2020年04月
文部科学省, 2020年文部科学大臣表彰（科学技術分野 研究部門）

2009年09月
日本神経科学学会, 日本神経科学学会奨励賞
足立弘明

Heart rate variability in adults with mild traumatic brain injury: a population-based cross-sectional study
Enkhjin Bat-Erdene; Enkhnaran Tumurbaatar; Gantsetseg Tumur-Ochir; Battuvshin Lkhagvasuren; Tsolmon Jadamba; Hiroaki Adachi
Clinical Neurology and Neurosurgery, 2026年03月

Utility of Locus Coeruleus Signal Intensity on High-resolution T1-weighted MR Imaging with Magnetization Transfer for Differentiating Parkinson's Disease from Atypical Parkinsonism
Hiroaki Adachi
Magnetic Resonance in Medical Sciences, 2026年

CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer's disease
Qiang Qiang; Loren Skudder-Hill; Tomoko Toyota; Zhe Huang; Wenshi Wei; Hiroaki Adachi
Neurobiology of Aging, 2025年06月

Usefulness of the Gold Coast criteria in diagnosing fast-progressing amyotrophic lateral sclerosis
Keiko Ohnari; Kosuke Mafune; Hiroaki Adachi
Journal of the Neurological Sciences, 2025年04月

脳梗塞後に生じた遅発性低酸素後白質脳症の1例
楫野 貴一; 二ツ矢 浩一郎; 井手 智; 村上 優; 吉松 悠太; 穴井 健太; 青木 隆敏; 豊田 知子; 足立 弘明; 篠原 誼; 山本 淳考
Japanese Journal of Radiology, 2025年02月

A multicenter cross-sectional study to elucidate altered resting-state functional connectivity of the insular cortex in anorexia nervosa, segmented by functional localization
Hiroaki Adachi
Scientific Reports, 2025年

¹⁸F-FDG PET for the differential diagnosis of Alzheimer's disease and frontotemporal lobar degeneration: A multicenter prospective study in Japan
Hiroaki Adachi
Journal of Alzheimer's Disease, 2025年

Hippocampal Sclerosis After Legionnaires' Disease: A Case Report.
Atsuko Ikenouchi; Satoru Ide; Gaku Hayasaki; Hiroaki Adachi; Reiji Yoshimura
Cureus, 2024年12月

Fasciculation potentials are related to the prognosis of amyotrophic lateral sclerosis
Keiko Ohnari; Kosuke Mafune; Hiroaki Adachi
PLOS ONE, 2024年11月

Evaluation of Hand-Arm Vibration Syndrome Owing to Nerve Conduction Study and Cumulative Exposure Index—A 2.5-Year Cohort Study
Kazunori Ikegami; Keiko Ohnari; Taiki Shirasaka; Satoshi Michii; Hidetaka Yoshitake; Ryosuke Sugano; Hiroki Nozawa; Masayuki Hasegawa; Hajime Ando; Akira Ogami; Hiroaki Adachi
Journal of Occupational & Environmental Medicine, 2024年08月

Usefulness of Olfactory Bulb Measurement in 3D-FIESTA in Differentiating Parkinson Disease from Atypical Parkinsonism
Satoru Ide; Yu Murakami; Koichiro Futatsuya; Kenta Anai; Yuta Yoshimatsu; Satoshi Fukumitsu; Jun Tsukamoto; Tomoyo Hashimoto; Hiroaki Adachi; Issei Ueda; Shingo Kakeda; Takatoshi Aoki
American Journal of Neuroradiology, 2024年06月

Multicenter, randomized, double-blind, placebo-controlled phase 3 study of mogamulizumab with open-label extension study in a minimum number of patients with human T-cell leukemia virus type-1-associated myelopathy
Tomoo Sato; Masahiro Nagai; Osamu Watanabe; Tatsuro Misu; Norihiro Takenouchi; Ryuichi Ohkubo; Satoshi Ishihara; Yoshio Tsuboi; Masahisa Katsuno; Masanori Nakagawa; Takuya Matsushita; Yasuhiro Aso; Eiji Matsuura; Takashi Tokashiki; Akihiro Mukaino; Hiroaki Adachi; Kaoru Nakanishi; Yusuke Yamaguchi; Saaya Yamaguchi; Yoshihisa Yamano
Journal of Neurology, 2024年06月

Complete nanopore repeat sequencing of SCA27B (GAA-FGF14 ataxia) in Japanese.
Satoko Miyatake; Hiroshi Doi; Hiroaki Yaguchi; Eriko Koshimizu; Naoki Kihara; Tomoyasu Matsubara; Yasuko Mori; Kenjiro Kunieda; Yusaku Shimizu; Tomoko Toyota; Shinichi Shirai; Masaaki Matsushima; Masaki Okubo; Taishi Wada; Misako Kunii; Ken Johkura; Ryosuke Miyamoto; Yusuke Osaki; Takabumi Miyama; Mai Satoh; Atsushi Fujita; Yuri Uchiyama; Naomi Tsuchida; Kazuharu Misawa; Kohei Hamanaka; Haruka Hamanoue; Takeshi Mizuguchi; Hiroyuki Morino; Yuishin Izumi; Takayoshi Shimohata; Kunihiro Yoshida; Hiroaki Adachi; Fumiaki Tanaka; Ichiro Yabe; Naomichi Matsumoto
Journal of neurology, neurosurgery, and psychiatry, 2024年05月

Dramatic improvement in refractory myasthenia gravis with eculizumab treatment: a case report
Hiroaki Adachi
Journal of Neurology, 2024年05月

CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer's disease
Hiroaki Adachi
Journal of the Neurological Sciences, 2024年02月

Comprehensive alteration in white matter microstructure in women with anorexia nervosa
Hiroaki Adachi
Psychotherapy and Psychosomatics, 2024年

