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Last Updated :2026/06/12



Internal Medicine 3
Lecturer

Research activity information

■ Paper
  • Long-chain fatty acyl CoA synthetase 4 expression in pancreatic cancer: a marker for malignant lesions and prognostic indicator for recurrence
    Daiki Uchihara; Shohei Shimajiri; Yoshikazu Harada; Keiichiro Kumamoto; Shinji Oe; Koichiro Miyagawa; Koichi Nakamura; Eisuke Katafuchi; Fariza Nuratdinova; Yuichi Honma; Michihiko Shibata; Masaru Harada; Toshiyuki Nakayama
    Diagnostic Pathology, May 2025, Reviewed
  • Usefulness of the Early Increase of Peripheral Blood Lymphocyte Count in Predicting Clinical Outcomes for Patients with Advanced Hepatocellular Carcinoma Treated with Durvalumab Plus Tremelimumab
    Yuichi Honma; Michihiko Shibata; Masatoshi Ikemi; Kengo Yoshitomi; Nobuhiko Shinohara; Noriyoshi Ogino; Shinji Oe; Koichiro Miyagawa; Shintaro Abe; Masaru Harada
    Cancers, Apr. 2025, Reviewed
  • 【アルコールと肝疾患 up to date】総論 アルコールと肝疾患
    原田 大, 本間 雄一, 柴田 道彦
    日本消化器病学会雑誌, Jan. 2022, Reviewed, Null
    Last
  • ウイルス性肝炎関連肝癌症例の通院状況に関する検討
    柴田 道彦, 南 創太, 大江 晋司, 宮川 恒一郎, 本間 雄一, 鬼塚 良, 千手 倫夫, 日浦 政明, 原田 理子, 阿部 慎太郎, 田原 章成, 原田 大
    日本消化器病学会雑誌, Oct. 2016, Reviewed, Null
    Lead
  • TfR2ヘテロ接合型変異で発症したヘモクロマトーシスの1例
    西尾 仁, 本間 雄一, 熊元 啓一郎, 土岐 康通, 森野 加帆里, 大江 晋司, 宮川 恒一郎, 柴田 道彦, 阿部 慎太郎, 巽 康彰, 生田 克哉, 林 久男, 原田 大
    肝臓, Mar. 2022, Reviewed, Null
  • 直接経口抗凝固薬の使用が肝細胞癌の診断に有用であった1例
    烏山 司, 本間 雄一, 日高 弘晴, 森野 加帆里, 小屋 有代, 日浦 政明, 柴田 道彦, 原田 大
    肝臓, Jan. 2019, Reviewed, Null
  • アセトアミノフェンによる急性肝不全・急性型の1例
    米田 晃敏, 日浦 政明, 烏山 司, 本間 雄一, 柴田 道彦, 蒲地 正幸, 原田 大
    肝臓, Jul. 2018, Reviewed, Null
  • 術後急性肝障害の1例
    米田 晃敏, 日浦 政明, 本間 雄一, 柴田 道彦, 原田 大
    臨牀と研究, Jun. 2018, Reviewed, Null
  • 診断に苦慮した肝腫瘤
    池見 雅俊, 本間 雄一, 草永 真志, 柴田 道彦, 原田 大
    臨牀と研究, May 2023, Null, Null
  • Antiplatelet therapy improves the prognosis of patients with hepatocellular carcinoma.
    Hayashi T, Shibata M, Oe S, Miyagawa K, Honma Y, Harada M.
    Cancers, Oct. 2020, Reviewed, Null
  • Spontaneous regression of hepatocellular carcinoma with portal vein tumor thrombus.
    Koya Y, Suzuki T, Tai M, Ichii O, Matsuhashi N, Ejiri Y, Shibata M, Harada M
    Case reports in gastroenterology, Aug. 2018, Reviewed, Null
  • Autoimmune hepatitis complicated by adult-onset Still's disease during treatment with tocilizumab: A case report from acute onset to recurrence.
    Uchihara D, Suzuki T, Koya Y, Tai M, Ichii O, Matsuhashi N, Ejiri Y, Kato T, Honma Y, Shibata M, Harada M
    Clinical Case Reports, Jul. 2023, Reviewed, Null
  • A case of adrenal metastasis of hepatocellular carcinoma diagnosed by endoscopic ultrasound-guided fine-needle aspiration.
