Clinical dilemma of mood stabilizer augmentation in treatment‐resistant schizophrenia with residual phase: A case report of valproate‐associated hypoglycemia and cytopenia, and subsequent lithium response
Yoshiki Kasagi; Naomichi Okamoto; Reiji Yoshimura
Psychiatry and Clinical Neurosciences Reports, Jun. 2026, Reviewed
Corresponding

Increase of the AMPA-evoked response of pyramidal neurons in the rat medial prefrontal cortex following acute administration of ketamine and S-ketamine, but not R-ketamine.
El Mansari M; Okamoto N; Blier P
The international journal of neuropsychopharmacology, May 2026

Risk Factors in Japanese Drug Overdose Patients: Identifying Their Associations With Suicide Risk
Naomichi Okamoto; Atsuko Ikenouchi; Enkhmurun Chibaatar; Keita Watanabe; Ryohei Igata; Issei Seki; Reiji Yoshimura
OMEGA - Journal of Death and Dying, Sep. 2025, Reviewed
Lead, Corresponding

Serum Lipidome Change in Japanese Patients with Major Depressive Disorder: A Real-World Exploratory Study
Naomichi Okamoto; Rintaro Fujii; Enkhmurun Chibaatar; Chihiro Iino; Atsuko Ikenouchi; Reiji Yoshimura
Neuropsychiatric Disease and Treatment, Aug. 2025, Reviewed
Lead, Corresponding

Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia
Tomoya Natsuyama; Enkhmurun Chibaatar; Yuko Shibata; Naomichi Okamoto; John Noel Cruz Victorino; Atsuko Ikenouchi; Tomohiro Shibata; Reiji Yoshimura
Neuropsychiatric Disease and Treatment, Apr. 2025, Reviewed

Evaluating Apelin as a Potential Biomarker in Major Depressive Disorder: Its Correlation with Clinical Symptomatology
Enkhmurun Chibaatar; Rintarou Fujii; Atsuko Ikenouchi; Naomichi Okamoto; Tomoya Natsuyama; Gaku Hayasaki; Takahiro Shinkai; Reiji Yoshimura
International Journal of Molecular Sciences, Dec. 2024

Low‐dose lamotrigine induces Pisa syndrome in a patient with probable corticobasal degeneration despite previous use
Naomichi Okamoto; Takahiro Sakakibara; Nagiho Tsukada; Enkhmurun Chibaatar; Gaku Hayasaki; Yuki Konishi; Atsuko Ikenouchi; Reiji Yoshimura
Psychogeriatrics, Nov. 2024, Reviewed
Lead, Corresponding

Effect modification of tumor necrosis factor-α on the kynurenine and serotonin pathways in major depressive disorder on type 2 diabetes mellitus
Naomichi Okamoto; Takashi Hoshikawa; Yuichi Honma; Enkhmurun Chibaatar; Atsuko Ikenouchi; Masaru Harada; Reiji Yoshimura
European Archives of Psychiatry and Clinical Neuroscience, Oct. 2024, Reviewed
Lead, Corresponding

Human immunodeficiency virus-related neurocognitive disorder with hallucinations and delusions: A case report
Junpei Igata; Naomichi Okamoto; Hirofumi Tesen; Maya Akiyama; Satoru Ide; Atsuko Ikenouchi; Reiji Yoshimura
Psychiatry Research Case Reports, Jun. 2024
Corresponding

Oromandibular Dystonia After Low-Dose Olanzapine Treatment in a Patient With Marchiafava-Bignami Disease With Demyelinating Lesions in the Corpus Callosum: A Case Report
Nagiho Tsukada; Naomichi Okamoto; Yuki Konishi; Atsuko Ikenouchi; Reiji Yoshimura
Cureus, Jan. 2024
Corresponding

A case of folate deficiency showing behavioural variant of frontotemporal dementia‐like symptoms
Arisa Fujii; Atsuko Ikenouchi; Naomichi Okamoto; Rintaro Fujii; Satoru Ide; Reiji Yoshimura
Psychogeriatrics, Dec. 2023

A case of 10-year retrograde amnesia, cognitive dysfunction, and hippocampal atrophy after limbic encephalitis associated with rickettsiosis
Naomichi Okamoto; Atsuko Ikenouchi; Shoichi Shimizu; Satoru Ide; Enkhmurun Chibaatar; Reiji Yoshimura
Psychiatry Research Case Reports, Dec. 2023
Lead, Corresponding

Serum Extracellular Vesicle-Derived hsa-miR-2277-3p and hsa-miR-6813-3p Are Potential Biomarkers for Major Depression: A Preliminary Study
Issei Seki; Hiroto Izumi; Naomichi Okamoto; Atsuko Ikenouchi; Yasuo Morimoto; Seichi Horie; Reiji Yoshimura
International Journal of Molecular Sciences, Sep. 2023

Auditory hallucinations of Buddhist chanting as an initial symptom of mild cognitive impairment with Lewy bodies
Naomichi Okamoto; Atsuko Ikenouchi; Tatsuro Hirashima; Hirofumi Tesen; Satoru Ide; Reiji Yoshimura
Psychogeriatrics, Jul. 2023, Reviewed
Lead, Corresponding

Acute pancreatitis during valproic acid administration in a patient with vascular dementia, epileptic seizures, and psychiatric symptoms: a case report
Mako Yanaga; Naomichi Okamoto; Reia Hashimoto; Ryohei Igata; Yuki Konishi; Atsuko Ikenouchi; Naoki Isomoto; Takahiro Shinkai; Masaru Harada; Reiji Yoshimura
Journal of Medical Case Reports, May 2023, Reviewed
Corresponding