PATIENT WITH PARKINSON’S DISEASE AND DEPRESSIVE SYMPTOMS ASSOCIATED WITH IMPULSE CONTROL DISORDER
Migita, K.; Okamoto, N.; Ikenouchi, A.; Kijima, R.; Hashimoto, T.; Adachi, H.; Yoshimura, R.
Psychiatria Danubina, 2024年

Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy.
Tomoki Hirunagi; Hideaki Nakatsuji; Kentaro Sahashi; Mikiyasu Yamamoto; Madoka Iida; Genki Tohnai; Naohide Kondo; Shinichiro Yamada; Ayuka Murakami; Seiya Noda; Hiroaki Adachi; Gen Sobue; Masahisa Katsuno
Journal of cachexia, sarcopenia and muscle, 2023年11月

CSF 14-3-3β is associated with progressive cognitive decline in Alzheimer’s disease
Qiang Qiang; Loren Skudder-Hill; Tomoko Toyota; Zhe Huang; Wenshi Wei; Hiroaki Adachi
Brain Communications, 2023年11月

Complete SAMD12 repeat expansion sequencing in a four-generation BAFME1 family with anticipation.
Takeshi Mizuguchi; Tomoko Toyota; Eriko Koshimizu; Shinichi Kameyama; Hiromi Fukuda; Naomi Tsuchida; Yuri Uchiyama; Kohei Hamanaka; Atsushi Fujita; Kazuharu Misawa; Satoko Miyatake; Hiroaki Adachi; Naomichi Matsumoto
Journal of human genetics, 2023年08月

抗パーキンソン病薬中止によって衝動制御障害(露出障害)に伴う抑うつ症状が改善した1例
右田 香奈枝; 岡本 直通; 池ノ内 篤子; 橋本 智代; 足立 弘明; 吉村 玲児
精神神経学雑誌, 2023年06月

Systematic Reduction of Gray Matter Volume in Anorexia Nervosa, but Increase With Clinical Symptoms in the Prefrontal and Posterior Insular Cortices: A Multicenter Neuroimaging Study
Atsushi Sekiguchi; Keima TOSE; Tsunehiko Takamura; Masanori Isobe; Yoshiyuki Hirano; Yasuhiro SATO; Naoki Kodama; Kazufumi YOSHIHARA; Norihide MAIKUSA; Yoshiya Moriguchi; Tomomi NODA; Ryo Mishima; Michiko KAWABATA; Shun'ichi NOMA; Shu TAKAKURA; Motoharu GONDO; Shingo Kakeda; Masatoshi Takahashi; Satoru Ide; Hiroaki Adachi; Sayo HAMATANI; Rio KAMASHITA; Koji MATSUMOTO; Michiko NAKAZATO; Noriko NUMATA; Yumi HAMAMOTO; Tomotaka SHOJI; Tomohiko MURATSUBAKI; Motoaki SUGIURA; Toshiya Murai; Shin Fukudo
Molecular psychiatry, 2023年02月

Superior cerebellar peduncle atrophy of progressive supranuclear palsy on phase difference enhanced imaging: a comparison with Parkinson’s disease
Miyata M; Kakeda S; Yoneda T; Ide S; Okada K; Adachi H; Korogi Y
Neuroradiology, 2023年01月, 査読あり, 招待無し

Optic radiation atrophy in Lewy body disease with visual hallucination on phase difference enhanced magnetic resonance images
Mari Miyata; Shingo Kakeda; Tetsuya Yoneda; Satoru Ide; Kazumasa Okada; Hiroaki Adachi; Yukunori Korogi
Scientific Reports, 2022年11月

Rapid and comprehensive diagnostic method for repeat expansion diseases using nanopore sequencing
Satoko Miyatake; Eriko Koshimizu; Atsushi Fujita; Hiroshi Doi; Masaki Okubo; Taishi Wada; Kohei Hamanaka; Naohisa Ueda; Hitaru Kishida; Gaku Minase; Atsuhiro Matsuno; Minori Kodaira; Katsuhisa Ogata; Rumiko Kato; Atsuhiko Sugiyama; Ayako Sasaki; Takabumi Miyama; Mai Satoh; Yuri Uchiyama; Naomi Tsuchida; Haruka Hamanoue; Kazuharu Misawa; Kiyoshi Hayasaka; Yoshiki Sekijima; Hiroaki Adachi; Kunihiro Yoshida; Fumiaki Tanaka; Takeshi Mizuguchi; Naomichi Matsumoto
npj Genomic Medicine, 2022年10月

CSF GAP-43 as a biomarker of synaptic dysfunction is associated with tau pathology in Alzheimer’s disease
Qiang Qiang; Loren Skudder-Hill; Tomoko Toyota; Wenshi Wei; Hiroaki Adachi
Scientific Reports, 2022年10月, 査読あり
ラスト(シニア)オーサー, 責任著者

Neuropsychiatric systemic lupus erythematosus detected using extravascular spillage signal on dynamic magnetic resonance imaging (Ktrans).
Yuya Fujita; Shigeru Iwata; Kazuhisa Nakano; Hiroaki Adachi; Yoshiya Tanaka
Rheumatology (Oxford, England), 2021年10月

Erratum to: Complete sequencing of expanded SAMD12 repeats by long-read sequencing and Cas9-mediated enrichment.
Takeshi Mizuguchi; Tomoko Toyota; Satoko Miyatake; Satomi Mitsuhashi; Hiroshi Doi; Yosuke Kudo; Hitaru Kishida; Noriko Hayashi; Rie S Tsuburaya; Masako Kinoshita; Tetsuhiro Fukuyama; Hiromi Fukuda; Eriko Koshimizu; Naomi Tsuchida; Yuri Uchiyama; Atsushi Fujita; Atsushi Takata; Noriko Miyake; Mitsuhiro Kato; Fumiaki Tanaka; Hiroaki Adachi; Naomichi Matsumoto
Brain : a journal of neurology, 2021年09月

