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Last Updated :2026/06/12



Occupational Oncology
Associate Professor

Researcher information

■ Research Keyword
■ Field Of Study
  • Life sciences, Pharmacology
  • Humanities & social sciences, Home economics, lifestyle science

Career

■ Career
  • 202009, 9999
    University of Occupational and Environmental Health, Japan, Institute of Industrial Ecological Sciences, Associate Professor
  • 201704, 202008
    University of Occupational and Environmental Health, Institute of Industrial Ecological Sciences, Assistant Professor
  • 200610, 201703
    University of Occupational and Environmental Health, Institute of Industrial Ecological Sciences, Research associate
  • 200001, 200308
    Yanbian University, China, Agriculture College, Assistant Professor
  • 199407, 199912
    Yanbian University, China, Agriculture College, Research Associate
■ Educational Background
  • Oct. 2003 - Sep. 2006, Okayama University, Graduate School of Natural Science & Technology, 生体機能専攻
  • Oct. 2000 - Sep. 2001, Agriculture University of Poznan, Faculty of Horticulture
  • Sep. 1996 - Jul. 1999, Yanbian University, China, Faculty of Agriculture

Research activity information

■ Award
  • Nov. 2019
    日本環境変異原学会, Genes and Environment 2018 Best Paper Award
    Measurement of 8-hydroxyguanine as an oxidative stress biomarker in saliva by HPLC-ECD
    Kawai K;Kasai H;Li Y-S
  • Nov. 2017
    The 12th International Conference & 5th Asian Congress on Environmental Mutagens with the 33rd Annual Meeting of KSOT/KEMS, Best Presentation Award
    Yun-Shan Li
  • 2013
    日本変異原学会学会誌, 優秀論文賞
    李 云善
  • Oct. 2012
    The 3rd Asian Conference on Environmental Mutagens & 15th Cofference of Chinese Environmental Mutagen Society, Best Poster Award
    Yun-Shan Li
  • 2010
    日本産業医科大学学会, 第28回産業医科大学学会総会優秀ポスター賞
    李 云善
  • 2008
    日本変異原学会, 第37回日本変異原学会キャノン賞
    李 云善
■ Paper
  • Assessment of urinary cotinine levels in heated tobacco product (HTP) users: Effectiveness of enzyme-linked immunosorbent assay (ELISA)
    姜英; 河井一明; 李云善; 垣内紀亮; 大和浩
    日本公衆衛生雑誌, Nov. 2025, Reviewed
  • Effects of ergothioneine on oxidative DNA damage and immune response induced by circadian rhythm disturbance in mice
    Yun-Shan Li; Koichi Fujisawa; Kazuaki Kawai
    J Clin Biochem Nutr, Mar. 2025, Reviewed, No invitation
    Lead, Corresponding
  • Diurnal and daily fluctuations in levels of the urinary oxidative stress marker 8-hydroxyguanosine in spot urine samples
    Yun-Shan Li; Koichi Fujisawa; Kazuaki Kawai
    Genes and Environment, Jan. 2025, Reviewed
    Lead, Corresponding
  • Effect of circadian rhythm disruption induced by ‍time-restricted feeding and exercise on ‍oxidative stress and immune in mice
    Yun-Shan Li; Hiroaki Fujihara; Koichi Fujisawa; Kazuaki Kawai
    Journal of Clinical Biochemistry and Nutrition, Jan. 2025, Reviewed
    Lead, Corresponding
  • The Association between Oxidative Balance Score and Urinary Levels of 8-Hydroxydeoxyguanosine among Japanese Adults.
    Hinako Nanri; Megumi Hara; Yuichiro Nishida; Chisato Shimanoe; Yun-Shan Li; Hiroshi Kasai; Kazuaki Kawai; Yasuki Higaki; Keitaro Tanaka
    Nutrients, Oct. 2023, Reviewed
  • Assessment of exposure and DNA damage from second-hand smoke using potential biomarker in urine: cigarettes and heated tobacco products.
    Yuya Kawasaki; Yun-Shan Li; Yuko Ootsuyama; Koichi Fujisawa; Hisamitsu Omori; Ayumi Onoue; Kenichi Kubota; Toshimi Yoshino; Yoshio Nonami; Minoru Yoshida; Hiroshi Yamato; Kazuaki Kawai
    Journal of clinical biochemistry and nutrition, May 2023, Reviewed
  • Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model.
