[Factors that contribute to the death/severity and onset of COVID-19 infection in working generation: Investigation of general health examination items by narrative review].
Yasuo Morimoto; Hidenori Higashi; Hiroto Izumi; Taisuke Tomonaga; Chinatsu Nishida; Hiroshi Yamato; Hisashi Eguchi; Shoko Kawanami; Katsunori Suzuki; Kazuhiro Yatera; Akinori Nakata
Sangyo eiseigaku zasshi = Journal of occupational health, Jan. 2026

Polyacrylic acid, but not polyethylene glycol, induces metabolic reprogramming linked to pulmonary fibrosis in rats.
Taisuke Tomonaga; Hiroto Izumi; Chinatsu Nishida; Kazuma Sato; Yuiko Nakamura; Shinya Morimoto; Toshiki Morimoto; Yasuyuki Higashi; Hidenori Higashi; Midori Iida; Takuma Kojima; Kazuo Sakurai; Akihiro Moriyama; Jun-Ichi Takeshita; Kazuhiro Yatera; Yasuo Morimoto
Scientific reports, Dec. 2025

[Preventive measures against infections, including viruses in the workplace].
Yasuo Morimoto; Hidenori Higashi; Hiroto Izumi; Taisuke Tomonaga; Chinatsu Nishida; Hiroshi Yamato; Hisashi Eguchi; Shoko Kawanami; Katsunori Suzuki; Kazuhiro Yatera
Sangyo eiseigaku zasshi = Journal of occupational health, Nov. 2025

Antidepressants Target the ST3GAL5-GM3 Lipid Pathway to Suppress Microglial Inflammation.
Gaku Hayasaki; Hiroto Izumi; Yasuo Morimoto; Reiji Yoshimura
International journal of molecular sciences, Oct. 2025

有機高分子化合物の架橋度の違いが及ぼす肺胞上皮細胞傷害の検討
佐藤 和真; 友永 泰介; 和泉 弘人; 西田 千夏; 川合 直紀; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2025

化学物質の職業病発症リスクを有害性とばく露に分類して実施する労働衛生管理
森本 泰夫; 友永 泰介; 和泉 弘人; 佐藤 和真; 中村 佑生子; 西田 千夏; 東 秀憲
産業衛生学雑誌, Apr. 2025

有機高分子化合物のpHの違いが及ぼす肺障害性の検討
中村 佑生子; 友永 泰介; 和泉 弘人; 西田 千夏; 佐藤 和真; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2025

アクリル酸系ポリマーによる酸化ストレス応答と細胞毒性評価に関する解析
和泉 弘人; 西田 千夏; 友永 泰介; 東 泰幸; 森本 俊規; 佐藤 和真; 中村 佑生子; 東 秀憲; 森本 泰夫
産業衛生学雑誌, Apr. 2025

アクリル酸ポリマーによる肺障害性の解明 肺胞マクロファージの遺伝子発現変化の観察
友永 泰介; 和泉 弘人; 西田 千夏; 佐藤 和真; 中村 佑生子; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2025

じん肺診断における電子顕微鏡を用いた肺組織の元素分析の有用性
西田 千夏; 丈達 陽順; 友永 泰介; 和泉 弘人; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2025

Comparison of lung disorders following intratracheal instillation of polystyrene microplastics with different surface functional groups.
Taisuke Tomonaga; Hidenori Higashi; Hiroto Izumi; Chinatsu Nishida; Kazuma Sato; Yuiko Nakamura; Toshiki Morimoto; Yasuyuki Higashi; Takuma Kojima; Kazuo Sakurai; Kazuhiro Yatera; Yasuo Morimoto
Journal of occupational health, Feb. 2025

The degree of cross-linking of polyacrylic acid affects the fibrogenicity in rat lungs.
Taisuke Tomonaga; Hiroto Izumi; Chinatsu Nishida; Kazuma Sato; Yuiko Nakamura; Toshiki Morimoto; Yasuyuki Higashi; Ke-Yong Wang; Hidenori Higashi; Takuma Kojima; Kazuo Sakurai; Jun-Ichi Takeshita; Akihiro Moriyama; Kei Yamasaki; Kazuhiro Yatera; Yasuo Morimoto
Scientific reports, Jan. 2025

Adverse effects of nanoparticles on humans.
Yasuo Morimoto; Hiroto Izumi; Taisuke Tomonaga; Chinatsu Nishida; Hidenori Higashi
Journal of occupational health, Jan. 2025

Development of a new alternative method to inhalation exposure: intratracheal instillation studies using molecular dispersion
Toshiki Morimoto; Chinatsu Nishida; Hiroto Izumi; Taisuke Tomonaga; Kazuma Sato; Yasuyuki Higashi; Ke-Yong Wang; Takuma Kojima; Kazuo Sakurai; Akihiro Moriyama; Jun-ichi Takeshita; Kei Yamasaki; Hidenori Higashi; Kazuhiro Yatera; Yasuo Morimoto
Environmental Health and Preventive Medicine, 2025

Inhalation exposure to cross-linked polyacrylic acid induces pulmonary disorders.
Yasuyuki Higashi; Chinatsu Nishida; Hiroto Izumi; Kazuma Sato; Naoki Kawai; Taisuke Tomonaga; Toshiki Morimoto; Kei Yamasaki; Ke-Yong Wang; Hidenori Higashi; Akihiro Moriyama; Jun-Ichi Takeshita; Takuma Kojima; Kazuo Sakurai; Kazuhiro Yatera; Yasuo Morimoto
Toxicology, Jan. 2025

アクリル酸系高分子化合物の肺障害における物理化学的特性の影響
友永 泰介; 和泉 弘人; 川合 直紀; 佐藤 和真; 西田 千夏; 東 秀憲; 森本 俊規; 東 泰幸; 矢寺 和博; 森本 泰夫
日本肺サーファクタント・界面医学会雑誌, Oct. 2024

Investigation of pulmonary inflammatory responses following intratracheal instillation of and inhalation exposure to polypropylene microplastics.
Taisuke Tomonaga; Hidenori Higashi; Hiroto Izumi; Chinatsu Nishida; Naoki Kawai; Kazuma Sato; Toshiki Morimoto; Yasuyuki Higashi; Kazuhiro Yatera; Yasuo Morimoto
Particle and fibre toxicology, Aug. 2024

Intratracheal instillation of polyacrylic acid induced pulmonary fibrosis with elevated transforming growth factor-β1 and connective tissue growth factor.
Yasuyuki Higashi; Chinatsu Nishida; Taisuke Tomonaga; Hiroto Izumi; Naoki Kawai; Toshiki Morimoto; Kanako Hara; Kei Yamasaki; Akihiro Moriyama; Jun-Ichi Takeshita; Ke-Yong Wang; Hidenori Higashi; Ryohei Ono; Kazuki Sumiya; Kazuo Sakurai; Kazuhiro Yatera; Yasuo Morimoto
Toxicology, Aug. 2024

うつ病における重症度マーカーとしての血清由来細胞外小胞内miRNAの有用性
和泉 弘人; 船田 碧; 友永 泰介; 森本 泰夫
産業衛生学雑誌, Apr. 2024

アクリル酸系ポリマーの肺障害性に及ぼす分子量の影響としきい値の推定
西田 千夏; 和泉 弘人; 佐藤 和真; 川合 直紀; 森本 俊規; 東 泰幸; 友永 泰介; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2024

マイクロプラスチックの肺障害性評価 ラットへのポリプロピレンの気管内注入試験
友永 泰介; 和泉 弘人; 西田 千夏; 川合 直紀; 佐藤 和真; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2024

有機高分子化合物の架橋度の違いが及ぼす肺障害性の検討
佐藤 和真; 友永 泰介; 和泉 弘人; 西田 千夏; 川合 直紀; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2024

架橋型アクリル酸系水溶性高分子化合物による肺炎症と酸化ストレスの関連
川合 直紀; 和泉 弘人; 友永 泰介; 西田 千夏; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2024

ラットを用いたアクリル酸系ポリマーの肺線維化の検討
東 泰幸; 西田 千夏; 佐藤 和真; 川合 直紀; 森本 俊規; 友永 泰介; 原 可奈子; 山崎 啓; 和泉 弘人; 森本 泰夫; 矢寺 和博
日本呼吸器学会誌, Mar. 2024

アクリル酸系水溶性高分子化合物の気管内注入によるラット肺の小胞体ストレスの検討
森本 俊規; 西田 千夏; 友永 泰介; 和泉 弘人; 佐藤 和真; 川合 直紀; 東 泰幸; 山崎 啓; 森本 泰夫; 矢寺 和博
日本呼吸器学会誌, Mar. 2024

有機高分子化合物の肺障害性の検討
東 泰幸; 西田 千夏; 佐藤 和真; 川合 直紀; 森本 俊規; 先成 このみ; 友永 泰介; 山崎 啓; 和泉 弘人; 東 秀憲; 森本 泰夫; 矢寺 和博
産業医科大学雑誌, Mar. 2024

マイクロプラスチックの健康影響に関する現状把握
角田 碧空; 国場 大樹; 末吉 達; 篠田 遼; 友永 泰介; 川合 直紀; 佐藤 和真; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2024

CRISPR-Cas9を使用したノックアウトマウスを作製するためのgRNAデザイン
篠田 遼; 国場 大樹; 末吉 達; 角田 碧空; 友永 泰介; 川合 直紀; 佐藤 和真; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2024

HL60細胞で発現するミエロペルオキシダーゼの構造解析
国場 大樹; 末吉 達; 角田 碧空; 篠田 遼; 友永 泰介; 川合 直紀; 佐藤 和真; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2024

The effects of endoplasmic reticulum stress via intratracheal instillation of water-soluble acrylic acid polymer on the lungs of rats
Toshiki Morimoto; Hiroto Izumi; Taisuke Tomonaga; Chinatsu Nishida; Naoki Kawai; Yasuyuki Higashi; wang keyong; Ryohei Ono; Kazuki Sumiya; Kazuo Sakurai; Akihiro Moriyama; Jun-ichi Takeshita; Kei Yamasaki; Kazuhiro Yatera; Yasuo Morimoto
International Journal of Molecular Sciences, Mar. 2024, Reviewed

国内外の産業医学に関する文献紹介 有機高分子化合物の肺障害についての最近の知見
友永 泰介; 西田 千夏; 和泉 弘人; 森本 泰夫
産業医学ジャーナル, Jan. 2024

ラットを用いたポリプロピレン微粒子の肺障害性の評価
友永 泰介; 和泉 弘人; 川合 直紀; 佐藤 和真; 西田 千夏; 東 泰幸; 森本 俊規; 東 秀憲; 矢寺 和博; 森本 泰夫
大気環境学会年会講演要旨集, Sep. 2023

IL-6-Mediated Upregulated miRNAs in Extracellular Vesicles Derived from Lund Human Mesencephalic (LUHMES) Cells: Effects on Astrocytes and Microglia.
Kento Nishi; Hiroto Izumi; Taisuke Tomonaga; Chikage Nagano; Yasuo Morimoto; Seichi Horie
Biomolecules, Apr. 2023

in vitro試験による吸入性化学物質の肺有害性評価システムの開発
和泉 弘人; 友永 泰介; 西田 千夏; 森本 泰夫
産業衛生学雑誌, Apr. 2023

有機高分子化合物の架橋構造が及ぼす肺障害性の検討
友永 泰介; 和泉 弘人; 西田 千夏; 川合 直紀; 東 泰幸; 森本 俊規; 山崎 啓; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2023

有機高分子化合物による肺障害と物理化学的特性についての検討
西田 千夏; 和泉 弘人; 川合 直紀; 森本 俊規; 東 泰幸; 友永 泰介; 東 秀憲; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2023

有機高分子化合物の物理化学的特性の違いが肺障害性に及ぼす影響の検討
西田 千夏; 和泉 弘人; 友永 泰介; 川合 直紀; 東 泰幸; 森本 俊規; 山崎 啓; 矢寺 和博; 森本 泰夫
日本呼吸器学会誌, Mar. 2023

ラットを用いた架橋型アクリル酸系高分子化合物の肺障害性の検討
東 泰幸; 森本 泰夫; 西田 千夏; 友永 泰介; 和泉 弘人; 東 秀憲; 森本 俊規; 山崎 啓; 矢寺 和博
日本呼吸器学会誌, Mar. 2023

架橋型ポリアクリル酸の肺への有害性評価
西田 千夏; 和泉 弘人; 友永 泰介; 東 秀憲; 東 泰幸; 森本 俊規; 山崎 啓; 矢寺 和博; 森本 泰夫
産業医科大学雑誌, Mar. 2023

吸入性ナノプラスチックの生体影響 ポリスチレンナノ粒子の気管内注入試験
友永 泰介; 和泉 弘人; 川合 直紀; 西田 千夏; 東 泰幸; 森本 俊規; 矢寺 和博; 森本 泰夫
産業医科大学雑誌, Mar. 2023

ナノ粒子の有害性評価におけるラットとマウスのIn vivoデータ比較解析
芥川 侑大; 鹿島 功暉; 佐藤 蒼一郎; 岡田 琉伽; 友永 泰介; 川合 直紀; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2023

ネコカリシウイルスの粒子数と感染能力の関係
佐藤 蒼一郎; 芥川 侑大; 鹿島 功暉; 岡田 琉伽; 友永 泰介; 川合 直紀; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2023

Binding assay of human Dectin-1 variants for DNA/ β-glucan complex for active-targeting delivery of antisense DNA: Part II.
Kazuki Sumiya; Hiroto Izumi; Yoshiyuki Adachi; Shinichi Mochizuki; Kazuo Sakurai
Carbohydrate research, Jan. 2023, Reviewed

Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation
Chinatsu Nishida; Taisuke Tomonaga; Hiroto Izumi; Ke-Yong Wang; Hidenori Higashi; Toru Ishidao; Jun-ichi Takeshita; Ryohei Ono; Kazuki Sumiya; Shota Fujii; Shinichi Mochizuki; Kazuo Sakurai; Kei Yamasaki; Kazuhiro Yatera; Yasuo Morimoto
Particle and Fibre Toxicology, Dec. 2022, Reviewed

Crosslinked Structure of Polyacrylic Acid Affects Pulmonary Fibrogenicity in Rats
Taisuke Tomonaga; Chinatsu Nishida; Hiroto Izumi; Naoki Kawai; Ke-Yong Wang; Hidenori Higashi; Jun-Ichi Takeshita; Ryohei Ono; Kazuki Sumiya; Shota Fujii; Yuki Hata; Kazuo Sakurai; Toshiki Morimoto; Yasuyuki Higashi; Kei Yamasaki; Kazuhiro Yatera; Yasuo Morimoto
International Journal of Molecular Sciences, Nov. 2022

Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation
Chinatsu Nishida; Hiroto Izumi; Taisuke Tomonaga; Ke-Yong Wang; Hidenori Higashi; Jun-Ichi Takeshita; Ryohei Ono; Kazuki Sumiya; Shota Fujii; Yuki Hata; Kazuo Sakurai; Yasuyuki Higashi; Kei Yamasaki; Kazuhiro Yatera; Yasuo Morimoto
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Sep. 2022, Reviewed

ネコカリシウイルス誘導性の細胞変性とウイルス粒子数の解析
和泉 弘人; 友永 泰介; 西田 千夏; 東 泰幸; 森本 泰夫
産業衛生学雑誌, May 2022

気管内注入試験による有機粉じん肺障害の検討
西田 千夏; 和泉 弘人; 東 泰幸; 友永 泰介; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, May 2022

アスベストとシリカの気管内注入試験によるエクソソーム内包マイクロRNAの比較解析
友永 泰介; 和泉 弘人; 丸居 誉; 西田 千夏; 東 泰幸; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, May 2022

酸化タングステンナノ粒子の気管内注入によるラット肺への健康影響
丸居 誉; 友永 泰介; 和泉 弘人; 西田 千夏; 東 泰幸; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, May 2022

ラットを用いた架橋型アクリル酸系水溶性高分子化合物の肺障害性の検討
東 泰幸; 西田 千夏; 友永 泰介; 和泉 弘人; 森本 泰夫; 山崎 啓; 矢寺 和博
日本呼吸器学会誌, Apr. 2022

有機高分子化合物の肺炎症・線維化能の検討
西田 千夏; 森本 泰夫; 和泉 弘人; 友永 泰介; 東 泰幸; 矢寺 和博
日本呼吸器学会誌, Apr. 2022

Delivery of therapeutic oligonucleotides targeting Dectin-1 using quantized complexes
Kazuki Sumiya; Hiroto Izumi; Takuya Matsunaga; Motoko Tanaka; Kazuo Sakurai
Polymer Journal, Apr. 2022, Reviewed

ナノ材料の肺障害性を予測するバイオマーカーの有用性の検討
西田 千夏; 和泉 弘人; 友永 泰介; 竹下 潤一; 王 克よう; 山崎 啓; 矢寺 和博; 森本 泰夫
産業医科大学雑誌, Mar. 2022

不死化肺胞上皮細胞を用いたナノ粒子の肺有害性評価指標の開発
友永 泰介; 和泉 弘人; 西田 千夏; 東 泰幸; 森本 泰夫
産業医科大学雑誌, Mar. 2022

ラット型肺胞上皮細胞の単離法の検討
朝廣 鈴; 寺井 智果子; 加藤 卓; 辛島 晃至; 友永 泰介; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2022

In vitroで培養可能なラット肺胞マクロファージの形態、機能、遺伝子発現解析
加藤 卓; 辛島 晃至; 朝廣 鈴; 寺井 智果子; 友永 泰介; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2022

Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model
Taisuke Tomonaga; Hiroto Izumi; Chinatsu Nishida; Kaori Kato; Kazuhiro Yatera; Etsushi Kuroda; Yasuo Morimoto
Toxics, Jan. 2022

Pulmonary disorder induced by cross‐linked polyacrylic acid
Yasuyuki Higashi; Yasuo Morimoto; Chinatsu Nishida; Taisuke Tomonaga; Hiroto Izumi; Ke‐Yong Wang; Hidenori Higashi; Ryohei Ono; Kazuki Sumiya; Kazuo Sakurai; Kei Yamasaki; Kazuhiro Yatera
Journal of Occupational Health, Jan. 2022, Reviewed

Pulmonary toxicity of tungsten trioxide nanoparticles in an inhalation study and an intratracheal instillation study
Takashi Marui; Taisuke Tomonaga; Hiroto Izumi; Yukiko Yoshiura; Chinatsu Nishida; Hidenori Higashi; Ke‐Yong Wang; Miyako Shijo; Masaru Kubo; Manabu Shimada; Yasuo Morimoto
Journal of Occupational Health, Jan. 2022, Reviewed

Enhanced In-vitro Efficacy of Antisense Delivery by Use of Low-molecular Weight Polysaccharide/DNA Complex
Kazuki Sumiya; Hiroto Izumi; Shinichi Mochizuki; Kazuo Sakurai
Chemistry Letters, Jun. 2021, Reviewed

産業化学物質による産業現場の現状と実験・疫学研究の寄与 化学物質の発がん 特に肺腫瘍について種差とリスク評価の観点から
森本 泰夫; 西田 千夏; 友永 泰介; 和泉 弘人
産業衛生学雑誌, Apr. 2021

ナノ材料の有害性評価における血清中サーファクタントプロテインDの有用性
友永 泰介; 和泉 弘人; 丸居 誉; 西田 千夏; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2021