Prolonged delirium caused by lithium poisoning in an endometrial cancer patient at advanced stage: A case report.
Natsuyama T; Okamoto N; Akaji H; Hoshino K; Ikenouchi A; Reiji
Clinical case reports, Mar. 2023

A case of exploding head syndrome preceding the onset of mild cognitive impairment with Lewy bodies
Shogo Kitagawa; Naomichi Okamoto; Atsuko Ikenouchi; Ryohei Igata; Reia Hashimoto; Yuki Konishi; Hirofumi Tesen; Reiji Yoshimura
Psychogeriatrics, Mar. 2023
Corresponding

The Serum Brain-Derived Neurotrophic Factor Increases in Serotonin Reuptake Inhibitor Responders Patients with First-Episode, Drug-Naïve Major Depression
Reiji Yoshimura; Naomichi Okamoto; Enkmurun Chibaatar; Tomoya Natsuyama; Atsuko Ikenouchi
Biomedicines, Feb. 2023

Comparison of Serum Metabolomics Pathways and Patterns between Patients with Major Depressive Disorder with and without Type 2 Diabetes Mellitus: An Exploratory Study
Naomichi Okamoto; Takashi Hoshikawa; Atsuko Ikenouchi; Tomoya Natsuyama; Rintaro Fujii; Ryohei Igata; Hirofumi Tesen; Yuki Konishi; Yuichi Honma; Masaru Harada; Reiji Yoshimura
Journal of Integrative Neuroscience, Jan. 2023, Reviewed
Lead

Serum brain-derived neurotrophic factor levels in depression with and without melancholy and in healthy participants
Reiji Yoshimura; Naomichi Okamoto; Atsuko Ikenouchi
The European Journal of Psychiatry, Jan. 2023

Mania after long‐term treatment with daily 10 mg prednisolone
Rintaro Fujii; Yuki Konishi; Ryutaro Furusawa; Naomichi Okamoto; Reiji Yoshimura
Psychiatry and Clinical Neurosciences Reports, Dec. 2022

Isolated adrenocorticotropic hormone deficiency accompanied by impaired cognitive function: A case report
Atsuko Ikenouchi; Issei Seki; Naomichi Okamoto; Yuki Konishi; Reiji Yoshimura
Psychiatry Research Case Reports, Dec. 2022

Comparison of plasma catecholamine metabolites in melancholic and non-melancholic depression
Reiji Yoshimura; Naomichi Okamoto; Atsuko Ikenouchi
Psychiatry Research Communications, Sep. 2022

Increased Stimulation Intensity Helped to Cope with Prolonged Seizures During the Next Round of Modified Electroconvulsive Therapy: A Case Report
Tetsuya Katsumura; Naomichi Okamoto; Hirofumi Tesen; Ryohei Igata; Atsuko Ikenouchi; Reiji Yoshimura
International Medical Case Reports Journal, Jul. 2022
Corresponding

The Molecular Mechanism of Exercise for Treatment of Patients with Major Depression: A Preliminary Report on the Dynamics of Metabolites of Nitric Oxide and Catecholamines
Atsuko Ikenouchi; Naomichi Okamoto; Ryohei Igata; Tomoya Natsuyama; Reiji Yoshimura
Journal of Integrative Neuroscience, Jun. 2022

Volume of Amygdala Subregions and Plasma Levels of Brain-Derived Neurotrophic Factor and Cortisol in Patients with s/s Genotype of Serotonin Transporter Gene Polymorphism of First-Episode and Drug-Naive Major Depressive Disorder: An Exploratory Study
Naomichi Okamoto; Keita Watanabe; Hirofumi Tesen; Atsuko Ikenouchi; Ryohei Igata; Yuki Konishi; Tomoya Natsuyama; Rintaro Fujii; Shingo Kakeda; Taro Kishi; Nakao Iwata; Reiji Yoshimura
Neurology International, Apr. 2022, Reviewed
Lead

Associations of Serum Cytokines, Growth Factors, and High-Sensitivity C-Reactive Protein Levels in Patients with Major Depression with and without Type 2 Diabetes Mellitus: An Explanatory Investigation.
Naomichi Okamoto
Neuropsychiatric disease and treatment, Feb. 2022

L-Arginine-Nitric Oxide Pathway and Neural Networks in Major Depression.
Naomichi Okamoto
Psychiatria Danubina, Jan. 2022

A Metabolomics Study of Serum in Hospitalized Patients With Chronic Schizophrenia
Naomichi Okamoto; Atsuko Ikenouchi; Keita Watanabe; Ryohei Igata; Rintaro Fujii; Reiji Yoshimura
Frontiers in Psychiatry, Dec. 2021, Reviewed
Lead

A Young Japanese Patient with Spinocerebellar Ataxia Type 3 Presenting Depressive State with Cenesthopathy and Delusion: a Case Report
Naomichi Okamoto
The Cerebellum, Oct. 2021
Lead

Associations Between the Kynurenine Pathway, Proinflammatory Cytokines, and Brain-Derived Neurotrophic Factor in Hospitalized Patients With Chronic Schizophrenia: A Preliminary Study.
Naomichi Okamoto
Frontiers in psychiatry, Jul. 2021

Cerebral Amyloid Angiopathy With a Hypomanic Episode Treated With Valproic Acid.
Naomichi Okamoto
Cureus, Jul. 2021