    Yosuke Mano; Manabu Tsukamoto; Ke-Yong Wang; Takayuki Nabeshima; Kenji Kosugi; Takafumi Tajima; Yoshiaki Yamanaka; Hitoshi Suzuki; Makoto Kawasaki; Eiichiro Nakamura; Qian Zhou; Kagaku Azuma; Tamiji Nakashima; Yuki Tamura; Karina Kozaki; Koichi Nakazato; Yun-Shan Li; Kazuaki Kawai; Kazuhiro Yatera; Akinori Sakai
    Journal of bone and mineral metabolism, Nov. 2022, Reviewed
  • Urinary biomarkers for secondhand smoke and heated tobacco products exposure.
    Yuya Kawasaki; Yun-Shan Li; Sintaroo Watanabe; Yuko Ootsuyama; Kazuaki Kawai
    Journal of clinical biochemistry and nutrition, Jul. 2021, Reviewed
  • Diurnal and day-to-day variation of urinary oxidative stress marker 8-hydroxy-2'-deoxyguanosine.
    Yun-Shan Li; Yuya Kawasaki; Sintaroo Watanabe; Yuko Ootsuyama; Hiroshi Kasai; Kazuaki Kawai
    Journal of clinical biochemistry and nutrition, Jan. 2021, Reviewed
    Lead
  • Health examination results and work environment factors affecting urinary 8-hydroxy-2'-deoxyguanosine levels.
    Sintaroo Watanabe; Yun-Shan Li; Yuya Kawasaki; Yuko Ootsuyama; Kazuaki Kawai
    Journal of occupational health, Jan. 2021, Reviewed
  • Effects of smoking cessation on biological monitoring markers in urine
    Kawasaki Y; Li Y-S; Ootsuyama Y; Nagata K; Yamato H; Kawai K
    Genes Environ., Sep. 2020, Reviewed
  • Workersʼ Lifestyles and Urinary 8-hydroxydeoxyguanosine as an Oxidative Stress Marker
    Sintaroo Watanabe; Yun-Shan Li; Yuya Kawasaki; Kazuaki Kawai
    J UOEH(, Nov. 2019, Reviewed
  • Pilot clinical study of ascorbic acid treatment in cardiac catheterization
    Sun L; Igarashi T; Tetsuka R; Yun-Shan Li
    J Radiat Res., Jun. 2019, Reviewed, No invitation
  • Leisure-time physical activity and DNA damage among Japanese workers.
    Kawakami R; Kashino I; Kasai H; Kawai K; Li Yun-Shan
    PLoS One, Feb. 2019, Reviewed, No invitation
  • Mental/Physical Stress Levels of Female Nurses’ Working Rotational Shifts
    Anan A; Yun-Shan Li; Tsuji M; Nagamatsu Y; Chou S; Toyofuku K; Kawai K
    JJOMT, 2019, Reviewed, No invitation
  • Measurement of 8-Hydroxyguanine as an oxidative stress biomarker in saliva by HPLC-ECD
    Kawai K; Kasai H; Yun-Shan Li; Kawasaki Y; Watanabe S; Ohta M; Honda T; Yamato H
    Gene and environment, Apr. 2018, Reviewed, No invitation
  • Dietary non-enzymatic antioxidant capacity and DNA damage in a working population
    Ikuko Kashino; Yun-Shan Li; Kazuaki Kawai; Akiko Nanri; Takako Miki; Shamima Akter; Satomi Kobayashi; Hiroshi Kasai; Tetsuya Mizoue
    Nutrition, Mar. 2018, Reviewed, No invitation
  • Oxidative DNA damage in the rat lung induced by intratracheal instillation and inhalation of nanoparticles
    Yun-Shan Li; Yuko Ootsuyama; Yuya Kawasaki; Yasuo Morimoto; Toshiaki Higashi; Kazuaki Kawai
    Journal of Clinical Biochemistry and Nutrition, 2018, Reviewed, No invitation
    Lead
  • Perceived Stress, Depressive Symptoms, and Oxidative DNA Damage.
