina Akira, Inoue Masumi
    American journal of physiology. Cell physiology, 2009年04月, 査読あり, 指定なし
  • Enhancement of muscarinic receptor-mediated excitation in spontaneously hypertensive rat adrenal medullary chromaffin cells.
    Inoue Masumi, Harada Keita
    Autonomic neuroscience : basic & clinical, 2023年09月, 査読あり, 招待無し
  • Expression and function of mitochondrial inhibitor factor-1 and TASK channels in adrenal cells.
    Kim Donghee, Harada Keita, Inoue Masumi
    Biochemical and biophysical research communications, 2023年02月, 査読あり, 招待無し
  • Identification of muscarinic receptor subtypes involved in catecholamine secretion in adrenal medullary chromaffin cells by genetic deletion.
    Harada Keita, Matsuoka Hidetada, Miyata Hironori, Matsui Minoru, Inoue Masumi
    British journal of pharmacology, 2015年03月, 査読あり, 指定なし
    筆頭著者
  • Expression and regulation of M-type K+ channel in PC12 cells and rat adrenal medullary cells.
    Harada Keita, Matsuoka Hidetada, Inoue Masumi
    Cell and tissue research, 2018年03月, 指定なし, 指定なし
    筆頭著者
  • Differential distribution of synaptotagmin-1, -4, -7, and -9 in rat adrenal chromaffin cells.
    Matsuoka Hidetada, Harada Keita, Nakamura Jun, Fukuda Mitsunori, Inoue Masumi
    Cell and tissue research, 2011年04月, 査読あり, 指定なし
  • Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells.
    Matsuoka Hidetada, Harada Keita, Mashima K, Inoue Masumi
    Cellular Signaling, 2020年01月, 査読あり, 招待無し
  • Paracrine role of GABA in adrenal chromaffin cells.
    Inoue Masumi, Harada Keita, Matsuoka Hidetada, Warashina Akira
    Cellular and molecular neurobiology, 2010年11月, 査読あり, 指定なし
  • Mechanisms for pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea-pig and mouse adrenal medullary cells.
    Inoue Masumi, Harada Keita, Matsuoka Hidetada
    European Journal of Pharmacology, 2020年01月, 査読あり, 招待無し
  • Differences among muscarinic agonists in M1 receptor-mediated nonselective cation channel activation and TASK1 channel inhibition in adrenal medullary cells.
    Inoue Masumi, Harada Keita, Matsui Minoru, Matsuoka Hidetada
    European journal of pharmacology, 2019年01月, 査読あり, 招待無し
  • Lack of p11 expression facilitates acidity-sensing function of TASK1 channels in mouse adrenal medullary cells.
    Inoue Masumi, Matsuoka Hidetada, Lesage Florian, Harada Keita
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019年01月, 査読あり, 招待無し
    ラスト(シニア)オーサー
  • GABA Signaling and Neuroactive Steroids in Adrenal Medullary Chromaffin Cells.
    Harada Keita, Matsuoka Hidetada, Fujihara Hiroaki, Ueta Yoichi, Yanagawa Yuchio, Inoue Masumi
    Frontiers in cellular neuroscience, 2016年04月, 査読あり, 招待無し
    筆頭著者
  • Prior ensemble learning : Theory and application to MR image priors.
    Kubota Nanako, Kasahara Yufu, Harada Ken, Fujimoto Koji, Okada Tomohisa, Inoue Masato
    International journal of computer assisted radiology and surgery, 2021年11月, 指定なし, 指定なし
  • STIM -dependent membrne insertion of heteromeric TRPC1-TRPC4 channels in response to muscarinic receptor stimulation.
    Harada Keita, Matsuoka Hidetada, Masumi Inoue
    Journal of Cell Science, 2019年05月, 査読あり, 招待無し
    筆頭著者
  • Expression of p11 and TASK1 Channels in Rat Carotid Body Glomus Cells Subjected to Chronic Intermittent Hypoxia.
    Matsuoka Hidetada, Pokorski Mieczyslaw, Takeda Kotaro, Okada Yasumasa, Harada Keita, Inoue Masumi
    Journal of UOEH, 2022年, 指定なし, 指定なし
  • Mechanisms for establishment of GABA signaling in adrenal medullary chromaffin cells.
    Harada Keita, Matsuoka Hidetada, Toyohira Yumiko, Yanagawa Yuchio, Inoue Masumi
    Journal of neurochemistry, 2021年07月, 指定なし, 指定なし
  • Storage of GABA in chromaffin granules and not in synaptic-like microvesicles in rat adrenal medullary cells.
    Harada Keita, Matsuoka Hidetada, Nakamura Jun, Fukuda Mitsunori, Inoue Masumi
    Journal of neurochemistry, 2010年07月, 査読あり, 指定なし
    筆頭著者
  • Inhibition of TASK1-like channels by muscarinic receptor stimulation in rat adrenal medullary cells.