Prisoner's dilemma game in recovered schizophrenia patients, compared with healthy controls: Preliminary findings.
Naomichi Okamoto
Schizophrenia research, Jul. 2021

Vortioxetine Improved Depressive State In Parkinson's Disease.
Naomichi Okamoto
Cureus, Jun. 2021

Colchicine-Resistant Familial Mediterranean Fever With Depressive State Successfully Treated With Escitalopram.
Naomichi Okamoto
Cureus, May 2021

Associations between plasma levels of C-reactive protein and catecholamine metabolites in patients with major depression.
Naomichi Okamoto; Takashi Hoshikawa; Reiji Yoshimura
Therapeutic advances in psychopharmacology, May 2021, Reviewed
Lead

A Case of Major Depression with Burning Mouth Syndrome and Tinnitus Successfully Treated with Vortioxetine.
Naomichi Okamoto
International medical case reports journal, Apr. 2021

A Low Clozapine Dose Improved Refractory Tardive Dystonia without Exacerbating Psychiatric Symptoms: A Case Report.
Naomichi Okamoto
International medical case reports journal, Apr. 2021
Lead

Major depression with musical obsession treated with vortioxetine: a case report.
Naomichi Okamoto
Annals of general psychiatry, Mar. 2021

Association Between Serum Insulin-Like Growth Factor 1 Levels and the Clinical Symptoms of Chronic Schizophrenia: Preliminary Findings.
Naomichi Okamoto
Frontiers in psychiatry, Mar. 2021, Reviewed
Lead

A male case of frontotemporal lobar degeneration with behavioural and psychiatric symptoms responding to a low dose of escitalopram.
Naomichi Okamoto
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, Feb. 2021

Volume of Amygdala Subregions and Clinical Manifestations in Patients With First-Episode, Drug-Naïve Major Depression.
Naomichi Okamoto
Frontiers in human neuroscience, Jan. 2021

Association of Serum Kynurenine Levels and Neural Networks in Patients with First-Episode, Drug-Naïve Major Depression: A Source-Based Morphometry Study.
Naomichi Okamoto
Neuropsychiatric disease and treatment, Oct. 2020, Reviewed
Lead

A Case of Major Depression Comorbid with Social Phobia Treated Successfully with Vortioxetine.
Reiji Yoshimura; Naomichi Okamoto
Psychiatria Danubina, Sep. 2020

椎茸丸飲みにより食餌性イレウスを来した1例
岡本直通、石崎宏美、　廣延綾子、　土田恭幸、　西原礼介、　新原健介、
Journal of Radiology, Feb. 2018, Null, Null
Lead

強迫症を合併した重度うつ病の1例
岡本直通,阿竹聖和,斎藤恒祐,吉野幸司,定村佳,藤井倫太郎,吉村玲児,
九州神経精神医学, Apr. 2018, Null, Null
Lead

【血液浄化療法-持続的腎代替療法(CRRT)を中心に-】 エンドトキシン吸着カラム(PMX-DHP)は有用か?
真弓 俊彦, 首藤 瑠里, 椎野 明日実, 舛本 直哉, 岡本 直通, 佐藤 直人, 手嶋 悠人, 草永 真志, 秋本 倫太郎, 宮川 一平, 花石 源太郎, 弓指 恵一, 大坪 広樹
日本外科感染症学会雑誌, Jun. 2018, Reviewed, Null

救急外来の自殺企図患者評価におけるSAD PERSONSスケールの有用性
岡本 直通, 宮川 一平, 濱田 信亮, 宮川 俊, 椎木 麻姫子, 成田 正雄, 石川 成人, 草永 真志, 吉村 玲児, 真弓 俊彦
日本臨床救急医学会雑誌, Aug. 2020, Reviewed, No invitation
Lead, Corresponding

心臓手術患者における退院後の睡眠導入薬に対する依存
岡本直通,櫻谷正明,吉田研一,河村夏生,筒井徹,吉廣尚大,
日本集中治療医学会, Feb. 2017, Null, Null
Lead

【重症急性膵炎とその合併症に対するマネジメント】 重症急性膵炎の病態と重症化の機序
真弓 俊彦, 首藤 瑠里, 椎野 明日実, 舛本 直哉, 岡本 直通, 佐藤 直人, 手嶋 悠人, 草永 真志, 秋本 倫太郎, 宮川 一平, 花石 源太郎, 弓指 恵一, 大坪 広樹
消化器・肝臓内科, Jun. 2018, Not reviewed, No invitation

椎茸丸飲みにて食餌性イレウスをきたした1例
岡本 直通, 石崎 宏美, 廣延 綾子, 土田 恭幸, 西原 礼介, 吉田 研一, 中村 浩之, 中光 篤志
臨床放射線, May 2017, Not reviewed, Invited
Lead

臨床に役立つ　基礎薬理学の用語解説_x000D_ 第１７回　キヌレニン経路
岡本直通
臨床精神薬理, Mar. 2021, Null, Null
Lead, Corresponding

Factors Influencing Continuing Employment Among Patients With Mood Disorders
Hirofumi Tesen, Tomomi Matsumoto, Maiko Umezu, Kenta Ide, Koji Yoshino, Ryohei Igata, Yuki Konishi, Naomichi Okamoto, Atsuko Ikenouchi, Yoshihisa Fujino, and Reiji Yoshimura
ASEAN Journal of Psychiatry, Aug. 2022, Reviewed, No invitation