    Chisato Shimanoe; Megumi Hara; Yuichiro Nishida; Hinako Nanri; Mikako Horita; Yosuke Yamada; Yun-Shan Li; Hiroshi Kasai; Kazuaki Kawai; Yasuki Higaki; Keitaro Tanaka
    Psychosomatic medicine, Jan. 2018, Reviewed, No invitation
  • Biopersistence of NiO and TiO2 nanoparticles following intratracheal instillation and inhalation
    Takako Oyabu; Toshihiko Myojo; Byeong-Woo Lee; Takami Okada; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Yun-Shan Li; Kazuaki Kawai; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Kenji Kawaguchi; Takeshi Sasaki; Yasuo Morimoto
    International Journal of Molecular Sciences, Dec. 2017, Reviewed, No invitation
  • Antioxidant properties of green tea aroma in mice
    Yun-Shan Li; Yuya Kawasaki; Isao Tomita; Kazuaki Kawai
    JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, Jul. 2017, Reviewed, No invitation
    Lead
  • Status of Pregnant Women’s Mentaland Physical Stress and Influencesof Work
    Anan A; Yun-Shan Li; Tsuji M; Nagamatsu Y; Chou S; Toyofuku K; Nakatani J; Kawai K
    日本職業・災害医学会会誌 JJOMT, 2017, Reviewed, No invitation
  • Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives
    Taisuke Tomonaga; Hiroto Izumi; Yukiko Yoshiura; Toshihiko Myojo; Takako Oyabu; Byeong-Woo Lee; Takami Okada; Yunshan Li; Kazuaki Kawai; Toshiaki Higashi; Yasuo Morimoto
    BIOMED RESEARCH INTERNATIONAL, 2017, Reviewed, No invitation
  • Comparison of Blueberry (Vaccinium spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human
    Kim M; Na H; Kasai H; Kawai K; Yun-Shan Li; Yang M
    J Cancer Prev, 2017, Reviewed, No invitation
  • Intensity-specific effect of physical activity on urinary levels of 8-hydroxydeoxyguanosine in middle-aged Japanese
    Megumi Hara; Yuichiro Nishida; Chisato Shimanoe; Yasuko Otsuka; Hinako Nanri; Jun Yasukata; Nobuyuki Miyoshi; Yosuke Yamada; Mikako Horita; Kazuaki Kawai; Yun-Shan Li; Jun Kasai; Hiroshi Kasai; Yasuki Higaki; Keitaro Tanaka
    CANCER SCIENCE, Nov. 2016, Reviewed, No invitation
  • Urinary 1-hydroxypyrene and 8-hydroxydeoxyguanosine Levels among Coke-oven Workers for 2 Consecutive Days
    Thi-To-Uyen Nguyen; Shoko Kawanami; Kazuaki Kawai; Hiroshi Kasai; Yun-Shan Li; Jinro Inoue; Le Tran Ngoan; Seichi Horie
    JOURNAL OF OCCUPATIONAL HEALTH, May 2014, Reviewed, No invitation
  • 8-Hydroxyguanine in urine and serum as an oxidative stress marker: Effects of diabetes and aging
    Yun-Shan Li; Ming-Fen Song; Hiroshi Kasai; Kazuaki Kawai
    Journal of UOEH, Jun. 2013, Reviewed, No invitation
    Lead
  • Free radical-mediated cytosine C-5 methylation triggers epigenetic changes during carcinogenesis
    Hiroshi Kasai; Kazuaki Kawai; Yun-Shan Li
    Biomolecular Concepts, Jun. 2013, Reviewed, No invitation
  • Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2 '-deoxyguanosine
    Lars Barregard; Peter Moller; Trine Henriksen; Vilas Mistry; Gudrun Koppen; Pavel Rossner; Radim J. Sram; Allan Weimann; Henrik E. Poulsen; Robert Nataf; Roberta Andreoli; Paola Manini; Tim Marczylo; Patricia Lam; Mark D. Evans; Hiroshi Kasai; Kazuaki Kawai; Yun-Shan Li; Kazuo Sakai; Rajinder Singh; Friederike Teichert; Peter B. Farmer; Rafal Rozalski; Daniel Gackowski; Agnieszka Siomek; Guillermo T. Saez; Concha Cerda; Karin Broberg; Christian Lindh; Mohammad Bakhtiar Hossain; Siamak Haghdoost; Chiung-Wen Hu; Mu-Rong Chao; Kuen-Yuh Wu; Hilmi Orhan; Nilufer Senduran; Raymond J. Smith; Regina M. Santella; Yali Su; Czarina Cortez; Susan Yeh; Ryszard Olinski; Steffen Loft; Marcus S. Cooke
    ANTIOXIDANTS & REDOX SIGNALING, Jun. 2013, Reviewed, No invitation
  • Generation and threshold level of 8-OHdG as oxidative DNA damage elicited by low dose ionizing radiation
    Yun-Shan Li; Ming-Fen Song; Hiroshi Kasai; Kazuaki Kawai
    Genes and Environment, 2013, Reviewed, No invitation