コルチゾールによる神経前駆細胞由来エクソソーム内包miRNAの発現変動
宮崎 洋介; 和泉 弘人; 西 健斗; 友永 泰介; 森本 泰夫; 堀江 正知
産業衛生学雑誌, Apr. 2021

健常者における細胞外小胞由来microRNAの発現プロファイル解析
和泉 弘人; 宮崎 洋介; 西 健斗; 田中 完; 友永 泰介; 堀江 正知; 森本 泰夫
産業衛生学雑誌, Apr. 2021

有機高分子化合物の肺への有害性の評価
西田 千夏; 和泉 弘人; 友永 泰介; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Apr. 2021

有機高分子化合物の肺への有害性の評価
西田 千夏; 和泉 弘人; 友永 泰介; 内村 圭吾; 矢寺 和博; 森本 泰夫
産業医科大学雑誌, Mar. 2021

吸入性粉じんの有害性評価における気管内吸入試験の検討
友永 泰介; 和泉 弘人; 西田 千夏; 森本 泰夫
産業医科大学雑誌, Mar. 2021

エクソソームの動態観察
上前 晃平; 木下 智貴; 工藤 大河; 新田 あゆ美; 友永 泰介; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2021

エクソソーム内包microRNAとストレス応答
和泉 弘人; 友永 泰介; 堀江 正知; 森本 泰夫
産業医科大学雑誌, Mar. 2021

水溶性高分子化合物による肺炎症の新たな評価方法の検討
上前 晃平; 木下 智貴; 工藤 大河; 新田 あゆ美; 友永 泰介; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2021

Pleural Plaques as a Predictive Imaging Marker for Cancer Screening in Asbestos-Exposed Subjects: Can Pleural Plaques Be a Tool beyond Estimating Past Asbestos Inhalation?
Yasuo Morimoto; Chinatsu Nishida; Taisuke Tomonaga; Hiroto Izumi
Respiratory Disease Series: Diagnostic Tools and Disease Managements, Feb. 2021

Lung disorders induced by respirable organic chemicals.
Yasuo Morimoto; Chinatsu Nishida; Taisuke Tomonaga; Hiroto Izumi; Kazuhiro Yatera; Kazuo Sakurai; Yangho Kim
Journal of occupational health, Jan. 2021, Reviewed

Examination of surfactant protein d as a biomarker for evaluating pulmonary toxicity of nanomaterials in rat
Taisuke Tomonaga; Hiroto Izumi; Yukiko Yoshiura; Chinatsu Nishida; Kazuhiro Yatera; Yasuo Morimoto
International Journal of Molecular Sciences, 2021

Binding assay of human Dectin-1 variants to DNA/β-glucan complex for active-targeting delivery of antisense DNA.
Nobuaki Fujiwara; Hiroto Izumi; Ryoma Kira; Yasuo Morimoto; Shinichi Mochizuki; Kazuo Sakurai
Carbohydrate research, Dec. 2020, Reviewed

Selection of microRNAs in extracellular vesicles for diagnosis of malignant pleural mesothelioma by in vitro analysis
TAKANOBU JOTATSU; HIROTO IZUMI; YASUO MORIMOTO; KAZUHIRO YATERA
Oncology Reports, Nov. 2020

Predictive Biomarkers for the Ranking of Pulmonary Toxicity of Nanomaterials.
Chinatsu Nishida; Hiroto Izumi; Taisuke Tomonaga; Jun-Ichi Takeshita; Ke-Yong Wang; Kei Yamasaki; Kazuhiro Yatera; Yasuo Morimoto
Nanomaterials (Basel, Switzerland), Oct. 2020, Reviewed

Induction of potent cell growth inhibition by schizophyllan/K-ras antisense complex in combination with gemcitabine
Shogo Sasaki; Hiroto Izumi; Yasuo Morimoto; Kazuo Sakurai; Shinichi Mochizuki
Bioorganic & Medicinal Chemistry, Sep. 2020, Reviewed

Assessment of Cytokine-Induced Neutrophil Chemoattractants as Biomarkers for Prediction of Pulmonary Toxicity of Nanomaterials
Taisuke Tomonaga; Hiroto Izumi; Takako Oyabu; Byeong-Woo Lee; Masaru Kubo; Manabu Shimada; Shingo Noguchi; Chinatsu Nishida; Kazuhiro Yatera; Yasuo Morimoto
NANOMATERIALS, Aug. 2020, Reviewed

毒性メカニズムの種差と化学物質のリスク評価 発がん影響の種差とリスク評価 肺腫瘍について
森本 泰夫; 西田 千夏; 友永 泰介; 和泉 弘人
産業衛生学雑誌, May 2020

アレルギー・免疫毒性における皮膚と呼吸器の接点か 職業性喘息などの呼吸機能障害
森本 泰夫; 西田 千夏; 友永 泰介; 和泉 弘人
産業衛生学雑誌, May 2020

MPOによるナノ材料の有害性評価 多層カーボンナノチューブ吸入ばく露試験の検討
友永 泰介; 和泉 弘人; 吉浦 由貴子; 丸居 誉; 西田 千夏; 明星 敏彦; 大藪 貴子; 岡田 崇顧; 森本 泰夫
産業衛生学雑誌, May 2020

ナノベシクル中のエクソソーム解析
和泉 弘人; 友永 泰介; 森本 泰夫
産業衛生学雑誌, May 2020

有機高分子化合物の肺への有害性の評価
西田 千夏; 内村 圭吾; 友永 泰介; 和泉 弘人; 矢寺 和博; 森本 泰夫
産業医科大学雑誌, Mar. 2020

エクソソーム内包マイクロRNAの精製と比較解析
山城 和也; 深川 悠太; 森元 伸哉; 友永 泰介; 和泉 弘人; 森本 泰夫
産業医科大学雑誌, Mar. 2020

UBE2L6 is Involved in Cisplatin Resistance by Regulating the Transcription of ABCB6.
Midori Murakami; Hiroto Izumi; Tomoko Kurita; Chiho Koi; Yasuo Morimoto; Kiyoshi Yoshino
Anti-cancer agents in medicinal chemistry, 2020

A Novel Polysaccharide Carrier for Targeted Delivery of Therapeutic Oligonucleotides to β-Glucan Receptors
Noriko Miyamoto; Shinichi Mochizuki; Nobuaki Fujiwara; Hiroto Izumi; Kazuo Sakurai
ACS Symposium Series, 2020

Long-term observation of pulmonary toxicity of toner with external additives following a single intratracheal instillation in rats
Taisuke Tomonaga; Hiroto Izumi; Yukiko Yoshiura; Takashi Marui; Ke-Yong Wang; Chinatsu Nishida; Kazuhiro Yatera; Yasuo Morimoto
Journal of Occupational Health, Jan. 2020

Inter-laboratory Comparison of Pulmonary Lesions Induced by Intratracheal Instillation of NiO Nanoparticle in Rats: Histopathological Examination Results
Senoh, Hideki; Kano, Hirokazu; Suzuki, Masaaki; Fukushima, Shoji; Oshima, Yutaka; Kobayashi, Toshio; Morimoto, Yasuo; Izumi, Hiroto; Ota, Yasufumi; Takehara, Hiroshi; Numano, Takamasa; Kawabe, Mayumi; Gamo, Masashi; Takeshita, Jun-ichi
Journal of Occupational Health, Jan. 2020, Reviewed, No invitation

The overexpression of peroxiredoxin-4 affects the progression of idiopathic pulmonary fibrosis.
Tetsuya Hanaka; Takashi Kido; Shingo Noguchi; Sohsuke Yamada; Hirotsugu Noguchi; Xin Guo; Aya Nawata; Ke-Yong Wang; Keishi Oda; Tsutomu Takaki; Hiroto Izumi; Hiroshi Ishimoto; Kazuhiro Yatera; Hiroshi Mukae
BMC pulmonary medicine, Dec. 2019, Reviewed, No invitation

悪性胸膜中皮腫細胞由来のエクソソーム内包マイクロRNA解析
和泉 弘人; 友永 泰介; 丸居 誉; 吉浦 由貴子; 森本 泰夫
産業衛生学雑誌, May 2019

ナノ材料の有害性評価におけるMPOの有用性 シリカ粒子気管内注入試験の検討
友永 泰介; 和泉 弘人; 吉浦 由貴子; 丸居 誉; 西田 千夏; 明星 敏彦; 大藪 貴子; 岡田 崇顧; 森本 泰夫
産業衛生学雑誌, May 2019

ナノ材料の有害性の早期予測のための新規バイオマーカーの検索 繊維状物質などについての検討
吉浦 由貴子; 和泉 弘人; 藤澤 有里; 西田 千夏; 丸居 誉; 友永 泰介; 森本 泰夫
産業医科大学雑誌, Mar. 2019

ナノ材料の有害性の早期予測バイオマーカーの探索
西田 千夏; 和泉 弘人; 友永 泰介; 矢寺 和博; 森本 泰夫
日本呼吸器学会誌, Mar. 2019

Findings as a starting point to unravel the underlying mechanisms of in vivo interactions involving Wnt10a in bone, fat and muscle
Manabu Tsukamoto; Ke-Yong Wang; Takashi Tasaki; Yoichi Murata; Yasuaki Okada; Yoshiaki Yamanaka; Eiichiro Nakamura; Sohsuke Yamada; Hiroto Izumi; Qian Zhou; Kagaku Azuma; Yasuyuki Sasaguri; Kimitoshi Kohno; Akinori Sakai
Bone, Mar. 2019, Reviewed

Complex consisting of antisense DNA and β-glucan promotes internalization into cell through Dectin-1 and hybridizes with target mRNA in cytosol.
Nobuaki Fujiwara; Hiroto Izumi; Yasuo Morimoto; Kazuo Sakurai; Shinichi Mochizuki
Cancer gene therapy, Feb. 2019, Reviewed, No invitation

酸化タングステンの吸入ばく露試験による有害性評価
丸居 誉; 吉浦 由貴子; 和泉 弘人; 友永 泰介; 藤澤 有里; 西田 千夏; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, Jan. 2019

Depletion of WNT10A prevents tumor growth by suppressing microvessels and collagen expression
Motona Kumagai; Xin Guo; Ke-Yong Wang; Hiroto Izumi; Manabu Tsukamoto; Tamiji Nakashima; Takashi Tasaki; Nozomu Kurose; Hidetaka Uramoto; Yasuyuki Sasaguri; Kimitoshi Kohno; Sohsuke Yamada
International Journal of Medical Sciences, 2019

Usefulness of myeloperoxidase as a biomarker for the ranking of pulmonary toxicity of nanomaterials.
Taisuke Tomonaga; Hiroto Izumi; Yukiko Yoshiura; Toshihiko Myojo; Takako Oyabu; Byeong-Woo Lee; Takami Okada; Takashi Marui; Ke-Yong Wang; Masaru Kubo; Manabu Shimada; Shingo Noguchi; Chinatsu Nishida; Kazuhiro Yatera; Yasuo Morimoto
Particle and fibre toxicology, Oct. 2018, Reviewed

気管内注入試験によるトナーの慢性影響に関する検討
丸居 誉; 吉浦 由貴子; 友永 泰介; 和泉 弘人; 西田 千夏; 矢寺 和博; 森本 泰夫
産業衛生学雑誌, May 2018

工業用ナノ材料の有害性評価 免疫染色法の有用性
森本 泰夫; 和泉 弘人; 吉浦 由貴子; 藤澤 有里; 友永 泰介; 丸居 誉; 岡田 崇顧; 大藪 貴子; 明星 敏彦; 西田 千夏; 矢寺 和博
産業衛生学雑誌, May 2018

酸化亜鉛ナノ粒子の肺内滞留性 吸入曝露試験と気管内注入試験
大藪 貴子; 森本 泰夫; 和泉 弘人; 吉浦 由貴子; 岡田 崇顧; 友永 泰介; 明星 敏彦
産業衛生学雑誌, May 2018

ナノ材料の肺有害性を評価するmicroRNAの探索
和泉 弘人; 吉浦 由貴子; 藤澤 有里; 丸居 誉; 友永 泰介; 大藪 貴子; 岡田 崇顧; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, May 2018

Critical in vivo roles of WNT10A in woud healing by regulating collagen expression/ synthesis in WNT10A-deficient mice.
ke-Yong Wang; Sohsuke Yamada; Hiroto Izumi; Manabu Tsukamoto; Tamiji Nakashima; Takashi Tasaki; Xin Guo; Hidetaka Uramoto; Yasuyuki Sasaguri; Kimitoshi Kohno
PLOS one, Mar. 2018, Reviewed, No invitation

Biopersistence of NiO and TiO2 nanoparticles following intratracheal instillation and inhalation
Takako Oyabu; Toshihiko Myojo; Byeong-Woo Lee; Takami Okada; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Yun-Shan Li; Kazuaki Kawai; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Kenji Kawaguchi; Takeshi Sasaki; Yasuo Morimoto
International Journal of Molecular Sciences, Dec. 2017, Reviewed, No invitation

Lovastatin induced Kruppel like factor 2 (KLF2), Kruppel like factor 6 (KLF6) and Ras homolog family member B (RHOB) genes and preferentially led to viability reduction of Cisplatin-resistant cells.
Chiho Koi; Hiroto Izumi; Tomoko Kurita; Thuy Thi Nguyen; Midori Murakami; Yukiko Yoshiura; Toru Hachisuga; Yasuo Morimoto
Oncotarget, Dec. 2017

Expression of N-Acetylgalactosaminyltransferase-6 Is Related to Expression of Cell Adhesion Molecules in Endometrial Cancer.
Tomoko Kurita; Thuy Nguyen Thi; Chiho Koi; Midori Murakami; Seiji Kagami; Hiroto Izumi; Toru Hachisuga
Anticancer research, Jul. 2017

工業用ナノ材料の有害性評価システムの検討
森本 泰夫; 和泉 弘人; 吉浦 由貴子; 藤澤 有里; 友永 泰介; 大藪 貴子; 明星 敏彦
The Journal of Toxicological Sciences, Jun. 2017

気管内投与試験が吸入毒性評価スクリーニング試験として有用性
森本 泰夫; 和泉 弘人; 吉浦 由貴子; 藤澤 有里; 友永 泰介; 大藪 貴子; 岡田 崇顧; 明星 敏彦
産業衛生学雑誌, May 2017

多層カーボンナノチューブ(MWCNT)の細胞内取り込み機序とその意義
藤澤 有里; 和泉 弘人; 吉浦 由貴子; 友永 泰介; 森本 泰夫
産業衛生学雑誌, May 2017

シリカ粒子気管内注入によるBALF中SP-Dの検討
吉浦 由貴子; 和泉 弘人; 藤澤 有里; 友永 泰介; 大藪 貴子; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, May 2017

ナノ材料による肺の有害性を遺伝子発現量で早期に評価する方法の開発
和泉 弘人; 吉浦 由貴子; 藤澤 有里; 友永 泰介; 大藪 貴子; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, May 2017

GalNAc-T6 in the relationship with invasion ability of endometrial carcinomas and prognostic significance.
Thuy Thi Nguyen; Tomoko Kurita; Chiho Koi; Midori Murakami; Seiji Kagami; Toru Hachisuga; Hisaoka Masanori; Yasuo Morimoto; Hiroto Izumi
American journal of cancer research, 2017

Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives
Taisuke Tomonaga; Hiroto Izumi; Yukiko Yoshiura; Toshihiko Myojo; Takako Oyabu; Byeong-Woo Lee; Takami Okada; Yunshan Li; Kazuaki Kawai; Toshiaki Higashi; Yasuo Morimoto
BIOMED RESEARCH INTERNATIONAL, 2017, Reviewed, No invitation

ナノ粒子の有害性指標としての肺内滞留性
大藪 貴子; 吉浦 由紀子; 友永 泰介; 和泉 弘人; 森本 泰夫; 明星 敏彦
産業衛生学雑誌, Jan. 2017

工業用ナノ材料の有害性評価におけるSP-Dの有用性の検討
吉浦 由貴子; 和泉 弘人; 友永 泰介; 藤澤 有里; 大藪 貴子; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, Jan. 2017

Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression
Tomohiro Shibata; Kosuke Watari; Hiroto Izumi; Akihiko Kawahara; Satoshi Hattori; Chihiro Fukumitsu; Yuichi Murakami; Ryuji Takahashi; Uhi Toh; Ken-ichi Ito; Shigehiro Ohdo; Maki Tanaka; Masayoshi Kage; Michihiko Kuwano; Mayumi Ono
CANCER RESEARCH, Jan. 2017, Reviewed, No invitation

In vitro evaluation of a combination treatment involving anticancer agents and an aurora kinase B inhibitor.
Senna Sakai; Hiroto Izumi; Yukiko Yoshiura; Yoshifumi Nakayama; Takahiro Yamaguchi; Yoshikazu Harada; Chiho Koi; Hiroyuki Kurata; Yasuo Morimoto
Oncology letters, Nov. 2016, Reviewed, No invitation

Evaluation of Pulmonary Toxicity of Zinc Oxide Nanoparticles Following Inhalation and Intratracheal Instillation
Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Takako Oyabu; Toshihiko Myojo; Kazuaki Kawai; Kazuhiro Yatera; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Shinichi Kitajima; Etsushi Kuroda; Kenji Kawaguchi; Takeshi Sasaki
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Aug. 2016, Reviewed, No invitation

Optimal sequence of antisense DNA to silence YB-1 in lung cancer by use of a novel polysaccharide drug delivery system
Hiroto Izumi; Shohei Nagao; Shinichi Mochizuki; Nobuaki Fujiwara; Kazuo Sakurai; Yasuo Morimoto
INTERNATIONAL JOURNAL OF ONCOLOGY, Jun. 2016, Reviewed, No invitation

酸化セリウムのラット肺内炎症を指標とする有害性評価の検討 吸入ばく露試験と気管内注入試験の比較
和泉 弘人; 吉浦 由貴子; 藤嶋 けい; 友永 泰介; 大藪 貴子; 明星 敏彦; 岡田 崇顧; 森本 泰夫
産業衛生学雑誌, May 2016

工業用ナノ材料の有害性評価指標としてのBALF中SP-D濃度の有用性
吉浦 由貴子; 和泉 弘人; 藤嶋 けい; 友永 泰介; 岡田 崇顧; 大藪 貴子; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, May 2016

酸化セリウムナノ粒子の肺内滞留性 吸入曝露試験と気管内注入試験
大藪 貴子; 森本 泰夫; 和泉 弘人; 岡田 崇顧; 友永 泰介; 吉浦 由貴子; 明星 敏彦
産業衛生学雑誌, May 2016

トナーの長期吸入ばく露試験における肺炎症性の検討
友永 泰介; 和泉 弘人; 吉浦 由貴子; 大藪 貴子; 明星 敏彦; 岡田 崇顧; 李 秉雨; 森本 泰夫
産業衛生学雑誌, May 2016

Comparison of pulmonary inflammatory responses following intratracheal instillation and inhalation of nanoparticles
Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Byeong-Woo Lee; Takami Okada; Takako Oyabu; Toshihiko Myojo; Kazuaki Kawai; Kazuhiro Yatera; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Shinichi Kitajima; Etsushi Kuroda; Masanori Horie; Kenji Kawaguchi; Takeshi Sasaki
NANOTOXICOLOGY, May 2016, Reviewed, No invitation