SERUM LEVELS OF INTERLEUKIN-6 ,BRAIN-DERIVED NEUROTROPHIC FACTOR AND RETURN TO WORK IN PATIENTS WITH MAJOR DEPRESSION:PRELIMINARY STUDY
Reiji Yoshimura, Naomichi Okamoto, Atsuko Ikenouchi
ASEAN Journal of Psychiatry, Oct. 2021, Reviewed, No invitation

Reproducibility of the Efficacy of Escitalopram in Patients with Major Depression Who Had Previously Remitted with Escitalopram.
Yoshimura Reiji, Okamoto Naomichi, Igata Ryohei, Ikenouchi Atsuko
Alpha psychiatry, Jan. 2022, Reviewed, No invitation

Major depression with musical obsession treated with vortioxetine: a case report.
Yoshimura Reiji, Okamoto Naomichi, Konishi Yuki, Ikenouchi Atsuko
Annals of general psychiatry, Mar. 2021, Reviewed, No invitation

Influence of antidepressants on plasma levels of nitric oxide metabolites in patients with major depressive disorder - RETRACTION.
Ikenouchi Atsuko, Okamoto Naomichi, Konno Yusuke, Fujii Rintaro, Fujino Yoshihisa, Yoshimura Reiji
BJPsych open, Mar. 2022, Reviewed, No invitation

Influence of antidepressants on plasma levels of nitric oxide metabolites in patients with major depressive disorder.
Ikenouchi Atsuko, Okamoto Naomichi, Konno Yusuke, Fujii Rintaro, Fujino Yoshihisa, Yoshimura Reiji
BJPsych open, Dec. 2021, Reviewed, No invitation

Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report.
Kijima Reoto, Tesen Hirofumi, Igata Ryohei, Okamoto Naomichi, Yoshimura Reiji
BMC psychiatry, Oct. 2023, Reviewed, No invitation

The Serum Brain-Derived Neurotrophic Factor Increases in Serotonin Reuptake Inhibitor Responders Patients with First-Episode, Drug-Naïve Major Depression.
Yoshimura Reiji, Okamoto Naomichi, Chibaatar Enkmurun, Natsuyama Tomoya, Ikenouchi Atsuko
Biomedicines, Feb. 2023, Reviewed, No invitation

Association between salivary mature brain-derived neurotrophic factor and psychological distress in healthcare workers.
Ikenouchi Atsuko, Okamoto Naomichi, Hamada Shinsuke, Chibaatar Enkhmurun, Fujii Rintaro, Konishi Yuki, Igata Ryohei, Tesen Hirofumi, Yoshimura Reiji
Brain and behavior, Oct. 2023, Reviewed, No invitation

Disturbed hippocampal intra-network in first-episode of drug-naïve major depressive disorder.
Watanabe Keita, Okamoto Naomichi, Ueda Issei, Tesen Hirofumi, Fujii Rintaro, Ikenouchi Atsuko, Yoshimura Reiji, Kakeda Shingo
Brain communications, Jan. 2023, Reviewed, No invitation

Panic Disorder Induced by the Coronavirus Disease Pandemic in a Patient with Organic Mood Disorder Successfully Treated with Vortioxetine.
Yoshimura Reiji, Okamoto Naomichi, Konishi Yuki, Ikenouchi Atsuko
Case reports in psychiatry, Oct. 2020, Not reviewed, No invitation

A Young Japanese Patient with Spinocerebellar Ataxia Type 3 Presenting Depressive State with Cenesthopathy and Delusion: a Case Report.
Okamoto Naomichi, Ikenouchi Atsuko, Ide Satoru, Hashimoto Yu, Yoshimura Reiji
Cerebellum (London, England), Oct. 2021, Reviewed, No invitation
Lead

Plasma levels of paroxetine are not associated with the increase of serum levels of brain-derived neurotrophic factor in major depression
Reiji Yoshimura, Naomichi Okamoto, Yuki Konishi, Atsuko Ikenouchi
Clinical Neuropsychopharmacology and Therapeutics, Jul. 2020, Reviewed, No invitation

Prolonged delirium caused by lithium poisoning in an endometrial cancer patient at advanced stage: A case report.
Natsuyama Tomoya, Okamoto Naomichi, Akaji Haruka, Hoshino Kaori, Ikenouchi Atsuko, Yoshimura Reiji
Clinical case reports, Mar. 2023, Reviewed, No invitation

Choosing Appropriate Nutritional Therapy for Patients With Anorexia Nervosa Exhibiting Liver Dysfunction: A Case Report.
Tsutsumi Motoharu, Okamoto Naomichi, Tesen Hirofumi, Kijima Reoto, Yoshimura Reiji
Cureus, Feb. 2024, Reviewed, No invitation

Oromandibular Dystonia After Low-Dose Olanzapine Treatment in a Patient With Marchiafava-Bignami Disease With Demyelinating Lesions in the Corpus Callosum: A Case Report.
Tsukada Nagiho, Okamoto Naomichi, Konishi Yuki, Ikenouchi Atsuko, Yoshimura Reiji
Cureus, Jan. 2024, Null, No invitation
Corresponding

Cerebral Amyloid Angiopathy With a Hypomanic Episode Treated With Valproic Acid.
Okamoto Naomichi, Ikenouchi Atsuko, Seki Issei, Hirano Natsumi, Yoshimura Reiji
Cureus, Jul. 2021, Reviewed, No invitation
Lead