    Lead
  • Analyses of 8-methyldeoxyadenosine and 8-methyldeoxyguanosine as markers of free radical-mediated DNA methylation in mouse
    Hiroshi Kasai; Kazuaki Kawai; Ming-Fen Song; Yun-Shan Li; Tomomi Hattori; Tomonari Matsuda
    Genes and Environment, 2013, Reviewed, No invitation
  • Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice
    Ming-Fen Song; Yun-Shan Li; Hiroshi Kasai; Kazuaki Kawai
    JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, May 2012, Reviewed, No invitation
  • Methionine sulfoxide stimulates hepatocarcinogenesis in non-alcoholic steatohepatitis (NASH) mouse: Possible role of free radical-mediated DNA methylation
    Kazuaki Kawai; Yun-Shan Li; Ming-Fen Song; Yuko Ootsuyama; Anna Kakehashi; Hideki Wanibuchi; Akira Ootsuyama; Toshiyuki Norimura; Hiroshi Kasai
    Genes and Environment, 2012, Reviewed, No invitation
  • Exposure to polycyclic aromatic hydrocarbons, arsenic and environmental tobacco smoke, nutrient intake, and oxidative stress in Japanese preschool children
    Takuya Mori; Jun Yoshinaga; Kei Suzuki; Miho Mizoi; Shu-ichi Adachi; Hiroaki Tao; Tetsuya Nakazato; Yun-Shan Li; Kazuaki Kawai; Hiroshi Kasai
    SCIENCE OF THE TOTAL ENVIRONMENT, Jul. 2011, Reviewed, No invitation
  • DNA methylation at the C-5 position of cytosine by a methyl radical: A link between environmental agents and epigenetic change
    Hiroshi Kasai; Kazuaki Kawai; Yun-Shan Li
    Genes and Environment, 2011, Reviewed, No invitation
  • DNA Modifications by the omega-3 Lipid Peroxidation-Derived Mutagen 4-Oxo-2-hexenal in Vitro and Their Analysis in Mouse and Human DNA
    Kazuaki Kawai; Pei-Hsin Chou; Tomonari Matsuda; Masaaki Inoue; Kaisa Aaltonen; Kirsti Savela; Yoshikazu Takahashi; Hikaru Nakamura; Tomoyuki Kimura; Takumi Watanabe; Ryuichi Sawa; Kazuyuki Dobashi; Yun-Shan Li; Hiroshi Kasai
    CHEMICAL RESEARCH IN TOXICOLOGY, Mar. 2010, Reviewed, No invitation
  • DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications
    Kazuaki Kawai; Yun-Shan Li; Ming-Fen Song; Hiroshi Kasai
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jan. 2010, Reviewed, No invitation
  • Urea, the most abundant component in urine, cross-reacts with a commercial 8-OH-dG ELISA kit and contributes to overestimation of urinary 8-OH-dG
    Ming-Fen Song; Yun-Shan Li; Yuko Ootsuyama; Hiroshi Kasai; Kazuaki Kawai; Masanori Ohta; Yasumasa Eguchi; Hiroshi Yamato; Yuki Matsumoto; Rie Yoshida; Yasutaka Ogawa
    FREE RADICAL BIOLOGY AND MEDICINE, Jul. 2009, Reviewed, No invitation
  • Biological Indicators of Lifestyle-related Diseases and Urinary 8-Hydroxydeoxyguanosine Level
    Ikegami Kazunori; Arakomo Yuko; Suzuki Kiyomi; Tahara Hiroyuki; Yamada Tatsuji; Moriyama Kouji; Mafune Kosuke; Hiro Hisanori; Nagata Shoji; Li Yunshan; Kasai Hiroshi
    Asian Pacific Journal of Disease Management, 2009
  • Analysis of 8-OH-dG and 8-OH-Gua as biomarkers of oxidative stress
    Kasai H; Kawai K; Yun-Shan Li
    Genes and Environment, 2008, Reviewed, No invitation
  • Increase of Urinary 8-OH-dG Levels after Administration of a Vitamin-deficient Diet and a Sweet Beverage
    Yun-Shan Li; Kazuaki Kawai; Hiroshi Kasai
    Genes and Environment, 2007, Reviewed, No invitation
    Lead
  • Accurate Measurement of 8-OH-dG and 8-OH-Gua in Mouse DNA, Urine and Serum: Effects of X-ray Irradiation
    Kazuaki Kawai; Yun-Shan Li; Hiroshi Kasai
    Genes and Environment, 2007, Reviewed, No invitation
  • A hemolysin of Vibrio mimicus (VMH) stimulates cells to produce ATP and cyclic AMP which appear to be secretory mediators
    YS Li; K Okamoto; E Takahashi; S Miyoshi; S Shinoda; T Tsuji; Y Fujii
    MICROBIOLOGY AND IMMUNOLOGY, 2005, Reviewed, No invitation
    Lead
  • Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives.