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease
Aya Nawata; Hirotsugu Noguchi; Yuichi Mazaki; Toshihiro Kurahashi; Hiroto Izumi; Ke-Yong Wang; Xin Guo; Hidetaka Uramoto; Kimitoshi Kohno; Hatsumi Taniguchi; Yoshiya Tanaka; Junichi Fujii; Yasuyuki Sasaguri; Akihide Tanimoto; Toshiyuki Nakayama; Sohsuke Yamada
PLOS ONE, Apr. 2016, Reviewed, No invitation

Comparison of the Pulmonary Oxidative Stress Caused by Intratracheal Instillation and Inhalation of NiO Nanoparticles when Equivalent Amounts of NiO Are Retained in the Lung.
Masanori Horie; Yukiko Yoshiura; Hiroto Izumi; Takako Oyabu; Taisuke Tomonaga; Takami Okada; Byeong-Woo Lee; Toshihiko Myojo; Masaru Kubo; Manabu Shimada; Yasuo Morimoto
Antioxidants (Basel, Switzerland), Jan. 2016

工業用ナノ材料の有害性評価におけるLDHの有用性
吉浦 由貴子; 和泉 弘人; 友永 泰介; 岡田 崇顧; 李 秉雨; 藤嶋 けい; 大藪 貴子; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, Jan. 2016

Comparison between whole-body inhalation and nose-only inhalation on the deposition and health effects of nanoparticles
Takako Oyabu; Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Byeong-Woo Lee; Takami Okada; Toshihiko Myojo; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Kenji Kawaguchi; Takeshi Sasaki
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE, Jan. 2016, Reviewed, No invitation

Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma
Yoshikazu Harada; Hiroto Izumi; Hirotsugu Noguchi; Akihiro Kuma; Yuichiro Kawatsu; Tomoko Kimura; Shohei Kitada; Hidetaka Uramoto; Ke-Yong Wang; Yasuyuki Sasaguri; Hiroshi Hijioka; Akihiko Miyawaki; Ryoichi Oya; Toshiyuki Nakayama; Kimitoshi Kohno; Sohsuke Yamada
TUMOR BIOLOGY, Jan. 2016, Reviewed, No invitation

Erratum to: Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma
Yoshikazu Harada; Hiroto Izumi; Hirotsugu Noguchi; Akihiro Kuma; Yuichiro Kawatsu; Tomoko Kimura; Shohei Kitada; Hidetaka Uramoto; Ke-Yong Wang; Yasuyuki Sasaguri; Hiroshi Hijioka; Akihiko Miyawaki; Ryoichi Oya; Toshiyuki Nakayama; Kimitoshi Kohno; Sohsuke Yamada
Tumor Biology, Dec. 2015

Pulmonary toxicity of well-dispersed cerium oxide nanoparticles following intratracheal instillation and inhalation
Yasuo Morimoto; Hiroto Izumi; Yukiko Yoshiura; Taisuke Tomonaga; Takako Oyabu; Toshihiko Myojo; Kazuaki Kawai; Kazuhiro Yatera; Manabu Shimada; Masaru Kubo; Kazuhiro Yamamoto; Shinichi Kitajima; Etsushi Kuroda; Kenji Kawaguchi; Takeshi Sasaki
JOURNAL OF NANOPARTICLE RESEARCH, Nov. 2015, Reviewed, No invitation

Mitochondrial Transcription Factor A and Mitochondrial Genome as Molecular Targets for Cisplatin-Based Cancer Chemotherapy.
Kimitoshi Kohno; Ke-Yong Wang; Mayu Takahashi; Tomoko Kurita; Yoichiro Yoshida; Masakazu Hirakawa; Yoshikazu Harada; Akihiro Kuma; Hiroto Izumi; Shinji Matsumoto
International journal of molecular sciences, Aug. 2015, Reviewed, No invitation

Pulmonary toxicity of well-dispersed titanium dioxide nanoparticles following intratracheal instillation
Yukiko Yoshiura; Hiroto Izumi; Takako Oyabu; Masayoshi Hashiba; Tatsunori Kambara; Yohei Mizuguchi; Byeong Woo Lee; Takami Okada; Taisuke Tomonaga; Toshihiko Myojo; Kazuhiro Yamamoto; Shinichi Kitajima; Masanori Horie; Etsushi Kuroda; Yasuo Morimoto
JOURNAL OF NANOPARTICLE RESEARCH, Jun. 2015, Reviewed, No invitation

工業用ナノ材料の有害性評価気管内投与試験が吸入毒性評価のスクリーニング試験として有用性
森本 泰夫; 和泉 弘人; 吉浦 由貴子; 友永 泰介; 大藪 貴子; 岡田 崇顧; 明星 敏彦
産業衛生学雑誌, May 2015

酸化ニッケルの肺有害性を評価する遺伝子の探索
和泉 弘人; 吉浦 由貴子; 友永 泰介; 大藪 貴子; 明星 敏彦; 岡田 崇顧; 森本 泰夫
産業衛生学雑誌, May 2015

ナノ粒子における肺障害評価指標の検討 ラットの気管支肺胞洗浄液中のミエロペルオキシダーゼの測定
友永 泰介; 和泉 弘人; 吉浦 由貴子; 明星 敏彦; 大藪 貴子; 岡田 崇顧; 森本 泰夫
産業衛生学雑誌, May 2015

気管内注入試験による二酸化チタンナノ粒子の有害性評価
吉浦 由貴子; 和泉 弘人; 友永 泰介; 大藪 貴子; 岡田 崇顧; 明星 敏彦; 森本 泰夫
産業衛生学雑誌, May 2015

吸入曝露試験および気管内注入試験におけるナノ粒子の肺内滞留性
大藪 貴子; 森本 泰夫; 和泉 弘人; 岡田 崇顧; 友永 泰介; 吉浦 由貴子; 明星 敏彦
産業衛生学雑誌, May 2015

Expression of BAF57 in ovarian cancer cells and drug sensitivity
Takahiro Yamaguchi; Tomoko Kurita; Kazuto Nishio; Junichi Tsukada; Toru Hachisuga; Yasuo Morimoto; Yoshiko Iwai; Hiroto Izumi
Cancer Science, Apr. 2015, Reviewed, No invitation

CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib in human lung cancer cell lines
Masashi Maeda; Yuichi Murakami; Kosuke Watari; Michihiko Kuwano; Hiroto Izumi; Mayumi Ono
Lung Cancer, Mar. 2015

The combination of strong immunohistochemical mtTFA expression and a high survivin index predicts a shorter disease-specific survival in pancreatic ductal adenocarcinoma
Tomoko Kimura; Shohei Kitada; Hidetaka Uramoto; Li Zhi; Yuichiro Kawatsu; Toru Takeda; Seichi Horie; Atsunori Nabeshima; Hirotsugu Noguchi; Yasuyuki Sasaguri; Hiroto Izumi; Kimitoshi Kohno; Sohsuke Yamada
HISTOLOGY AND HISTOPATHOLOGY, Feb. 2015, Reviewed, No invitation

Y-box binding protein 1 expression in gastric cancer subtypes and association with cancer neovasculature
Y. Wu; K. -Y. Wang; Z. Li; Y. -P. Liu; H. Izumi; S. Yamada; H. Uramoto; Y. Nakayama; K. Ito; K. Kohno
CLINICAL & TRANSLATIONAL ONCOLOGY, Feb. 2015, Reviewed, No invitation

Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction
Ying Wu; Ke-yong Wang; Zhi Li; Yun-peng Liu; Hiroto Izumi; Hidetaka Uramoto; Yoshifumi Nakayama; Ken-ichi Ito; Kimitoshi Kohno
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, Dec. 2014, Reviewed, No invitation

The combination of a nuclear HMGB1-positive and HMGB2-negative expression is potentially associated with a shortened survival in patients with pancreatic ductal adenocarcinoma
Toru Takeda; Hiroto Izumi; Shohei Kitada; Hidetaka Uramoto; Takashi Tasaki; Li Zhi; Xin Guo; Yuichiro Kawatsu; Tomoko Kimura; Seichi Horie; Atsunori Nabeshima; Hirotsugu Noguchi; Ke-Yong Wang; Yasuyuki Sasaguri; Kimitoshi Kohno; Sohsuke Yamada
TUMOR BIOLOGY, Oct. 2014, Reviewed, No invitation

Role of WNT10A-Expressing Kidney Fibroblasts in Acute Interstitial Nephritis
Akihiro Kuma; Sohsuke Yamada; Ke-Yong Wang; Noriaki Kitamura; Takahiro Yamaguchi; Yoshiko Iwai; Hiroto Izumi; Masahito Tamura; Yutaka Otsuji; Kimitoshi Kohno
PLOS ONE, Jul. 2014, Reviewed, No invitation

Tumor-Derived Interleukin-1 Promotes Lymphangiogenesis and Lymph Node Metastasis through M2-Type Macrophages
Kosuke Watari; Tomohiro Shibata; Akihiko Kawahara; Ken-ichi Sata; Hiroshi Nabeshima; Ai Shinoda; Hideyuki Abe; Koichi Azuma; Yuichi Murakami; Hiroto Izumi; Takashi Takahashi; Masayoshi Kage; Michihiko Kuwano; Mayumi Ono
PLOS ONE, Jun. 2014, Reviewed, No invitation

Molecular Mechanisms of Cadmium-Induced Fibroblast Growth Factor 23 Upregulation in Osteoblast-Like Cells
Shinsuke Kido; Marina Fujihara; Kengo Nomura; Shohei Sasaki; Rie Mukai; Ritsuko Ohnishi; Ichiro Kaneko; Hiroko Segawa; Sawako Tatsumi; Hiroto Izumi; Kimitoshi Kohno; Ken-ichi Miyamoto
TOXICOLOGICAL SCIENCES, Jun. 2014, Reviewed, No invitation

ナノ粒子の有害性評価におけるミエロペルオキシダーゼの有用性
友永 泰介; 和泉 弘人; 吉浦 由貴子; 明星 敏彦; 大藪 貴子; 李 秉雨; 岡田 崇顧; 森本 泰夫
日本衛生学雑誌, May 2014

工業用ナノ材料の有害性評価 吸入暴露試験の代替試験として気管内投与試験の有用性
森本 泰夫; 和泉 弘人; 吉浦 由貴子; 友永 泰介; 大藪 貴子; 明星 敏彦; 岡田 崇顧; 李 秉雨; 北島 信一
産業衛生学雑誌, May 2014

酸化ニッケルナノ粒子暴露によるラット肺のミエロペルオキシダーゼの検討
友永 泰介; 和泉 弘人; 堀江 祐範; 吉浦 由貴子; 明星 敏彦; 大藪 貴子; 李 秉雨; 岡田 崇顧; 森本 泰夫
産業衛生学雑誌, May 2014

ナノ粒子の有害性評価のための吸入曝露試験と気管内注入試験の同時試行
大藪 貴子; 森本 泰夫; 吉浦 由貴子; 李 秉雨; 岡田 崇顧; 堀江 祐範; 和泉 弘人; 友永 泰介; 明星 敏彦
産業衛生学雑誌, May 2014

The combination of strong expression of ZNF143 and high MIB-1 labelling index independently predicts shorter disease-specific survival in lung adenocarcinoma
Y. Kawatsu; S. Kitada; H. Uramoto; L. Zhi; T. Takeda; T. Kimura; S. Horie; F. Tanaka; Y. Sasaguri; H. Izumi; K. Kohno; S. Yamada
BRITISH JOURNAL OF CANCER, May 2014, Reviewed, No invitation

Quercetin and Glaucoma
Naoya Miyamoto; Hiroto Izumi; Akihiko Tawara; Kimitoshi Kohno
Handbook of Nutrition, Diet and the Eye, Apr. 2014

Depletion of Apoptosis Signal-Regulating Kinase 1 Prevents Bile Duct Ligation-Induced Necroinflammation and Subsequent Peribiliary Fibrosis
Hirotsugu Noguchi; Sohsuke Yamada; Atsunori Nabeshima; Xin Guo; Akihide Tanimoto; Ke-Yong Wang; Shohei Kitada; Takashi Tasaki; Tatsuo Takama; Shohei Shimajiri; Hasita Horlad; Yoshihiro Komohara; Hiroto Izumi; Kimitoshi Kohno; Hidenori Ichijo; Yasuyuki Sasaguri
AMERICAN JOURNAL OF PATHOLOGY, Mar. 2014, Reviewed, No invitation

Vacuolar H+-ATPase: Functional mechanism and potential as a target for cancer chemotherapy
Hiroto Izumi; Kimitoshi Kohno
Handbook of H+-ATPases, Jan. 2014

Hypersensitivity to Aurora Kinase Inhibitors in Cells Resistant against Platinum-Containing Anticancer Agents
Masaki Akiyama; Hiroto Izumi; Ke-Yong Wang; Takahiro Yamaguchi; Akihiro Kuma; Noriaki Kitamura; Yoshikazu Harada; Ryoichi Oya; Koji Yamaguchi; Yoshiko Iwai; Kimitoshi Kohno
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2014, Reviewed, No invitation

N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells
Yuichi Murakami; Kosuke Watari; Tomohiro Shibata; Manami Uba; Hiroki Ureshino; Akihiko Kawahara; Hideyuki Abe; Hiroto Izumi; Naofumi Mukaida; Michihiko Kuwano; Mayumi Ono
Journal of Biological Chemistry, Aug. 2013

Association of Nuclear YB-1 Localization With Lung Resistance-related Protein and Epidermal Growth Factor Receptor Expression in Lung Cancer
Akira Hyogotani; Ken-ichi Ito; Kazuo Yoshida; Hiroto Izumi; Kimitoshi Kohno; Jun Amano
CLINICAL LUNG CANCER, Sep. 2012, Reviewed, No invitation

N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition
Hiroki Ureshino; Yuichi Murakami; Kosuke Watari; Hiroto Izumi; Akihiko Kawahara; Masayoshi Kage; Tokuzo Arao; Kazuto Nishio; Kazuyoshi Yanagihara; Hisafumi Kinoshita; Michihiko Kuwano; Mayumi Ono
PLoS ONE, Jul. 2012, Reviewed, No invitation

TLX controls angiogenesis through interaction with the von Hippel-Lindau protein
Zhao-Jun Zeng; Erik Johansson; Amiko Hayashi; Pavithra L. Chavali; Nina Akrap; Takeshi Yoshida; Kimitoshi Kohno; Hiroto Izumi; Keiko Funa
Biology Open, Jun. 2012, Reviewed, No invitation

Strong YB-1 expression is associated with liver metastasis progression and predicts shorter disease-free survival in advanced gastric cancer
Ying Wu; Sohsuke Yamada; Hiroto Izumi; Zhi Li; Shohei Shimajiri; Ke-Yong Wang; Yun-Peng Liu; Kimitoshi Kohno; Yasuyuki Sasaguri
JOURNAL OF SURGICAL ONCOLOGY, Jun. 2012, Reviewed, No invitation

Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer
Tokiko Ito; Shinobu Kamijo; Hiroto Izumi; Kimitoshi Kohno; Jun Amano; Ken-ichi Ito
BREAST CANCER RESEARCH AND TREATMENT, May 2012, Reviewed, No invitation

Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer
Yoshifumi Nakayama; Masumi Yamauchi; Noritaka Minagawa; Takayuki Torigoe; Hiroto Izumi; Kimitoshi Kohno; Koji Yamaguchi
ONCOLOGY REPORTS, May 2012, Reviewed, No invitation

Mitochondrial transcription factor A regulates BCL2L1 gene expression and is a prognostic factor in serous ovarian cancer
Tomoko Kurita; Hiroto Izumi; Seiji Kagami; Toshinori Kawagoe; Naoyuki Toki; Yusuke Matsuura; Toru Hachisuga; Kimitoshi Kohno
Cancer Science, Feb. 2012, Reviewed, No invitation

Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer
Yoshifumi Nakayama; Takayuki Torigoe; Yuzuru Inoue; Noritaka Minagawa; Hiroto Izumi; Kimitoshi Kohno; Koji Yamaguchi
EXPERIMENTAL AND THERAPEUTIC MEDICINE, Jan. 2012, Reviewed, No invitation

Forced expression of ZNF143 restrains cancer cell growth
Hiroto Izumi; Yoshihiro Yasuniwa; Masaki Akiyama; Takahiro Yamaguchi; Akihiro Kuma; Noriaki Kitamura; Kimitoshi Kohno
Cancers, Dec. 2011, Reviewed, No invitation

mtTFAは核でBCL21の発現を制御し、漿液性卵巣癌の予後不良因子のひとつである(mtTFA regulates BCL2L1 gene expression and is one of the prognostic factors in serous ovarian cancer)
秋山 正樹; 和泉 弘人; 栗田 智子; 山口 享宏; 安庭 義浩; 蜂須賀 徹; 河野 公俊
日本癌学会総会記事, Sep. 2011

Polypeptide N-acetylgalactosaminyltransferase 6 expression in pancreatic cancer is an independent prognostic factor indicating better overall survival
Z. Li; S. Yamada; S. Inenaga; T. Imamura; Y. Wu; K-Y Wang; S. Shimajiri; R. Nakano; H. Izumi; K. Kohno; Y. Sasaguri
BRITISH JOURNAL OF CANCER, Jun. 2011, Reviewed, No invitation

Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells
Hiroto Izumi; Mayu Takahashi; Hidetaka Uramoto; Yoshifumi Nakayama; Tsunehiro Oyama; Ke-Yong Wang; Yasuyuki Sasaguri; Shigeru Nishizawa; Kimitoshi Kohno
CANCER SCIENCE, May 2011, Reviewed, No invitation

Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin
Gen Hirano; Hiroto Izumi; Yoshihiro Yasuniwa; Shohei Shimajiri; Wang Ke-Yong; Yasuyuki Sasagiri; Hitoshi Kusaba; Kaori Matsumoto; Tetsuya Hasegawa; Masayuki Akimoto; Koichi Akashi; Kimitoshi Kohno
INTERNATIONAL JOURNAL OF ONCOLOGY, Apr. 2011, Reviewed, No invitation

Human mitochondrial transcription factor A functions in both nuclei and mitochondria and regulates cancer cell growth
Bin Han; Hiroto Izumi; Yoshihiro Yasuniwa; Masaki Akiyama; Takahiro Yamaguchi; Naohiro Fujimoto; Tetsuro Matsumoto; Bin Wu; Akihide Tanimoto; Yasuyuki Sasaguri; Kimitoshi Kohno
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2011, Reviewed, No invitation

Transcriptional Regulation of Activating Transcription Factor 4 under Oxidative Stress in Retinal Pigment Epithelial ARPE-19/HPV-16 Cells
Naoya Miyamoto; Hiroto Izumi; Rie Miyamoto; Han Bin; Hiroyuki Kondo; Akihiko Tawara; Yasuyuki Sasaguri; Kimitoshi Kohno
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Mar. 2011, Reviewed, No invitation

Clinical usefulness of mitochondrial transcription factor A expression as a predictive marker in colorectal cancer patients treated with FOLFOX.
Yoshida Y; Hasegawa J; Nezu R; Kim YK; Hirota M; Kawano K; Izumi H; Kohno K
Cancer science, Mar. 2011, Reviewed, No invitation

mtTFAは卵巣漿液性嚢胞腺癌の予後不良分子でBcl-XLの発現を制御する
栗田 智子; 鏡 誠治; 卜部 理恵; 川越 俊典; 土岐 尚之; 松浦 祐介; 蜂須賀 徹; 和泉 弘人; 河野 公俊
日本産科婦人科学会雑誌, Feb. 2011