Vortioxetine Improved Depressive State In Parkinson's Disease.
Yoshimura Reiji, Ikenouchi Atsuko, Okamoto Naomichi, Konishi Yuki
Cureus, Jun. 2021, Reviewed, No invitation

Colchicine-Resistant Familial Mediterranean Fever With Depressive State Successfully Treated With Escitalopram.
Toshida Masamitsu, Konishi Yuki, Ikenouchi Atsuko, Okamoto Naomichi, Yoshimura Reiji
Cureus, May 2021, Reviewed, No invitation

Serum levels of catecholamine metabolites and return to work in patients with major depression: preliminary study.
Yoshimura R, Okamoto N, Konishi Y, Ikenouchi A
The European Journal of Psychiatry, Aug. 2021, Reviewed, No invitation

Effect modification of tumor necrosis factor-α on the kynurenine and serotonin pathways in major depressive disorder on type 2 diabetes mellitus.
Okamoto Naomichi, Hoshikawa Takashi, Honma Yuichi, Chibaatar Enkhmurun, Ikenouchi Atsuko, Harada Masaru, Yoshimura Reiji
European archives of psychiatry and clinical neuroscience, Nov. 2023, Reviewed, No invitation
Lead, Corresponding

Effect of the personality traits of healthy Japanese workers on depressive symptoms and social adaptation, and on the achievement rate of exercise therapy to prevent major depression
Atsuko Ikenouchi, Naomichi Okamoto, Tomomi Matsumoto and Reiji Yoshimura
Frontiers in Psychology, Jun. 2023, Reviewed, No invitation

Volume of Amygdala Subregions and Clinical Manifestations in Patients With First-Episode, Drug-Naïve Major Depression.
Tesen Hirofumi, Watanabe Keita, Okamoto Naomichi, Ikenouchi Atsuko, Igata Ryohei, Konishi Yuki, Kakeda Shingo, Yoshimura Reiji
Frontiers in human neuroscience, Jan. 2022, Reviewed, No invitation

Hippocampal Volume and Plasma Brain-Derived Neurotrophic Factor Levels in Patients With Depression and Healthy Controls.
Fujii Rintaro, Watanabe Keita, Okamoto Naomichi, Natsuyama Tomoya, Tesen Hirofumi, Igata Ryohei, Konishi Yuki, Ikenouchi Atsuko, Kakeda Shingo, Yoshimura Reiji
Frontiers in molecular neuroscience, May 2022, Reviewed, No invitation

Fronto-striato network function is reduced in major depressive disorder.
Kijima Reoto, Watanabe Keita, Okamoto Naomichi, Ikenouchi Atsuko, Tesen Hirofumi, Kakeda Shingo, Yoshimura Reiji
Frontiers in psychiatry, Mar. 2024, Reviewed, No invitation

Volumetric assessment of individual thalamic nuclei in patients with drug-naïve, first-episode major depressive disorder.
Chibaatar Enkhmurun, Watanabe Keita, Okamoto Naomichi, Orkhonselenge Nasanbadrakh, Natsuyama Tomoya, Hayakawa Gaku, Ikenouchi Atsuko, Kakeda Shingo, Yoshimura Reiji
Frontiers in psychiatry, Mar. 2023, Reviewed, No invitation

Gyrification patterns in first-episode, drug-naïve major depression: Associations with plasma levels of brain-derived neurotrophic factor and psychiatric symptoms.
Natsuyama Tomoya, Okamoto Naomichi, Watanabe Keita, Chibaatar Enkhmurun, Tesen Hirofumi, Hayasaki Gaku, Ikenouchi Atsuko, Kakeda Shingo, Yoshimura Reiji
Frontiers in psychiatry, Jan. 2023, Reviewed, No invitation

A Metabolomics Study of Serum in Hospitalized Patients With Chronic Schizophrenia.
Okamoto Naomichi, Ikenouchi Atsuko, Watanabe Keita, Igata Ryohei, Fujii Rintaro, Yoshimura Reiji
Frontiers in psychiatry, Dec. 2021, Reviewed, No invitation
Lead

Associations Between the Kynurenine Pathway, Proinflammatory Cytokines, and Brain-Derived Neurotrophic Factor in Hospitalized Patients With Chronic Schizophrenia: A Preliminary Study.
Okamoto Naomichi, Natsuyama Tomoya, Igata Ryohei, Konishi Yuki, Tesen Hirofumi, Ikenouchi Atsuko, Yoshimura Reiji
Frontiers in psychiatry, Jul. 2021, Reviewed, Invited
Lead

Association Between Serum Insulin-Like Growth Factor 1 Levels and the Clinical Symptoms of Chronic Schizophrenia: Preliminary Findings.
Okamoto Naomichi, Yoshino Koji, Kitagawa Shogo, Fujii Rintaro, Hamada Shinsuke, Ikenouchi Atsuko, Konishi Yuki, Ueda Nobuhisa, Eto Yoshinori, Tsutsumi Yasunari, Yoshimura Reiji
Frontiers in psychiatry, Mar. 2021, Reviewed, No invitation
Lead

Corrigendum: Estimation of subjective quality of life in schizophrenic patients using speech features.
Shibata Yuko, Victorino John Noel, Natsuyama Tomoya, Okamoto Naomichi, Yoshimura Reiji, Shibata Tomohiro
Frontiers in rehabilitation sciences, Jun. 2023, Reviewed, No invitation