    Ueda T, Oe S, Yoneda A, Koya Y, Nebuya S, Miyagawa K, Honma Y, Shibata M, Shimajiri S, Harada M
    DEN Open, Apr. 2024, Reviewed, Null
  • Impact of examining additional deeper sections on the pathological diagnosis of endoscopically resected early gastric cancer.
    Kumei S, Nakayama T, Watanabe T, Kumamoto K, Noguchi H, Shibata M, Kume K, Yoshikawa I, Harada M
    Digestive Endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, Jul. 2019, Reviewed, No invitation
  • Impact of Interferon-free direct-acting antivirals on the incidence of extrahepatic malignancies in patients with chronic hepatitis C.
    Honma Y, Shibata M, Morino K, Koya Y, Hayashi T, Ogino N, Kusanaga M, Oe S, Miyagawa K, Abe S, Tabaru A, Harada M
    Digestive diseases and sciences, Feb. 2023, Reviewed, Null
  • Influence of gastroesophageal flap valve on esophageal variceal bleeding in patients with liver cirrhosis.
    Koya Y, Shibata M, Watanabe T, Kumei S, Miyagawa K, Oe S, Honma Y, Kume K, Yoshikawa I, Harada M.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, Jan. 2021, Reviewed, Null
  • Serum Albumin Concentrations Predict hypovolaemia Caused by Polyethylene Glycol Plus Ascorbic Acid Prior to Colonoscopy in Elderly Patients.
    Ogino Noriyoshi, Aridome Gentaro, Oshima Junji, Shibata Michihiko, Watanabe Tatsuyuki, Kume Keiichiro, Yoshikawa Ichiro, Harada Masaru
    Drugs & aging, May 2016, Reviewed, Null
  • CD169 expression on lymph node macrophages predicts in patients with gastric cancer.
    Kumamoto K, Tasaki T, Ohnishi K, Shibata M, Shimajiri S, Harada M, Komohara Y, Nakayama T
    Frontiers in oncology, Mar. 2021, Reviewed, Null
  • Low skeletal muscle mass and high visceral adiposity are associated with recurrence of acute cholecystitis after conservative management: A propensity score-matched cohort study.
    Koya Y, Shibata M, Maruno Y, Sakamoto Y, Oe S, Miyagawa K, Honma Y, Harada M
    Hepatobiliary & Pancreatic Diseases International : HBPD INT, Feb. 2024, Reviewed, Null
  • Secondary sclerosing cholangitis with hemobilia induced by pembrolizumab: Case report and review of published work.
    Koya Y, Shibata M, Shinohara N, Nebuya S, Oe S, Honma Y, Senju M, Sato N, Harada M
    Hepatology Research, Aug. 2019, Reviewed, Null
  • Churg-Strauss syndrome manifesting as cholestasis and diagnosed by liver biopsy.
    Harada Masaru, Oe Shinji, Shibata Michihiko, Taguchi Masashi, Matsuhashi Toru, Hiura Masaaki, Abe Shintaro, Harada Riko, Shimajiri Shohei
    Hepatology research : the official journal of the Japan Society of Hepatology, Sep. 2012, Reviewed, Null
  • Late diagnosed Wilson disease with hepatic and neurological manifestations.
    Honma Yuichi, Harada Masaru, Sato Miyuki, Katsuki Yuka, Hiura Masaaki, Shibata Michihiko, Narita Ryoichi, Harada Riko, Abe Shintaro, Tabaru Akinari, Tajiri Nobuyoshi, Shimajiri Shohei
    Hepatology research : the official journal of the Japan Society of Hepatology, Mar. 2011, Reviewed, Null
  • An unusual abscess associated with gallbladder perforation successfully treated with percutaneous transhepatic gallbladder drainage and endoscopic ultrasound-guided abscess drainage.
    Miyagawa K, Kajitani K, Makita T, Hideshima K, Shinohara N, Oe S, Honma Y, Shibata M, Harada M.
    Internal Medicine (Tokyo, Japan), Sep. 2024, Reviewed, Null
  • Two cases with isolated splenic sarcoidosis diagnosed by an ultrasound-guided fine-needle aspiration biopsy.
    Tanimoto A, Shibata M, Honma Y, Morino K, Kusanaga M, Abe S, Harada M
    Internal Medicine (Tokyo, Japan), Jul. 2023, Reviewed, Null
  • Hepatic inflammatory pseudotumor protruding from the liver surface and directly penetrating the colon.