    Tomonaga Taisuke, Izumi Hiroto, Yoshiura Yukiko, Myojo Toshihiko, Oyabu Takako, Lee Byeong-Woo, Okada Takami, Li Yunshan, Kawai Kazuaki, Higashi Toshiaki, Morimoto Yasuo
    BioMed research international, Jan. 2017, Reviewed, No invitation
  • Free radical-mediated cytosine C-5 methylation triggers epigenetic changes during carcinogenesis
    Kasai Hiroshi, Kawai Kazuaki, Li Yun-Shan
    Biomolecular Concepts, Jun. 2013, Reviewed, Null
    Last
  • Free radical-mediated cytosine C-5 methylation triggers epigenetic changes during carcinogenesis
    Hiroshi Kasai, Kazuaki Kawai, Yun-Shan Li
    Biomolecular concepts, Feb. 2013, Reviewed, Null
    Last
  • DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modification
    Kawai Kazuaki, Li Yun-Shan, Song Ming-Fen, Kasai Hiroshi
    Bioorganic & Medicinal Chemistry Letters, 2010, Reviewed, Null
  • Intensity-specific effect of physical activity on urinary levels of 8-hydroxydeoxyguanosine in middle-aged Japanese.
    Hara Megumi, Nishida Yuichiro, Shimanoe Chisato, Otsuka Yasuko, Nanri Hinako, Yasukata Jun, Miyoshi Nobuyuki, Yamada Yosuke, Horita Mikako, Kawai Kazuaki, Li Yun-Shan, Kasai Jun, Kasai Hiroshi, Higaki Yasuki, Tanaka Keitaro
    Cancer science, Nov. 2016, Reviewed, No invitation
  • DNA modifications by the ω-3 lipid peroxidation-derived mutagen 4-oxo-2-hexenal in vitro and their analysis in mouse and human DNA
    Kawai Kazuaki, Chou Pei-Hsin, Matsuda Tomonari, Inoue Masaaki, Aaltonen Kaisa, Savela Kirsti, Takahashi Yoshikazu, Nakamura Hikaru, Kimura Tomoyuki, Watanabe Takumi, Sawa Ryuichi, Dobashi Kazuyuki, Li Yun-Shan, Kasai Hiroshi
    Chemical research in toxicology, 2010, Reviewed, Null
  • Urea, the most abundant component in urine, cross-reacts with a commercial 8-OH-dG ELISA kit and contributes to overestimation of urinary 8-OH-dG.
    Song Ming-Fen, Li Yun-Shan, Ootsuyama Yuko, Kasai Hiroshi, Kawai Kazuaki, Ohta Masanori, Eguchi Yasumasa, Yamato Hiroshi, Matsumoto Yuki, Yoshida Rie, Ogawa Yasutaka
    Free radical biology & medicine, Jul. 2009, Reviewed, No invitation
  • Generation and threshold level of 8-OHdG as oxidative DNA damage elicited by low dose ionizing radiation
    Li Yun-Shan, Song Ming-Fen, Kasai Hiroshi and Kawai Kazuaki
    Genes and Environment, 2013, Reviewed, No invitation
    Lead
  • Analyses of 8-methyldeoxyadenosine and 8-methyldeoxyguanosine as markers of free radical-mediated DNA methylation in mouse
    Kasai Hiroshi, Kawai Kazuaki, Song Ming-Fen, Li Yun-Shan, Hattori Tomomi, Matsuda Tomonari
    Genes and Environment, 2013, Reviewed, Null
  • DNA methylation at the C-5 position of cytosine by a methyl radical: a link between environmental agents and epigenetic change
    Kasai Hiroshi, Kawai Kazuaki, Li Yun-Shan
    Genes and Environment, 2011, Reviewed, Null
    Last
  • Analysis of 8-OH-dG and 8-OH-Gua as biomarkers of oxidative stress.
    Kasai Hiroshi, Kawai Kazuaki, Li Yun-Shan
    Genes and Environment, 2008, Reviewed, Null
    Last
  • Increase of urinary 8-OH-dG levels after administration of a vitamin-deficient diet and a sweet beverage.
    Li Yun-Shan, Kawai Kazuaki, Kasai Hiroshi
    Genes and Environment, 2007, Reviewed, No invitation
    Lead
  • Accurate measurement of 8-OH-dG and 8-OH-Gua in mouse DNA, urine and serum: effects of X-ray irradiation
    Kawai Kazuaki, Li Yun-Shan, Kasai Hiroshi
    Genes and Environment, 2007, Reviewed, Null
  • Effects of smoking cessation on biological monitoring markers in urine.
    Kawasaki Yuya, Li Yun-Shan, Ootsuyama Yuko, Nagata Kazuhiko, Yamato Hiroshi, Kawai Kazuaki
    Genes and environment, Sep. 2020, Reviewed, No invitation
  • Measurement of 8-hydroxyguanine as an oxidative stress biomarker in saliva by HPLC-ECD.