Estimation of subjective quality of life in schizophrenic patients using speech features.
Shibata Yuko, Victorino John Noel, Natsuyama Tomoya, Okamoto Naomichi, Yoshimura Reiji, Shibata Tomohiro
Frontiers in rehabilitation sciences, Mar. 2023, Reviewed, No invitation

Evaluating Apelin as a Potential Biomarker in Major Depressive Disorder: Its Correlation with Clinical Symptomatology.
Chibaatar Enkhmurun, Fujii Rintarou, Ikenouchi Atsuko, Okamoto Naomichi, Natsuyama Tomoya, Hayasaki Gaku, Shinkai Takahiro, Yoshimura Reiji
International journal of molecular sciences, Dec. 2024, Reviewed, No invitation

Serum Extracellular Vesicle-Derived hsa-miR-2277-3p and hsa-miR-6813-3p Are Potential Biomarkers for Major Depression: A Preliminary Study.
Seki Issei, Izumi Hiroto, Okamoto Naomichi, Ikenouchi Atsuko, Morimoto Yasuo, Horie Seichi, Yoshimura Reiji
International journal of molecular sciences, Sep. 2023, Reviewed, No invitation

Increased Stimulation Intensity Helped to Cope with Prolonged Seizures During the Next Round of Modified Electroconvulsive Therapy: A Case Report.
Katsumura Tetsuya, Okamoto Naomichi, Tesen Hirofumi, Igata Ryohei, Ikenouchi Atsuko, Yoshimura Reiji
International medical case reports journal, Jul. 2022, Reviewed, No invitation
Corresponding

A Case of Major Depression with Burning Mouth Syndrome and Tinnitus Successfully Treated with Vortioxetine.
Yoshimura Reiji, Ikenouchi Atsuko, Okamoto Naomichi, Konishi Yuki
International medical case reports journal, Apr. 2021, Reviewed, No invitation

A Low Clozapine Dose Improved Refractory Tardive Dystonia without Exacerbating Psychiatric Symptoms: A Case Report.
Okamoto Naomichi, Konishi Yuki, Tesen Hirofumi, Ikenouchi Atsuko, Yoshimura Reiji
International medical case reports journal, Apr. 2021, Reviewed, No invitation
Lead

Acute pancreatitis during valproic acid administration in a patient with vascular dementia, epileptic seizures, and psychiatric symptoms: a case report
Mako Yanaga, Naomichi Okamoto, Reia Hashimoto, Ryohei Igata, Yuki Konishi, Atsuko Ikenouchi, Naoki Isomoto, Takahiro Shinkai, Masaru Harada, Reiji Yoshimura
Journal of Medical Case Reports, May 2023, Reviewed, No invitation
Corresponding

Protocol for a Survey on the Impact of Caring for a Relative With Dementia on Caregivers' Health and Work Functioning.
Ikenouchi Atsuko, Fujino Yoshihisa, Matsumoto Tomomi, Okamoto Naomichi, Hamada Shinsuke, Kitagawa Shogo, Maruyama Shunya, Konishi Yuki, Eguchi Hisashi, Yoshimura Reiji
Journal of UOEH, Mar. 2025, Reviewed, No invitation

Volume enlargement of the choroid plexus and brain ventricles in drug-naïve, first-episode major depressive disorder.
Hayasaki Gaku, Chibaatar Enkmurun, Watanabe Keita, Okamoto Naomichi, Quinn Patrick M, Ikenouchi Atsuko, Shinkai Takahiro, Kakeda Shingo, Yoshimura Reiji
Journal of affective disorders, Mar. 2024, Reviewed, No invitation

Triple network connectivity changes in patients with major depressive disorder versus healthy controls via structural network imaging after electroconvulsive therapy treatment
Enkmurun Chibaata, Keita Watanab, Patrick M Quin, Naomichi Okamot, Takahiro Shinkai, Tomoya Natsuyama, Gaku Hayasaki, Atsuko Ikenouchi, Shingo Kakeda, Reiji Yoshimura
Journal of affective disorders, Nov. 2023, Reviewed, No invitation

Comparison of Serum Metabolomics Pathways and Patterns between Patients with Major Depressive Disorder with and without Type 2 Diabetes Mellitus: An Exploratory Study.
Okamoto Naomichi, Hoshikawa Takashi, Ikenouchi Atsuko, Natsuyama Tomoya, Fujii Rintaro, Igata Ryohei, Tesen Hirofumi, Konishi Yuki, Honma Yuichi, Harada Masaru, Yoshimura Reiji
Journal of integrative neuroscience, Jan. 2023, Reviewed, No invitation
Lead

The Molecular Mechanism of Exercise for Treatment of Patients with Major Depression: A Preliminary Report on the Dynamics of Metabolites of Nitric Oxide and Catecholamines.
Ikenouchi Atsuko, Okamoto Naomichi, Igata Ryohei, Natsuyama Tomoya, Yoshimura Reiji
Journal of integrative neuroscience, Jun. 2022, Reviewed, No invitation

Volume of Amygdala Subregions and Plasma Levels of Brain-Derived Neurotrophic Factor and Cortisol in Patients with s/s Genotype of Serotonin Transporter Gene Polymorphism of First-Episode and Drug-Naive Major Depressive Disorder: An Exploratory Study.
Okamoto Naomichi, Watanabe Keita, Tesen Hirofumi, Ikenouchi Atsuko, Igata Ryohei, Konishi Yuki, Natsuyama Tomoya, Fujii Rintaro, Kakeda Shingo, Kishi Taro, Iwata Nakao, Yoshimura Reiji
Neurology international, Apr. 2022, Reviewed, No invitation
Lead

Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia.
Natsuyama Tomoya, Chibaatar Enkhmurun, Shibata Yuko, Okamoto Naomichi, Cruz Victorino John Noel, Ikenouchi Atsuko, Shibata Tomohiro, Yoshimura Reiji
Neuropsychiatric disease and treatment, Apr. 2025, Reviewed, No invitation

Serum Lipidome Change in Japanese Patients with Major Depressive Disorder: A Real-World Exploratory Study.
Okamoto Naomichi, Fujii Rintaro, Chibaatar Enkhmurun, Iino Chihiro, Ikenouchi Atsuko, Yoshimura Reiji
Neuropsychiatric disease and treatment, Aug. 2025, Reviewed, No invitation

Associations of Serum Cytokines, Growth Factors, and High-Sensitivity C-Reactive Protein Levels in Patients with Major Depression with and without Type 2 Diabetes Mellitus: An Explanatory Investigation.
Hoshikawa Takashi, Okamoto Naomichi, Natsuyama Tomoya, Fujii Rintaro, Ikenouchi Atsuko, Honma Yuichi, Harada Masaru, Yoshimura Reiji
Neuropsychiatric disease and treatment, Jan. 2022, Reviewed, No invitation

Association of Serum Kynurenine Levels and Neural Networks in Patients with First-Episode, Drug-Naïve Major Depression: A Source-Based Morphometry Study.
Okamoto Naomichi, Watanabe Keita, Ngyuyen LeHoa, Ikenouchi Atsuko, Kishi Taro, Iwata Nakao, Kakeda Shingo, Korogi Yukunori, Yoshimura Reiji
Neuropsychiatric disease and treatment, Oct. 2020, Reviewed, No invitation
Lead

Risk Factors in Japanese Drug Overdose Patients: Identifying Their Associations With Suicide Risk
Naomichi Okamoto, Atsuko Ikenouchi, Enkhmurun Chibaatar, Keita Watanabe, Ryohei Igata, Issei Seki, Reiji Yoshimura
OMEGA Journal of Death and Dying, Mar. 2023, Reviewed, No invitation
Lead

A CASE OF PERSISTENT DEPRESSIVE DISORDER WITH A SIGNIFICANT RESPONSE TO THE ADDITION OF LURASIDONE TO VORTIOXETINE.
Yoshimura Reiji, Okamoto Naomichi, Hamada Shinsuke, Ikenouchi Atsuko
Psychiatria Danubina, Aug. 2023, Reviewed, No invitation

Duloxetine Does not Affect Vascular Endothelial Growth Factor Plasma Levels in Patients with First-Episode, Drug-Naïve Major Depression
Reiji Yoshimura, Naomichi Okamoto, Atsuko Ikenouchi
Psychiatria Danubina, Mar. 2023, Reviewed, No invitation

Effects of Paroxetine on Plasma Levels of Vascular Endothelial Growth Factor in Patients with Major Depression.
Yoshimura Reiji, Okamoto Naomichi, Ikenouchi Atsuko
Psychiatria Danubina, Oct. 2022, Reviewed, No invitation

Differences in the Disease Severity and Background Characteristics of Patients with Suicide Attempts Due to Overdose According to the Time of Day.
Hirashima Tatsuro, Okamoto Naomichi, Ikenouchi Atsuko, Mayumi Toshihiko, Yoshimura Reiji
Psychiatria Danubina, Jul. 2022, Reviewed, No invitation
Corresponding

L-Arginine-Nitric Oxide Pathway and Neural Networks in Major Depression.
Okamoto Naomichi, Watanabe Keita, Ikenouchi Atsuko, Korogi Yukinori, Yoshimura Reiji
Psychiatria Danubina, Apr. 2022, Reviewed, No invitation
Lead

A Case of Major Depression Comorbid with Social Phobia Treated Successfully with Vortioxetine.
Yoshimura Reiji, Okamoto Naomichi
Psychiatria Danubina, Dec. 2020, Reviewed, No invitation
Last

Isolated Adrenocorticotropic Hormone Deficiency accompanied by impaired cognitive function: A case report
Atsuko Ikenouchi, Issei Seki, Naomichi Okamoto, Yuki Konishi, Reiji Yoshimura
Psychiatry Research Case Reports, Sep. 2022, Reviewed, No invitation

Human immunodeficiency virus-related neurocognitive disorder with _x000D_ hallucinations and delusions: A case report
Junpei Igata, Naomichi Okamoto, Hirofumi Tesen, Maya Akiyama, Satoru Ide, Atsuko Ikenouchi, Reiji Yoshimura
Psychiatry Research Case Reports, Nov. 2023, Reviewed, No invitation
Corresponding

Human immunodeficiency virus-related neurocognitive disorder with hallucinations and delusions: A case report
Junpei Igata, Naomichi Okamoto, Hirofumi Tesen, Maya Akiyama, Satoru Ide, Atsuko Ikenouchi, Reiji Yoshimura
Psychiatry Research Case Reports, Jun. 2024, Reviewed, Null
Corresponding

A case of 10-year retrograde amnesia, cognitive dysfunction, and hippocampal atrophy after limbic encephalitis associated with rickettsiosis
Naomichi Okamoto,Atsuko Ikenouchi,Shoichi Shimizu,Satoru Ide,Enkhmurun Chibaatar,Reiji Yoshimura
Psychiatry Research Case Reports, Dec. 2023, Reviewed, No invitation
Lead

