Essential elements for guiding patient segmentation in precision pharmacotherapy for rheumatoid arthritis: lessons up to 2025
Koshiro Sonomoto; Yoshiya Tanaka
Expert Opinion on Pharmacotherapy, 2026年05月

Emerging trends in the management of difficult-to-treat rheumatoid arthritis: targeted treatments and non-pharmacological interventions
György Nagy; Koshiro Sonomoto; András M Dorgó; Lilla Gunkl-Tóth; Yoshiya Tanaka
Rheumatology, 2026年05月

Short-chain fatty acid deficiency drives aberrant B cell differentiation in systemic lupus erythematosus.
Ryuichiro Kanda; Satoshi Kubo; Kaoru Yamagata; Shigeru Iwata; Yasuyuki Todoroki; Masanobu Ueno; Atsushi Nagayasu; Yurie Satoh-Kanda; Ippei Miyagawa; Koshiro Sonomoto; Yoshiya Tanaka; Shingo Nakayamada
Clinical immunology (Orlando, Fla.), 2026年04月

Effectiveness and Safety of Sarilumab in Polymyalgia Rheumatica: a retrospective study of the FIRST Registry.
Naoaki Ohkubo; Yusuke Miyazaki; Satoshi Kubo; Ippei Miyagawa; Koshiro Sonomoto; Yoshino Inoue; Yurie Satoh-Kanda; Hiroaki Tanaka; Masanobu Ueno; Atsushi Nagayasu; Takafumi Aritomi; Ryuichiro Kanda; Yuya Fujita; Masashi Funada; Hidenori Sakai; Kiyotake Yoshioka; Mayu Nishimoto; Kazuki Takahashi; Shingo Nakayamada; Yoshiya Tanaka
Modern rheumatology, 2026年03月

Biological/targeted synthetic DMARDs do not arrest bone loss in patients with rheumatoid arthritis: a long-term multicenter observational study.
Takafumi Aritomi; Koshiro Sonomoto; Shingo Nakayamada; Hiroaki Tanaka; Atsushi Nagayasu; Satoshi Kubo; Ippei Miyagawa; Ayako Yamaguchi; Naoaki Ohkubo; Yasuyuki Todoroki; Yurie Satoh-Kanda; Masanobu Ueno; Ryuichiro Kanda; Yuya Fujita; Masashi Funada; Hidenori Sakai; Satsuki Matsunaga; Hiroaki Tanaka; Masayuki Shinojima; Hiroki Kawamura; Kazuki Takahashi; Miyabi Ando; Kazuki Haru; Yusuke Miyazaki; Kentaro Hanami; Masao Nawata; Shunsuke Fukuyo; Keisuke Nakatsuka; Mikiko Tokunaga; Kazuyoshi Saito; Yoshiya Tanaka
Arthritis & rheumatology (Hoboken, N.J.), 2026年03月

Real-world effectiveness of b/tsDMARD switching in low-inflammatory difficult-to-treat rheumatoid arthritis: insights from the FIRST registry.
Hidenori Sakai; Koshiro Sonomoto; Shingo Nakayamada; Masanobu Ueno; Atsushi Nagayasu; Takafumi Aritomi; Hiroaki Tanaka; Satoshi Kubo; Ippei Miyagawa; Yasuyuki Todoroki; Yurie Satoh-Kanda; Yuya Fujita; Ryuichiro Kanda; Yoshiya Tanaka
RMD open, 2026年02月

Comparison of tofacitinib, baricitinib, upadacitinib and filgotinib: a 2-year observational study from FIRST registry.
Koshiro Sonomoto; Shingo Nakayamada; Hidenori Sakai; Masanobu Ueno; Hiroaki Tanaka; Atsushi Nagayasu; Takafumi Aritomi; Makoto Okawara; Akinori Nakata; Yoshiya Tanaka
RMD open, 2026年01月

Predicting the progression of difficult-to-treat rheumatoid arthritis by a machine learning scoring system, from the FIRST registry.
Masanobu Ueno; Koshiro Sonomoto; Hiroaki Tanaka; Atsushi Nagayasu; Takafumi Aritomi; Ippei Miyagawa; Satoshi Kubo; Yusuke Miyazaki; Yasuyuki Todoroki; Yurie Satoh-Kanda; Yuya Fujita; Hidenori Sakai; Shingo Nakayamada; Yoshiya Tanaka
RMD open, 2026年01月

Three-drug combination therapy to prevent glucocorticoid-associated osteonecrosis in patients with systemic lupus erythematosus: a proof-of-concept study.
Goro Motomura; Yojiro Arinobu; Hiroaki Niiro; Kazuoto Hiramoto; Yuko Kaneko; Masaru Kato; Shuhei Takeyama; Shunsuke Furuta; Hiroshi Nakajima; Ran Nakashima; Hajime Yoshifuji; Takeshi Kuroda; Koichi Amano; Masakazu Matsushita; Ken Yamaji; Koshiro Sonomoto; Yoshiya Tanaka; Naoko Himuro; Katsuhisa Miyake; Akihito Maruyama; Yoshifumi Tada; Atsushi Nomura; Masato Okada; Junji Kishimoto; Yasuharu Nakashima; Takuaki Yamamoto
Therapeutic advances in musculoskeletal disease, 2026年

Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis.
Atsushi Nagayasu; Yusuke Miyazaki; Koshiro Sonomoto; Satoshi Kubo; Ippei Miyagawa; Ayako Yamaguchi; Hiroaki Tanaka; Yasuyuki Todoroki; Masanobu Ueno; Takafumi Aritomi; Yuya Fujita; Hidenori Sakai; Katsunori Suzuki; Shingo Nakayamada; Yoshiya Tanaka
Rheumatology and therapy, 2025年08月

Real-World Safety and Efficacy of Targeted Therapies in Rheumatoid Arthritis: A 5-Year, 5130-Case Follow-Up from FIRST Registry.
Koshiro Sonomoto; Shingo Nakayamada; Hiroaki Tanaka; Atsushi Nagayasu; Yoshiya Tanaka
Rheumatology and therapy, 2025年06月

Targeted Therapies for Rheumatoid Arthritis in Super-Elderly Society: Insights From FIRST Registry, Japan.
Koshiro Sonomoto; Yoshiya Tanaka
International journal of rheumatic diseases, 2025年04月

Association of peripheral CD8+ T cell activation with disease activity and treatment resistance in systemic lupus erythematosus.
Yuya Fujita; Shingo Nakayamada; Satoshi Kubo; Yusuke Miyazaki; Koshiro Sonomoto; Hiroaki Tanaka; Yoshiya Tanaka
RMD open, 2025年02月

Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus.
Masanobu Ueno; Shigeru Iwata; Kaoru Yamagata; Yasuyuki Todoroki; Koshiro Sonomoto; Atsushi Nagayasu; Ippei Miyagawa; Satoshi Kubo; Yusuke Miyazaki; Hiroko Miyata; Ryuichiro Kanda; Takafumi Aritomi; Shingo Nakayamada; Yoshiya Tanaka
RMD open, 2024年12月

Methotrexate, Tofacitinib, and Biologic Disease-Modifying Antirheumatic Drug Safety and Effectiveness Among Patients with Rheumatoid Arthritis in Japan: CorEvitas Registry Observational Study.
Yoshiya Tanaka; Mitsumasa Kishimoto; Koshiro Sonomoto; Koichi Amano; Masayoshi Harigai; Alina Onofrei; Jacqueline O'Brien; Zachary Margolin; Christine Barr; Yasushi Mizuno; Ekta Agarwal; Naonobu Sugiyama; Hisashi Yamanaka
Rheumatology and therapy, 2024年10月