    Imazu N, Shibata M, Koya Y, Morino K, Honma Y, Senju M, Watanabe T, Harada M.
    Internal Medicine (Tokyo, Japan), Feb. 2020, Reviewed, Null
  • Importance of a liver biopsy in the management of Wilson dsease.
    Oe S, Honma Y, Yabuki K, Morino K, Kumamoto K, Hayashi T, Kusanaga M, Ogino N        , Minami S, Shibata M, Abe S, Harada M.
    Internal Medicine (Tokyo, Japan), Jan. 2020, Reviewed, Invited
  • Hyperammonemia in a woman with late-onset ornithine transcarbamylase deficiency.
    Koya Y, Shibata M, Senju M, Honma Y, Hiura M, Ishii M, Matsumoto S, Harada M.
    Internal Medicine (Tokyo, Japan), Apr. 2019, Reviewed, Null
  • Inflammatory hepatocellular adenoma with elevated serum protein Induced by vitamin K absence/antagonist-II in adult males.
    Koya Y, Suzuki T, Tai M, Ichii O, Matsuhashi N, Ejiri Y, Miyazawa M, Shibata M, Harada M, Kumabe T, Nakashima O
    Internal Medicine (Tokyo, Japan), Jun. 2019, Reviewed, Null
  • Impact of the concomitant use of immunomodulator and a lower week 8 partial Mayo score on the persistence of adalimumab in refractory ulcerative colitis.
    Kumei S, Sakurai T, So S, Itaba S, Akiho H, Nakamura S, Kim H, Yamasaki M, Takatsu N, Maekawa R, Sakemi R, Watanabe T, Shibata M, Kume K, Yoshikawa I, Takaki Y, Harada M
    Internal medicine (Tokyo, Japan), Dec. 2021, Reviewed, Null
  • Rapidly progressing anaplastic carcinoma of the pancreas with mucoepidermoid carcinoma: An autopsy case report.
    Imazu N, Oe S, Tsuda Y, Nebuya S, Koya Y, Miyagawa K, Honma Y, Shibata M, Harada M
    Internal medicine (Tokyo, Japan), Jul. 2021, Reviewed, Null
  • Rapid progression of liver fibrosis induced by acute liver injury due to immune-related adverse events of atezolizumab.
    Honma Y, Shibata M, Gohda T, Matsumiya H, Kumamoto K, Miyama A, Morino K, Koya Y, Taira A, Shinohara S, Hayashi T, Kusanaga M, Oe S, Miyagawa K, Abe S, Tanaka F, Harada M.
    Internal medicine (Tokyo, Japan), Jan. 2021, Reviewed, Null
  • Prediction of Disseminated Intravascular Coagulation by Liver Function Tests in Patients with Japanese Spotted Fever.
    Miyashima Y, Iwamuro M, Shibata M, Miyabe Y, Kawai Y, Kaihara M, Mitogawa T, Harada M
    Internal medicine (Tokyo, Japan), Jan. 2018, Reviewed, Null
  • Severe alcoholic hepatitis effectively treated with vitamin E as an add-on to corticosteroids.
    Miyashima Y, Shibata M, Honma Y, Matsuoka H, Hiura M, Abe S, Harada M
    Internal medicine (Tokyo, Japan), Dec. 2017, Reviewed, Null
  • Bullous pemphigoid associated with the dipeptidyl peptidase-4 inhibitor sitagliptin in a patient with liver cirrhosis complicated with rapidly progressive hepatocellular carcinoma.
    Harada M, Yoneda A, Haruyama S, Yabuki K, Honma Y, Hiura M, Shibata M, Matsuoka H, Uchiwa Y
    Internal medicine (Tokyo, Japan), Aug. 2017, Reviewed, Null
  • Reactivation of occult hepatitis B virus infection 27 months after the end of chemotherapy including rituximab for malignant lymphoma.
    Muraishi J, Shibata M, Honma Y, Hiura M, Abe S, Harada M
    Internal medicine (Tokyo, Japan), Aug. 2017, Reviewed, Null
  • Daclatasvir and Asunaprevir Combination Therapy-induced Hepatitis and Cholecystitis with Coagulation Disorder due to Hypersensitivity Reactions.
    Miyashima Yuichi, Honma Yuichi, Miyagawa Koichiro, Oe Shinji, Senju Michio, Shibata Michihiko, Hiura Masaaki, Abe Shintaro, Harada Masaru
    Internal medicine (Tokyo, Japan), Dec. 2016, Reviewed, Null
  • Methotrexate-related primary hepatic lymphoma in a patient with rheumatoid arthritis.