    Inoue Masumi, Harada Keita, Matsuoka Hidetada, Sata Takeyoshi, Warashina Akira
    Journal of neurochemistry, 2008年08月, 査読あり, 指定なし
  • Identification and role of muscarinic receptor subtypes expressed in rat adrenal medullary cells.
    Harada Keita, Matsuoka Hidetada, Sata Takeyoshi, Warashina Akira, Inoue Masumi
    Journal of pharmacological sciences, 2011年, 査読あり, 指定なし
    筆頭著者
  • Molecular mechanisms supporting a paracrine role of GABA in rat adrenal medullary cells.
    Matsuoka Hidetada, Harada Keita, Endo Yutaka, Warashina Akira, Doi Yoshiaki, Nakamura Jun, Inoue Masumi
    The Journal of physiology, 2008年10月, 査読あり, 指定なし
  • Catecholamine secretion by chemical hypoxia in guinea-pig, but not rat, adrenal medullary cells: differences in mitochondria
    Harada K, Endo Y, Warashina A, Inoue M
    Neuroscience, 2015年06月, 査読あり, 招待無し
  • Regulation of α3-containing GABAA receptors in guinea-pig adrenal medullary cells by adrenal steroids.
    Inoue Masumi, Harada Keita, Nakamura Jun, Matsuoka Hidetada
    Neuroscience, 2013年12月, 査読あり, 指定なし
    ラスト(シニア)オーサー
  • Muscarinic receptors in adrenal chromaffin cells: physiological role and regulation of ion channels.
    Inoue Masumi, Matsuoka Hidetada, Harada Keita, Kao Lung-Sen
    Pflugers Archiv : European journal of physiology, 2018年01月, 査読あり, 指定なし
  • Nerve growth factor-induced endocytosis of TWIK-related acid-sensitive K⁺ 1 channels in adrenal medullary cells and PC12 cells.
    Matsuoka Hidetada, Harada Keita, Nakamura Jun, Inoue Masumi
    Pflugers Archiv : European journal of physiology, 2013年07月, 査読あり, 指定なし
  • Expression of p11 and Heteromeric TASK Channels in Rat Carotid Body Glomus Cells and Nerve Growth Factor-differentiated PC12 Cells.
    Matsuoka Hidetada, Pokorski Mieczyslaw, Harada Keita, Yoshimura Reiji, Inoue Masumi
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2020年10月, 査読あり, 招待無し
  • Localization of type-2 angiotensin II receptor in adrenal gland.
    Harada Keita, Matsuoka Hidetada, Fujimoto Naohiro, Endo Yutaka, Hasegawa Yoshitaka, Matsuo Akira, Kikuchi Yuta, Matsumoto Tetsuro, Inoue Masumi
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2010年07月, 査読あり, 指定なし
    筆頭著者
  • カフェインの暗算能力に対する効果の二重盲検法による検討
    白石 富美恵, 高橋 富美, 後藤 多佳子, 原田 景太, 草場 亜矢子, 森本 幸生
    福岡医学雑誌, 2000年04月, 査読なし, 指定なし
  • Heterogeneous levels of oxidative phosphorylation enzymes in rat adrenal glands.
    Ogawa Koichi, Harada Keita, Endo Yutaka, Sagawa Sueko, Inoue Masumi
    Acta histochemica, 2011年01月, 指定なし, 指定なし
  • Muscarinic Receptor Stimulation Does Not Inhibit Voltage-dependent Ca2+ Channels in Rat Adrenal Medullary Chromaffin Cells.
    Harada Keita, Inoue Masumi
    Acta histochemica et cytochemica, 2023年08月, 査読あり, 招待無し
    筆頭著者
  • Mechanisms for pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea-pig and mouse adrenal medullary cells.
    Inoue Masumi, Harada Keita, Matsuoka Hidetada
    European journal of pharmacology, 2020年04月, 指定なし, 指定なし
  • Immunocytochemistry of Acutely Isolated Adrenal Medullary Chromaffin Cells.
    Harada Keita, Matsuoka Hidetada, Inoue Masumi
    Methods in molecular biology (Clifton, N.J.), 2023年02月, 査読あり, 招待無し
    筆頭著者
  • TASK channels: channelopathies, trafficking, and receptor-mediated inhibition.
    Inoue Masumi, Matsuoka Hidetada, Harada Keita, Mugishima Go, Kameyama Masaki
    Pflugers Archiv : European journal of physiology, 2020年07月, 指定なし, 指定なし
  • Organelles containing inositol trisphosphate receptor type 2 in adrenal medullary cells.
    Endo Yutaka, Harada Keita, Fujishiro Naoji, Funahashi Hisasachi, Shioda Seiji, Prestwich Glenn D, Mikoshiba Katsuhiko, Inoue Masumi
    The journal of physiological sciences : JPS, 2006年12月, 指定なし, 指定なし
  • Subunit composition and role of Na+,K+-ATPases in ventricular myocytes.
    Harada Keita, Lin Hai, Endo Yutaka, Fujishiro Naoji, Sakamoto Yasuji, Inoue Masumi
    The journal of physiological sciences : JPS, 2006年02月, 指定なし, 指定なし