Safety and efficacy of anifrolumab therapy in systemic lupus erythematosus in real-world clinical practice: LOOPS registry.
Yusuke Miyazaki; Masashi Funada; Shingo Nakayamada; Koshiro Sonomoto; Hiroaki Tanaka; Kentaro Hanami; Shunsuke Fukuyo; Satoshi Kubo; Ayako Yamaguchi; Ippei Miyagawa; Yasuyuki Todoroki; Masanobu Ueno; Yoshiya Tanaka
Rheumatology (Oxford, England), 2024年09月

Biological/targeted synthetic DMARDs do not arrest bone loss in patients with rheumatoid arthritis: a multicenter prospective observational study.
Koshiro Sonomoto; Shingo Nakayamada; Yoshihisa Fujino; Hiroko Miyata; Satoshi Kubo; Yuya Fujita; Yoshino Inoue; Satsuki Matsunaga; Shigeru Iwata; Kentaro Hanami; Yasuyuki Todoroki; Hiroko Yoshinari-Korekoda; Akio Kawabe; Ayako Yamaguchi; Masanobu Ueno; Yurie Satoh-Kanda; Ryuichiro Kanda; Masashi Funada; Naoaki Ohkubo; Katsuhide Kusaka; Shumpei Kosaka; Atsushi Nagayasu; Shunsuke Fukuyo; Masao Nawata; Yusuke Miyazaki; Mikiko Tokunaga; Kenichi Tanaka; Yosuke Okada; Yoshiya Tanaka
Rheumatology (Oxford, England), 2024年08月

Predictors of functional improvement and pain reduction in rheumatoid arthritis patients who achieved low disease activity with disease-modifying antirheumatic drugs: a retrospective study of the FIRST Registry
Sae Ochi; Koshiro Sonomoto; Shingo Nakayamada; Yoshiya Tanaka
ARTHRITIS RESEARCH & THERAPY, 2024年07月

Modifying T cell phenotypes using TYK2 inhibitor and its implications for the treatment of systemic lupus erythematosus.
Yurie Satoh-Kanda; Shingo Nakayamada; Satoshi Kubo; Kaoru Yamagata; Aya Nawata; Hiroaki Tanaka; Shunpei Kosaka; Ryuichiro Kanda; Shan Yu; Yuya Fujita; Koshiro Sonomoto; Yoshiya Tanaka
RMD open, 2024年06月

CT informs detection and treatment options in rheumatoid arthritis complicated by pulmonary non-tuberculous mycobacterial disease from the FIRST registry.
Masashi Funada; Yusuke Miyazaki; Shingo Nakayamada; Koshiro Sonomoto; Satoshi Kubo; Ippei Miyagawa; Hiroaki Tanaka; Yoshiya Tanaka
RMD open, 2024年06月

A Machine Learning Approach for Prediction of CDAI Remission with TNF Inhibitors: A Concept of Precision Medicine from the FIRST Registry.
Koshiro Sonomoto; Yoshihisa Fujino; Hiroaki Tanaka; Atsushi Nagayasu; Shingo Nakayamada; Yoshiya Tanaka
Rheumatology and therapy, 2024年06月

Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping.
Hiroaki Tanaka; Yukinori Okada; Shingo Nakayamada; Yusuke Miyazaki; Kyuto Sonehara; Shinichi Namba; Suguru Honda; Yuya Shirai; Kenichi Yamamoto; Satoshi Kubo; Katsunori Ikari; Masayoshi Harigai; Koshiro Sonomoto; Yoshiya Tanaka
Annals of the rheumatic diseases, 2024年01月

Generation-Dependent Retention Rates and Reasons for Discontinuation of Molecular Targeted Therapies in Patients with Rheumatoid Arthritis: From FIRST Registry.
Satoshi Kubo; Yusuke Miyazaki; Yasuyuki Todoroki; Atsushi Nagayasu; Ryuichiro Kanda; Takafumi Aritomi; Satsuki Matsunaga; Masanobu Ueno; Ippei Miyagawa; Koshiro Sonomoto; Kentaro Hanami; Shingo Nakayamada; Yoshiya Tanaka
Rheumatology and therapy, 2023年12月

Computed tomography for malignancy screening in patients with rheumatoid arthritis before initiation of disease modifying antirheumatic drug.
Hiroko Miyata; Koshiro Sonomoto; Shunsuke Fukuyo; Shingo Nakayamada; Kazuhisa Nakano; Shigeru Iwata; Yusuke Miyazaki; Akio Kawabe; Takatoshi Aoki; Yoshiya Tanaka
Rheumatology (Oxford, England), 2023年10月

Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus.
Yuya Fujita; Shigeru Iwata; Shinsuke Hidese; Sayuri Ishiwata; Satoru Ide; Hiroaki Tanaka; Koshiro Sonomoto; Yusuke Miyazaki; Shingo Nakayamada; Atsuko Ikenouchi; Kotaro Hattori; Hiroshi Kunugi; Reiji Yoshimura; Yoshiya Tanaka
Rheumatology (Oxford, England), 2023年10月

Cohort-wide Immuno-phenotype Deconvolute Immunological and Clinical Heterogeneity Across Autoimmune Rheumatic Diseases
Hiroaki Tanaka; Yukinori Okada; Shingo Nakayamada; Yusuke Miyazaki; Kyuto Sonehara; Shinichi Namba; Suguru Honda; Yuya Shirai; Kenichi Yamamoto; Katsunori Ikari; Masayoshi Harigai; Koshiro Sonomoto; Yoshiya Tanaka
ARTHRITIS & RHEUMATOLOGY, 2023年10月

High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production.
Koshiro Sonomoto; Rui Song; Daniel Eriksson; Anne M Hahn; Xianyi Meng; Pang Lyu; Shan Cao; Ning Liu; R Verena Taudte; Stefan Wirtz; Yoshiya Tanaka; Thomas H Winkler; Georg Schett; Didier Soulat; Aline Bozec
Cell reports, 2023年07月

TGF-β3 in differentiation and function of Tph-like cells and its relevance to disease activity in patients with systemic lupus erythematosus.
Yu Shan; Shingo Nakayamada; Aya Nawata; Kaoru Yamagata; Koshiro Sonomoto; Hiroaki Tanaka; Yurie Satoh-Kanda; Mai-Phuong Nguyen; Yasuyuki Todoroki; Atsushi Nagayasu; Masanobu Ueno; Ryuichiro Kanda; Yuya Fujita; Tong Zhang; He Hao; Jieqing Zhou; Xiaoxue Ma; Junpei Anan; Anh Phuong Nguyen; Yoshiya Tanaka
Rheumatology (Oxford, England), 2023年07月

Malignancies and rheumatoid arthritis, csDMARDs, biological DMARDs, and JAK inhibitors: challenge and outlook.
Koshiro Sonomoto; Yoshiya Tanaka
Expert review of clinical immunology, 2023年

Enhancer RNA commits osteogenesis via microRNA-3129 expression in human bone marrow-derived mesenchymal stem cells.
Anh Phuong Nguyen; Kaoru Yamagata; Shigeru Iwata; Gulzhan Trimova; Tong Zhang; Yu Shan; Mai-Phuong Nguyen; Koshiro Sonomoto; Shingo Nakayamada; Shigeaki Kato; Yoshiya Tanaka
Inflammation and regeneration, 2022年09月

Characteristics and Treatment-selection in Patients with Rheumatoid Arthritis and with Inadequate Response to Janus Kinase Inhibitors
Yusuke Miyazaki; Shingo Nakayamada; Satoshi Kubo; Koshiro Sonomoto; Yoshino Inoue; Shunsuke Fukuyo; Kentaro Hanami; Yoshiya Tanaka
ARTHRITIS & RHEUMATOLOGY, 2022年09月

T helper cells expressing fractalkine receptor and bearing T follicular helper 1-like cell functions in patients with IgG4-related disease.
Yoshino Inoue; Shingo Nakayamada; Satoshi Kubo; Kaoru Yamagata; Koshiro Sonomoto; Shigeru Iwata; Yusuke Miyazaki; Yoshiya Tanaka
Rheumatology (Oxford, England), 2022年08月