Unclassified subtype of Guillain-Barré syndrome is associated with quick recovery.
Keiko Ohnari; Kazumasa Okada; Kosuke Mafune; Susumu Kusunoki; Hiroaki Adachi
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021年09月

Complete sequencing of expanded SAMD12 repeats by long-read sequencing and Cas9-mediated enrichment.
Takeshi Mizuguchi; Tomoko Toyota; Satoko Miyatake; Satomi Mitsuhashi; Hiroshi Doi; Yosuke Kudo; Hitaru Kishida; Noriko Hayashi; Rie S Tsuburaya; Masako Kinoshita; Tetsuhiro Fukuyama; Hiromi Fukuda; Eriko Koshimizu; Naomi Tsuchida; Yuri Uchiyama; Atsushi Fujita; Atsushi Takata; Noriko Miyake; Mitsuhiro Kato; Fumiaki Tanaka; Hiroaki Adachi; Naomichi Matsumoto
Brain : a journal of neurology, 2021年05月

Electrophysiological findings in neuromyelitis optica spectrum disorder.
Hiroaki Adachi
Online Journal of Neurology and Brain Disorders, 2021年01月

Olfactory-cognitive index distinguishes involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of medial temporal areas, and global brain, as in Kihon Checklist frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease
Iritani, Osamu; Okuno, Tazuo; Miwa, Takaki; Makizako, Hyuma; Okutani, Fumino; Kashibayashi, Tetsuo; Suzuki, Kumiko; Hara, Hideo; Mori, Eri; Omoto, Shusaku; Suzuki, Hirokazu; Shibata, Minori; Adachi, Hiroaki; Kondo, Kenji; Umeda-Kameyama, Yumi; Kodera, Kumie; Morimoto, Shigeto
Geriatrics & Gerontology International, 2021年01月

Eating Disorder Neuroimaging Initiative (EDNI): a multicentre prospective cohort study protocol for elucidating the neural effects of cognitive–behavioural therapy for eating disorders
Hamatani, Sayo; Hirano, Yoshiyuki; Sugawara, Ayako; Isobe, Masanori; Kodama, Naoki; Yoshihara, Kazufumi; Moriguchi, Yoshiya; Ando, Tetsuya; Endo, Yuka; Takahashi, Jumpei; Nohara, Nobuhiro; Takamura, Tsunehiko; Hori, Hiroaki; Noda, Tomomi; Tose, Keima; Watanabe, Keita; Adachi, Hiroaki; Gondo, Motoharu; Takakura, Shu; Fukudo, Shin; Shimizu, Eiji; Yoshiuchi, Kazuhiro; Sato, Yasuhiro; Sekiguchi, Atsushi
BMJ Open, 2021年

Signal intensity of cerebral gyri in corticobasal syndrome on phase difference enhanced magnetic resonance images: Comparison of progressive supranuclear palsy and Parkinson's disease.
Mari Miyata; Shingo Kakeda; Tetsuya Yoneda; Satoru Ide; Kazumasa Okada; Hiroaki Adachi; Yukunori Korogi
Journal of the neurological sciences, 2020年12月

Hippocampal sclerosis without visually detectable hippocampal MRI abnormalities: automated subfield volumetric analysis.
Hiromi Masaki; Keita Watanabe; Shingo Kakeda; Satoru Ide; Kohichiro Sugimoto; Issei Ueda; Toshihiko Hamamura; Sachi Hisanaga; Tomoko Toyota; Naoki Akamatsu; Shohei Shimajiri; Junkoh Yamamoto; Shigeru Nishizawa; Hiroaki Adachi; Yukunori Korogi
Japanese journal of radiology, 2020年11月

レーザースペックルフローグラフィーを用いた累積振動ばく露による振動工具取扱者の手指末梢循環の評価
吉武 英隆; 道井 聡史; 白坂 泰樹; 菅野 良介; 安藤 肇; 野澤 弘樹; 長谷川 将之; 池上 和範; 大成 圭子; 足立 弘明; 大神 明
労働安全衛生研究, 2020年09月

Muscle BDNF improves synaptic and contractile muscle strength in Kennedy's disease mice in a muscle‐type specific manner
Katherine Halievski; Youfen Xu; Yazeed W. Haddad; Yu Ping Tang; Shinichiro Yamada; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S. Marc Breedlove; Cynthia L. Jordan
The Journal of Physiology, 2020年07月

Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation.
Eiko N Minakawa; Helena Akiko Popiel; Masayoshi Tada; Toshiaki Takahashi; Hiroshi Yamane; Yuji Saitoh; Yasuo Takahashi; Daisaku Ozawa; Akiko Takeda; Toshihide Takeuchi; Yuma Okamoto; Kazuhiro Yamamoto; Mari Suzuki; Hiromi Fujita; Chiyomi Ito; Hiroko Yagihara; Yuko Saito; Kei Watase; Hiroaki Adachi; Masahisa Katsuno; Hideki Mochizuki; Kentaro Shiraki; Gen Sobue; Tatsushi Toda; Keiji Wada; Osamu Onodera; Yoshitaka Nagai
Brain : a journal of neurology, 2020年06月

Facial nerve atrophy in patients with amyotrophic lateral sclerosis: Evaluation with fast imaging employing steady-state acquisition (FIESTA).
Mari Miyata; Shingo Kakeda; Tomoyo Hashimoto; Satoru Ide; Kazumasa Okada; Hiroaki Adachi; Yukunori Korogi
Journal of magnetic resonance imaging : JMRI, 2020年03月

The facial nerve atrophy with spinal and bulbar muscular atrophy patients (SBMA): Three case reports with 3D fast imaging employing steady-state acquisition (FIESTA)
Mari Miyata; Shingo Kakeda; Tomoyo Hashimoto; Yukunori Korogi; Hiroaki Adachi
Journal of the Neurological Sciences, 2019年11月