Quercetin Induces the Expression of Peroxiredoxins 3 and 5 via the Nrf2/NRF1 Transcription Pathway
Naoya Miyamoto; Hiroto Izumi; Rie Miyamoto; Hiroyuki Kondo; Akihiko Tawara; Yasuyuki Sasaguri; Kimitoshi Kohno
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Feb. 2011, Reviewed, No invitation

Enhanced expression of nuclear factor I/B in oxaliplatin-resistant human cancer cell lines
Eiji Kashiwagi; Hiroto Izumi; Yoshihiro Yasuniwa; Ryoko Baba; Yoshiaki Doi; Akihiko Kidani; Tokuzo Arao; Kazuto Nishio; Seiji Naito; Kimitoshi Kohno
CANCER SCIENCE, Feb. 2011, Reviewed, No invitation

Molecular mechanism of cisplatin resistance in head and neck cancers
Tetsuro Wakasugi; Hideaki Suzuki; Jun-Ichi Ohkubo; Gunji Nagatani; Hiroto Izumi; Kimitoshi Kohno
Practica Oto-Rhino-Laryngologica, 2011, Reviewed, No invitation

Circadian Disruption Accelerates Tumor Growth and Angio/Stromagenesis through a Wnt Signaling Pathway
Yoshihiro Yasuniwa; Hiroto Izumi; Ke-Yong Wang; Shohei Shimajiri; Yasuyuki Sasaguri; Kazuaki Kawai; Hiroshi Kasai; Takashi Shimada; Koichi Miyake; Eiji Kashiwagi; Gen Hirano; Akihiko Kidani; Masaki Akiyama; Bin Han; Ying Wu; Ichiro Ieiri; Shun Higuchi; Kimitoshi Kohno
PLOS ONE, Dec. 2010, Reviewed, No invitation

Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell-cycle-associated genes
Hiroto Izumi; Tetsuro Wakasugi; Shohei Shimajiri; Akihide Tanimoto; Yasuyuki Sasaguri; Eiji Kashiwagi; Yoshihiro Yasuniwa; Masaki Akiyama; Bin Han; Ying Wu; Takeshi Uchiumi; Tokuzo Arao; Kazuto Nishio; Ryuta Yamazaki; Kimitoshi Kohno
CANCER SCIENCE, Dec. 2010, Reviewed, No invitation

Overexpression of Peroxiredoxin 4 Protects Against High-Dose Streptozotocin-Induced Diabetes by Suppressing Oxidative Stress and Cytokines in Transgenic Mice
Yan Ding; Sohsuke Yamada; Ke-Yong Wang; Shohei Shimajiri; Xin Guo; Akihide Tanimoto; Yoshitaka Murata; Shuji Kitajima; Teruo Watanabe; Hiroto Izumi; Kimitoshi Kohno; Yasuyuki Sasaguri
ANTIOXIDANTS & REDOX SIGNALING, Nov. 2010, Reviewed, No invitation

Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor-Activating Mutations
Chizuko Yamamoto; Yuji Basaki; Akihiko Kawahara; Kazutaka Nakashima; Masayoshi Kage; Hiroto Izumi; Kimitoshi Kohno; Hidetaka Uramoto; Kosei Yasumoto; Michihiko Kuwano; Mayumi Ono
CANCER RESEARCH, Nov. 2010, Reviewed, No invitation

The close correlation between 8-hydroxy-2 '-deoxyguanosine and epidermal growth factor receptor activating mutation in non-small cell lung cancer
Akihiko Kawahara; Koichi Azuma; Satoshi Hattori; Kazutaka Nakashima; Yuji Basaki; Jun Akiba; Sinzo Takamori; Hisamichi Aizawa; Takashi Yanagawa; Hiroto Izumi; Kimitoshi Kohno; Suminori Kono; Masayoshi Kage; Michihiko Kuwano; Mayumi Ono
HUMAN PATHOLOGY, Jul. 2010, Reviewed, No invitation

Enhanced expression of PCAF endows apoptosis resistance in cisplatin-resistant cells
Gen Hirano; Hiroto Izumi; Akihiko Kidani; Yoshihiro Yasuniwa; Bin Han; Hitoshi Kusaba; Koichi Akashi; Michihiko Kuwano; Kimitoshi Kohno
Molecular Cancer Research, Jun. 2010

Y-box binding protein-1 is a novel molecular target for tumor vessels
Mayu Takahashi; Shohei Shimajiri; Hiroto Izumi; Gen Hirano; Eiji Kashiwagi; Yoshihiro Yasuniwa; Ying Wu; Bin Han; Masaki Akiyama; Shigeru Nishizawa; Yasuyuki Sasaguri; Kimitoshi Kohno
CANCER SCIENCE, Jun. 2010, Reviewed, No invitation

Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells
Yuichi Murakami; Fumihito Hosoi; Hiroto Izumi; Yuichiro Maruyama; Hiroki Ureshino; Kosuke Watari; Kimitoshi Kohno; Michihiko Kuwano; Mayumi Ono
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2010, Reviewed, No invitation

Comprehensive Molecular Analyses of Lung Adenocarcinoma with Regard to the Epidermal Growth Factor Receptor, K-ras, MET, and Hepatocyte Growth Factor Status
Takamitsu Onitsuka; Hidetaka Uramoto; Kenji Ono; Mitsuhiro Takenoyama; Takeshi Hanagiri; Tsunehiro Oyama; Hiroto Izumi; Kimitoshi Kohno; Kosei Yasumoto
JOURNAL OF THORACIC ONCOLOGY, May 2010, Reviewed, No invitation

Expression of mitochondrial transcription factor A in endometrial carcinomas: clinicopathologic correlations and prognostic significance.
Naoyuki Toki; Seiji Kagami; Tomoko Kurita; Toshinori Kawagoe; Yusuke Matsuura; Toru Hachisuga; Atsuji Matsuyama; Hiroshi Hashimoto; Hiroto Izumi; Kimitoshi Kohno
Virchows Archiv : an international journal of pathology, Apr. 2010

Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells
Yuji Basaki; Ken-ichi Taguchi; Hiroto Izumi; Yuichi Murakami; Takuya Kubo; Fumihito Hosoi; Kosuke Watari; Kenji Nakano; Hidetoshi Kawaguchi; Shinji Ohno; Kimitoshi Kohno; Mayumi Ono; Michihiko Kuwano
EUROPEAN JOURNAL OF CANCER, Mar. 2010, Reviewed, No invitation

Thioredoxin2 enhances the damaged DNA binding activity of mtTFA through direct interaction.
Kidani A; Izumi H; Yoshida Y; Kashiwagi E; Ohmori H; Tanaka T; Kuwano M; Kohno K
International journal of oncology, Dec. 2009, Reviewed, No invitation

チオレドキシン2はミトコンドリア転写因子と会合し、DNA結合能を増強する(Thioredoxin2 enhance damaged DNA binding activity of mtTFA through direct interaction)
ハン・ビン; 木谷 昭彦; 和泉 弘人; 吉田 陽一郎; 大森 治樹; 田中 恒夫; 桑野 信彦; 河野 公俊
日本癌学会総会記事, Aug. 2009

N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of kappa B Kinase beta Expression
Fumihito Hosoi; Hiroto Izumi; Akihiko Kawahara; Yuichi Murakami; Hisafumi Kinoshita; Masayoshi Kage; Kazuto Nishio; Kimitoshi Kohno; Michihiko Kuwano; Mayumi Ono
CANCER RESEARCH, Jun. 2009, Reviewed, No invitation

Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth
Masaki Shiota; Hiroto Izumi; Akihide Tanimoto; Mayu Takahashi; Naoya Miyamoto; Eiji Kashiwagi; Akihiko Kidani; Gen Hirano; Daisuke Masubuchi; Yasushi Fukunaka; Yoshihiro Yasuniwa; Seiji Naito; Shigeru Nishizawa; Yasuyuki Sasaguri; Kimitoshi Kohno
CANCER RESEARCH, Apr. 2009, Reviewed, No invitation

Transcriptional network and novel mechanisms for drug resistance
Kimitoshi Kohno; Hiroto Izumi
Nishinihon Journal of Urology, Mar. 2009

GALNT3, a gene associated with hyperphosphatemic familial tumoral calcinosis, is transcriptionally regulated by extracellular phosphate and modulates matrix metalloproteinase activity
Ilana Chefetz; Kimitoshi Kohno; Hiroto Izumi; Jouni Uitto; Gabriele Richard; Eli Sprecher
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, Jan. 2009, Reviewed, No invitation

Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance
Naoya Miyamoto; Hiroto Izumi; Takako Noguchi; Yoshihiro Nakajima; Yoshihiro Ohmiya; Masaki Shiota; Akihiko Kidani; Akihiko Tawara; Kimitoshi Kohno
JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 2008, Reviewed, No invitation

Ets regulates peroxiredoxin1 and 5 expressions through their interaction with the high-mobility group protein B1
Masaki Shiota; Hiroto Izumi; Naoya Miyamoto; Takamitsu Onitsuka; Eiji Kashiwagi; Akihiko Kidani; General Hirano; Mayu Takahashi; Mayumi Ono; Michihiko Kuwano; Seiji Naito; Yasuyuki Sasaguri; Kimitoshi Kohno
Cancer Science, 2008

Oncogenic Ras-induced morphologic change is through MEK/ERK signaling pathway to downregulate Stat3 at a Posttranslational level in NIH3T3 cells
Hsiao-Sheng Liu; Wu-Chou Su; Hsuang-Heng Yeh; Chin-Han Wu; Raghavaraju Giri; Ken Kato; Kimitoshi Kohno; Hiroto Izumi; Cheng-Yang Chou
NEOPLASIA, Jan. 2008, Reviewed, No invitation

Twist promotes tumor cell growth through YB-1 expression
Masaki Shiota; Hiroto Izumi; Takamitsu Onitsuka; Naoya Miyamoto; Eiji Kashiwagi; Akihiko Kidani; Akira Yokomizo; Seiji Naito; Kimitoshi Kohno
CANCER RESEARCH, Jan. 2008, Reviewed, No invitation

DNAトポイソメラーゼ阻害剤による転写因子Sp1のリン酸化と転写制御(DNA topoisomerase inhibitor, Etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation)
鬼塚 貴光; 内海 健; 柏木 英志; 木谷 昭彦; 塩田 真己; 宮本 直哉; 浦本 秀隆; 杉尾 賢二; 安元 公正; 和泉 弘人; 河野 公俊
日本癌学会総会記事, Aug. 2007

p73gamma transactivates the p21 promoter through preferential interaction with the p300/CBP-associated factor in human prostate cancer cells.
Yasutomo Momii; Hiroto Izumi; Masaki Shiota; Takamitsu Onitsuka; Tatsuya Abe; Hidenori Kobayashi; Naoya Miyamoto; Takeshi Uchiumi; Kimitoshi Kohno
Oncology reports, Aug. 2007

ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes
T. Wakasugi; H. Izumi; T. Uchiumi; H. Suzuki; T. Arao; K. Nishio; K. Kohno
ONCOGENE, Aug. 2007, Not reviewed, No invitation

A new mechanism for primary resistance to gefitinib in lung adenocarcinoma: The role of a novel G796A mutation in Exon 20 of EGFR
Hidetaka Uramoto; Takeshi Uchiumi; Hiroto Izumi; Kimitcishi Kohno; Tsunehiro Oyama; Kenji Sugi; Kosei Yasumoto
ANTICANCER RESEARCH, Jul. 2007, Reviewed, No invitation

Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines
T. Igarashi; H. Izumi; T. Uchiumi; K. Nishio; T. Arao; M. Tanabe; H. Uramoto; K. Sugio; K. Yasumoto; Y. Sasaguri; K. Y. Wang; Y. Otsuji; K. Kohno
ONCOGENE, Jul. 2007, Not reviewed, No invitation

DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation
Ichiro Niina; Takeshi Uchiumi; Hiroto Izumi; Takayuki Torigoe; Tetsuro Wakasugi; Tomonori Igarashi; Naoya Miyamoto; Takamitsu Onitsuka; Masaki Shiota; Ryuichi Okayasu; Kazuo Chijiiwa; Kimitoshi Kohno
CANCER SCIENCE, Jun. 2007, Reviewed, No invitation

Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells
Y. Basaki; F. Hosoi; Y. Oda; A. Fotovati; Y. Maruyama; S. Oie; M. Ono; H. Izumi; K. Kohno; K. Sakai; T. Shimoyama; K. Nishio; M. Kuwano
ONCOGENE, Apr. 2007, Not reviewed, No invitation

YB-1 is important for an early stage embryonic development - Neural tube formation and cell proliferation
Takeshi Uchiumi; Abbas Fotovati; Takakazu Sasaguri; Kohtaro Shibahara; Tatsuo Shimada; Takao Fukuda; Takanori Nakamura; Hiroto Izumi; Teruhisa Tsuzuki; Michihiko Kuwano; Kimitoshi Kohno
JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2006, Reviewed, No invitation

Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen
Y Kohno; Y Matsuki; A Tanimoto; H Izumi; T Uchiumi; K Kohno; S Shimajiri; Y Sasaguri
BRITISH JOURNAL OF CANCER, Mar. 2006, Reviewed, No invitation

Expression and cellular localization. of dbpC/Contrin in germ cell tumor cell lines
T Yoshida; H Izumi; T Uchiumi; Y Sasaguri; A TaniMoto; T Matsumoto; S Naito; K Kohno
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, Jan. 2006, Reviewed, No invitation

Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel.
Tomoyuki Fujita; Ken-ichi Ito; Hiroto Izumi; Morihiko Kimura; Muneaki Sano; Hiroshi Nakagomi; Kazuma Maeno; Yoshihisa Hama; Kiyoshi Shingu; Shin-ichi Tsuchiya; Kimitoshi Kohno; Minoru Fujimori
Clinical cancer research : an official journal of the American Association for Cancer Research, Dec. 2005

Transcription factors and drug resistance.
Kimitoshi Kohno; Takeshi Uchiumi; Ichiro Niina; Tetsuro Wakasugi; Tomonori Igarashi; Yasutomo Momii; Takeshi Yoshida; Ken-Ichi Matsuo; Naoya Miyamoto; Hiroto Izumi
European journal of cancer (Oxford, England : 1990), Nov. 2005

DNA topoisomerase II poison TAS-103 transactivates GC-Box-dependent transcription via acetylation of Sp1
T Torigoe; H Izumi; T Wakasugi; Niina, I; T Igarashi; T Yoshida; Shibuya, I; K Chijiiwa; K Matsuo; H Itoh; K Kohno
JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2005, Reviewed, No invitation

Cisplatin resistance and transcription factors.
Torigoe T; Izumi H; Ishiguchi H; Yoshida Y; Tanabe M; Yoshida T; Igarashi T; Niina I; Wakasugi T; Imaizumi T; Momii Y; Kuwano M; Kohno K
Current medicinal chemistry. Anti-cancer agents, Jan. 2005, Reviewed, No invitation

The role of nuclear Y-box binding protein 1 as a global marker in drug resistance
M Kuwano; Y Oda; H Izumi; SJ Yang; T Uchiumi; Y Iwamoto; M Toi; T Fujii; H Yamana; H Kinoshita; T Kamura; M Tsuneyoshi; K Yasumoto; K Kohno
MOLECULAR CANCER THERAPEUTICS, Nov. 2004, Not reviewed, No invitation

Structural and functional characterization of two human V-ATPase subunit gene promoters.
Hiroto Izumi; Tomoko Ise; Tadashi Murakami; Takayuki Torigoe; Hiroshi Ishiguchi; Hidetaka Uramoto; Yoichiro Yoshida; Takeshi Yoshida; Mizuho Tanabe; Kimitoshi Kohno
Biochimica et biophysica acta, Jul. 2003

REGULATION OF ANGIOGENESIS BY GROWTH FACTORS
M KUWANO; S USHIRO; M RYUTO; K SAMOTO; H IZUMI; K ITO; T ABE; T NAKAMURA; M ONO; K KOHNO
GROWTH FACTORS: CELL GROWTH, MORPHOGENESIS, AND TRANSFORMATION, 1994, Reviewed, No invitation

最先端医療の今　多糖核酸複合体のドラッグデリバリーシステムへの応用
和泉 弘人, 隅谷 和樹, 櫻井 和朗
Medical Science Digest, Mar. 2021, Null, Null
Lead

[State and treat on the health effect of nanomaterial].
Morimoto Yasuo, Izumi Hiroto, Yamamoto Kazuhiro
Nihon rinsho. Japanese journal of clinical medicine, Feb. 2014, Reviewed, No invitation

高濃度化学物質暴露に起因する中毒性疾患　アスベストを含む職業的粉じん吸入による肺障害
森本泰夫, 和泉弘人, 島田学
アレルギー・免疫, Jul. 2015, Null, Null

ストレス関連疾患予防センターによる過労死等防止対策
宮﨑洋介, 堀江正知, 和泉弘人
健康開発, Jun. 2017, Null, Null
Last

吸入化学物質による肺・気道障害
西田千夏,　矢寺和博,　友永泰介,　和泉弘人,　森本泰夫
別冊日本臨床　領域別症候群シリーズ, Sep. 2021, Reviewed, Invited

職業性呼吸器疾患の現状と課題
森本泰夫,　西田千夏,　友永泰介,　和泉弘人
呼吸器内科, Aug. 2020, Null, Null
Last

特発性間質性肺炎の増悪に関与するmiRNAの探索および機能解析
小田 桂士, 矢寺 和博, 和泉 弘人
大和証券ヘルス財団研究業績集, Mar. 2019, Reviewed, Null
Last

ラットを用いた架橋型アクリル酸系水溶性高分子化合物の肺障害性の検討
東 泰幸, 西田 千夏, 友永 泰介, 和泉 弘人, 森本 泰夫, 山崎 啓, 矢寺 和博
日本呼吸器学会誌, Apr. 2022, Null, Null

有機高分子化合物の肺炎症・線維化能の検討
西田 千夏, 森本 泰夫, 和泉 弘人, 友永 泰介, 東 泰幸, 矢寺 和博
日本呼吸器学会誌, Apr. 2022, Null, Null

スタチンは腫瘍抑制遺伝子を誘導しシスプラチン耐性細胞を感受性にする
厚井知穂, 和泉弘人, 栗田智子, 鏡誠治, 蜂須賀徹
日本癌治療学会学術集会抄録集, Oct. 2017, Not reviewed, No invitation

PAX6標的遺伝子の検索と孤立性黄斑低形成症例における関与
松下 五佳, 和泉 弘人, 近藤 寛之
日本眼科学会雑誌, Mar. 2022, Null, Null

職業性呼吸器疾患について
森本　泰夫,　西田　千夏,　友永　泰介,　和泉　弘人
日本肺サーファクタント・界面医学会雑誌, Sep. 2020, Null, Null
Last

【呼吸器症候群(第3版)-その他の呼吸器疾患を含めて-(II)】アレルギー性肺疾患　喘息、気道疾患　吸入化学物質による肺・気道障害
西田 千夏, 矢寺 和博, 友永 泰介, 和泉 弘人, 森本 泰夫
日本臨床, Sep. 2021, Reviewed, Invited