Efficacy and safety of belimumab during maintenance therapy in patients with systemic lupus erythematosus.
Yusuke Miyazaki; Shingo Nakayamada; Koshiro Sonomoto; Akio Kawabe; Yoshino Inoue; Naoaki Okubo; Shigeru Iwata; Kentaro Hanami; Yoshiya Tanaka
Rheumatology (Oxford, England), 2022年08月

An enhanced mitochondrial function through glutamine metabolism in plasmablast differentiation in systemic lupus erythematosus.
Maiko Hajime Sumikawa; Shigeru Iwata; Mingzeng Zhang; Hiroko Miyata; Masanobu Ueno; Yasuyuki Todoroki; Atsushi Nagayasu; Ryuichiro Kanda; Koshiro Sonomoto; Keiichi Torimoto; Seunghyun Lee; Shingo Nakayamada; Kazuo Yamamoto; Yosuke Okada; Yoshiya Tanaka
Rheumatology (Oxford, England), 2022年07月

mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors.
Mingzeng Zhang; Shigeru Iwata; Koshiro Sonomoto; Masanobu Ueno; Yuya Fujita; Junpei Anan; Yusuke Miyazaki; Naoaki Ohkubo; Maiko Hajime Sumikawa; Yasuyuki Todoroki; Hiroko Miyata; Atsushi Nagayasu; Ryuichiro Kanda; He Hao; Gulzhan Trimova; Seunghyun Lee; Shingo Nakayamada; Kei Sakata; Yoshiya Tanaka
Rheumatology (Oxford, England), 2022年07月

Prophylaxis against pneumocystis pneumonia in rheumatoid arthritis patients treated with b/tsDMARDs: insights from 3787 cases in the FIRST registry.
Koshiro Sonomoto; Hiroaki Tanaka; Tuan Manh Nguyen; Hiroko Yoshinari; Kazuhisa Nakano; Shingo Nakayamada; Yoshiya Tanaka
Rheumatology (Oxford, England), 2022年05月

Impact of serum interleukin-22 as a biomarker for the differential use of molecular targeted drugs in psoriatic arthritis: a retrospective study.
Ippei Miyagawa; Shingo Nakayamada; Masanobu Ueno; Yusuke Miyazaki; Shigeru Iwata; Satoshi Kubo; Koshiro Sonomoto; Junpei Anan; Naoaki Ohkubo; Yoshino Inoue; Yoshiya Tanaka
Arthritis research & therapy, 2022年04月

Preferable outcome of Janus kinase inhibitors for a group of difficult-to-treat rheumatoid arthritis patients: from the FIRST Registry.
Sae Ochi; Koshiro Sonomoto; Shingo Nakayamada; Yoshiya Tanaka
Arthritis research & therapy, 2022年03月

Estrogen-mediated downregulation of HIF-1α signaling in B lymphocytes influences postmenopausal bone loss.
Xianyi Meng; Zhen Lin; Shan Cao; Iga Janowska; Koshiro Sonomoto; Darja Andreev; Knab Katharina; Jinming Wen; Karl Xaver Knaup; Michael Sean Wiesener; Gerhard Krönke; Marta Rizzi; Georg Schett; Aline Bozec
Bone research, 2022年02月

Epstein-Barr virus-induced gene 3 commits human mesenchymal stem cells to differentiate into chondrocytes via endoplasmic reticulum stress sensor.
Tong Zhang; Kaoru Yamagata; Shigeru Iwata; Koshiro Sonomoto; Gulzhan Trimova; Anh Phuong Nguyen; He Hao; Yu Shan; Mai-Phuong Nguyen; Shingo Nakayamada; Yoshiya Tanaka
PloS one, 2022年

Pathological role of activated mTOR in CXCR3+ memory B cells of rheumatoid arthritis.
Shigeru Iwata; Mingzeng Zhang; Maiko Hajime; Naoaki Ohkubo; Koshiro Sonomoto; Keiichi Torimoto; Yukihiro Kitanaga; Gulzhan Trimova; Yasuyuki Todoroki; Hiroko Miyata; Masanobu Ueno; Atsushi Nagayasu; Ryuichiro Kanda; Kazuhisa Nakano; Shingo Nakayamada; Kei Sakata; Yoshiya Tanaka
Rheumatology (Oxford, England), 2021年11月

Comparison of Belimumab and Standard of Care by Inverse Probability of Treatment Weighting Analyses Based on Propensity Score in Patients with Systemic Lupus Erythematosus in the Maintenance Phase
Yusuke Miyazaki; Shingo Nakayamada; Shigeru Iwata; Kentaro Hanami; Shunsuke Fukuyo; Koshiro Sonomoto; Akio Kawabe; Yoshino Inoue; Naoaki Okubo; Yoshiya Tanaka
ARTHRITIS & RHEUMATOLOGY, 2021年09月

Skeletal unloading reduces cluster of differentiation (CD) 38 expression in the bone marrow and osteoblasts of mice.
Kuniaki Moridera; Soshi Uchida; Shinya Tanaka; Kunitaka Menuki; Hajime Utsunomiya; Kunihiro Yamaoka; Koshiro Sonomoto; Yoshiya Tanaka; Akinori Sakai
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2020年03月

Spontaneous Differentiation of Human Mesenchymal Stem Cells on Poly-Lactic-Co-Glycolic Acid Nano-Fiber Scaffold.
Koshiro Sonomoto; Kunihiro Yamaoka; Hiroaki Kaneko; Kaoru Yamagata; Kei Sakata; Xiangmei Zhang; Masahiro Kondo; Yukichi Zenke; Ken Sabanai; Shingo Nakayamada; Akinori Sakai; Yoshiya Tanaka
PloS one, 2016年

Contribution of the Interleukin-6/STAT-3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem Cells.
Masahiro Kondo; Kunihiro Yamaoka; Kei Sakata; Koshiro Sonomoto; Lin Lin; Kazuhisa Nakano; Yoshiya Tanaka
Arthritis & rheumatology (Hoboken, N.J.), 2015年05月

[Relevance of involvement of tofacitinib in T cell subsets to clinical courses and adverse events in patients with rheumatoid arthritis].
Koshiro Sonomoto; Yohisya Tanaka
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2015年

[Mesenchymal stem cells for the treatment and repair of inflammatory arthritis].
Yoshiya Tanaka; Koshiro Sonomoto; Masahiro Kondo; Koichi Oshita; Xiang-Mei Zhang; Shunsuke Fukuyo; Kunihiro Yamaoka
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2015年

IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent.
Shunsuke Fukuyo; Kunihiro Yamaoka; Koshiro Sonomoto; Koichi Oshita; Yosuke Okada; Kazuyoshi Saito; Yasuhiro Yoshida; Tamotsu Kanazawa; Yasuhiro Minami; Yoshiya Tanaka
Rheumatology (Oxford, England), 2014年07月

[An approach to bone and cartilage repair of rheumatoid arthritis by mesenchymal stem cells].
Koshiro Sonomoto; Kunihiro Yamaoka; Yoshiya Tanaka
Journal of UOEH, 2014年06月

Effects of tofacitinib on lymphocytes in rheumatoid arthritis: relation to efficacy and infectious adverse events.
Koshiro Sonomoto; Kunihiro Yamaoka; Satoshi Kubo; Shintaro Hirata; Shunsuke Fukuyo; Keisuke Maeshima; Katsunori Suzuki; Kazuyoshi Saito; Yoshiya Tanaka
Rheumatology (Oxford, England), 2014年05月