Comparison of plasma catecholamine metabolites in melancholic and non-melancholic depression
Reiji Yoshimura, Naomichi Okamoto, Atsuko Ikenouchi
Psychiatry Research Communications, Jun. 2022, Reviewed, No invitation

No interaction between plasma IL-6 and MHPG in major depression treated with paroxetine
Reiji Yoshimura, Naomichi Okamoto, Atsuko Ikenouchi
Psychiatry Research Communications, Sep. 2022, Reviewed, No invitation

Effect of risperidone on plasma vascular endothelial growth factor levels in _x000D_ patients with first-episode schizophrenia: A preliminary study
Reiji Yoshimura, Naomichi Okamoto, Gaku Hayasaki, Issei Seki, Reoto Kijima, Enkmurun Chibaatar, Atsuko Ikenouchi
Psychiatry Research Communications, Dec. 2023, Reviewed, No invitation

Mania after long-term treatment with daily 10 mg prednisolone
Rintaro Fujii, Yuki Konishi, Ryutaro Furusawa, Naomichi Okamoto, Reiji Yoshimura
Psychiatry and clinical neurosciences Reports, Dec. 2022, Reviewed, No invitation

Auditory hallucinations of Buddhist chanting as an initial symptom of mild cognitive impairment with Lewy bodies
Naomichi Okamot, Atsuko Ikenouchi, Tatsuro Hirashima, Hirofumi Tesen, Satoru Ide, Reiji Yoshimura
Psychogeriatrics, Jul. 2023, Reviewed, No invitation
Lead, Corresponding

A male case of frontotemporal lobar degeneration with behavioural and psychiatric symptoms responding to a low dose of escitalopram.
Ikenouchi Atsuko, Seki Issei, Takaoka Kei, Okamoto Naomichi, Murakami Sayuri, Yoshimura Reiji
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, Feb. 2021, Reviewed, No invitation

Low-dose lamotrigine induces Pisa syndrome in a patient with probable corticobasal degeneration despite previous use.
Okamoto Naomichi, Sakakibara Takahiro, Tsukada Nagiho, Chibaatar Enkhmurun, Hayasaki Gaku, Konishi Yuki, Ikenouchi Atsuko, Yoshimura Reiji
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, Nov. 2024, Reviewed, No invitation
Lead, Corresponding

A case of folate deficiency showing behavioural variant of frontotemporal dementia-like symptoms.
Fujii Arisa, Ikenouchi Atsuko, Okamoto Naomichi, Fujii Rintaro, Ide Satoru, Yoshimura Reiji
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, Mar. 2024, Reviewed, No invitation

A case of exploding head syndrome preceding the onset of mild cognitive impairment with Lewy bodies.
Kitagawa Shogo, Okamoto Naomichi, Ikenouchi Atsuko, Igata Ryohei, Hashimoto Reia, Konishi Yuki, Tesen Hirofumi, Yoshimura Reiji
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, Jan. 2023, Reviewed, No invitation
Corresponding

Effect of Milnacipran on Plasma Level of Vascular Endothelial Growth Factor in Major Depression.
Yoshimura Reiji, Ikenouchi Atsuko, Okamoto Naomichi
Psychopharmacology bulletin, Oct. 2022, Reviewed, No invitation

Vortioxetine improved olfactory reference syndrome in a patient with major depressive disorder: A case report.
Yoshimura R, Konishi Y, Okamoto N, Ikenouchi A
Revista de Psiquiatria Clinica, Jul. 2021, Reviewed, No invitation

Plasma paroxetine level is independent of the change in plasma interleukin-6 level in remitted patients with major depressive disorder.
Yoshimura R, Okamoto N, Konishi Y, Ikenouchi A
Revista de Psiquiatria Clinica, Jul. 2021, Reviewed, No invitation

Prisoner's dilemma game in recovered schizophrenia patients, compared with healthy controls: Preliminary findings.
Igata Ryohei, Tesen Hirofumi, Konishi Yuki, Ikenouchi Atsuko, Okamoto Naomichi, Yoshimura Reiji
Schizophrenia research, Jul. 2021, Reviewed, No invitation

Associations between plasma levels of C-reactive protein and catecholamine metabolites in patients with major depression
Reiji Yoshimura, Naomichi Okamoto, Yuki Konishi and Atsuko Ikenouchi
Therapeutic Advances in Psychopharmacology, May 2021, Reviewed, No invitation

Plasma levels of interleukin-6 and 3-methoxy-4-hydroxyphenylglycol and treatment with milnacipran in major depression.
Yoshimura Reiji, Okamoto Naomichi, Ikenouchi Atsuko
Therapeutic advances in psychopharmacology, Aug. 2022, Reviewed, No invitation

Comparison of psychiatric symptoms between patients with major depression with higher and lower levels of high-sensitivity C-reactive protein in the serum: a preliminary study.
Okamoto Naomichi, Hoshikawa Takashi, Ikenouchi Atsuko, Yoshimura Reiji
Therapeutic advances in psychopharmacology, Nov. 2021, Reviewed, No invitation
Lead

PATIENT WITH PARKINSON'S DISEASE AND DEPRESSIVE SYMPTOMS ASSOCIATED WITH IMPULSE CONTROL DISORDER.
Migita Kanae, Okamoto Naomichi, Ikenouchi Atsuko, Kijima Reoto, Hashimoto Tomoyo, Adachi Hiroaki, Yoshimura Reiji
Psychiatria Danubina, May 2024, Reviewed, No invitation