壊死性筋症の臨床・針筋電図所見と治療の特徴
橋本 智代; 先成 祐介; 小畑 雅子; 岩中 行己男; 大成 圭子; 岡田 和将; 西野 一三; 足立 弘明
臨床神経学, 2019年11月, 査読あり, 招待無し

Potential usefulness of signal intensity of cerebral gyri on quantitative susceptibility mapping for discriminating corticobasal degeneration from progressive supranuclear palsy and Parkinson's disease.
Mari Miyata; Shingo Kakeda; Yasuko Toyoshima; Satoru Ide; Kazumasa Okada; Hiroaki Adachi; Yi Wang; Yukunori Korogi
Neuroradiology, 2019年11月, 査読あり, 招待無し

軸索型ポリニューロパチーで発症し、長期経過後に舞踏運動が出現したMcLeod症候群の1例
山本 燎; 大成 圭子; 先成 裕介; 橋本 智代; 西野 一三; 足立 弘明; 岡田 和将
臨床神経学, 2019年10月, 査読あり, 招待無し

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy.
Madoka Iida; Kentaro Sahashi; Naohide Kondo; Hideaki Nakatsuji; Genki Tohnai; Yutaka Tsutsumi; Seiya Noda; Ayuka Murakami; Kazunari Onodera; Yohei Okada; Masahiro Nakatochi; Yuka Tsukagoshi Okabe; Shinobu Shimizu; Masaaki Mizuno; Hiroaki Adachi; Hideyuki Okano; Gen Sobue; Masahisa Katsuno
Nature communications, 2019年09月, 査読あり, 招待無し

Detection of dentate nuclei abnormality in a patient with dentatorubral-pallidoluysian atrophy using the quantitative susceptibility mapping
Satoru Ide; Shingo Kakeda; Hiroaki Adachi; Mari Miyata; Yukio Iwanaka; Kazumasa Okada; Yukunori Korogi
Journal of the Neurological Sciences, 2019年08月, 査読あり, 招待無し

Potential usefulness of signal intensity of cerebral gyri on quantitative susceptibility mapping for discriminating corticobasal degeneration from progressive supranuclear palsy and Parkinson’s disease
Hiroaki Adachi
Neuroradiology, 2019年07月

振動工具の取扱い者の神経伝導検査による早期スクリーニングの検討
池上 和範; 大成 圭子; 道井 聡; 白坂 泰樹; 安藤 肇; 菅野 良介; 野澤 弘樹; 足立 弘明; 大神 明
産業衛生学雑誌, 2019年05月

DNA methylation inhibitor attenuates polyglutamine‐induced neurodegeneration by regulating Hes5
Naohide Kondo; Genki Tohnai; Kentaro Sahashi; Madoka Iida; Mayumi Kataoka; Hideaki Nakatsuji; Yutaka Tsutsumi; Atsushi Hashizume; Hiroaki Adachi; Haruki Koike; Keiko Shinjo; Yutaka Kondo; Gen Sobue; Masahisa Katsuno
EMBO Molecular Medicine, 2019年05月, 査読あり, 招待無し

Tandem-genotypes: robust detection of tandem repeat expansions from long DNA reads.
Satomi Mitsuhashi; Martin C Frith; Takeshi Mizuguchi; Satoko Miyatake; Tomoko Toyota; Hiroaki Adachi; Yoko Oma; Yoshihiro Kino; Hiroaki Mitsuhashi; Naomichi Matsumoto
Genome biology, 2019年03月, 査読あり, 招待無し

Detecting a long insertion variant in SAMD12 by SMRT sequencing: implications of long-read whole-genome sequencing for repeat expansion diseases.
Takeshi Mizuguchi; Tomoko Toyota; Hiroaki Adachi; Noriko Miyake; Naomichi Matsumoto; Satoko Miyatake
Journal of human genetics, 2019年03月, 査読あり, 招待無し

Disease Affects Bdnf Expression in Synaptic and Extrasynaptic Regions of Skeletal Muscle of Three SBMA Mouse Models.
Katherine Halievski; Samir R Nath; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S Marc Breedlove; Andrew P Lieberman; Cynthia L Jordan
International journal of molecular sciences, 2019年03月, 査読あり, 招待無し

振動工具の取り扱いによる末梢神経障害
大成 圭子; 池上 和範; 白坂 泰樹; 安藤 肇; 菅野 良介; 野澤 弘樹; 大神 明; 足立 弘明
末梢神経, 2018年12月

抗アセチルコリン受容体抗体と抗低比重リポ蛋白質受容体関連蛋白質4抗体を有する筋萎縮性側索硬化症を伴う遅発性重症筋無力症(Late-onset Myasthenia Gravis Accompanied by Amyotrophic Lateral Sclerosis with Antibodies against the Acetylcholine Receptor and Low-density Lipoprotein Receptor-related Protein 4)
Ohnari Keiko; Okada Kazumasa; Higuchi Osamu; Matsuo Hidenori; Adachi Hiroaki
Internal Medicine, 2018年10月, 査読あり, 招待無し

Late-onset Myasthenia Gravis Accompanied by Amyotrophic Lateral Sclerosis with Antibodies against the Acetylcholine Receptor and Low-density Lipoprotein Receptor-related Protein 4.
Keiko Ohnari; Kazumasa Okada; Osamu Higuchi; Hidenori Matsuo; Hiroaki Adachi
Internal medicine (Tokyo, Japan), 2018年10月, 査読あり, 招待無し

Neural correlates of body comparison and weight estimation in weight-recovered anorexia nervosa: a functional magnetic resonance imaging study.
Kodama N; Moriguchi Y; Takeda A; Maeda M; Ando T; Kikuchi H; Gondo M; Adachi H; Komaki G
BioPsychoSocial medicine, 2018年10月, 査読あり, 招待無し

Pre-clinical symptoms of SBMA may not be androgen-dependent: implications from two SBMA mouse models.
Youfen Xu; Katherine Halievski; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S Marc Breedlove; Cynthia L Jordan
Human molecular genetics, 2018年07月, 査読あり, 招待無し

Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise.
Hiromasa Ninomiya; Nobutaka Ohgami; Reina Oshino; Masashi Kato; Kyoko Ohgami; Xiang Li; Dandan Shen; Machiko Iida; Ichiro Yajima; Charalampos E Angelidis; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Masashi Kato
Hearing research, 2018年06月, 査読あり, 招待無し

Cerebrotendinous Xanthomatosis with Nodular-hypertrophy of the Lumbosacral Roots.
Tomoyo Hashimoto; Yusuke Sennari; Kazumasa Okada; Hiroaki Adachi
Internal medicine (Tokyo, Japan), 2018年06月, 査読あり, 招待無し

Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model.
Shun Mitsui; Asako Otomo; Masahisa Nozaki; Suzuka Ono; Kai Sato; Ryohei Shirakawa; Hiroaki Adachi; Masashi Aoki; Gen Sobue; Hui-Fang Shang; Shinji Hadano
Molecular brain, 2018年05月, 査読あり, 招待無し

【ドラッグリポジショニング-新たな治療戦略】基礎研究とドラッグリポジショニングの治験計画と実施
橋詰 淳; 鈴木 啓介; 足立 弘明; 祖父江 元; 勝野 雅央
カレントテラピー, 2018年05月

皮質基底核変性症の中心溝近傍脳回の信号強度 位相差強調画像(PADRE)によるParkinson病、健常者との比較
宮田 真里; 掛田 伸吾; 森谷 淳二; 井手 智; 渡邉 啓太; 小笠原 篤; 興梠 征典; 足立 弘明; 米田 哲也
Japanese Journal of Radiology, 2018年02月

Coexisting infectious diseases on admission as a risk factor for mechanical ventilation in patients with Guillain-Barré syndrome.
Kobori S; Kubo T; Otani M; Muramatsu K; Fujino Y; Adachi H; Horiguchi H; Fushimi K; Matsuda S
Journal of Epidemiology, 2017年07月, 査読あり, 招待無し

ALSの診断における定量的磁化率マッピング(QSM)の有用性
濱村 俊彦; 掛田 伸吾; 井手 智; 橋本 智代; 渡邉 啓太; 二ツ矢 浩一郎; 森谷 淳二; 興梠 征典; 岡田 和将; 足立 弘明
Japanese Journal of Radiology, 2017年02月

MYOCLONIA CONTINUA IN PRIMARY CNS NATURAL KILLER/T-CELL LYMPHOMA, NASAL TYPE
Tomoko Toyota; Yusuke Sennari; Kazumasa Okada; Ai Kawahara; Junichi Tsukada; Shohei Shimajiri; Hiroaki Adachi
NEUROLOGY, 2017年01月, 査読あり, 招待無し

Zebra sign of precentral gyri in amyotrophic lateral sclerosis: A novel finding using phase difference enhanced (PADRE) imaging-initial results
Shingo Kakeda; Tetsuya Yoneda; Satoru Ide; Mari Miyata; Tomoyo Hashimoto; Koichiro Futatsuya; Keita Watanabe; Atsushi Ogasawara; Junji Moriya; Toru Sato; Kazumasa Okada; Takenori Uozumi; Hiroaki Adachi; Yukunori Korogi
EUROPEAN RADIOLOGY, 2016年11月, 査読あり, 招待無し

HTLV-1関連脊髄症(HAM)に合併した筋炎の一例
清水 栄里; 大成 圭子; 小畑 雅子; 勝又 竜; 岡田 和将; 松浦 英治; 山下 賢; 西野 一三; 足立 弘明
臨床神経学, 2016年10月, 査読あり, 招待無し

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice
Yoshihiro Kino; Chika Washizu; Masaru Kurosawa; Mizuki Yamada; Hiroshi Doi; Toru Takumi; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Geoffrey G. Hicks; Nobutaka Hattori; Tomomi Shimogori; Nobuyuki Nukina
SCIENTIFIC REPORTS, 2016年10月, 査読あり, 招待無し

Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy
Yasuhiro Hijikata; Masahisa Katsuno; Keisuke Suzuki; Atsushi Hashizume; Amane Araki; Shinichiro Yamada; Tomonori Inagaki; Madoka Iida; Seiya Noda; Hirotaka Nakanishi; Haruhiko Banno; Tomoo Mano; Akihiro Hirakawa; Hiroaki Adachi; Hirohisa Watanabe; Masahiko Yamamoto; Gen Sobue
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2016年07月, 査読あり, 招待無し

BIIB021, A SYNTHETIC Hsp90 INHIBITOR, INDUCES MUTANT ATAXIN-1 DEGRADATION THROUGH THE ACTIVATION OF HEAT SHOCK FACTOR 1
Ying Ding; Hiroaki Adachi; Masahisa Katsuno; Kentaro Sahashi; Naohide Kondo; Madoka Iida; Genki Tohnai; Hideaki Nakatsuji; Gen Sobue
NEUROSCIENCE, 2016年07月, 査読あり, 招待無し

The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease
Adachi, H.
No To Hattatsu, 2016年05月, 査読あり, 招待無し

Evoked potentials are useful for diagnosis of neuromyelitis optica spectrum disorder
Keiko Ohnari; Kazumasa Okada; Toshiyuki Takahashi; Kosuke Mafune; Hiroaki Adachi
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2016年05月, 査読あり, 招待無し

Defects in Neuromuscular Transmission May Underlie Motor Dysfunction in Spinal and Bulbar Muscular Atrophy
Youfen Xu; Katherine Halievski; Casey Henley; William D. Atchison; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S. Marc Breedlove; Cynthia L. Jordan
JOURNAL OF NEUROSCIENCE, 2016年05月, 査読あり, 招待無し

抗HMGCR抗体陽性壊死性筋症の一例
先成 裕介; 橋本 智代; 大成 圭子; 岡田 和将; 西野 一三; 鈴木 重明; 足立 弘明
臨床神経学, 2016年04月, 査読あり, 招待無し