ナノマテリアルの健康影響に関する現状と対策
森本泰夫, 和泉弘人, 山本和弘
日本臨床, Feb. 2014, Null, Null

歯科技工士の職場における労働衛生管理
森本泰夫,　和泉弘人,　友永泰介,　西田千夏
日本補綴歯科学会誌, Jul. 2020, Null, Null

開催報告　第30回日中韓産業保健学術会議
友永　泰介,　川合　直紀,　和泉　弘人,　森本　泰夫
産業医学ジャーナル, Oct. 2022, Null, Null

国内外の産業医学に関する文献紹介　有機高分子化合物の肺障害についての最近の知見(解説)
友永泰介, 西田千夏, 和泉弘人, 森本泰夫
産業医学ジャーナル, Jan. 2024, Not reviewed, Invited

国内外の産業医学に関する文献紹介　吸入性化学物質の有害性評価指標についての最近の知見　ナノ材料を中心に
友永 泰介, 西田 千夏, 和泉 弘人, 森本 泰夫
産業医学ジャーナル, Mar. 2020, Null, Null

吸入性化学物質の有害性評価指標についての最近の知見～ナノ材料を中心に～
友永泰介,　西田千夏,　和泉弘人,　森本泰夫
Occupational Health Journal, Mar. 2020, Not reviewed, Invited

化学物質の肺病変の種差について肺腫瘍を中心に
森本泰夫,　西田千夏,　友永泰介,　和泉弘人
Occupational　Health Review, Sep. 2019, Not reviewed, Invited
Last

毛髪コルチゾール測定方法の検討
西 健斗, 和泉 弘人, 堀江 正知
産業医科大学雑誌, Mar. 2022, Null, Null

In vitroで培養可能なラット肺胞マクロファージの形態、機能、遺伝子発現解析
加藤 卓, 辛島 晃至, 朝廣 鈴, 寺井 智果子, 友永 泰介, 和泉 弘人, 森本 泰夫
産業医科大学雑誌, Mar. 2022, Null, Null

ラット型肺胞上皮細胞の単離法の検討
朝廣 鈴, 寺井 智果子, 加藤 卓, 辛島 晃至, 友永 泰介, 和泉 弘人, 森本 泰夫
産業医科大学雑誌, Mar. 2022, Null, Null

不死化肺胞上皮細胞を用いたナノ粒子の肺有害性評価指標の開発
友永 泰介, 和泉 弘人, 西田 千夏, 東 泰幸, 森本 泰夫
産業医科大学雑誌, Mar. 2022, Null, Null

ナノ材料の肺障害性を予測するバイオマーカーの有用性の検討
西田 千夏, 和泉 弘人, 友永 泰介, 竹下 潤一, 王 克よう, 山崎 啓, 矢寺 和博, 森本 泰夫
産業医科大学雑誌, Mar. 2022, Null, Null

The Activities of the Center for Stress-related Disease Control and Prevention (CSDC) at the University of Occupational and Environmental Health, Japan
Yosuke Miyazaki, Hiroto Izumi, Seichi Horie
Japanese Journal of Occupational Mental Health, Apr. 2019, Not reviewed, Invited

酸化タングステンナノ粒子の気管内注入によるラット肺への健康影響
丸居 誉, 友永 泰介, 和泉 弘人, 西田 千夏, 東 泰幸, 矢寺 和博, 森本 泰夫
産業衛生学雑誌, May 2022, Null, Null

気管内注入試験による有機粉じん肺障害の検討
西田 千夏, 和泉 弘人, 東 泰幸, 友永 泰介, 矢寺 和博, 森本 泰夫
産業衛生学雑誌, May 2022, Null, Null

アスベストとシリカの気管内注入試験によるエクソソーム内包マイクロRNAの比較解析
友永 泰介, 和泉 弘人, 丸居 誉, 西田 千夏, 東 泰幸, 矢寺 和博, 森本 泰夫
産業衛生学雑誌, May 2022, Null, Null

ネコカリシウイルス誘導性の細胞変性とウイルス粒子数の解析
和泉 弘人, 友永 泰介, 西田 千夏, 東 泰幸, 森本 泰夫
産業衛生学雑誌, May 2022, Null, Null
Lead

カーボンナノチューブの生体影響
森本　泰夫,　友永　泰介,　和泉　弘人,　西田　千夏
繊維状物質研究, Jan. 2021, Null, Null

臨床に役立つ基礎薬理学の用語解説　（第67回）　Sirtuin遺伝子の神経保護作用と神経疾患治療の可能性
和泉弘人
臨床精神薬理, May 2025, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説（第64回）　ラクチル化：新たな翻訳後修飾と精神疾患
和泉弘人
臨床精神薬理, Feb. 2025, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説　（第62回）バーグマングリア細胞
和泉弘人
臨床精神薬理, Dec. 2024, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説　第60回　GADD45(Growth Arrest and DNA Damage-inducible alpha,beta,gamma)family
和泉弘人
臨床精神薬理, Oct. 2024, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説（第44回） mRNA医薬品
和泉弘人
臨床精神薬理, Jun. 2023, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説（第31回）　MMP-9
和泉弘人
臨床精神薬理, May 2022, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説（第36回）　トランスクリプト―ム
和泉弘人
臨床精神薬理, Oct. 2022, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説（第24回）　Total RNAシーケンス
和泉弘人
臨床精神薬理, Oct. 2021, Not reviewed, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説(第15回)　REST(repressor element 1-silencing transcription factor)
和泉 弘人
臨床精神薬理, Jan. 2021, Null, Null
Lead, Corresponding

臨床に役立つ基礎薬理学の用語解説(第4回)　マイクロRNA(miRNA)
和泉 弘人
臨床精神薬理, Feb. 2020, Null, Null
Lead, Corresponding

マイクロRNA（miRNA)
和泉　弘人
臨床精神薬理, Feb. 2020, Not reviewed, Invited
Lead

臨床に役立つ基礎薬理学の用語解説(第4回)　エクソソーム
和泉 弘人
臨床精神薬理, Feb. 2020, Null, Null
Lead, Corresponding

エクソソーム
和泉　弘人
臨床精神薬理, Feb. 2020, Not reviewed, Invited
Lead

Enhanced Therapeutic Efficacy of Immunostimulatory CpG-ODN by Silencing SOCS-1 with Polysaccharide/miR-155 Complexes.
Sumiya Kazuki, Izumi Hiroto, Sakurai Kazuo
ACS applied bio materials, Feb. 2023, Reviewed, No invitation

GalNAc-T6 in the relationship with invasion ability of endometrial carcinomas and prognostic significance.
Nguyen Thuy Thi, Kurita Tomoko, Koi Chiho, Murakami Midori, Kagami Seiji, Hachisuga Toru, Hisaoka Masanori, Morimoto Yasuo, Izumi Hiroto
American journal of cancer research, May 2017, Reviewed, No invitation
Last

Lipid-Induced Endoplasmic Reticulum Stress Impairs Selective Autophagy at the Step of Autophagosome-Lysosome Fusion in Hepatocytes.
Miyagawa Koichiro, Oe Shinji, Honma Yuichi, Izumi Hiroto, Baba Ryoko, Harada Masaru
The American journal of pathology, Jul. 2016, Reviewed, No invitation

Depletion of apoptosis signal-regulating kinase 1 prevents bile duct ligation-induced necroinflammation and subsequent peribiliary fibrosis.
Noguchi Hirotsugu, Yamada Sohsuke, Nabeshima Atsunori, Guo Xin, Tanimoto Akihide, Wang Ke-Yong, Kitada Shohei, Tasaki Takashi, Takama Tatsuo, Shimajiri Shohei, Horlad Hasita, Komohara Yoshihiro, Izumi Hiroto, Kohno Kimitoshi, Ichijo Hidenori, Sasaguri Yasuyuki
The American journal of pathology, Mar. 2014, Reviewed, No invitation

Protective Role of Myelocytic Nitric Oxide Synthases Against Hypoxic Pulmonary Hypertension in Mice.
Ogoshi Takaaki, Tsutsui Masato, Kido Takashi, Sakanashi Mayuko, Naito Keisuke, Oda Keishi, Ishimoto Hiroshi, Yamada Sohsuke, Wang Ke-Yong, Toyohira Yumiko, Izumi Hiroto, Masuzaki Hiroaki, Shimokawa Hiroaki, Yanagihara Nobuyuki, Yatera Kazuhiro, Mukae Hiroshi
American journal of respiratory and critical care medicine, Feb. 2018, Reviewed, Null

Protective Role of Myelocytic Nitric Oxide Synthases against Hypoxic Pulmonary Hypertension in Mice.
Ogoshi Takaaki, Tsutsui Masato, Kido Takashi, Sakanashi Mayuko, Naito Keisuke, Oda Keishi, Ishimoto Hiroshi, Yamada Sohsuke, Wang Ke-Yong, Toyohira Yumiko, Izumi Hiroto, Masuzaki Hiroaki, Shimokawa Hiroaki, Yanagihara Nobuyuki, Yatera Kazuhiro, Mukae Hiroshi
American journal of respiratory and critical care medicine, Jul. 2018, Reviewed, Null

UBE2L6 is Involved in Cisplatin Resistance by Regulating the Transcription of ABCB6
Murakami Midori, Izumi Hiroto, Kurita Tomoko, Koi Chiho, Morimoto Yasuo, Yoshino Kiyoshi
Anti-Cancer Agents in Medicinal Chemistry, 2022, Reviewed, Null

UBE2L6 is Involved in Cisplatin Resistance by Regulating the Transcription of ABCB6.
Murakami Midori, Izumi Hiroto, Kurita Tomoko, Koi Chiho, Morimoto Yasuo, Yoshino Kiyoshi
Anti-cancer agents in medicinal chemistry, Apr. 2020, Reviewed, Null

Hypersensitivity to aurora kinase inhibitors in cells resistant against platinum- containing anticancer agents.
Akiyama Masaki, Izumi Hiroto, Wang Ke-Yong, Yamaguchi Takahiro, Kuma Akihiro, Kitamura Noriaki, Harada Yoshikazu, Oya Ryoichi, Yamaguchi Koji, Iwai Yoshiko, Kohno Kimitoshi
Anti-cancer agents in medicinal chemistry, Jan. 2014, Reviewed, No invitation

Association of UBE2L6 and ABCB6 Expression With Platinum Resistance in Serous Ovarian Carcinoma.
Shibahara Mami, Kurita Tomoko, Murakami Midori, Harada Hiroshi, Koi Chiho, Izumi Hiroto, Yoshino Kiyoshi
Anticancer research, Aug. 2023, Reviewed, No invitation

Prognostic Significance of Mitochondrial Transcription Factor A Expression in Patients with Right- or Left-sided Colorectal Cancer.
Katsuki Takefumi, Nakayama Yoshifumi, Akiyama Masaki, Sawatsubashi Yusuke, Nagata Jun, Minagawa Noritaka, Torigoe Takayuki, Izumi Hiroto, Kohono Kimitoshi, Hirata Keiji
Anticancer research, Jan. 2018, Reviewed, No invitation

Expression of N-Acetylgalactosaminyltransferase-6 Is Related to Expression of Cell Adhesion Molecules in Endometrial Cancer.
Kurita Tomoko, Thi Thuy Nguyen, Koi Chiho, Murakami Midori, Kagami Seiji, Izumi Hiroto, Hachisuga Toru
Anticancer research, Jul. 2017, Reviewed, No invitation

Overexpression of peroxiredoxin 4 protects against high-dose streptozotocin-induced diabetes by suppressing oxidative stress and cytokines in transgenic mice.
Ding Yan, Yamada Sohsuke, Wang Ke-Yong, Shimajiri Shohei, Guo Xin, Tanimoto Akihide, Murata Yoshitaka, Kitajima Shuji, Watanabe Teruo, Izumi Hiroto, Kohno Kimitoshi, Sasaguri Yasuyuki
Antioxidants & redox signaling, Nov. 2010, Reviewed, Null

Comparison of the Pulmonary Oxidative Stress Caused by Intratracheal Instillation and Inhalation of NiO Nanoparticles when Equivalent Amounts of NiO Are Retained in the Lung.
Horie Masanori, Yoshiura Yukiko, Izumi Hiroto, Oyabu Takako, Tomonaga Taisuke, Okada Takami, Lee Byeong-Woo, Myojo Toshihiko, Kubo Masaru, Shimada Manabu, Morimoto Yasuo
Antioxidants (Basel, Switzerland), Jan. 2016, Reviewed, No invitation

The overexpression of peroxiredoxin-4 affects the progression of idiopathic pulmonary fibrosis.
Hanaka Tetsuya, Kido Takashi, Noguchi Shingo, Yamada Sohsuke, Noguchi Hirotsugu, Guo Xin, Nawata Aya, Wang Ke-Yong, Oda Keishi, Takaki Tsutomu, Izumi Hiroto, Ishimoto Hiroshi, Yatera Kazuhiro, Mukae Hiroshi
BMC pulmonary medicine, Dec. 2019, Reviewed, Null

Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives.
Tomonaga Taisuke, Izumi Hiroto, Yoshiura Yukiko, Myojo Toshihiko, Oyabu Takako, Lee Byeong-Woo, Okada Takami, Li Yunshan, Kawai Kazuaki, Higashi Toshiaki, Morimoto Yasuo
BioMed research international, Jan. 2017, Reviewed, No invitation

Human mitochondrial transcription factor A functions in both nuclei and mitochondria and regulates cancer cell growth.
Han Bin, Izumi Hiroto, Yasuniwa Yoshihiro, Akiyama Masaki, Yamaguchi Takahiro, Fujimoto Naohiro, Matsumoto Tetsuro, Wu Bin, Tanimoto Akihide, Sasaguri Yasuyuki, Kohno Kimitoshi
Biochemical and biophysical research communications, Apr. 2011, Reviewed, Null

Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells.
Murakami Yuichi, Hosoi Fumihito, Izumi Hiroto, Maruyama Yuichiro, Ureshino Hiroki, Watari Kosuke, Kohno Kimitoshi, Kuwano Michihiko, Ono Mayumi
Biochemical and biophysical research communications, May 2010, Reviewed, Null

TLX controls angiogenesis through interaction with the von Hippel-Lindau protein.
Zeng Zhao-Jun, Johansson Erik, Hayashi Amiko, Chavali Pavithra L, Akrap Nina, Yoshida Takeshi, Kohno Kimitoshi, Izumi Hiroto, Funa Keiko
Biology open, Jun. 2012, Reviewed, Null

IL-6-Mediated upregulated miRNAs in extracellular vesicles derived from lund human mesencephalic(LUHMES)cells: effects on astrocytes and microglia.
西健斗,　和泉弘人,　友永泰介,　永野千景,　森本泰夫,　堀江正知
Biomolecules, Apr. 2023, Reviewed, No invitation

Induction of potent cell growth inhibition by schizophyllan/K-ras antisense complex in combination with gemcitabine.
Sasaki Shogo, Izumi Hiroto, Morimoto Yasuo, Sakurai Kazuo, Mochizuki Shinichi
Bioorganic & medicinal chemistry, Sep. 2020, Reviewed, Null

Structural analysis of polysaccharide/antisense DNA complexes during cytoplasmic target mRNA hybridization.
Sumiya Kazuki, Izumi Hiroto, Sakurai Kazuo
Bioorganic & medicinal chemistry letters, Oct. 2023, Reviewed, No invitation

Findings as a starting point to unravel the underlying mechanisms of in vivo interactions involving Wnt10a in bone, fat and muscle.
Tsukamoto Manabu, Wang Ke-Yong, Tasaki Takashi, Murata Yoichi, Okada Yasuaki, Yamanaka Yoshiaki, Nakamura Eiichiro, Yamada Sohsuke, Izumi Hiroto, Zhou Qian, Azuma Kagaku, Sasaguri Yasuyuki, Kohno Kimitoshi, Sakai Akinori
Bone, Oct. 2018, Reviewed, No invitation

Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer.
Ito Tokiko, Kamijo Shinobu, Izumi Hiroto, Kohno Kimitoshi, Amano Jun, Ito Ken-Ichi
Breast cancer research and treatment, May 2012, Reviewed, Null

The combination of strong expression of ZNF143 and high MIB-1 labelling index independently predicts shorter disease-specific survival in lung adenocarcinoma
Y Kawatsu, S Kitada, H Uramoto, L Zhi, T Takeda, T Kimura, S Horie, F Tanaka, Y Sasaguri, H Izumi, K Kohno and S Yamada
British Journal of Cancer, Apr. 2014, Null, Null

Bidirectional Regulation between NDRG1 and GSK3β Controls Tumor Growth and Is Targeted by Differentiation Inducing Factor-1 in Glioblastoma
Hiroshi Ito, Kosuke Watari , Tomohiro Shibata , Tomofumi Miyamoto , Yuichi Murakami , Yukiko Nakahara, Hiroto Izumi , Hiroaki Wakimoto, Michihiko Kuwano , Tatsuya Abe, Mayumi Ono.
Cancer Research, Jan. 2020, Reviewed, Null

Complex consisting of antisense DNA and β-glucan promotes internalization into cell through Dectin-1 and hybridizes with target mRNA in cytosol.
Fujiwara Nobuaki, Izumi Hiroto, Morimoto Yasuo, Sakurai Kazuo, Mochizuki Shinichi
Cancer gene therapy, Feb. 2019, Reviewed, No invitation

Bi-directional regulation between NDRG1 and GSK3β controls tumor growth and is targeted by differentiation inducing factor-1 in glioblastoma.
Ito Hiroshi, Watari Kosuke, Shibata Tomohiro, Miyamoto Tomofumi, Murakami Yuichi, Nakahara Yukiko, Izumi Hiroto, Wakimoto Hiroaki, Kuwano Michihiko, Abe Tatsuya, Ono Mayumi
Cancer research, Nov. 2019, Reviewed, Null

Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression.
Shibata Tomohiro, Watari Kosuke, Izumi Hiroto, Kawahara Akihiko, Hattori Satoshi, Fukumitsu Chihiro, Murakami Yuichi, Takahashi Ryuji, Toh Uhi, Ito Ken-Ichi, Ohdo Shigehiro, Tanaka Maki, Kage Masayoshi, Kuwano Michihiko, Ono Mayumi
Cancer research, Jan. 2017, Reviewed, No invitation

Loss of PTEN expression by blocking nuclear translocation of EGR1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-activating mutations.
Yamamoto Chizuko, Basaki Yuji, Kawahara Akihiko, Nakashima Kazutaka, Kage Masayoshi, Izumi Hiroto, Kohno Kimitoshi, Uramoto Hidetaka, Yasumoto Kosei, Kuwano Michihiko, Ono Mayumi
Cancer research, Nov. 2010, Reviewed, Null

Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth.
Shiota Masaki, Izumi Hiroto, Tanimoto Akihide, Takahashi Mayu, Miyamoto Naoya, Kashiwagi Eiji, Kidani Akihiko, Hirano Gen, Masubuchi Daisuke, Fukunaka Yasushi, Yasuniwa Yoshihiro, Naito Seiji, Nishizawa Shigeru, Sasaguri Yasuyuki, Kohno Kimitoshi
Cancer research, Apr. 2009, Reviewed, Null