    Kawai Kazuaki, Kasai Hiroshi, Li Yun-Shan, Kawasaki Yuya, Watanabe Shintaro, Ohta Masanori, Honda Toru, Yamato Hiroshi
    Genes and environment : the official journal of the Japanese Environmental Mutagen Society, Apr. 2018, Reviewed, No invitation
  • Biopersistence of NiO and TiO₂ Nanoparticles Following Intratracheal Instillation and Inhalation.
    Oyabu Takako, Myojo Toshihiko, Lee Byeong-Woo, Okada Takami, Izumi Hiroto, Yoshiura Yukiko, Tomonaga Taisuke, Li Yun-Shan, Kawai Kazuaki, Shimada Manabu, Kubo Masaru, Yamamoto Kazuhiro, Kawaguchi Kenji, Sasaki Takeshi, Morimoto Yasuo
    International journal of molecular sciences, Dec. 2017, Reviewed, No invitation
  • Comparison of Blueberry (Vaccinium spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human
    Kim Minju, Na Hyunkyung, Kasai Hiroshi, Kawai Kazuaki, Li Yun-Shan, Yang Mihi
    Journal of Cancer Prevention, Sep. 2017, Reviewed, No invitation
  • Assessment of exposure and DNA damage from second-hand smoke using potential biomarker in urine: cigarettes and heated tobacco products
    Yuya Kawasaki, Yun-Shan Li, Yuko Ootsuyama, Koichi Fujisawa, Hisamitsu Omori, Ayumi Onoue, Kenichi Kubota, Toshimi Yoshino, Yoshio Nonami, Minoru Yoshida, Hiroshi Yamato, and Kawai Kazuaki
    Journal of Clinical Biochemistry and Nutrition, May 2023, Reviewed, Null
  • 8-hydroxyguanine in urine and serum as an oxidative stress marker: effects of diabetes and aging.
    Li Yun-Shan, Song Ming-Fen, Kasai Hiroshi, Kawai Kazuaki
    Journal of UOEH, Jun. 2013, Reviewed, No invitation
    Lead
  • Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model.
    Mano Yosuke, Tsukamoto Manabu, Wang Ke-Yong, Nabeshima Takayuki, Kosugi Kenji, Tajima Takafumi, Yamanaka Yoshiaki, Suzuki Hitoshi, Kawasaki Makoto, Nakamura Eiichiro, Zhou Qian, Azuma Kagaku, Nakashima Tamiji, Tamura Yuki, Kozaki Karina, Nakazato Koichi, Li Yun-Shan, Kawai Kazuaki, Yatera Kazuhiro, Sakai Akinori
    Journal of bone and mineral metabolism, Nov. 2022, Reviewed, No invitation
  • Urinary biomarkers for secondhand smoke and heated tobacco products exposure.
    Kawasaki Yuya, Li Yun-Shan, Watanabe Sintaroo, Ootsuyama Yuko, Kawai Kazuaki
    Journal of clinical biochemistry and nutrition, Jul. 2021, Reviewed, No invitation
  • Diurnal and day-to-day variation of urinary oxidative stress marker 8-hydroxy-2'-deoxyguanosine.
    Li Yun-Shan, Kawasaki Yuya, Watanabe Sintaroo, Ootsuyama Yuko, Kasai Hiroshi, Kawai Kazuaki
    Journal of clinical biochemistry and nutrition, Jan. 2021, Reviewed, No invitation
    Lead
  • Oxidative DNA damage in the rat lung induced by intratracheal instillation and inhalation of nanoparticles.
    李云善, 大津山祐子, 川﨑祐也, 森本泰夫, 東敏昭, 河井一明
    Journal of clinical biochemistry and nutrition, May 2018, Reviewed, No invitation
    Lead
  • Antioxidant properties of green tea aroma in mice.
    Li Yun-Shan, Kawasaki Yuya, Tomita Isao, Kawai Kazuaki
    Journal of clinical biochemistry and nutrition, Jul. 2017, Reviewed, No invitation
    Lead
  • Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice.
    Song Ming-Fen, Li Yun-Shan, Kasai Hiroshi, Kawai Kazuaki
    Journal of clinical biochemistry and nutrition, May 2012, Reviewed, No invitation
  • Health examination results and work environment factors affecting urinary 8-hydroxy-2'-deoxyguanosine levels.
    Watanabe Sintaroo, Li Yun-Shan, Kawasaki Yuya, Ootsuyama Yuko, Kawai Kazuaki
    Journal of occupational health, Mar. 2021, Reviewed, No invitation
  • Pilot clinical study of ascorbic acid treatment in cardiac catheterization.