    Miyagawa Koichiro, Shibata Michihiko, Noguchi Hirotsugu, Hayashi Tsuguru, Oe Shinji, Hiura Masaaki, Abe Shintaro, Harada Masaru
    Internal medicine (Tokyo, Japan), Feb. 2015, Reviewed, Null
  • Hepatic peribiliary cysts with rapidly progressive refractory obstructive jaundice and esophageal varices.
    Shibata Michihiko, Hiura Masaaki, Senju Michio, Matsuhashi Toru, Abe Shintaro, Morita Chie, Hayashida Kazuhiro, Tabaru Akinari, Harada Masaru
    Internal medicine (Tokyo, Japan), Feb. 2015, Reviewed, Null
    Lead
  • Acute Liver Failure Complicated with Severe Heart Failure.
    Minami Sota, Shibata Michihiko, Matsuhashi Toru, Hiura Masaaki, Abe Shintaro, Harada Masaru
    Internal medicine (Tokyo, Japan), Oct. 2015, Reviewed, Null
  • Refractory primary hepatic actinomycosis with direct infiltration to the diaphragm and thorax: the usefulness of contrast-enhanced ultrasonography.
    Oe Shinji, Shibata Michihiko, Hiura Masaaki, Mitsuoka Hiroshi, Matsuhashi Toru, Narita Ryoichi, Abe Shintaro, Tabaru Akinari, Hayashida Kazuhiro, Taniguchi Hatsumi, Harada Masaru
    Internal medicine (Tokyo, Japan), Sep. 2014, Reviewed, Null
  • Excess copper chelating therapy for Wilson disease induces anemia and liver dysfunction.
    Harada Masaru, Miyagawa Koichiro, Honma Yuichi, Hiura Masaaki, Shibata Michihiko, Matsuhashi Toru, Abe Shintaro, Harada Riko, Tabaru Akinari
    Internal medicine (Tokyo, Japan), Jul. 2011, Reviewed, Null
  • A Case of successful endoscopic extraction of common bile duct stones after closing a duodenal perforation using over-the-scope clip.
    Oe S, Kumei S, Karasuyama T, Shinohara N, Hideshima K, Yoneda A, Miyagawa K, Honma Y, Shibata M, Harada M
    Journal of UOEH, Jun. 2023, Null, Null
  • Hepatic cyst infection following recurrent biliary obstruction in polycystic liver disease.
    Miyagawa K, Nakano Y, Yoneda A, Kusanaga M, Oe S, Honma Y, Shibata M, Harada M
    Journal of UOEH, Dec. 2022, Null, Null
  • A case of pancreatic neuroendocrine tumor G3 which responded remarkably to chemotherapy.
    Nebuya S, Oe S, Harada Y, Takeuchi Y, Yoneda A, Koya Y, Miyagawa K, Honma Y, Shibata M, Harada M
    Journal of UOEH, Sep. 2022, Reviewed, No invitation
  • Hepatocyte growth factor and primary systemic amyloidosis.
    Karasuyama T, Honma Y, Kumamoto K, Shibata M, Watanabe T, Shimajiri S, Abe S, Yamashita T, Harada M
    Journal of UOEH, Jun. 2021, Reviewed, Null
  • A case of idiopathic gastroesophageal submucosal hematoma and its disappearance observed by endoscopy.
    Oe Shinji, Watanabe Tatsuyuki, Kume Keiichiro, Shibata Michihiko, Hiura Masaaki, Yoshikawa Ichiro, Harada Masaru
    Journal of UOEH, Jun. 2014, Reviewed, Null
  • Impact of sarcopenia on recurrent biliary obstruction after insertion of self-expandable metallic stent in patients with malignant biliary obstruction.
    Koya Y, Shibata M, Oe S, Honma Y, Nebuya S, Miyagawa K, Yoshikawa I, Harada M
    Journal of hepato-biliary-pancreatic sciences, Jul. 2021, Reviewed, Null
  • Effect of direct-acting antivirals on platelet-associated immunoglobulin G and thrombocytopenia in hepatitis C virus-related chronic liver disease.
    Honma Y, Shibata M, Hayashi T, Kusanaga M, Ogino N, Minami S, Kumei S, Oe S, Miyagawa K, Senju M, Matsuoka H, Watanabe T, Hiura M, Abe S, Harada M.