YPC-21661 and YPC-22026, novel small molecules, inhibit ZNF143 activity in vitro and in vivo.
Haibara Hirotaka, Yamazaki Ryuta, Nishiyama Yukiko, Ono Masahiro, Kobayashi Tsuneyuki, Hokkyo-Itagaki Atsuko, Nishisaka Fukiko, Nishiyama Hiroyuki, Kurita Akinobu, Matsuzaki Takeshi, Izumi Hiroto, Kohno Kimitoshi
Cancer science, May 2017, Reviewed, No invitation

Expression of BAF57 in ovarian cancer cells and drug sensitivity.
Yamaguchi Takahiro, Kurita Tomoko, Nishio Kazuto, Tsukada Junichi, Hachisuga Toru, Morimoto Yasuo, Iwai Yoshiko, Izumi Hiroto
Cancer science, Apr. 2015, Reviewed, No invitation
Last, Corresponding

Mitochondrial transcription factor A regulates BCL2L1 gene expression and is a prognostic factor in serous ovarian cancer.
Kurita Tomoko, Izumi Hiroto, Kagami Seiji, Kawagoe Toshinori, Toki Naoyuki, Matsuura Yusuke, Hachisuga Toru, Kohno Kimitoshi
Cancer science, Feb. 2012, Reviewed, Null
Corresponding

Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells.
Izumi Hiroto, Takahashi Mayu, Uramoto Hidetaka, Nakayama Yoshifumi, Oyama Tsunehiro, Wang Ke-Yong, Sasaguri Yasuyuki, Nishizawa Shigeru, Kohno Kimitoshi
Cancer science, May 2011, Reviewed, Null
Lead

Clinical usefulness of mitochondrial transcription factor A expression as a predictive marker in colorectal cancer patients treated with FOLFOX.
Yoshida Yoichiro, Hasegawa Junichi, Nezu Riichiro, Kim Yong-Kook, Hirota Masaki, Kawano Kiyoshi, Izumi Hiroto, Kohno Kimitoshi
Cancer science, Mar. 2011, Reviewed, Null

Enhanced expression of nuclear factor I/B in oxaliplatin-resistant human cancer cell lines.
Kashiwagi Eiji, Izumi Hiroto, Yasuniwa Yoshihiro, Baba Ryoko, Doi Yoshiaki, Kidani Akihiko, Arao Tokuzo, Nishio Kazuto, Naito Seiji, Kohno Kimitoshi
Cancer science, Feb. 2011, Reviewed, Null

Y-box binding protein-1 is a novel molecular target for tumor vessels.
Takahashi Mayu, Shimajiri Shohei, Izumi Hiroto, Hirano Gen, Kashiwagi Eiji, Yasuniwa Yoshihiro, Wu Ying, Han Bin, Akiyama Masaki, Nishizawa Shigeru, Sasaguri Yasuyuki, Kohno Kimitoshi
Cancer science, Jun. 2010, Reviewed, Null

Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell-cycle-associated genes.
Izumi Hiroto, Wakasugi Tetsuro, Shimajiri Shohei, Tanimoto Akihide, Sasaguri Yasuyuki, Kashiwagi Eiji, Yasuniwa Yoshihiro, Akiyama Masaki, Han Bin, Wu Ying, Uchiumi Takeshi, Arao Tokuzo, Nishio Kazuto, Yamazaki Ryuta, Kohno Kimitoshi
Cancer science, Dec. 2010, Reviewed, Null
Lead

Forced Expression of ZNF143 Restrains Cancer Cell Growth.
Izumi Hiroto, Yasuniwa Yoshihiro, Akiyama Masaki, Yamaguchi Takahiro, Kuma Akihiro, Kitamura Noriaki, Kohno Kimitoshi
Cancers, Oct. 2011, Reviewed, Null
Lead

Binding assay of human Dectin-1 variants for DNA/ β-glucan complex for active-targeting delivery of antisense DNA: Part II.
Sumiya Kazuki, Izumi Hiroto, Adachi Yoshiyuki, Mochizuki Shinichi, Sakurai Kazuo
Carbohydrate Research, Jan. 2023, Reviewed, No invitation

Binding assay of human Dectin-1 variants to DNA/β-glucan complex for active-targeting delivery of antisense DNA.
Fujiwara Nobuaki, Izumi Hiroto, Kira Ryoma, Morimoto Yasuo, Mochizuki Shinichi, Sakurai Kazuo
Carbohydrate research, Feb. 2021, Reviewed, Null

Telomere Function and the G-Quadruplex Formation are Regulated by hnRNP U.
Izumi Hiroto, Funa Keiko
Cells, Apr. 2019, Reviewed, No invitation
Lead

Association of nuclear YB-1 localization with lung resistance-related protein and epidermal growth factor receptor expression in lung cancer.
Hyogotani Akira, Ito Ken-ichi, Yoshida Kazuo, Izumi Hiroto, Kohno Kimitoshi, Amano Jun
Clinical lung cancer, Sep. 2012, Reviewed, Null

Comparison between whole-body inhalation and nose-only inhalation on the deposition and health effects of nanoparticles.
Oyabu Takako, Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Tomonaga Taisuke, Lee Byeong-Woo, Okada Takami, Myojo Toshihiko, Shimada Manabu, Kubo Masaru, Yamamoto Kazuhiro, Kawaguchi Kenji, Sasaki Takeshi
Environmental health and preventive medicine, Jan. 2016, Reviewed, No invitation

Intracellular HMGB1 transactivates the human IL1B gene promoter through association with an Ets transcription factor PU.1.
Mouri Fumihiko, Tsukada Junichi, Mizobe Takamitsu, Higashi Takehiro, Yoshida Yasuhiro, Minami Yasuhiro, Izumi Hiroto, Kominato Yoshihiko, Kohno Kimitoshi, Tanaka Yoshiya
European journal of haematology, Jan. 2008, Reviewed, No invitation

Intracellular HMGB1 transactivates the human IL1B gene promoter through association with an Ets transcription factor PU.1.
Mouri Fumihiko, Tsukada Junichi, Mizobe Takamitsu, Higashi Takehiro, Yoshida Yasuhiro, Minami Yasuhiro, Izumi Hiroto, Kominato Yoshihiko, Kohno Kimitoshi, Tanaka Yoshiya
European journal of haematology, Jan. 2008, Reviewed, No invitation

Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer.
Nakayama Yoshifumi, Torigoe Takayuki, Inoue Yuzuru, Minagawa Noritaka, Izumi Hiroto, Kohno Kimitoshi, Yamaguchi Koji
Experimental and therapeutic medicine, Jan. 2012, Reviewed, Null

Functional Characteristics of Diverse PAX6 Mutations Associated with Isolated Foveal Hypoplasia.
Matsushita Itsuka, Izumi Hiroto, Ueno Shinji, Hayashi Takaaki, Fujinami Kaoru, Tsunoda Kazushige, Iwata Takeshi, Kiuchi Yoshiaki, Kondo Hiroyuki
Genes, Jul. 2023, Reviewed, No invitation

Prognostic significance of BAF57 expression in patients with endometrial carcinoma
Kagami Seiji, Kurita Tomoko, Kawagoe Toshinori, Toki Naoyuki, Matsuura Yusuke, Hachisuga Toru, Matsuyama Atsuji, Hashimoto Hiroshi, Izumi Hiroto, Kohno Kimitoshi
Histology and Histopathology, May 2012, Reviewed, No invitation

The combination of strong immunohistochemical mtTFA expression and a high survivin index predicts a shorter disease-specific survival in pancreatic ductal adenocarcinoma.
Kimura Tomoko, Kitada Shohei, Uramoto Hidetaka, Zhi Li, Kawatsu Yuichiro, Takeda Toru, Horie Seichi, Nabeshima Atsunori, Noguchi Hirotsugu, Sasaguri Yasuyuki, Izumi Hiroto, Kohno Kimitoshi, Yamada Sohsuke
Histology and histopathology, Feb. 2015, Reviewed, No invitation

Novel WNT10A variant in a Japanese case of nonsyndromic oligodontia.
Adachi Junya, Aoki Yoshihiko, Izumi Hiroto, Nishiyama Takeshi, Nakayama Atsuo, Sana Masatoshi, Morimoto Kyoko, Kaetsu Atsuo, Shirozu Takamasa, Osumi Eriko, Matsuoka Michiko, Hayakawa Eri, Maeda Nasel, Machida Junichiro, Nagao Toru, Tokita Yoshihito
Human genome variation, Jan. 2023, Reviewed, No invitation

WNT10A variants isolated from Japanese patients with congenital tooth agenesis.
Machida Junichiro, Goto Hiroaki, Tatematsu Tadashi, Shibata Akio, Miyachi Hitoshi, Takahashi Katsu, Izumi Hiroto, Nakayama Atsuo, Shimozato Kazuo, Tokita Yoshihito
Human genome variation, 2017, Reviewed, No invitation

The close correlation between 8-hydroxy-2'-deoxyguanosine and epidermal growth factor receptor activating mutation in non-small cell lung cancer.
Kawahara Akihiko, Azuma Koichi, Hattori Satoshi, Nakashima Kazutaka, Basaki Yuji, Akiba Jun, Takamori Sinzo, Aizawa Hisamichi, Yanagawa Takashi, Izumi Hiroto, Kohno Kimitoshi, Kono Suminori, Kage Masayoshi, Kuwano Michihiko, Ono Mayumi
Human pathology, Jul. 2010, Reviewed, Null

Basic study of intratracheal instillation study of nanomaterials for the estimation of the hazards of nanomaterials.
Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Fujisawa Yuri, Yatera Kazuhiro, Fujita Katsuhide, Maru Junko, Endoh Shigehisa, Honda Kazumasa
Industrial health, Feb. 2018, Reviewed, No invitation

Basic study of intratracheal instillation study of nanomaterials for the estimation of the hazards of nanomaterials.
Morimoto Y, Izumi H, Yoshiura Y, Fujisawa Y, Yatera K, Fujita K, Maru J, Endoh S, Honda K.
Industrial health., Feb. 2018, Reviewed, Null

Pulmonary toxicity of printer toner following inhalation and intratracheal instillation.
Morimoto Yasuo, Oyabu Takako, Horie Masanori, Kambara Tatsunori, Izumi Hiroto, Kuroda Etsushi, Creutzenberg Otto, Bellmann Bernd, Pohlmann Gerhard, Schuchardt Sven, Hansen Tanja, Ernst Heinrich
Inhalation toxicology, Oct. 2013, Reviewed, No invitation

Crosslinked Structure of Polyacrylic Acid Affects Pulmonary Fibrogenicity in Rats.
Tomonaga Taisuke, Nishida Chinatsu, Izumi Hiroto, Kawai Naoki, Ke-Yong Wang, Higashi Hidenori,Takeshita Jun-Ichi ,Ono Ryohei , Sumiya Kazuki, Fujii Shota ,Hata Yuki, Sakurai Kazuo , Morimoto Toshiki, Higashi Yasuyuki ,Yamasaki Kei , Yatera Kazuhiro , Morimoto Yasuo
International Journal of Molecular Sciences, Nov. 2022, Reviewed, Invited

Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression.
Kumagai Motona, Guo Xin, Wang Ke-Yong, Izumi Hiroto, Tsukamoto Manabu, Nakashima Tamiji, Tasaki Takashi, Kurose Nozomu, Uramoto Hidetaka, Sasaguri Yasuyuki, Kohno Kimitoshi, Yamada Sohsuke
International journal of medical sciences, Jan. 2019, Null, Null

The Effects of Endoplasmic Reticulum Stress via Intratracheal Instillation of Water-Soluble Acrylic Acid Polymer on the Lungs of Rats.
Morimoto Toshiki, Izumi Hiroto, Tomonaga Taisuke, Nishida Chinatsu, Kawai Naoki, Higashi Yasuyuki, Wang Ke-Yong, Ono Ryohei, Sumiya Kazuki, Sakurai Kazuo, Moriyama Akihiro, Takeshita Jun-Ichi, Yamasaki Kei, Yatera Kazuhiro, Morimoto Yasuo
International journal of molecular sciences, Mar. 2024, Reviewed, Null

Serum Extracellular Vesicle-Derived hsa-miR-2277-3p and hsa-miR-6813-3p Are Potential Biomarkers for Major Depression: A Preliminary Study.
Seki Issei, Izumi Hiroto, Okamoto Naomichi, Ikenouchi Atsuko, Morimoto Yasuo, Horie Seichi, Yoshimura Reiji
International journal of molecular sciences, Sep. 2023, Reviewed, No invitation

Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation.
Nishida Chinatsu, Izumi Hiroto, Tomonaga Taisuke, Wang Ke-Yong, Higashi Hidenori, Takeshita Jun-Ichi, Ono Ryohei, Sumiya Kazuki, Fujii Shota, Hata Yuki, Sakurai Kazuo, Higashi Yasuyuki, Yamasaki Kei, Yatera Kazuhiro, Morimoto Yasuo
International journal of molecular sciences, Sep. 2022, Reviewed, Invited

Examination of Surfactant Protein D as a Biomarker for Evaluating Pulmonary Toxicity of Nanomaterials in Rat.
Tomonaga Taisuke, Izumi Hiroto, Yoshiura Yukiko, Nishida Chinatsu, Yatera Kazuhiro, Morimoto Yasuo
International journal of molecular sciences, Apr. 2021, Reviewed, No invitation

Biopersistence of NiO and TiO₂ Nanoparticles Following Intratracheal Instillation and Inhalation.
Oyabu Takako, Myojo Toshihiko, Lee Byeong-Woo, Okada Takami, Izumi Hiroto, Yoshiura Yukiko, Tomonaga Taisuke, Li Yun-Shan, Kawai Kazuaki, Shimada Manabu, Kubo Masaru, Yamamoto Kazuhiro, Kawaguchi Kenji, Sasaki Takeshi, Morimoto Yasuo
International journal of molecular sciences, Dec. 2017, Reviewed, No invitation

Evaluation of Pulmonary Toxicity of Zinc Oxide Nanoparticles Following Inhalation and Intratracheal Instillation.
Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Tomonaga Taisuke, Oyabu Takako, Myojo Toshihiko, Kawai Kazuaki, Yatera Kazuhiro, Shimada Manabu, Kubo Masaru, Yamamoto Kazuhiro, Kitajima Shinichi, Kuroda Etsushi, Kawaguchi Kenji, Sasaki Takeshi
International journal of molecular sciences, Aug. 2016, Reviewed, No invitation

Usefulness of Intratracheal Instillation Studies for Estimating Nanoparticle-Induced Pulmonary Toxicity.
Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Fujishima Kei, Yatera Kazuhiro, Yamamoto Kazuhiro
International journal of molecular sciences, Jan. 2016, Reviewed, No invitation

Mitochondrial Transcription Factor A and Mitochondrial Genome as Molecular Targets for Cisplatin-Based Cancer Chemotherapy.
Kohno Kimitoshi, Wang Ke-Yong, Takahashi Mayu, Kurita Tomoko, Yoshida Yoichiro, Hirakawa Masakazu, Harada Yoshikazu, Kuma Akihiro, Izumi Hiroto, Matsumoto Shinji
International journal of molecular sciences, Aug. 2015, Reviewed, No invitation

Optimal sequence of antisense DNA to silence YB-1 in lung cancer by use of a novel polysaccharide drug delivery system.
Izumi Hiroto, Nagao Shohei, Mochizuki Shinichi, Fujiwara Nobuaki, Sakurai Kazuo, Morimoto Yasuo
International journal of oncology, Jun. 2016, Reviewed, No invitation
Lead, Corresponding

Circadian disruption and cancer risk: a new concept of stromal niche (review).
Izumi Hiroto, Wang Keyong, Morimoto Yasuo, Sasaguri Yasuyuki, Kohno Kimitoshi
International journal of oncology, Feb. 2014, Reviewed, No invitation
Lead, Corresponding

Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin.
Hirano Gen, Izumi Hiroto, Yasuniwa Yoshihiro, Shimajiri Shohei, Ke-Yong Wang, Sasagiri Yasuyuki, Kusaba Hitoshi, Matsumoto Kaori, Hasegawa Tetsuya, Akimoto Masayuki, Akashi Koichi, Kohno Kimitoshi
International journal of oncology, Apr. 2011, Reviewed, Null

Transcriptional regulation of activating transcription factor 4 under oxidative stress in retinal pigment epithelial ARPE-19/HPV-16 cells.
Miyamoto Naoya, Izumi Hiroto, Miyamoto Rie, Bin Han, Kondo Hiroyuki, Tawara Akihiko, Sasaguri Yasuyuki, Kohno Kimitoshi
Investigative ophthalmology & visual science, Mar. 2011, Reviewed, Null

Quercetin induces the expression of peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway.
Miyamoto Naoya, Izumi Hiroto, Miyamoto Rie, Kondo Hiroyuki, Tawara Akihiko, Sasaguri Yasuyuki, Kohno Kimitoshi
Investigative ophthalmology & visual science, Feb. 2011, Reviewed, Null

Pulmonary toxicity of tungsten trioxide nanoparticles in an inhalation study and an intratracheal instillation study
Marui Takashi , Tomonaga Taisuke , Izumi Hiroto , Yoshiura Yukiko , Nishida Chinatsu , Higashi Hidenori , Ke-Yong Wang , Shijo Miyako , Kubo Masaru , Shimada Manabu , Morimoto Yasuo
Journal of Occupational Health, Jan. 2022, Reviewed, No invitation

Long-term observation of pulmonary toxicity of toner with external additives following a single intratracheal instillation in rats
Tomonaga Taisuke, Izumi Hiroto, Yoshiura Yukiko, Marui Takashi, Ke-Yong Wang, Nishida Chinatsu, Yatera Kazuhiro, Morimoto Yasuo
Journal of Occupational Health, Jun. 2020, Null, Null

Inter-laboratory comparison of pulmonary lesions induced by intratracheal instillation of NiO nanoparticle in rats: Histopathological examination results
Hideki Senoh, Hirokazu Kano, Masaaki Suzuki, Shoji Fukushima, Yutaka Oshima, Toshio Kobayashi, Yasuo Morimoto, Hiroto Izumi, Yasufumi Ota, Hiroshi Takehara, Takamasa Numano, Mayumi Kawabe, Masashi Gamo, Jun-ichi Takeshita
Journal of Occupational Health, Feb. 2020, Reviewed, Null

Significance of Intratracheal Instillation Tests for the Screening of Pulmonary Toxicity of Nanomaterials.
Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Fujisawa Yuri, Fujita Katsuhide
Journal of UOEH, Apr. 2017, Reviewed, Null

N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells.
Murakami Yuichi, Watari Kosuke, Shibata Tomohiro, Uba Manami, Ureshino Hiroki, Kawahara Akihiko, Abe Hideyuki, Izumi Hiroto, Mukaida Naofumi, Kuwano Michihiko, Ono Mayumi
The Journal of biological chemistry, Aug. 2013, Reviewed, Null

Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.
Wu Ying, Wang Ke-yong, Li Zhi, Liu Yun-peng, Izumi Hiroto, Uramoto Hidetaka, Nakayama Yoshifumi, Ito Ken-ichi, Kohno Kimitoshi
Journal of experimental & clinical cancer research : CR, Dec. 2014, Reviewed, No invitation

Significance of persistent inflammation in respiratory disorders induced by nanoparticles.
Morimoto Yasuo, Izumi Hiroto, Kuroda Etsushi
Journal of immunology research, 2014, Reviewed, No invitation