    Sun Lue, Igarashi Tomonori, Tetsuka Ryoya, Li Yun-Shan, Kawasaki Yuya, Kawai Kazuaki, Hirakawa Haruhisa, Tsuboi Koji, Nakamura Asako J, Moritake Takashi
    Journal of radiation research, Oct. 2019, Reviewed, Null
  • A hemolysin of Vibrio mimicus (VMH) stimulates cells to produce ATP and cyclic AMP which appear to be secretory mediators.
    Li Yunshan, Okamoto Keinosuke, Takahashi Eizo, Miyoshi Shin-Ichi, Shinoda Sumio, Tsuji Takao, Fujii Yoshio
    Microbiology and immunology, 2005, Reviewed, Null
    Lead
  • The Association between Oxidative Balance Score and Urinary Levels of 8-Hydroxydeoxyguanosine among Japanese Adults
    Hinako Nanri, Megumi Hara, Yuichiro Nishida, Chisato Shimanoe, Yun-Shan Li,_x000D_ Hiroshi Kasai, Kazuaki Kawai, Yasuki Higaki, Keitaro Tanaka
    Nutrients, Oct. 2023, Reviewed, Null
  • Dietary non-enzymatic antioxidant capacity and DNA damage in a working population.
    Kashino Ikuko, Li Yun-Shan, Kawai Kazuaki, Nanri Akiko, Miki Takako, Akter Shamima, Kobayashi Satomi, Kasai Hiroshi, Mizoue Tetsuya
    Nutrition (Burbank, Los Angeles County, Calif.), Mar. 2018, Reviewed, Null
  • Leisure-time physical activity and DNA damage among Japanese workers.
    Kawakami Ryoko, Kashino Ikuko, Kasai Hiroshi, Kawai Kazuaki, Li Yun-Shan, Nanri Akiko, Higuchi Mitsuru, Mizoue Tetsuya
    PloS one, Feb. 2019, Reviewed, Null
  • Perceived Stress, Depressive Symptoms, and Oxidative DNA Damage.
    Shimanoe Chisato, Hara Megumi, Nishida Yuichiro, Nanri Hinako, Horita Mikako, Yamada Yosuke, Li Yun-Shan, Kasai Hiroshi, Kawai Kazuaki, Higaki Yasuki, Tanaka Keitaro
    Psychosomatic medicine, Jan. 2018, Reviewed, Null
  • Exposure to polycyclic aromatic hydrocarbons, arsenic and environmental tobacco smoke, nutrient intake, and oxidative stress in Japanese preschool children
    Mori Takuya, Yoshinaga Jun, Suzuki Kei, Mizoib Miho, Adachi Shu-ichi, Tao Hiroaki, Nakazato Tetsuya, Li Yun-Shan, Kawai Kazuaki, Kasai Hiroshi
    Science of the Total Environment, 2011, Reviewed, No invitation
  • Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7, 8-dihydro-2¢-deoxyguanosine
    Barregard Lars, Møller Peter, Henriksen Trine,et al.,Kasai Hiroshi, Kawai Kazuaki, Li Yun-Shan(18 in 44) et al.
    antioxidant & Redox Signaling, Jun. 2013, Reviewed, No invitation
  • Effect of physical appearance and maturity on yield and quality indark sun-cured tobacco
    Piao S-L,Li H-L,Jin J-S,Jin Z-J,Li Yun-Shan,An J-H
    Journal of Chinese Tobacco, Aug. 2000, Reviewed, No invitation
  • Studies on charging laws of main chemical components in sun-cured tobacco
    Li H-L,Piao S-L,Li Yun-Shan,Jin J-S,Lu Z-E
    Chinese Tobacco Science, Feb. 1998, Reviewed, No invitation
  • Growth of regularity of shade-cultivated Codonopsis lameolata
    Li Hu-Lin, Li Yun-Shan, An Jin-Hua, Li Lian-Ha, Piao Shi-Ling
    Journal of Jilin Agricultural University, Oct. 2003, Reviewed, No invitation
  • Effect of Different Amount Combinations of Fertilizers on Output Value of Flue-cure Tobacco
    Piao S-L,Jin J-S,An J-H,Li L-H,Li Yun-Shan,Su Y-M
    Journal of Jilin Agricultural University, Jan. 2003, Reviewed, No invitation
  • Agriculture and seed production condition in Poland
    Li Yun-Shan,An J-H,Piao J-Z
    Journal of Jilin Agricultural Science, Jun. 2002, Reviewed, No invitation
    Lead, Corresponding
  • Esterase isozymic electrophoregrams of rice stabilizing lines from final generation between rice and wild rice
    Li Yun-Shan,Piao S-L,Piao H-M,Jiang J-J,Jin J-S
    Journal of Jilin Agricultural Science, Feb. 2001, Reviewed, No invitation
    Lead
  • Amplification of PCR in identification of intergeneric hybrids between Anthurium andraeanum and Spathiphyllum wallussi