[Case report; a case of acetaminophen-induced hypersensitivity vasculitis].
Tomoya Shibahara; Atsushi Moriwaki; Koshiro Sonomoto; Katsuyuki Katahira; Aimi Enokizu; Kaori Kato; Tatsuro Shimokama; Satoru Kawakami; Tomotoshi Imanaga
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014年01月

Local delivery of mesenchymal stem cells with poly-lactic-co-glycolic acid nano-fiber scaffold suppress arthritis in rats.
Xiangmei Zhang; Kunihiro Yamaoka; Koshiro Sonomoto; Hiroaki Kaneko; Makoto Satake; Yuka Yamamoto; Masahiro Kondo; Jidong Zhao; Ippei Miyagawa; Kaoru Yamagata; Shunsuke Fukuyo; Yosuke Okada; Yoshiya Tanaka
PloS one, 2014年

Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis.
Sonosuke Yukawa; Kunihiro Yamaoka; Norifumi Sawamukai; Shohei Shimajiri; Satoshi Kubo; Ippei Miyagawa; Koshiro Sonomoto; Kazuyoshi Saito; Yoshiya Tanaka
Modern rheumatology, 2013年11月

Three-Dimension Culture Of Mesenchymal Stem Cells With Nano-Fiber Scaffold Induces Chondrogenesis and Osteogenesis.
Kunihiro Yamaoka; Koshiro Sonomoto; Xiangmei Zhang; Masahiro Kondo; Shunsuke Fukuyo; Makoto Satake; Hiroaki Kaneko; Kazuhisa Nakano; Yosuke Okada; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2013年10月

IL-17 inhibits chondrogenic differentiation of human mesenchymal stem cells.
Masahiro Kondo; Kunihiro Yamaoka; Koshiro Sonomoto; Shunsuke Fukuyo; Koichi Oshita; Yosuke Okada; Yoshiya Tanaka
PloS one, 2013年

Mesenchymal Stem Cells Differentiate Into Osteoblasts in Response to Inflammation
Koshiro Sonomoto; Kunihiro Yamaoka; Koichi Oshita; Shunsuke Fukuyo; Xiangmei Zhang; Kazuhisa Nakano; Yosuke Okada; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2012年10月

Delivering Mesenchymal Stem Cells to Arthritic Joints with Nano-Fiber Scaffold Resulted in Inhibition of Arthritis and Joint Damage in Arthritis Models
Xiangmei Zhang; Kunihiro Yamaoka; Koshiro Sonomoto; Masahiro Kondo; Shunsuke Fukuyo; Makoto Satake; Hiroaki Kaneko; Kazuhisa Nakano; Shingo Nakayamada; Yosuke Okada; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2012年10月

Correlation of A Multi-Biomarker Disease Activity (VECTRA™ DA) Score with Clinical Disease Activity and Its Components with Radiographic Progression in Rheumatoid Arthritis Patients Treated with Tofacitinib.
Kunihiro Yamaoka; Satoshi Kubo; Koshiro Sonomoto; Shintaro Hirata; Guy Cavet; Rebecca Bolce; Michael W. Rowe; David Chernoff; Nadine Defranoux; Kazuyoshi Saito; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2012年10月

Interleukin-1β induces differentiation of human mesenchymal stem cells into osteoblasts via the Wnt-5a/receptor tyrosine kinase-like orphan receptor 2 pathway.
Koshiro Sonomoto; Kunihiro Yamaoka; Koichi Oshita; Shunsuke Fukuyo; Xiangmei Zhang; Kazuhisa Nakano; Yosuke Okada; Yoshiya Tanaka
Arthritis and rheumatism, 2012年10月

AJAK inhibitor, tofacitinibreduces IL-6 and matrix metalloproteinase-3 productionin rheumatoid arthritis with suppressed cartilage destruction
Kunihiro Yamaoka; Satoshi Kubo; Koshiro Sonomoto; Keisuke Maeshima; Yoshiya Tanaka
ARTHRITIS RESEARCH & THERAPY, 2012年

[Anti-rheumatic effect of JAK-inhibitors].
Kunihiro Yamaoka; Keisuke Maeshima; Satoshi Kubo; Koshiro Sonomoto; Yoshiya Tanaka
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2012年

Tofacitinib Reduces Interleukin-6 and Matrix Metalloproteinase-3 Production and Inhibits Cartilage Destruction in Rheumatoid Arthritis
Kunihiro Yamaoka; Satoshi Kubo; Keisuke Maeshima; Koshiro Sonomoto; Kazuhisa Nakano; Norifumi Sawamukai; Masao Nawata; Kazuyoshi Saito; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2011年10月

Tofacitinib Reduces Interferon-γ and Interleukin-17 Production From CD4+T Cells in Patients with Rheumatoid Arthritis.
Satoshi Kubo; Kunihiro Yamaoka; Koshiro Sonomoto; Keisuke Maeshima; Shintaro Hirata; Kazuhisa Nakano; Norifumi Sawamukai; Masao Nawata; Shigeru Iwata; Kazuyoshi Saito; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2011年10月

Relevance of Involvement of Tofacitinib in T Cell Subsets to Clinical Courses in Patients with Rheumatoid Arthritis.
Koshiro Sonomoto; Kunihiro Yamaoka; Satoshi Kubo; Keisuke Maeshima; Ippei Miyagawa; Kazuhisa Nakano; Norifumi Sawamukai; Kazuyoshi Saito; Yoshiya Tanaka
ARTHRITIS AND RHEUMATISM, 2011年10月

Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production.
Koichi Oshita; Kunihiro Yamaoka; Nobuyuki Udagawa; Shunsuke Fukuyo; Koshiro Sonomoto; Keisuke Maeshima; Ryuji Kurihara; Kazuhisa Nakano; Kazuyoshi Saito; Yosuke Okada; Kenji Chiba; Yoshiya Tanaka
Arthritis and rheumatism, 2011年06月

Influenza virus B-associated hemophagocytic syndrome and recurrent pericarditis in a patient with systemic lupus erythematosus.
Yoshiro Horai; Tomoya Miyamura; Soichiro Takahama; Koshiro Sonomoto; Masataka Nakamura; Hitoshi Ando; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu
Modern rheumatology, 2010年04月

Discontinuation of etanercept in patients with rheumatoid arthritis who were in clinical remission.
Tomoya Miyamura; Koshiro Sonomoto; Masataka Nakamura; Yoshiro Horai; Soichiro Takahama; Hitoshi Ando; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu
Clinical rheumatology, 2010年01月

[Microscopic polyangiitis in a patient on hemodialysis : a case report].
Yoshiro Horai; Tomoya Miyamura; Soichiro Takahama; Koshiro Sonomoto; Masataka Nakamura; Hitoshi Ando; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年12月

[A clinical study of five cases demonstrating relapsing polychondritis].
Rumi Minami; Tomoya Miyamura; Masataka Nakamura; Koshiro Sonomoto; Yoshiro Horai; Soichiro Takahama; Hitoshi Ando; Masahiro Yamamoto; Eiichi Suematsu
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年08月

[Diagnostic utility of anti-cyclic citrullinated peptide antibody in early rheumatoid arthritis].
Tomoya Miyamura; Hideyuki Watanabe; Soichiro Takahama; Koshiro Sonomoto; Masataka Nakamura; Hitosi Ando; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年04月

[A case of systemic lupus erythematosus complicated with autoimmune hepatitis and thrombotic thrombocytic purpura].
Koshiro Sonomoto; Tomoya Miyamura; Hideyuki Watanabe; Soichiro Takahama; Masataka Nakamura; Hitoshi Ando; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年04月

[Thrombotic thrombocytopenic purpura in patients with systemic lupus erythematosus].
Tomoya Miyamura; Hideyuki Watanabe; Soichiro Takahama; Koshiro Sonomoto; Masataka Nakamura; Hitosi Ando; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2008年06月