Clinically Uncertain Parkinsonian Syndrome(CUPs)における123I-FP-CIT SPECTの初期経験
穴井 健太; 林田 佳子; 上田 一生; 藤井 正美; 掛田 伸吾; 青木 隆敏; 興梠 征典; 岩中 行己男; 足立 弘明
核医学, 2016年02月

Interictal epileptiform discharges in new-onset epilepsy among older adults
Toyota T; Akamatsu N; Tanaka A; Yamano M; Fujino Y; Adachi H
Neurol Clin Neurosci, 2016年01月, 査読あり, 招待無し

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy, 2016年, 査読あり, 招待無し

Juxtacortical Lesions in Multiple Sclerosis: Assessment of Gray Matter Involvement Using Phase Difference-enhanced Imaging (PADRE)
Koichiro Futatsuya; Shingo Kakeda; Tetsuya Yoneda; Issei Ueda; Keita Watanabe; Junji Moriya; Yu Murakami; Satoru Ide; Atsushi Ogasawara; Norihiro Ohnari; Kazumasa Okada; Hiroaki Adachi; Yukunori Korogi
MAGNETIC RESONANCE IN MEDICAL SCIENCES, 2016年, 査読あり, 招待無し

Natural compounds preventing neurodegenerative diseases through autophagic activation
Zhe Huang; Hiroaki Adachi
Journal of UOEH, 2016年, 査読あり, 招待無し

A case of Parkinson's disease following dystonia
Chiharu Yasuda; Takanobu Takei; Takenori Uozumi; Tomoko Toyota; Tomoaki Yuhi; Hiroaki Adachi
Clinical Neurology, 2016年, 査読あり, 招待無し

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration
Ying Ding; Hiroaki Adachi; Masahisa Katsuno; Zhe Huang; Yue-Mei Jiang; Naohide Kondo; Madoka Iida; Genki Tohnai; Hideaki Nakatsuji; Hiroshi Funakoshi; Toshikazu Nakamura; Gen Sobue
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015年12月, 査読あり, 招待無し

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration
Ying Ding; Hiroaki Adachi; Masahisa Katsuno; Zhe Huang; Yue-Mei Jiang; Naohide Kondo; Madoka Iida; Genki Tohnai; Hideaki Nakatsuji; Hiroshi Funakoshi; Toshikazu Nakamura; Gen Sobue
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015年12月, 査読あり, 招待無し

Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy
Kentaro Sahashi; Masahisa Katsuno; Gene Hung; Hiroaki Adachi; Naohide Kondo; Hideaki Nakatsuji; Genki Tohnai; Madoka Iida; C. Frank Bennett; Gen Sobue
HUMAN MOLECULAR GENETICS, 2015年11月, 査読あり, 招待無し

Paraneoplastic neuromyelitis optica spectrum disorder manifesting as intractable nausea and acute cerebellar ataxia associated with lung adenocarcinoma
Masako Kobata; Kazumasa Okada; Tomoyo Hashimoto; Atsuji Matsuyama; Ayumi Uchibori; Toshiyuki Takahashi; Hiroaki Adachi
Neurology and Clinical Neuroscience, 2015年11月, 査読あり, 招待無し

Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy
Kentaro Sahashi; Masahisa Katsuno; Gene Hung; Hiroaki Adachi; Naohide Kondo; Hideaki Nakatsuji; Genki Tohnai; Madoka Iida; C. Frank Bennett; Gen Sobue
HUMAN MOLECULAR GENETICS, 2015年11月, 査読あり, 招待無し

球脊髄性筋萎縮症の中枢神経病態に対する標的治療
佐橋 健太郎; 勝野 雅央; Hung Gene; 足立 弘明; 近藤 直英; 中辻 秀朗; 藤内 玄規; 飯田 円; Bennett C. Frank; 祖父江 元
神経治療学, 2015年09月

DNAメチル化阻害剤による球脊髄性筋萎縮症の治療法開発
近藤 直英; 勝野 雅央; 足立 弘明; 佐橋 健太郎; 中辻 秀朗; 飯田 円; 藤内 玄規; 祖父江 元
神経治療学, 2015年09月

球脊髄性筋萎縮症モデルにおけるタクロリムス誘導体の治療効果
藤内 玄規; 足立 弘明; 勝野 雅央; 佐橋 健太郎; 近藤 直英; 中辻 秀朗; 飯田 円; 祖父江 元
神経治療学, 2015年09月

Human immunoglobulin G suppresses the production of matrix metalloproteinase-9 in peripheral blood mononuclear cells of patients with multiple sclerosis
Kazumasa Okada; Hiroaki Adachi
Clinical and Experimental Neuroimmunology, 2015年08月, 査読あり, 招待無し

Neuronal intranuclear inclusion disease manifesting with new-onset epilepsy in the elderly
Toyota T; Huang Z; Nohara S; Okada K; Kakeda S; Korogi Y; Nakayama T; Sone J; SobueG; Adachi H
Neurol Clin Neurosci, 2015年08月, 査読あり, 招待無し

Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA
Katherine Halievski; Casey L. Henley; Laurel Domino; Jessica E. Poort; Martina Fu; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S. Marc Breedlove; Cynthia L. Jordan
EXPERIMENTAL NEUROLOGY, 2015年07月, 査読あり, 招待無し

Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA
Katherine Halievski; Casey L. Henley; Laurel Domino; Jessica E. Poort; Martina Fu; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S. Marc Breedlove; Cynthia L. Jordan
EXPERIMENTAL NEUROLOGY, 2015年07月, 査読あり, 招待無し

Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy
Kentaro Oki; Katherine Halievski; Laura Vicente; Youfen Xu; Donald Zeolla; Jessica Poort; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; Robert W. Wiseman; S. Marc Breedlove; Cynthia L. Jordan
JOURNAL OF APPLIED PHYSIOLOGY, 2015年04月, 査読あり, 招待無し

Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy
Kentaro Oki; Katherine Halievski; Laura Vicente; Youfen Xu; Donald Zeolla; Jessica Poort; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; Robert W. Wiseman; S. Marc Breedlove; Cynthia L. Jordan
JOURNAL OF APPLIED PHYSIOLOGY, 2015年04月, 査読あり, 招待無し

免疫グロブリン大量静注後に副腎皮質ステロイドとタクロリムス併用が著効した抗SRP抗体陽性壊死性筋症の一例
先成 裕介; 橋本 智代; 松尾 嘉三; 大成 圭子; 岡田 和将; 西野 一三; 鈴木 重明; 足立 弘明
臨床神経学, 2015年02月, 査読あり, 招待無し

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors
Madoka Iida; Masahisa Katsuno; Hideaki Nakatsuji; Hiroaki Adachi; Naohide Kondo; Yu Miyazaki; Genki Tohnai; Kensuke Ikenaka; Hirohisa Watanabe; Masahiko Yamamoto; Ken Kishida; Gen Sobue
HUMAN MOLECULAR GENETICS, 2015年01月, 査読あり, 招待無し

Axonal loss influences the response to rituximab treatment in neuropathy associated with IgM monoclonal gammopathy with anti-myelin-associated glycoprotein antibody
Yuichi Kawagashira; Haruki Koike; Ken Ohyama; Rina Hashimoto; Masahiro Iijima; Hiroaki Adachi; Masahisa Katsuno; Miles Chapman; Michael Lunn; Gen Sobue
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2015年01月, 査読あり, 招待無し

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors
Madoka Iida; Masahisa Katsuno; Hideaki Nakatsuji; Hiroaki Adachi; Naohide Kondo; Yu Miyazaki; Genki Tohnai; Kensuke Ikenaka; Hirohisa Watanabe; Masahiko Yamamoto; Ken Kishida; Gen Sobue
HUMAN MOLECULAR GENETICS, 2015年01月, 査読あり, 招待無し

Axonal loss influences the response to rituximab treatment in neuropathy associated with IgM monoclonal gammopathy with anti-myelin-associated glycoprotein antibody
Yuichi Kawagashira; Haruki Koike; Ken Ohyama; Rina Hashimoto; Masahiro Iijima; Hiroaki Adachi; Masahisa Katsuno; Miles Chapman; Michael Lunn; Gen Sobue
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2015年01月, 査読あり, 招待無し

アンチセンス核酸を用いた球脊髄性筋萎縮症の病態、治療研究
佐橋 健太郎; 勝野 雅央; Hung Gene; 足立 弘明; 近藤 直英; 飯田 円; 中辻 秀朗; 宮崎 雄; 藤内 玄規; Bennett C. Frank; 祖父江 元
臨床神経学, 2014年12月

DNAメチル化阻害剤が球脊髄性筋萎縮症の病態に与える影響の解析
近藤 直英; 勝野 雅央; 足立 弘明; 佐橋 健太郎; 飯田 円; 中辻 秀朗; 宮崎 雄; 藤内 玄規; 祖父江 元
臨床神経学, 2014年12月

TGF-βシグナル阻害による運動ニューロン変性の病態
勝又 竜; 勝野 雅央; 足立 弘明; 佐橋 健太郎; 近藤 直英; 飯田 円; 中辻 秀朗; 宮崎 雄; 藤内 玄規; 祖父江 元
臨床神経学, 2014年12月

Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy
Genki Tohnai; Hiroaki Adachi; Masahisa Katsuno; Hideki Doi; Shinjiro Matsumoto; Naohide Kondo; Yu Miyazaki; Madoka Iida; Hideaki Nakatsuji; Qiang Qiang; Ying Ding; Hirohisa Watanabe; Masahiko Yamamoto; Kenzo Ohtsuka; Gen Sobue
HUMAN MOLECULAR GENETICS, 2014年07月, 査読あり, 招待無し

Antiandrogen Flutamide Protects Male Mice From Androgen-Dependent Toxicity in Three Models of Spinal Bulbar Muscular Atrophy
Kayla J. Renier; Sandra M. Troxell-Smith; Jamie A. Johansen; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; Jason P. Chua; Hong Sun Kim; Andrew P. Lieberman; S. Marc Breedlove; Cynthia L. Jordan
ENDOCRINOLOGY, 2014年07月, 査読あり, 招待無し

Muscle atrophy in chronic inflammatory demyelinating polyneuropathy: a computed tomography assessment
K. Ohyama; H. Koike; M. Katsuno; M. Takahashi; R. Hashimoto; Y. Kawagashira; M. Iijima; H. Adachi; H. Watanabe; G. Sobue
EUROPEAN JOURNAL OF NEUROLOGY, 2014年07月, 査読あり, 招待無し

Antiandrogen Flutamide Protects Male Mice From Androgen-Dependent Toxicity in Three Models of Spinal Bulbar Muscular Atrophy
Kayla J. Renier; Sandra M. Troxell-Smith; Jamie A. Johansen; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; Jason P. Chua; Hong Sun Kim; Andrew P. Lieberman; S. Marc Breedlove; Cynthia L. Jordan
ENDOCRINOLOGY, 2014年07月, 査読あり, 招待無し

Muscle atrophy in chronic inflammatory demyelinating polyneuropathy: a computed tomography assessment
K. Ohyama; H. Koike; M. Katsuno; M. Takahashi; R. Hashimoto; Y. Kawagashira; M. Iijima; H. Adachi; H. Watanabe; G. Sobue
EUROPEAN JOURNAL OF NEUROLOGY, 2014年07月, 査読あり, 招待無し

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy
Jason P. Chua; Satya L. Reddy; Diane E. Merry; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Diane M. Robins; Andrew P. Lieberman
HUMAN MOLECULAR GENETICS, 2014年03月, 査読あり, 招待無し