Pulmonary toxicity of well-dispersed titanium dioxide nanoparticles following intratracheal instillation.
Yoshiura Yukiko, Izumi Hiroto, Oyabu Takako, Hashiba Masayoshi, Kambara Tatsunori, Mizuguchi Yohei, Lee Byeong Woo, Okada Takami, Tomonaga Taisuke, Myojo Toshihiko, Yamamoto Kazuhiro, Kitajima Shinichi, Horie Masanori, Kuroda Etsushi, Morimoto Yasuo
Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, Jun. 2015, Reviewed, No invitation

Pulmonary toxicity of well-dispersed cerium oxide nanoparticles following intratracheal instillation and inhalation.
Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Tomonaga Taisuke, Oyabu Takako, Myojo Toshihiko, Kawai Kazuaki, Yatera Kazuhiro, Shimada Manabu, Kubo Masaru, Yamamoto Kazuhiro, Kitajima Shinichi, Kuroda Etsushi, Kawaguchi Kenji, Sasaki Takeshi
Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, Nov. 2015, Reviewed, No invitation

Pulmonary disorder induced by cross-linked polyacrylic acid.
Higashi Yasuyuki, Morimoto Yasuo, Nishida Chinatsu, Tomonaga Taisuke, Izumi Hiroto, Wang Ke-Yong, Higashi Hidenori, Ono Ryohei, Sumiya Kazuki, Sakurai Kazuo, Yamasaki Kei, Yatera Kazuhiro
Journal of occupational health, Jan. 2022, Reviewed, No invitation

Pulmonary toxicity of tungsten trioxide nanoparticles in an inhalation study and an intratracheal instillation study.
Marui Takashi, Tomonaga Taisuke, Izumi Hiroto, Yoshiura Yukiko, Nishida Chinatsu, Higashi Hidenori, Wang Ke-Yong, Shijo Miyako, Kubo Masaru, Shimada Manabu, Morimoto Yasuo
Journal of occupational health, Jan. 2022, Null, Null

Lung disorders induced by respirable organic chemicals.
Morimoto Yasuo, Nishida Chinatsu, Tomonaga Taisuke, Izumi Hiroto, Yatera Kazuhiro, Sakurai Kazuo, Kim Yangho
Journal of occupational health, Jan. 2021, Reviewed, Null

Review of toxicity studies of carbon nanotubes.
Kobayashi Norihiro, Izumi Hiroto, Morimoto Yasuo
Journal of occupational health, Sep. 2017, Reviewed, Null

Strong YB-1 expression is associated with liver metastasis progression and predicts shorter disease-free survival in advanced gastric cancer.
Wu Ying, Yamada Sohsuke, Izumi Hiroto, Li Zhi, Shimajiri Shohei, Wang Ke-Yong, Liu Yun-Peng, Kohno Kimitoshi, Sasaguri Yasuyuki
Journal of surgical oncology, Jun. 2012, Reviewed, Null

NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer.
Azuma Koichi, Kawahara Akihiko, Hattori Satoshi, Taira Tomoki, Tsurutani Junji, Watari Kosuke, Shibata Tomohiro, Murakami Yuichi, Takamori Shinzo, Ono Mayumi, Izumi Hiroto, Kage Masayoshi, Yanagawa Takashi, Nakagawa Kazuhiko, Hoshino Tomoaki, Kuwano Michihiko
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, May 2012, Reviewed, Null

Comprehensive molecular analyses of lung adenocarcinoma with regard to the epidermal growth factor receptor, K-ras, MET, and hepatocyte growth factor status.
Onitsuka Takamitsu, Uramoto Hidetaka, Ono Kenji, Takenoyama Mitsuhiro, Hanagiri Takeshi, Oyama Tsunehiro, Izumi Hiroto, Kohno Kimitoshi, Yasumoto Kosei
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, May 2010, Reviewed, Null

Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
Hiroto Izumi, Yasuo Morimoto
KONA Powder Particle Journal, Sep. 2013, Null, Null
Lead, Corresponding

CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib human lung cancer cell lines.
Maeda M, Murakami Y, Watari K, Kumano M, Izumi H, Ono M
Lung Cancer, Jan. 2015, Null, Null

CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib in human lung cancer cell lines.
Maeda Masashi, Murakami Yuichi, Watari Kosuke, Kuwano Michihiko, Izumi Hiroto, Ono Mayumi
Lung cancer (Amsterdam, Netherlands), Mar. 2015, Reviewed, No invitation

Expression of Mina53, a novel c-Myc target gene, is a favorable prognostic marker in early stage lung cancer.
Komiya Kazutoshi, Sueoka-Aragane Naoko, Sato Akemi, Hisatomi Takashi, Sakuragi Toru, Mitsuoka Masahiro, Sato Toshimi, Hayashi Shinichiro, Izumi Hiroto, Tsuneoka Makoto, Sueoka Eisaburo
Lung cancer (Amsterdam, Netherlands), Aug. 2010, Reviewed, Null

Pleural Plaques as a Predictive_x000D_ Imaging Marker for Cancer Screening_x000D_ in Asbestos-Exposed_x000D_ Subjects: Can Pleural_x000D_ Plaques Be a Tool beyond Estimating Past_x000D_ Asbestos Inhalation?
Morimoto Yasuo, Nishida Chinatsu, TomonagaTaisuke , Izumi Hiroto
Malignant Pleural Mesothelioma, Feb. 2021, Reviewed, Null
Last

Targeting Phosphorylation of Y-Box-Binding Protein YBX1 by TAS0612 and Everolimus in Overcoming Antiestrogen Resistance
Tomohiro Shibata, Kosuke Watari , Akihiko Kawahara , Tomoya Sudo , Satoshi Hattori , Yuichi Murakami , Hiroto Izumi , Junji Itou , Masakazu Toi, Jun Akiba , Yoshito Akagi , Maki Tanaka, Michihiko Kuwano, Mayumi Ono
Molecular cancer Therapeutics, Mar. 2020, Reviewed, Null

Enhanced expression of PCAF endows apoptosis resistance in cisplatin-resistant cells.
Hirano Gen, Izumi Hiroto, Kidani Akihiko, Yasuniwa Yoshihiro, Han Bin, Kusaba Hitoshi, Akashi Koichi, Kuwano Michihiko, Kohno Kimitoshi
Molecular cancer research : MCR, Jun. 2010, Reviewed, Null

Assessment of Cytokine-Induced Neutrophil Chemoattractants as Biomarkers for Prediction of Pulmonary Toxicity of Nanomaterials.
Tomonaga Taisuke, Izumi Hiroto, Oyabu Takako, Lee Byeong-Woo, Kubo Masaru, Shimada Manabu, Noguchi Shingo, Nishida Chinatsu, Yatera Kazuhiro, Morimoto Yasuo
Nanomaterials, Aug. 2020, Reviewed, Null

Predictive Biomarkers for the Ranking of Pulmonary Toxicity of Nanomaterials.
Nishida Chinatsu, Izumi Hiroto, Tomonaga Taisuke, Takeshita Jun-Ichi, Wang Ke-Yong, Yamasaki Kei, Yatera Kazuhiro, Morimoto Yasuo
Nanomaterials, Oct. 2020, Reviewed, No invitation

Comparison of pulmonary inflammatory responses following intratracheal instillation and inhalation of nanoparticles.
Morimoto Yasuo, Izumi Hiroto, Yoshiura Yukiko, Tomonaga Taisuke, Lee Byeong-Woo, Okada Takami, Oyabu Takako, Myojo Toshihiko, Kawai Kazuaki, Yatera Kazuhiro, Shimada Manabu, Kubo Masaru, Yamamoto Kazuhiro, Kitajima Shinichi, Kuroda Etsushi, Horie Masanori, Kawaguchi Kenji, Sasaki Takeshi
Nanotoxicology, 2016, Reviewed, No invitation

In vitro evaluation of a combination treatment involving anticancer agents and an aurora kinase B inhibitor.
Sakai Senna, Izumi Hiroto, Yoshiura Yukiko, Nakayama Yoshifumi, Yamaguchi Takahiro, Harada Yoshikazu, Koi Chiho, Kurata Hiroyuki, Morimoto Yasuo
Oncology letters, Nov. 2016, Reviewed, No invitation
Corresponding

Selection of microRNAs in extracellular vesicles for diagnosis of malignant pleural mesothelioma by in vitro analysis.
Jotatsu Takanobu, Izumi Hiroto, Morimoto Yasuo, Yatera Kazuhiro
Oncology reports, Nov. 2020, Reviewed, No invitation
Corresponding

Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer.
Nakayama Yoshifumi, Yamauchi Masumi, Minagawa Noritaka, Torigoe Takayuki, Izumi Hiroto, Kohno Kimitoshi, Yamaguchi Koji
Oncology reports, May 2012, Reviewed, Null

Lovastatin induced Kruppel like factor 2 (KLF2), Kruppel like factor 6 (KLF6) and Ras homolog family member B (RHOB) genes and preferentially led to viability reduction of Cisplatin-resistant cells.
Koi Chiho, Izumi Hiroto, Kurita Tomoko, Nguyen Thuy Thi, Murakami Midori, Yoshiura Yukiko, Hachisuga Toru, Morimoto Yasuo
Oncotarget, Dec. 2017, Reviewed, No invitation
Corresponding

PATZ1 knockdown enhances malignant phenotype in thyroid epithelial follicular cells and thyroid cancer cells.
Iesato Asumi, Nakamura Teruo, Izumi Hiroto, Uehara Takeshi, Ito Ken-Ichi
Oncotarget, Oct. 2017, Reviewed, Null

ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines.
Oba Takaaki, Izumi Hiroto, Ito Ken-Ichi
Oncotarget, Oct. 2016, Reviewed, No invitation

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor.
Azuma Koichi, Kawahara Akihiko, Sonoda Kahori, Nakashima Kazutaka, Tashiro Kousuke, Watari Kosuke, Izumi Hiroto, Kage Masayoshi, Kuwano Michihiko, Ono Mayumi, Hoshino Tomoaki
Oncotarget, Aug. 2014, Reviewed, No invitation

Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation
Nishida Chinatsu, Tomonaga Taisuke, Izumi Hiroto, Ke‑Yong Wang, Higashi Hidenori, Ishidao Toru,_x000D_ Takeshita Jun‑ichi, Ono Ryohei, Sumiya Kazuki, Fujii Shota, Mochizuki Shinichi, Sakurai Kazuo,_x000D_ Yamasaki Kei, Yatera Kazuhiro, Morimoto Yasuo
Particle and Fibre Toxicology, Jan. 2022, Reviewed, No invitation

Investigation of pulmonary inflammatory responses following intratracheal instillation of and inhalation exposure to polypropylene microplastics.
Tomonaga Taisuke, Higashi Hidenori, Izumi Hiroto, Nishida Chinatsu, Kawai Naoki, Sato Kazuma, Morimoto Toshiki, Higashi Yasuyuki, Yatera Kazuhiro, Morimoto Yasuo
Particle and fibre toxicology, Aug. 2024, Reviewed, No invitation

Usefulness of myeloperoxidase as a biomarker for the ranking of pulmonary toxicity of nanomaterials.
Tomonaga Taisuke, Izumi Hiroto, Yoshiura Yukiko, Myojo Toshihiko, Oyabu Takako, Lee Byeong-Woo, Okada Takami, Marui Takashi, Wang Ke-Yong, Kubo Masaru, Shimada Manabu, Noguchi Shingo, Nishida Chinatsu, Yatera Kazuhiro, Morimoto Yasuo
Particle and fibre toxicology, Oct. 2018, Reviewed, Null

Role of WNT10A-expressing kidney fibroblasts in acute interstitial nephritis.
Kuma Akihiro, Yamada Sohsuke, Wang Ke-Yong, Kitamura Noriaki, Yamaguchi Takahiro, Iwai Yoshiko, Izumi Hiroto, Tamura Masahito, Otsuji Yutaka, Kohno Kimitoshi
PloS one, Jan. 2014, Reviewed, No invitation

Tumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages.
Watari Kosuke, Shibata Tomohiro, Kawahara Akihiko, Sata Ken-ichi, Nabeshima Hiroshi, Shinoda Ai, Abe Hideyuki, Azuma Koichi, Murakami Yuichi, Izumi Hiroto, Takahashi Takashi, Kage Masayoshi, Kuwano Michihiko, Ono Mayumi
PloS one, 2014, Reviewed, No invitation

N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition.
Ureshino Hiroki, Murakami Yuichi, Watari Kosuke, Izumi Hiroto, Kawahara Akihiko, Kage Masayoshi, Arao Tokuzo, Nishio Kazuto, Yanagihara Kazuyoshi, Kinoshita Hisafumi, Kuwano Michihiko, Ono Mayumi
PloS one, 2012, Reviewed, Null

Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway.
Yasuniwa Yoshihiro, Izumi Hiroto, Wang Ke-Yong, Shimajiri Shohei, Sasaguri Yasuyuki, Kawai Kazuaki, Kasai Hiroshi, Shimada Takashi, Miyake Koichi, Kashiwagi Eiji, Hirano Gen, Kidani Akihiko, Akiyama Masaki, Han Bin, Wu Ying, Ieiri Ichiro, Higuchi Shun, Kohno Kimitoshi
PloS one, Dec. 2010, Reviewed, Null

Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.
Wang Ke-Yong, Yamada Sohsuke, Izumi Hiroto, Tsukamoto Manabu, Nakashima Tamiji, Tasaki Takashi, Guo Xin, Uramoto Hidetaka, Sasaguri Yasuyuki, Kohno Kimitoshi
PloS one, Mar. 2018, Reviewed, No invitation

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.
Nawata Aya, Noguchi Hirotsugu, Mazaki Yuichi, Kurahashi Toshihiro, Izumi Hiroto, Wang Ke-Yong, Guo Xin, Uramoto Hidetaka, Kohno Kimitoshi, Taniguchi Hatsumi, Tanaka Yoshiya, Fujii Junichi, Sasaguri Yasuyuki, Tanimoto Akihide, Nakayama Toshiyuki, Yamada Sohsuke
PloS one, Apr. 2016, Reviewed, No invitation

Antisense DNA cocktail therapy using short ß-1,3-glucan/oligonucleotide complexes
Hata Yuki, Sumiya Kazuki, Izumi Hiroto, Sakurai Kazuo
Polymer Journal, Mar. 2023, Reviewed, No invitation

Delivery of therapeutic oligonucleotides targeting Dectin-1 using quantized complexes
Sumiya Kazuki , Izumi Hiroto , Matsunaga Takuya , Tanaka Motoko , Sakurai Kazuo
PolymerJournal, Apr. 2022, Reviewed, No invitation

Profibrotic role of WNT10A via TGF-β signaling in idiopathic pulmonary fibrosis.
Oda Keishi, Yatera Kazuhiro, Izumi Hiroto, Ishimoto Hiroshi, Yamada Sohsuke, Nakao Hiroyuki, Hanaka Tetsuya, Ogoshi Takaaki, Noguchi Shingo, Mukae Hiroshi
Respiratory research, Apr. 2016, Reviewed, No invitation

The degree of cross-linking of polyacrylic acid affects the fibrogenicity in rat lungs
Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kazuma Sato, Yuiko Nakamura,_x000D_ Toshiki Morimoto, Yasuyuki Higashi, Ke-Yong Wang, Hidenori Higashi, Takuma Kojima, Kazuo Sakurai,_x000D_ Jun-ichi Takeshita, Akihiro Moriyama, Kei Yamasaki, Kazuhiro Yatera, Yasuo Morimoto
Scientific Reports, Jan. 2025, Reviewed, No invitation

YBX2 and cancer testis antigen 45 contribute to stemness, chemoresistance and a high degree of malignancy in human endometrial cancer.
Suzuki Izumi, Yoshida Sachiko, Tabu Kouichi, Kusunoki Soshi, Matsumura Yumiko, Izumi Hiroto, Asanoma Kazuo, Yagi Hiroshi, Onoyama Ichiro, Sonoda Kenzo, Kohno Kimitoshi, Taga Tetsuya, Itakura Atsuo, Takeda Satoru, Kato Kiyoko
Scientific reports, Feb. 2021, Reviewed, Null

Monocarboxylate Transporter-1 Mediates the Protective Effects of Neutral-pH Bicarbonate/Lactate-Buffered Peritoneal Dialysis Fluid on Cell Viability and Apoptosis.
Kuma Akihiro, Tamura Masahito, Ishimatsu Nana, Harada Yoshikazu, Izumi Hiroto, Miyamoto Tetsu, Furuno Yumi, Nakano Yoko, Serino Ryota, Otsuji Yutaka
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, Feb. 2017, Reviewed, Null

Expression of polypeptide N-acetylgalactosaminyl transferase-3 and its association with clinicopathological factors in thyroid carcinomas.
Mochizuki Yasuhiro, Ito Ken-ichi, Izumi Hiroto, Kohno Kimitoshi, Amano Jun
Thyroid : official journal of the American Thyroid Association, Dec. 2013, Reviewed, Null

Increased Expression of Y-Box-Binding Protein-1 in Hind-Limb Muscles During Regeneration from Ischemic Injury in Mice.
Fuke Megumi, Narita Makoto, Wada Yuko, Seto Tatsuichiro, Okada Kenji, Nakayama Jun, Izumi Hiroto, Ito Ken-Ichi
The Tohoku journal of experimental medicine, Jan. 2018, Reviewed, No invitation

Molecular mechanisms of cadmium-induced FGF23 upregulation in osteoblast-like cells
Shinsuke Kido, Marina Fujihara, Kengo Nomura, Shohei Sasaki, Rie Mukai, Ritsuko Ohnishi, Ichiro Kaneko, Hiroko Segawa, Sawako Tatsumi, Hiroto Izumi, Kimitoshi Kohno, and Ken-ichi Miyamoto
Toxicological sciences, Mar. 2014, Null, Null

Molecular mechanisms of cadmium-induced fibroblast growth factor 23 upregulation in osteoblast-like cells.
Kido Shinsuke, Fujihara Marina, Nomura Kengo, Sasaki Shohei, Mukai Rie, Ohnishi Ritsuko, Kaneko Ichiro, Segawa Hiroko, Tatsumi Sawako, Izumi Hiroto, Kohno Kimitoshi, Miyamoto Ken-ichi
Toxicological sciences : an official journal of the Society of Toxicology, Jun. 2014, Reviewed, Null

Inhalation exposure to cross-linked polyacrylic acid induces pulmonary disorders.
Higashi Yasuyuki, Nishida Chinatsu, Izumi Hiroto, Sato Kazuma, Kawai Naoki, Tomonaga Taisuke, Morimoto Toshiki, Yamasaki Kei, Wang Ke-Yong, Higashi Hidenori, Moriyama Akihiro, Takeshita Jun-Ichi, Kojima Takuma, Sakurai Kazuo, Yatera Kazuhiro, Morimoto Yasuo
Toxicology, Jan. 2025, Reviewed, No invitation

Intratracheal instillation of polyacrylic acid induced pulmonary fibrosis with elevated transforming growth factor-β1 and connective tissue growth factor.
Higashi Yasuyuki, Nishida Chinatsu, Tomonaga Taisuke, Izumi Hiroto, Kawai Naoki, Morimoto Toshiki, Hara Kanako, Yamasaki Kei, Moriyama Akihiro, Takeshita Jun-Ichi, Wang Ke-Yong, Higashi Hidenori, Ono Ryohei, Sumiya Kazuki, Sakurai Kazuo, Yatera Kazuhiro, Morimoto Yasuo
Toxicology, Aug. 2024, Reviewed, No invitation

Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model.
Tomonaga Taisuke, Izumi Hiroto, Nishida Chinatsu, Kato Kaori, Yatera Kazuhiro, Kuroda Etsushi, Morimoto Yasuo
Toxics, Jan. 2022, Reviewed, No invitation

Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.
Harada Yoshikazu, Izumi Hiroto, Noguchi Hirotsugu, Kuma Akihiro, Kawatsu Yuichiro, Kimura Tomoko, Kitada Shohei, Uramoto Hidetaka, Wang Ke-Yong, Sasaguri Yasuyuki, Hijioka Hiroshi, Miyawaki Akihiko, Oya Ryoichi, Nakayama Toshiyuki, Kohno Kimitoshi, Yamada Sohsuke
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, Jan. 2016, Reviewed, No invitation

The combination of a nuclear HMGB1-positive and HMGB2-negative expression is potentially associated with a shortened survival in patients with pancreatic ductal adenocarcinoma.
Takeda Toru, Izumi Hiroto, Kitada Shohei, Uramoto Hidetaka, Tasaki Takashi, Zhi Li, Guo Xin, Kawatsu Yuichiro, Kimura Tomoko, Horie Seichi, Nabeshima Atsunori, Noguchi Hirotsugu, Wang Ke-Yong, Sasaguri Yasuyuki, Kohno Kimitoshi, Yamada Sohsuke
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, Oct. 2014, Reviewed, No invitation

Peroxiredoxins, thioredoxin, and Y-box-binding protein-1 are involved in the pathogenesis and progression of dialysis-associated renal cell carcinoma.
Fushimi Fumiyoshi, Taguchi Kenichi, Izumi Hiroto, Kohno Kimitoshi, Kuwano Michihiko, Ono Mayumi, Nakashima Yutaka, Takesue Tetsuro, Naito Seiji, Oda Yoshinao
Virchows Archiv : an international journal of pathology, Oct. 2013, Reviewed, Null

Expression of mitochondrial transcription factor A in endometrial carcinomas: clinicopathologic correlations and prognostic significance.
Toki Naoyuki, Kagami Seiji, Kurita Tomoko, Kawagoe Toshinori, Matsuura Yusuke, Hachisuga Toru, Matsuyama Atsuji, Hashimoto Hiroshi, Izumi Hiroto, Kohno Kimitoshi
Virchows Archiv : an international journal of pathology, Apr. 2010, Reviewed, Null

Vacuolar H(+)-ATPase: functional mechanisms and potential as a target for cancer chemotherapy.
Torigoe Takayuki, Izumi Hiroto, Ise Tomoko, Murakami Tadashi, Uramoto Hidetaka, Ishiguchi Hiroshi, Yoshida Yoichiro, Tanabe Mizuho, Nomoto Minoru, Kohno Kimitoshi
Anti-cancer drugs, Mar. 2002, Null, Null

A new mechanism for primary resistance to gefitinib in lung adenocarcinoma: the role of a novel G796A mutation in exon 20 of EGFR.
Uramoto Hidetaka, Uchiumi Takeshi, Izumi Hiroto, Kohno Kimitoshi, Oyama Tsunehiro, Sugio Kenji, Yasumoto Kosei
Anticancer research, Null, Null

The pleiotropic functions of the Y-box-binding protein, YB-1.
Kohno Kimitoshi, Izumi Hiroto, Uchiumi Takeshi, Ashizuka Megumi, Kuwano Michihiko
BioEssays : news and reviews in molecular, cellular and developmental biology, Jul. 2003, Null, Null

Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA.
Yoshida Yoichiro, Izumi Hiroto, Ise Tomoko, Uramoto Hidetaka, Torigoe Takayuki, Ishiguchi Hiroshi, Murakami Tadashi, Tanabe Mizuho, Nakayama Yoshifumi, Itoh Hideaki, Kasai Hiroshi, Kohno Kimitoshi
Biochemical and biophysical research communications, Jul. 2002, Null, Null

p300/CBP-associated factor (P/CAF) interacts with nuclear respiratory factor-1 to regulate the UDP-N-acetyl-alpha-d-galactosamine: polypeptide N-acetylgalactosaminyltransferase-3 gene.
Izumi Hiroto, Ohta Ryo, Nagatani Gunji, Ise Tomoko, Nakayama Yoshifumi, Nomoto Minoru, Kohno Kimitoshi
The Biochemical journal, Aug. 2003, Null, Null

Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression.
Uramoto Hidetaka, Izumi Hiroto, Nagatani Gunji, Ohmori Haruki, Nagasue Naofumi, Ise Tomoko, Yoshida Takeshi, Yasumoto Kosei, Kohno Kimitoshi
The Biochemical journal, Apr. 2003, Null, Null

GALNT3, a gene associated with hyperphosphatemic familial tumoral calcinosis, is transcriptionally regulated by extracellular phosphate and modulates matrix metalloproteinase activity.
Chefetz Ilana, Kohno Kimitoshi, Izumi Hiroto, Uitto Jouni, Richard Gabriele, Sprecher Eli
Biochimica et biophysica acta, Jan. 2009, Null, Null

Expression and cellular localization of dbpC/Contrin in germ cell tumor cell lines.
Yoshida Takeshi, Izumi Hiroto, Uchiumi Takeshi, Sasaguri Yasuyuki, Tanimoto Akihide, Matsumoto Tetsuro, Naito Seiji, Kohno Kimitoshi
Biochimica et biophysica acta, Null, Null

Structural and functional characterization of two human V-ATPase subunit gene promoters.
Izumi Hiroto, Ise Tomoko, Murakami Tadashi, Torigoe Takayuki, Ishiguchi Hiroshi, Uramoto Hidetaka, Yoshida Yoichiro, Yoshida Takeshi, Tanabe Mizuho, Kohno Kimitoshi
Biochimica et biophysica acta, Jul. 2003, Null, Null

Expression of UDP-N-acetyl-alpha-D-galactosamine-polypeptide galNAc N-acetylgalactosaminyl transferase-3 in relation to differentiation and prognosis in patients with colorectal carcinoma.
Shibao Kazunori, Izumi Hiroto, Nakayama Yoshifumi, Ohta Ryo, Nagata Naoki, Nomoto Minoru, Matsuo Ken-ichi, Yamada Yuji, Kitazato Kenji, Itoh Hideaki, Kohno Kimitoshi
Cancer, Apr. 2002, Null, Null

N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression.
Hosoi Fumihito, Izumi Hiroto, Kawahara Akihiko, Murakami Yuichi, Kinoshita Hisafumi, Kage Masayoshi, Nishio Kazuto, Kohno Kimitoshi, Kuwano Michihiko, Ono Mayumi
Cancer research, Jun. 2009, Null, Null

Twist promotes tumor cell growth through YB-1 expression.
Shiota Masaki, Izumi Hiroto, Onitsuka Takamitsu, Miyamoto Naoya, Kashiwagi Eiji, Kidani Akihiko, Yokomizo Akira, Naito Seiji, Kohno Kimitoshi
Cancer research, Jan. 2008, Null, Null

Activating transcription factor 4 increases the cisplatin resistance of human cancer cell lines.
Tanabe Mizuho, Izumi Hiroto, Ise Tomoko, Higuchi Shun, Yamori Takao, Yasumoto Kosei, Kohno Kimitoshi
Cancer research, Dec. 2003, Null, Null

P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA.
Yoshida Yoichiro, Izumi Hiroto, Torigoe Takayuki, Ishiguchi Hiroshi, Itoh Hideaki, Kang Dongchon, Kohno Kimitoshi
Cancer research, Jul. 2003, Null, Null

Ets regulates peroxiredoxin1 and 5 expressions through their interaction with the high-mobility group protein B1.
Shiota Masaki, Izumi Hiroto, Miyamoto Naoya, Onitsuka Takamitsu, Kashiwagi Eiji, Kidani Akihiko, Hirano General, Takahashi Mayu, Ono Mayumi, Kuwano Michihiko, Naito Seiji, Sasaguri Yasuyuki, Kohno Kimitoshi
Cancer science, Oct. 2008, Reviewed, Null

Ets regulates peroxiredoxin1 and 5 expressions through their interaction with the high-mobility group protein B1.
Shiota Masaki, Izumi Hiroto, Miyamoto Naoya, Onitsuka Takamitsu, Kashiwagi Eiji, Kidani Akihiko, Hirano General, Takahashi Mayu, Ono Mayumi, Kuwano Michihiko, Naito Seiji, Sasaguri Yasuyuki, Kohno Kimitoshi
Cancer science, Oct. 2008, Null, Null

DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation.
Niina Ichiro, Uchiumi Takeshi, Izumi Hiroto, Torigoe Takayuki, Wakasugi Tetsuro, Igarashi Tomonori, Miyamoto Naoya, Onitsuka Takamitsu, Shiota Masaki, Okayasu Ryuichi, Chijiiwa Kazuo, Kohno Kimitoshi
Cancer science, Jun. 2007, Null, Null

Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis.
Kimura Yusuke N, Watari Kosuke, Fotovati Abbas, Hosoi Fumihito, Yasumoto Kosei, Izumi Hiroto, Kohno Kimitoshi, Umezawa Kazuo, Iguchi Haruo, Shirouzu Kazuo, Takamori Sinzo, Kuwano Michihiko, Ono Mayumi
Cancer science, Dec. 2007, Null, Null

Prognostic significance of UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-3 (GalNAc-T3) expression in patients with gastric carcinoma.
Onitsuka Koji, Shibao Kazunori, Nakayama Yoshifumi, Minagawa Noritaka, Hirata Keiji, Izumi Hiroto, Matsuo Ken-ichi, Nagata Naoki, Kitazato Kenji, Kohno Kimitoshi, Itoh Hideaki
Cancer science, Jan. 2003, Null, Null

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy.
Izumi Hiroto, Torigoe Takayuki, Ishiguchi Hiroshi, Uramoto Hidetaka, Yoshida Yoichiro, Tanabe Mizuho, Ise Tomoko, Murakami Tadashi, Yoshida Takeshi, Nomoto Minoru, Kohno Kimitoshi
Cancer treatment reviews, Dec. 2003, Null, Null

Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel.
Fujita Tomoyuki, Ito Ken-ichi, Izumi Hiroto, Kimura Morihiko, Sano Muneaki, Nakagomi Hiroshi, Maeno Kazuma, Hama Yoshihisa, Shingu Kiyoshi, Tsuchiya Shin-ichi, Kohno Kimitoshi, Fujimori Minoru
Clinical cancer research : an official journal of the American Association for Cancer Research, Dec. 2005, Null, Null

Cisplatin resistance and transcription factors.
Torigoe Takayuki, Izumi Hiroto, Ishiguchi Hiroshi, Yoshida Yoichiro, Tanabe Mizuho, Yoshida Takeshi, Igarashi Tomonori, Niina Ichiro, Wakasugi Tetsuro, Imaizumi Takuya, Momii Yasutomo, Kuwano Michihiko, Kohno Kimitoshi
Current medicinal chemistry. Anti-cancer agents, Jan. 2005, Null, Null

Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells.
Basaki Yuji, Taguchi Ken-Ichi, Izumi Hiroto, Murakami Yuichi, Kubo Takuya, Hosoi Fumihito, Watari Kosuke, Nakano Kenji, Kawaguchi Hidetoshi, Ohno Shinji, Kohno Kimitoshi, Ono Mayumi, Kuwano Michihiko
European journal of cancer (Oxford, England : 1990), Mar. 2010, Null, Null

Transcription factors and drug resistance.
Kohno Kimitoshi, Uchiumi Takeshi, Niina Ichiro, Wakasugi Tetsuro, Igarashi Tomonori, Momii Yasutomo, Yoshida Takeshi, Matsuo Ken-Ichi, Miyamoto Naoya, Izumi Hiroto
European journal of cancer (Oxford, England : 1990), Nov. 2005, Null, Null

ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA.
Ishiguchi Hiroshi, Izumi Hiroto, Torigoe Takayuki, Yoshida Yoichiro, Kubota Hiroshi, Tsuji Sadatoshi, Kohno Kimitoshi
International journal of cancer, Oct. 2004, Null, Null

Thioredoxin2 enhances the damaged DNA binding activity of mtTFA through direct interaction.
Kidani Akihiko, Izumi Hiroto, Yoshida Yoichiro, Kashiwagi Eiji, Ohmori Haruki, Tanaka Tsuneo, Kuwano Michihiko, Kohno Kimitoshi
International journal of oncology, Dec. 2009, Null, Null

Nipradilol and timolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress.
Miyamoto Naoya, Izumi Hiroto, Miyamoto Rie, Kubota Toshiaki, Tawara Akihiko, Sasaguri Yasuyuki, Kohno Kimitoshi
Investigative ophthalmology & visual science, Jun. 2009, Null, Null

Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance.
Miyamoto Naoya, Izumi Hiroto, Noguchi Takako, Nakajima Yoshihiro, Ohmiya Yoshihiro, Shiota Masaki, Kidani Akihiko, Tawara Akihiko, Kohno Kimitoshi
The Journal of biological chemistry, Jun. 2008, Null, Null

YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation.
Uchiumi Takeshi, Fotovati Abbas, Sasaguri Takakazu, Shibahara Kohtaro, Shimada Tatsuo, Fukuda Takao, Nakamura Takanori, Izumi Hiroto, Tsuzuki Teruhisa, Kuwano Michihiko, Kohno Kimitoshi
The Journal of biological chemistry, Dec. 2006, Null, Null

DNA topoisomerase II poison TAS-103 transactivates GC-box-dependent transcription via acetylation of Sp1.
Torigoe Takayuki, Izumi Hiroto, Wakasugi Tetsuro, Niina Ichiro, Igarashi Tomonori, Yoshida Takeshi, Shibuya Izumi, Chijiiwa Kazuo, Matsuo Ken-ichi, Itoh Hideaki, Kohno Kimitoshi
The Journal of biological chemistry, Jan. 2005, Null, Null

Enhanced expression of the human vacuolar H+-ATPase c subunit gene (ATP6L) in response to anticancer agents.
Torigoe Takayuki, Izumi Hiroto, Ishiguchi Hiroshi, Uramoto Hidetaka, Murakami Tadashi, Ise Tomoko, Yoshida Yoichiro, Tanabe Mizuho, Nomoto Minoru, Itoh Hideaki, Kohno Kimitoshi
The Journal of biological chemistry, Sep. 2002, Null, Null

p73 Interacts with c-Myc to regulate Y-box-binding protein-1 expression.
Uramoto Hidetaka, Izumi Hiroto, Ise Tomoko, Tada Mitsuhiro, Uchiumi Takeshi, Kuwano Michihiko, Yasumoto Kosei, Funa Keiko, Kohno Kimitoshi
The Journal of biological chemistry, Aug. 2002, Null, Null

Mina53, a novel c-Myc target gene, is frequently expressed in lung cancers and exerts oncogenic property in NIH/3T3 cells.
Komiya Kazutoshi, Sueoka-Aragane Naoko, Sato Akemi, Hisatomi Takashi, Sakuragi Toru, Mitsuoka Masahiro, Sato Toshimi, Hayashi Shinichiro, Izumi Hiroto, Tsuneoka Makoto, Sueoka Eisaburo
Journal of cancer research and clinical oncology, Mar. 2010, Null, Null

Expression of GalNAc-T3 and its relationships with clinicopathological factors in 61 extrahepatic bile duct carcinomas analyzed using stepwise sections - special reference to its association with lymph node metastases-.
Inoue Takahiro, Eguchi Takashi, Oda Yoshinao, Nishiyama Kenichi, Fujii Kei, Izumi Hiroto, Kohno Kimitoshi, Yamaguchi Koji, Tanaka Masao, Tsuneyoshi Masazumi
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Feb. 2007, Null, Null

The role of nuclear Y-box binding protein 1 as a global marker in drug resistance.
Kuwano Michihiko, Oda Yoshinao, Izumi Hiroto, Yang Song-Ju, Uchiumi Takeshi, Iwamoto Yukihide, Toi Masakazu, Fujii Teruhiko, Yamana Hideaki, Kinoshita Hisafumi, Kamura Toshiharu, Tsuneyoshi Masazumi, Yasumoto Kosei, Kohno Kimitoshi
Molecular cancer therapeutics, Nov. 2004, Null, Null

Oncogenic Ras-induced morphologic change is through MEK/ERK signaling pathway to downregulate Stat3 at a posttranslational level in NIH3T3 cells.
Yeh Hsuan-Heng, Wu Chin-Han, Giri Raghavaraju, Kato Ken, Kohno Kimitoshi, Izumi Hiroto, Chou Cheng-Yang, Su Wu-Chou, Liu Hsiao-Sheng
Neoplasia (New York, N.Y.), Jan. 2008, Null, Null

Low pH enhances Sp1 DNA binding activity and interaction with TBP.
Torigoe Takayuki, Izumi Hiroto, Yoshida Yoichiro, Ishiguchi Hiroshi, Okamoto Takashi, Itoh Hideaki, Kohno Kimitoshi
Nucleic acids research, Aug. 2003, Null, Null

Binding of RNA to p53 regulates its oligomerization and DNA-binding activity.
Yoshida Yoichiro, Izumi Hiroto, Torigoe Takayuki, Ishiguchi Hiroshi, Yoshida Takeshi, Itoh Hideaki, Kohno Kimitoshi
Oncogene, May 2004, Null, Null

p73gamma transactivates the p21 promoter through preferential interaction with the p300/CBP-associated factor in human prostate cancer cells.
Momii Yasutomo, Izumi Hiroto, Shiota Masaki, Onitsuka Takamitsu, Abe Tatsuya, Kobayashi Hidenori, Miyamoto Naoya, Uchiumi Takeshi, Kohno Kimitoshi
Oncology reports, Aug. 2007, Null, Null

Ⅱ　疾患の病因と病態　8 ナノ粒子と呼吸器疾患
森本泰夫, 和泉弘人, Contributor
中外医学社, Jan. 2014
978-4-498-13012-8

高濃度化学物質暴露に起因する中毒性疾患　アスベストを含む職業的粉じん吸入による肺障害
森本泰夫, 和泉弘人, 島田学, Contributor
医薬ジャーナル社, Jul. 2015
1344-6932

吸入ばく露による化学物質の肺有害性評価
森本泰夫, 和泉弘人, 島田学, 久保優, Contributor
日本エアロゾル学会, Sep. 2017

多糖核酸複合体の発見と核酸医薬DDへの応用
隅谷　和樹,　和泉　弘人,　望月　慎一,　櫻井　和朗, Joint work
シーエムシー出版, Mar. 2022
9784781316598

ナノ粒子
森本泰夫, 和泉弘人, 友永泰介, 吉浦由貴子, 矢寺和博, Contributor
最新医学社, Jul. 2015
0370-8241

ナノマテリアルの吸入ばく露と生体影響
森本　泰夫, 和泉　弘人, 西田　千夏, Joint work
公益財団法人　産業医学振興財団, May 2018

化学物質の肺有害性評価
森本泰夫, 和泉弘人, 島田学, 久保優, Contributor
（株）技術情報協会, 2017

Vacuolar H+ -ATPase:Functional Mechanism and Potential as a Target for Cancer Chemotherapy
Hiroto Izumi, Kimitoshi Kohno, Contributor
Pan Stanford Publishing Pte.Ltd, Feb. 2014
978-981-4411-92-9