[A case of polyarteritis nodosa successfully treated by rituximab].
Koshiro Sonomoto; Tomaya Miyamura; Hideyuki Watanabe; Soichiro Takahama; Masataka Nakamura; Hitoshi Ando; Rumi Minami; Masahiro Yamamoto; Tomoko Saito; Shuhei Imayama; Chisato Hosokawa; Eiichi Suematsu
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2008年04月

トファシチニブのリンパ球への影響と臨床効果および副作用との関連性
園本 格士朗, 山岡 邦宏, 田中 良哉
リウマチ科, 2015年01月, 指定なし, 指定なし
筆頭著者

関節リウマチに対するトファシチニブ(CP-690、550)の効果
山岡 邦宏, 久保 智史, 園本 格士朗, 前島 圭佑, 田中 良哉
リウマチ科, 2012年07月, 指定なし, 指定なし

成人スチル病患者における銅欠乏症　当院での経験と発症危険因子の検討
安藤 翔治, 春田 典子, 園本 格士朗, 鳥越 雅隆, 末永 康夫
九州リウマチ, 2021年09月, 指定なし, 指定なし

後毛細血管性肺高血圧症(PH)が疑われたオーバーラップ症候群の一例
角 華織, 園本 格士朗, 木村 大作, 若洲 翔, 古賀 康雅, 高原 由樹, 末永 康夫
九州リウマチ, 2017年03月, 指定なし, 指定なし

末梢神経障害を初発症状としたメトトレキサート関連リンパ増殖性疾患の1例
古賀 康雅, 園本 格士朗, 木村 大作, 大塚 健一朗, 末永 康夫, 伊藤 能清, 近藤 大祐, 吉河 康二
九州リウマチ, 2017年03月, 指定なし, 指定なし

二重膜濾過血漿交換療法導入翌日に著明に改善した神経精神全身性ループスエリテマトーデスの一例
高原 由樹, 園本 格士朗, 木村 大作, 古賀 康雅, 若洲 翔, 角 華織, 末永 康夫
九州リウマチ, 2017年03月, 指定なし, 指定なし

肥厚性硬膜炎で再発した巨細胞性動脈炎の一例
園本 格士朗, 木村 大作, 下村 悠太朗, 野上 健一郎, 古賀 康雅, 横山 淳, 末永 康夫
九州リウマチ, 2016年03月, 指定なし, 指定なし
筆頭著者

経過中に顕微鏡的多発血管炎を発症した関節リウマチの一例
園本 格士朗, 宮村 知也, 中村 真隆, 寶來 吉朗, 高濱 宗一郎, 安藤 仁, 南 留美, 山本 政弘, 末松 栄一
九州リウマチ, 2009年03月, 指定なし, 指定なし
筆頭著者

シクロフォスファミドパルス療法が奏効した難治性再発性多発軟骨炎の1例
寶來 吉朗, 宮村 知也, 園本 格士朗, 中村 真隆, 高濱 宗一郎, 安藤 仁, 南 留美, 山本 政弘, 末松 栄一
九州リウマチ, 2009年03月, 指定なし, 指定なし
筆頭著者

混合性結合組織病に合併する心肺病変の臨床的検討
南 留美, 宮村 知也, 渡邉 秀之, 園本 格士朗, 中村 真隆, 高濱 宗一郎, 山本 政弘, 末松 栄一
九州リウマチ, 2008年09月, 指定なし, 指定なし

特発性血小板減少性紫斑病を合併した関節リウマチの臨床的検討
末松 栄一, 宮村 知也, 園本 格士朗, 中村 真隆, 寶來 吉朗, 渡邉 秀之, 高濱 宗一郎, 安藤 仁, 南 留美, 山本 政弘
九州リウマチ, 2008年09月, 指定なし, 指定なし

門脈血栓症を合併した全身性エリテマトーデスの一例
寶來 吉朗, 宮村 知也, 渡邉 秀之, 高濱 宗一郎, 園本 格士朗, 中村 真隆, 安藤 仁, 南 留美, 山本 政弘, 末松 栄一
九州リウマチ, 2008年09月, 指定なし, 指定なし

継続的血漿交換療法と免疫抑制剤の併用療法が奏効したTTP合併SLEの一例
中村 真隆, 宮村 知也, 渡邉 秀之, 高濱 宗一郎, 園本 格士朗, 安藤 仁, 寶來 吉朗, 南 留美, 山本 政弘, 末松 栄一
九州リウマチ, 2008年09月, 指定なし, 指定なし

FDG-PET検査を契機に診断された血管炎症候群の一例
高濱 宗一郎, 宮村 知也, 甲斐 亮三, 渡邉 秀之, 園本 格士朗, 南 留美, 山本 政弘, 末松 栄一
九州リウマチ, 2008年03月, 指定なし, 指定なし

γ-globulin大量療法が奏効した結節性多発動脈炎の一例
園本 格士朗, 宮村 知也, 渡邉 秀之, 高濱 宗一郎, 南 留美, 山本 政弘, 末松 栄一, 齊藤 知子, 今山 修平, 細川 知聡
九州リウマチ, 2007年09月, 指定なし, 指定なし
筆頭著者

【炎症疾患におけるキナーゼ阻害薬の進歩】JAK阻害薬tofacitinibの抗リウマチ作用
山岡 邦宏, 前島 圭佑, 久保 智史, 園本 格士朗, 田中 良哉
医学のあゆみ, 2012年02月, 指定なし, 指定なし

長期グルココルチコイド治療が血清銅・亜鉛濃度に与える影響の検討
安藤翔治, 園本格士朗, 末永康夫, 鳥越雅隆, 春田典子
医療, 2023年10月, 査読あり, 招待無し

アセトアミノフェンによる過敏性血管炎の1例
芝原 友也, 森脇 篤史, 園本 格士朗, 片平 雄之, 榎津 愛実, 加藤 香織, 下釜 達朗, 川上 覚, 今永 知俊
日本内科学会雑誌, 2014年01月, 指定なし, 指定なし

膠原病患者のニューモシスチス肺炎発症リスクと予防方法　基準を設け予防投与を検討する。予防投与にはST合剤を用いる
園本 格士朗, 山岡 邦宏
日本医事新報, 2022年05月, 指定なし, 指定なし
筆頭著者, 責任著者

短期間で銅欠乏症を呈したと考えられた成人スチル病の一例
安藤 翔治, 宮平 明奈, 稲富 悠夏, 宮田 萌, 桑原 淳子, 末永 康夫, 園本 格士朗
日本病態栄養学会誌, 2020年10月, 指定なし, 指定なし
ラスト(シニア)オーサー

間葉系幹細胞による関節リウマチの骨軟骨再生へのアプローチ
園本 格士朗, 山岡 邦宏, 田中 良哉
産業医科大学雑誌, 2014年06月, 指定なし, 指定なし
筆頭著者

Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping.
Tanaka Hiroaki, Okada Yukinori, Nakayamada Shingo, Miyazaki Yusuke, Sonehara Kyuto, Namba Shinichi, Honda Suguru, Shirai Yuya, Yamamoto Kenichi, Kubo Satoshi, Ikari Katsunori, Harigai Masayoshi, Sonomoto Koshiro, Tanaka Yoshiya
Annals of the rheumatic diseases, 2024年01月, 査読あり, 招待無し

Contribution of the Interleukin-6/STAT-3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem Cells.
Kondo Masahiro, Yamaoka Kunihiro, Sakata Kei, Sonomoto Koshiro, Lin Lin, Nakano Kazuhisa, Tanaka Yoshiya
Arthritis & rheumatology (Hoboken, N.J.), 2015年05月, 指定なし, 指定なし