    Li Yun-Shan,Elzibieta Zenkteler, Andrzej Pacak, Li L-H,Li H-L
    Journal of Anhui Agricultural University, Aug. 2002, Reviewed, No invitation
    Lead, Corresponding
  • Contents change of N, P, K during the vegetative growth in Platycodon grandiflorum
    Li L-H, Li H-L, Li Yun-Shan, Su Y-M, Yang Z
    Journal of Agricultural Science Yanbian University, Jun. 2003, Reviewed, No invitation
  • Morphology and germination of Codonopsis lameolata seed
    Li Yun-Shan, Li H-L, An J-H, Li L-H, Su Y-M
    Journal of Agricultural Science Yanbian University, Jun. 2003, Reviewed, No invitation
    Lead, Corresponding
  • Analysis of curing effect on Korean coal fuel curer
    Li H-L, Piao S-L, Li Yun-Shan, Li L-H
    Journal of Agricultural Science Yanbian University, Apr. 2003, Reviewed, No invitation
  • Effect of Wotu compound fertilizer in the flue-cured tobacco production
    Jin H-L,Piao S-L,Li Yun-Shan,Jin S-Y,Jin H-S
    Journal of Agricultural Science Yanbian University, Aug. 2002, Reviewed, No invitation
  • Peroxidase isozymic electrophoregrams of rice stabilizing lines from final generation between rice and wild rice
    Li Yun-Shan,Piao S-L,Piao H-M,Jiang J-J,Piao M-Y
    Journal of Agricultural Science Yanbian University, Jun. 2000, Reviewed, No invitation
    Lead
  • Effect of spraying SHEN NONG YE on flue-cured tobacco yield and quality
    Piao S-L,Jin J-S,Xu D-Y,Jin H-L,Li Yun-Shan
    Journal of Agricultural Science Yanbian University, Jun. 2000, Reviewed, No invitation
    Last
  • Study on infrared coating’s application effect in flue-cured tobacco
    Piao S-L,Li Yun-Shan,Jin J-S,An J-H,Jin C-L
    Journal of Agricultural Science Yanbian University, Aug. 1999, Reviewed, No invitation
  • Effect of application “JINBISHENG” series fertilizer on flue-cured tobacco Production
    Jin J-S,Piao S-L,Li Y-S,Jiang H,Piao Y-H
    Journal of Agricultural Science Yanbian University, Jun. 1999, Reviewed, No invitation
  • Brief account of scale management in plant tobacco product
    Li Yun-Shan,Piao S-L,Jin J-S
    Journal of Agricultural Science Yanbian University, Feb. 1999, Reviewed, No invitation
    Lead
  • Application of product technology of high quality tobacco in Jilin East
    Jin J-S,Piao S-L,An J-H,Lu Z-E,Li Yun-Shan
    Journal of Agricultural Science Yanbian University, Aug. 1998, Reviewed, No invitation
    Last
  • Preliminary analysis on main character heterosis of flue-cured tobacco
    Lu Z-E,Li H-L,Piao S-L,Jin J-S,Li Yun-Shan
    Journal of Agricultural Science Yanbian University, Aug. 1997, Reviewed, No invitation
    Last
  • Study on change regular pattern of lesf’s chemical composition in the period of sun-cured tobacco modulation
    Piao S-L,Li H-L,Li Yun-Shan,Lu Z-E,Jin J-S
    Journal of Agricultural Science Yanbian University, Apr. 1995, Reviewed, No invitation
  • Urinary 1-hydroxypyrene and 8-hydroxydeoxyguanosine levels among coke-oven workers for 2 consecutive days.
    Nguyen Thi-To-Uyen, Kawanami Shoko, Kawai Kazuaki, Kasai Hiroshi, Li Yun-Shan, Inoue Jinro, Ngoan Le Tran, Horie Seichi
    Journal of occupational health, 2014, Null, Null
■ Books and other publications
  • Low-Dose Radiation Effects on Animals and Ecosystems II 15 Years after the Fukushima Nuclear Accident
    Kazuaki Kawai; Koichi Fujisawa; Yuko Ootsuyama; Masatoshi Suzuki; Yun-Shan Li; Manabu Fukumoto; Hiroshi Kasai, Contributor, Chapter 16 Assessment of Oxidative DNA Damage in the Affected Cattle After the Fukushima Daiichi Nuclear Power Plant Accident
    Springer Nature Singapore Pte Ltd., May 2026
    9789819555581
  • 産業医学における酸化的DNA損傷のバイオマーカー
    李云善, Single work
    公益財団法人 産業医学振興財団, Mar. 2021