    Liver International, Sep. 2019, Reviewed, Null
  • Idiopathic copper toxicosis: is abnormal copper metabolism a primary cause of this disease?
    Harada M, Honma Y, Yoshizumi T, Kumamoto K, Oe S, Harada N, Tanimoto A, Yabuki K, Karasuyama T, Yoneda A, Shibata M.
    Medical Molecular Morphology, Mar. 2020, Reviewed, Null
    Corresponding
  • Type 4B hereditary hemochromatosis due to heterozygous p.D157A mutation in SLC40A1 complicated with hypopituitarism.
    Honma Y, Karasuyama T, Kumamoto K, Shimajiri S, Toki Y, Tatsumi Y, Sumida K, Koikawa K, Morino K, Oe S, Miyagawa K, Yamasaki M, Shibata M, Abe S, Ikuta K, Hayashi H, Harada M
    Medical molecular morphology, Mar. 2021, Reviewed, Null
  • C-reactive protein can predict dose intensity, time to treatment failure and overall survival in HCC treated with lenvatinib.
    Hayashi T, Shibata M, Oe S, Miyagawa K, Honma Y, Harada M.
    PloS one, Dec. 2020, Reviewed, Null
  • Endoscopic injection sclerotherapy improves liver function compared with endoscopic variceal ligation.
    Hayashi T, Watanabe T, Shibata M, Kumei S, Oe S, Miyagawa K, Honma Y, Harada M.
    Scientific Reports, Oct. 2021, Reviewed, Null
  • Child-Pugh grade deterioration stratified by the etiology after transcatheter arterial chemoembolization as initial treatment for hepatocellular carcinoma.
    Yoshitomi K, Hayashi T, Oe S, Shibata M, Honma Y, Harada M, Kooka Y
    Scientific reports, Feb. 2024, Reviewed, Null
  • Trends in hepatocellular carcinoma incident cases in Japan between 1996 and 2019.
    Nakano M, Yatsuhashi H, Bekki S, Takami Y, Tanaka Y, Yoshimaru Y, Honda K, Komorizono Y, Harada M, Shibata M, Sakisaka S, Shakado S, Nagata K, Yoshizumi T, Itoh S, Sohda T, Oeda S, Nakao K, Sasaki R, Yamashita T, Ido A, Mawatari S, Nakamuta M, Aratake Y, Matsumoto S, Maeshiro T, Goto T, Torimura T
    Scientific reports, Jan. 2022, Reviewed, Null
  • Comparison of efficacy and safety of atezolizumab plus bevacizumab and lenvatinib as first-line therapy for unresectable hepatocellular carcinoma: a propensity score matching analysis.
    Niizeki T, Tokunaga T, Takami Y, Wada Y, Harada M, Shibata M, Nakao K, Sasaki R, Hirai F, Shakado S, Yoshizumi T, Itoh S, Yatsuhashi H, Bekki S, Ido A, Mawatari S, Honda K, Sugimoto R, Senju T, Takahashi H, Kuwashiro T, Maeshiro T, Nakamuta M, Aratake Y, Yamashita T, Otsuka Y, Matsumoto S, Sohda T, Shimose S, Murotani K, Tanaka Y
    Targeted oncology, Nov. 2022, Reviewed, Null
  • Hepatitis A complicated with acute renal failure and high hepatocyte growth factor: A case report.
    Oe Shinji, Shibata Michihiko, Miyagawa Koichiro, Honma Yuichi, Hiura Masaaki, Abe Shintaro, Harada Masaru
    World journal of gastroenterology, Aug. 2015, Reviewed, Null
  • Airborne fine particulate matter in Japan induces lipid synthesis and inhibits autophagy in HepG2 cells.
    Ogino N, Miyagawa K, Nagaoka K, Sumida K, Kusanaga M, Oe S, Honma Y, Shibata M, Harada M, Suganuma N, Ogino K
    The international journal of biochemistry & cell biology, Dec. 2021, Reviewed, Null
  • A young adult patient with nonalcoholic steatohepatitis developed severe gastroesophageal varices associated with severe obesity and diabetes mellitus.
    Honma Y, Sumida K, Ogino N, Kusanaga M, Minami S, Kumei S, Matsuoka H, Watanabe T, Hiura M, Abe S, Shibata M, Harada M
    Case reports in gastroenterology, Aug. 2018, Reviewed, Null