Interleukin-1β induces differentiation of human mesenchymal stem cells into osteoblasts via the Wnt-5a/receptor tyrosine kinase-like orphan receptor 2 pathway.
Sonomoto Koshiro, Yamaoka Kunihiro, Oshita Koichi, Fukuyo Shunsuke, Zhang Xiangmei, Nakano Kazuhisa, Okada Yosuke, Tanaka Yoshiya
Arthritis and rheumatism, 2012年10月, 指定なし, 指定なし
筆頭著者

Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production.
Oshita Koichi, Yamaoka Kunihiro, Udagawa Nobuyuki, Fukuyo Shunsuke, Sonomoto Koshiro, Maeshima Keisuke, Kurihara Ryuji, Nakano Kazuhisa, Saito Kazuyoshi, Okada Yosuke, Chiba Kenji, Tanaka Yoshiya
Arthritis and rheumatism, 2011年06月, 指定なし, 指定なし

Predictors of functional improvement and pain reduction in rheumatoid arthritis patients who achieved low disease activity with disease-modifying antirheumatic drugs: a retrospective study of the FIRST Registry.
Ochi Sae, Sonomoto Koshiro, Nakayamada Shingo, Tanaka Yoshiya
Arthritis research & therapy, 2024年07月, 査読あり, 招待無し

Impact of serum interleukin-22 as a biomarker for the differential use of molecular targeted drugs in psoriatic arthritis: a retrospective study.
Miyagawa Ippei, Nakayamada Shingo, Ueno Masanobu, Miyazaki Yusuke, Iwata Shigeru, Kubo Satoshi, Sonomoto Koshiro, Anan Junpei, Ohkubo Naoaki, Inoue Yoshino, Tanaka Yoshiya
Arthritis research & therapy, 2022年04月, 査読あり, 招待無し

Preferable outcome of Janus kinase inhibitors for a group of difficult-to-treat rheumatoid arthritis patients: from the FIRST Registry.
Ochi Sae, Sonomoto Koshiro, Nakayamada Shingo, Tanaka Yoshiya
Arthritis research & therapy, 2022年03月, 査読あり, 招待無し

Estrogen-mediated downregulation of HIF-1α signaling in B lymphocytes influences postmenopausal bone loss.
Meng Xianyi, Lin Zhen, Cao Shan, Janowska Iga, Sonomoto Koshiro, Andreev Darja, Katharina Knab, Wen Jinming, Knaup Karl Xaver, Wiesener Michael Sean, Krönke Gerhard, Rizzi Marta, Schett Georg, Bozec Aline
Bone research, 2022年02月, 指定なし, 指定なし

High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production
Sonomoto Koshiro, Song Rui, Eriksson Daniel, Hahn Anne M, Meng Xianyi, Lyu Pang, Cao Shan, Liu Ning, Taudte R Verena, Wirtz Stefan, Tanaka Yoshiya, Winkler Thomas H, Schett Georg, Soulat Didert, Bozec Aline.
Cell Reports, 2023年07月, 査読あり, 招待無し
筆頭著者

Residual symptoms: Unmet needs for rheumatoid arthritis patients who achieved low clinical disease activity
Sae Ochi, Koshiro Sonomoto, Yoshiya Tanaka
Current Rheumatology Research, 2024年10月, 査読あり, 招待無し

Malignancies and rheumatoid arthritis, csDMARDs, biological DMARDs, and JAK inhibitors: challenge and outlook.
Sonomoto Koshiro, Tanaka Yoshiya
Expert review of clinical immunology, 2023年, 査読あり, 招待無し
筆頭著者

Enhancer RNA commits osteogenesis via microRNA-3129 expression in human bone marrow-derived mesenchymal stem cells.
Nguyen Anh Phuong, Yamagata Kaoru, Iwata Shigeru, Trimova Gulzhan, Zhang Tong, Shan Yu, Nguyen Mai-Phuong, Sonomoto Koshiro, Nakayamada Shingo, Kato Shigeaki, Tanaka Yoshiya
Inflammation and regeneration, 2022年09月, 査読あり, 招待無し

Targeted Therapies for Rheumatoid Arthritis in Super-Elderly Society: Insights From FIRST Registry, Japan.
Sonomoto Koshiro, Tanaka Yoshiya
International journal of rheumatic diseases, 2025年04月, 査読あり, 招待有り
筆頭著者

Skeletal unloading reduces cluster of differentiation (CD) 38 expression in the bone marrow and osteoblasts of mice.
Moridera Kuniaki, Uchida Soshi, Tanaka Shinya, Menuki Kunitaka, Utsunomiya Hajime, Yamaoka Kunihiro, Sonomoto Koshiro, Tanaka Yoshiya, Sakai Akinori
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2020年03月, 査読あり, 招待無し

Epstein-Barr virus-induced gene 3 commits human mesenchymal stem cells to differentiate into chondrocytes via endoplasmic reticulum stress sensor.
Zhang Tong, Yamagata Kaoru, Iwata Shigeru, Sonomoto Koshiro, Trimova Gulzhan, Nguyen Anh Phuong, Hao He, Shan Yu, Nguyen Mai-Phuong, Nakayamada Shingo, Tanaka Yoshiya
PloS one, 2022年12月, 査読あり, 招待無し

Spontaneous Differentiation of Human Mesenchymal Stem Cells on Poly-Lactic-Co-Glycolic Acid Nano-Fiber Scaffold.
Sonomoto Koshiro, Yamaoka Kunihiro, Kaneko Hiroaki, Yamagata Kaoru, Sakata Kei, Zhang Xiangmei, Kondo Masahiro, Zenke Yukichi, Sabanai Ken, Nakayamada Shingo, Sakai Akinori, Tanaka Yoshiya
PloS one, 2016年04月, 査読あり, 招待無し
筆頭著者

Association of peripheral CD8+ T cell activation with disease activity and treatment resistance in systemic lupus erythematosus.
Fujita Yuya, Nakayamada Shingo, Kubo Satoshi, Miyazaki Yusuke, Sonomoto Koshiro, Tanaka Hiroaki, Tanaka Yoshiya
RMD open, 2025年02月, 査読あり, 招待無し

Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus.
Ueno Masanobu, Iwata Shigeru, Yamagata Kaoru, Todoroki Yasuyuki, Sonomoto Koshiro, Nagayasu Atsushi, Miyagawa Ippei, Kubo Satoshi, Miyazaki Yusuke, Miyata Hiroko, Kanda Ryuichiro, Aritomi Takafumi, Nakayamada Shingo, Tanaka Yoshiya
RMD open, 2024年12月, 査読あり, 招待無し

Modifying T cell phenotypes using TYK2 inhibitor and its implications for the treatment of systemic lupus erythematosus.
Satoh-Kanda Yurie, Nakayamada Shingo, Kubo Satoshi, Yamagata Kaoru, Nawata Aya, Tanaka Hiroaki, Kosaka Shunpei, Kanda Ryuichiro, Yu Shan, Fujita Yuya, Sonomoto Koshiro, Tanaka Yoshiya
RMD open, 2024年06月, 査読あり, 招待無し

CT informs detection and treatment options in rheumatoid arthritis complicated by pulmonary non-tuberculous mycobacterial disease from the FIRST registry.
Funada Masashi, Miyazaki Yusuke, Nakayamada Shingo, Sonomoto Koshiro, Kubo Satoshi, Miyagawa Ippei, Tanaka Hiroaki, Tanaka Yoshiya
RMD open, 2024年06月, 査読あり, 招待無し

Biological/targeted synthetic DMARDs do not arrest bone loss in patients with rheumatoid arthritis: a multicenter prospective observational study.
Sonomoto Koshiro, Nakayamada Shingo, Fujino Yoshihisa, Miyata Hiroko, Kubo Satoshi, Fujita Yuya, Inoue Yoshino, Matsunaga Satsuki, Iwata Shigeru, Hanami Kentaro, Todoroki Yasuyuki, Yoshinari-Korekoda Hiroko, Kawabe Akio, Yamaguchi Ayako, Ueno Masanobu, Satoh-Kanda Yurie, Kanda Ryuichiro, Funada Masashi, Ohkubo Naoaki, Kusaka Katsuhide, Kosaka Shumpei, Nagayasu Atsushi, Fukuyo Shunsuke, Nawata Masao, Miyazaki Yusuke, Tokunaga Mikiko, Tanaka Kenichi, Okada Yosuke, Tanaka Yoshiya
Rheumatology (Oxford, England), 2023年11月, 査読あり, 招待無し
筆頭著者

Safety and efficacy of anifrolumab therapy in systemic lupus erythematosus in real-world clinical practice: LOOPS registry.
Miyazaki Yusuke, Funada Masashi, Nakayamada Shingo, Sonomoto Koshiro, Tanaka Hiroaki, Hanami Kentaro, Fukuyo Shunsuke, Kubo Satoshi, Yamaguchi Ayako, Miyagawa Ippei, Todoroki Yasuyuki, Ueno Masanobu, Tanaka Yoshiya
Rheumatology (Oxford, England), 2024年09月, 査読あり, 招待無し

An enhanced mitochondrial function through glutamine metabolism in plasmablast differentiation in systemic lupus erythematosus.
Sumikawa Maiko Hajime, Iwata Shigeru, Zhang Mingzeng, Miyata Hiroko, Ueno Masanobu, Todoroki Yasuyuki, Nagayasu Atsushi, Kanda Ryuichiro, Sonomoto Koshiro, Torimoto Keiichi, Lee Seunghyun, Nakayamada Shingo, Yamamoto Kazuo, Okada Yosuke, Tanaka Yoshiya
Rheumatology (Oxford, England), 2021年11月, 査読あり, 招待無し

T helper cells expressing fractalkine receptor and bearing T follicular helper 1-like cell functions in patients with IgG4-related disease.
Inoue Yoshino, Nakayamada Shingo, Kubo Satoshi, Yamagata Kaoru, Sonomoto Koshiro, Iwata Shigeru, Miyazaki Yusuke, Tanaka Yoshiya
Rheumatology (Oxford, England), 2021年12月, 指定なし, 指定なし

Reduced homovanillic acid, SDF-1α, and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus
Yuya Fujita, Shigeru Iwata, Shinsuke Hidese, Sayuri Ishiwata, Satoru Ide, Hiroaki Tanaka, Koshiro Sonomoto, Yusuke Miyazaki, Shingo Nakayamada, Atsuko Ikenouchi, Kotaro Hattori, Hiroshi Kunugi, Reiji Yoshimura, Yoshiya Tanaka
Rheumatology (Oxford, England), 2023年02月, 査読あり, 招待無し

Computed tomography for malignancy screening in patients with rheumatoid arthritis before initiation of disease modifying antirheumatic drug.
Miyata Hiroko, Sonomoto Koshiro, Fukuyo Shunsuke, Nakayamada Shingo, Nakano Kazuhisa, Iwata Shigeru, Miyazaki Yusuke, Kawabe Akio, Aoki Takatoshi, Tanaka Yoshiya
Rheumatology (Oxford, England), 2023年02月, 査読あり, 招待無し

TGF-β3 in differentiation and function of Tph-like cells and its relevance to disease activity in patients with systemic lupus erythematosus.
Shan Yu, Nakayamada Shingo, Nawata Aya, Yamagata Kaoru, Sonomoto Koshiro, Tanaka Hiroaki, Satoh-Kanda Yurie, Nguyen Mai-Phuong, Todoroki Yasuyuki, Nagayasu Atsushi, Ueno Masanobu, Kanda Ryuichiro, Fujita Yuya, Zhang Tong, Hao He, Zhou Jieqing, Ma Xiaoxue, Anan Junpei, Nguyen Anh Phuong, Tanaka Yoshiya
Rheumatology (Oxford, England), 2023年, 査読あり, 招待無し

T helper cells expressing fractalkine receptor and bearing T follicular helper 1-like cell functions in patients with IgG4-related disease.
Inoue Yoshino, Nakayamada Shingo, Kubo Satoshi, Yamagata Kaoru, Sonomoto Koshiro, Iwata Shigeru, Miyazaki Yusuke, Tanaka Yoshiya
Rheumatology (Oxford, England), 2022年08月, 査読あり, 招待無し

Efficacy and safety of belimumab during maintenance therapy in patients with systemic lupus erythematosus.
Miyazaki Yusuke, Nakayamada Shingo, Sonomoto Koshiro, Akio Kawabe, Inoue Yoshino, Okubo Naoaki, Iwata Shigeru, Hanami Kentaro, Tanaka Yoshiya
Rheumatology (Oxford, England), 2021年08月, 査読あり, 招待無し

mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors.
Zhang Mingzeng, Iwata Shigeru, Sonomoto Koshiro, Ueno Masanobu, Fujita Yuya, Anan Junpei, Miyazaki Yusuke, Ohkubo Naoaki, Sumikawa Maiko Hajime, Todoroki Yasuyuki, Miyata Hiroko, Nagayasu Atsushi, Kanda Ryuichiro, Trimova Gulzhan, Lee Seunghyun, Nakayamada Shingo, Sakata Kei, Tanaka Yoshiya
Rheumatology (Oxford, England), 2021年11月, 査読あり, 招待無し

Pathological role of activated mTOR in CXCR3+ memory B cells of rheumatoid arthritis.
Iwata Shigeru, Zhang Mingzeng, Hajime Maiko, Ohkubo Naoaki, Sonomoto Koshiro, Torimoto Keiichi, Kitanaga Yukihiro, Trimova Gulzhan, Todoroki Yasuyuki, Miyata Hiroko, Ueno Masanobu, Nagayasu Atsushi, Kanda Ryuichiro, Nakano Kazuhisa, Nakayamada Shingo, Sakata Kei, Tanaka Yoshiya
Rheumatology (Oxford, England), 2021年11月, 指定なし, 指定なし

Effects of tofacitinib on lymphocytes in rheumatoid arthritis: relation to efficacy and infectious adverse events.
Sonomoto Koshiro, Yamaoka Kunihiro, Kubo Satoshi, Hirata Shintaro, Fukuyo Shunsuke, Maeshima Keisuke, Suzuki Katsunori, Saito Kazuyoshi, Tanaka Yoshiya
Rheumatology (Oxford, England), 2014年05月, 指定なし, 指定なし
筆頭著者

Prophylaxis against pneumocystis pneumonia in rheumatoid arthritis patients treated with b/tsDMARDs: Insights from 3,787 cases in FIRST registry.
Sonomoto Koshiro, Tanaka Hiroaki, Nguyen Tuan Manh, Yoshinari Hiroko, Nakano Kazuhisa, Nakayamada Shingo, Tanaka Yoshiya
Rheumatology (Oxford, England), 2021年08月, 査読あり, 招待無し
筆頭著者

A Machine Learning Approach for Prediction of CDAI Remission with TNF Inhibitors: A Concept of Precision Medicine from the FIRST Registry.
Sonomoto Koshiro, Fujino Yoshihisa, Tanaka Hiroaki, Nagayasu Atsushi, Nakayamada Shingo, Tanaka Yoshiya
Rheumatology and therapy, 2024年03月, 査読あり, 招待無し
筆頭著者

Real-World Safety and Efficacy of Targeted Therapies in Rheumatoid Arthritis: A 5-Year, 5130-Case Follow-Up from FIRST Registry.
Sonomoto Koshiro, Nakayamada Shingo, Tanaka Hiroaki, Nagayasu Atsushi, Tanaka Yoshiya
Rheumatology and therapy, 2025年04月, 査読あり, 招待無し
筆頭著者

Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis.
Nagayasu Atsushi, Miyazaki Yusuke, Sonomoto Koshiro, Kubo Satoshi, Miyagawa Ippei, Yamaguchi Ayako, Tanaka Hiroaki, Todoroki Yasuyuki, Ueno Masanobu, Aritomi Takafumi, Fujita Yuya, Sakai Hidenori, Suzuki Katsunori, Nakayamada Shingo, Tanaka Yoshiya
Rheumatology and therapy, 2025年08月, 査読あり, 招待無し

Methotrexate, Tofacitinib, and Biologic Disease-Modifying Antirheumatic Drug Safety and Effectiveness Among Patients with Rheumatoid Arthritis in Japan: CorEvitas Registry Observational Study.
Tanaka Yoshiya, Kishimoto Mitsumasa, Sonomoto Koshiro, Amano Koichi, Harigai Masayoshi, Onofrei Alina, O'Brien Jacqueline, Margolin Zachary, Barr Christine, Mizuno Yasushi, Agarwal Ekta, Sugiyama Naonobu, Yamanaka Hisashi
Rheumatology and therapy, 2024年10月, 査読あり, 招待無し

Generation-Dependent Retention Rates and Reasons for Discontinuation of Molecular Targeted Therapies in Patients with Rheumatoid Arthritis: From FIRST Registry.
Kubo Satoshi, Miyazaki Yusuke, Todoroki Yasuyuki, Nagayasu Atsushi, Kanda Ryuichiro, Aritomi Takafumi, Matsunaga Satsuki, Ueno Masanobu, Miyagawa Ippei, Sonomoto Koshiro, Hanami Kentaro, Nakayamada Shingo, Tanaka Yoshiya
Rheumatology and therapy, 2023年10月, 査読あり, 招待無し

Discontinuation of etanercept in patients with rheumatoid arthritis who were in clinical remission.
Miyamura Tomoya, Sonomoto Koshiro, Nakamura Masataka, Horai Yoshiro, Takahama Soichiro, Ando Hitoshi, Minami Rumi, Yamamoto Masahiro, Suematsu Eiichi
Clinical rheumatology, 2010年01月, 指定なし, 指定なし

[An approach to bone and cartilage repair of rheumatoid arthritis by mesenchymal stem cells].
Sonomoto Koshiro, Yamaoka Kunihiro, Tanaka Yoshiya
Journal of UOEH, 2014年06月, 指定なし, 指定なし
筆頭著者

Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis.
Yukawa Sonosuke, Yamaoka Kunihiro, Sawamukai Norifumi, Shimajiri Shohei, Kubo Satoshi, Miyagawa Ippei, Sonomoto Koshiro, Saito Kazuyoshi, Tanaka Yoshiya
Modern rheumatology, 2013年11月, 指定なし, 指定なし

Influenza virus B-associated hemophagocytic syndrome and recurrent pericarditis in a patient with systemic lupus erythematosus.
Horai Yoshiro, Miyamura Tomoya, Takahama Soichiro, Sonomoto Koshiro, Nakamura Masataka, Ando Hitoshi, Minami Rumi, Yamamoto Masahiro, Suematsu Eiichi
Modern rheumatology, 2010年04月, 指定なし, 指定なし

[Case report; a case of acetaminophen-induced hypersensitivity vasculitis].
Shibahara Tomoya, Moriwaki Atsushi, Sonomoto Koshiro, Katahira Katsuyuki, Enokizu Aimi, Kato Kaori, Shimokama Tatsuro, Kawakami Satoru, Imanaga Tomotoshi
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014年01月, 指定なし, 指定なし

Relevance of involvement of tofacitinib in T cell subsets to clinical courses and adverse events in patients with rheumatoid arthritis.
Sonomoto Koshiro, Tanaka Yohisya
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2015年06月, 指定なし, 指定なし
筆頭著者

[Mesenchymal stem cells for the treatment and repair of inflammatory arthritis].
Tanaka Yoshiya, Sonomoto Koshiro, Kondo Masahiro, Oshita Koichi, Zhang Xiang-Mei, Fukuyo Shunsuke, Yamaoka Kunihiro
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2015年02月, 指定なし, 指定なし

[Anti-rheumatic effect of JAK-inhibitors].
Yamaoka Kunihiro, Maeshima Keisuke, Kubo Satoshi, Sonomoto Koshiro, Tanaka Yoshiya
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2012年02月, 指定なし, 指定なし

[Microscopic polyangiitis in a patient on hemodialysis : a case report].
Horai Yoshiro, Miyamura Tomoya, Takahama Soichiro, Sonomoto Koshiro, Nakamura Masataka, Ando Hitoshi, Minami Rumi, Yamamoto Masahiro, Suematsu Eiichi
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年12月, 指定なし, 指定なし

[A clinical study of five cases demonstrating relapsing polychondritis].
Minami Rumi, Miyamura Tomoya, Nakamura Masataka, Sonomoto Koshiro, Horai Yoshiro, Takahama Soichiro, Ando Hitoshi, Yamamoto Masahiro, Suematsu Eiichi
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年08月, 指定なし, 指定なし

[A case of systemic lupus erythematosus complicated with autoimmune hepatitis and thrombotic thrombocytic purpura].
Sonomoto Koshiro, Miyamura Tomoya, Watanabe Hideyuki, Takahama Soichiro, Nakamura Masataka, Ando Hitoshi, Minami Rumi, Yamamoto Masahiro, Suematsu Eiichi
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年04月, 指定なし, 指定なし
筆頭著者

[Diagnostic utility of anti-cyclic citrullinated peptide antibody in early rheumatoid arthritis].
Miyamura Tomoya, Watanabe Hideyuki, Takahama Soichiro, Sonomoto Koshiro, Nakamura Masataka, Ando Hitosi, Minami Rumi, Yamamoto Masahiro, Suematsu Eiichi
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009年04月, 指定なし, 指定なし

[Thrombotic thrombocytopenic purpura in patients with systemic lupus erythematosus].
Miyamura Tomoya, Watanabe Hideyuki, Takahama Soichiro, Sonomoto Koshiro, Nakamura Masataka, Ando Hitosi, Minami Rumi, Yamamoto Masahiro, Suematsu Eiichi
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2008年06月, 指定なし, 指定なし

[A case of polyarteritis nodosa successfully treated by rituximab].
Sonomoto Koshiro, Miyamura Tomaya, Watanabe Hideyuki, Takahama Soichiro, Nakamura Masataka, Ando Hitoshi, Minami Rumi, Yamamoto Masahiro, Saito Tomoko, Imayama Shuhei, Hosokawa Chisato, Suematsu Eiichi
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2008年04月, 指定なし, 指定なし
筆頭著者

Local delivery of mesenchymal stem cells with poly-lactic-co-glycolic acid nano-fiber scaffold suppress arthritis in rats.
Zhang Xiangmei, Yamaoka Kunihiro, Sonomoto Koshiro, Kaneko Hiroaki, Satake Makoto, Yamamoto Yuka, Kondo Masahiro, Zhao Jidong, Miyagawa Ippei, Yamagata Kaoru, Fukuyo Shunsuke, Okada Yosuke, Tanaka Yoshiya
PloS one, 2014年12月, 指定なし, 指定なし

IL-17 inhibits chondrogenic differentiation of human mesenchymal stem cells.
Kondo Masahiro, Yamaoka Kunihiro, Sonomoto Koshiro, Fukuyo Shunsuke, Oshita Koichi, Okada Yosuke, Tanaka Yoshiya
PloS one, 2013年11月, 指定なし, 指定なし

IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent.
Fukuyo Shunsuke, Yamaoka Kunihiro, Sonomoto Koshiro, Oshita Koichi, Okada Yosuke, Saito Kazuyoshi, Yoshida Yasuhiro, Kanazawa Tamotsu, Minami Yasuhiro, Tanaka Yoshiya
Rheumatology (Oxford, England), 2014年07月, 指定なし, 指定なし