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy
Jason P. Chua; Satya L. Reddy; Diane E. Merry; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Diane M. Robins; Andrew P. Lieberman
HUMAN MOLECULAR GENETICS, 2014年03月, 査読あり, 招待無し

Potential of a new MRI for visualizing cerebellar involvement in progressive supranuclear palsy
Kazuhiro Hara; Hirohisa Watanabe; Mizuki Ito; Takashi Tsuboi; Hazuki Watanabe; Ryoichi Nakamura; Jo Senda; Naoki Atsuta; Hiroaki Adachi; Ikuko Aiba; Shinji Naganawa; Gen Sobue
PARKINSONISM & RELATED DISORDERS, 2014年02月, 査読あり, 招待無し

Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm
Seiya Tanaka; Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Noriaki Suga; Atsushi Hashizume; Tomoo Mano; Amane Araki; Hirohisa Watanabe; Hiroaki Adachi; Hiroshi Tatsumi; Masahiko Yamamoto; Gen Sobue
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2014年02月, 査読あり, 招待無し

Cortical and subcortical brain atrophy in Parkinson's disease with visual hallucination.
Hirohisa Watanabe; Jo Senda; Shigenori Kato; Mizuki Ito; Naoki Atsuta; Kazuhiro Hara; Takashi Tsuboi; Masahisa Katsuno; Tomohiko Nakamura; Masaaki Hirayama; Hiroaki Adachi; Shinji Naganawa; Gen Sobue
Movement disorders : official journal of the Movement Disorder Society, 2013年10月, 査読あり, 招待無し

Clinicopathological features of neuropathy associated with lymphoma
Minoru Tomita; Haruki Koike; Yuichi Kawagashira; Masahiro Iijima; Hiroaki Adachi; Jun Taguchi; Takenori Abe; Kazuya Sako; Yukiko Tsuji; Masanori Nakagawa; Fumio Kanda; Fusako Takeda; Masashiro Sugawara; Itaru Toyoshima; Naoko Asano; Gen Sobue
BRAIN, 2013年08月, 査読あり, 招待無し

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease
Qiang Qiang; Hiroaki Adachi; Zhe Huang; Yue-Mei Jiang; Masahisa Katsuno; Makoto Minamiyama; Hideki Doi; Shinjiro Matsumoto; Naohide Kondo; Yu Miyazaki; Madoka Iida; Genki Tohnai; Gen Sobue
JOURNAL OF NEUROCHEMISTRY, 2013年07月, 査読あり, 招待無し

RNP2 of RNA Recognition Motif 1 Plays a Central Role in the Aberrant Modification of TDP-43
Shinnosuke Takagi; Yohei Iguchi; Masahisa Katsuno; Shinsuke Ishigaki; Kensuke Ikenaka; Yusuke Fujioka; Daiyu Honda; Jun-ichi Niwa; Fumiaki Tanaka; Hirohisa Watanabe; Hiroaki Adachi; Gen Sobue
PLOS ONE, 2013年06月, 査読あり, 招待無し

RNP2 of RNA Recognition Motif 1 Plays a Central Role in the Aberrant Modification of TDP-43
Shinnosuke Takagi; Yohei Iguchi; Masahisa Katsuno; Shinsuke Ishigaki; Kensuke Ikenaka; Yusuke Fujioka; Daiyu Honda; Jun-ichi Niwa; Fumiaki Tanaka; Hirohisa Watanabe; Hiroaki Adachi; Gen Sobue
PLOS ONE, 2013年06月, 査読あり, 招待無し

p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model
Hideki Doi; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Shinjiro Matsumoto; Naohide Kondo; Yu Miyazaki; Madoka Iida; Genki Tohnai; Qiang Qiang; Fumiaki Tanaka; Toru Yanagawa; Eiji Warabi; Tetsuro Ishii; Gen Sobue
JOURNAL OF NEUROSCIENCE, 2013年05月, 査読あり, 招待無し

Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice.
Minoru Matsuda; Tatsuya Hoshino; Naoki Yamakawa; Kayoko Tahara; Hiroaki Adachi; Gen Sobue; Daisuke Maji; Hironobu Ihn; Tohru Mizushima
The Journal of investigative dermatology, 2013年04月, 査読あり, 招待無し

Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells
Y. C. Yang; H. C. Fu; B. L. Hsiao; G. Sobue; H. Adachi; F. J. Huang; Y. D. Hsuuw; K. T. Wei; C. Chang; K. E. Huang; H. Y. Kang
Cell Death and Disease, 2013年04月, 査読あり, 招待無し

Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration
Naohide Kondo; Masahisa Katsuno; Hiroaki Adachi; Makoto Minamiyama; Hideki Doi; Shinjiro Matsumoto; Yu Miyazaki; Madoka Iida; Genki Tohnai; Hideaki Nakatsuji; Shinsuke Ishigaki; Yusuke Fujioka; Hirohisa Watanabe; Fumiaki Tanaka; Akira Nakai; Gen Sobue
NATURE COMMUNICATIONS, 2013年01月, 査読あり, 招待無し

Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA)
Masahisa Katsuno; Fumiaki Tanaka; Hiroaki Adachi; Haruhiko Banno; Keisuke Suzuki; Hirohisa Watanabe; Gen Sobue
PROGRESS IN NEUROBIOLOGY, 2012年12月, 査読あり, 招待無し

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract
Makoto Minamiyama; Masahisa Katsuno; Hiroaki Adachi; Hideki Doi; Naohide Kondo; Madoka Iida; Shinsuke Ishigaki; Yusuke Fujioka; Shinjiro Matsumoto; Yu Miyazaki; Fumiaki Tanaka; Hiroki Kurihara; Gen Sobue
NATURE MEDICINE, 2012年10月, 査読あり, 招待無し

c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis
Ryu Katsumata; Shinsuke Ishigaki; Masahisa Katsuno; Kaori Kawai; Jun Sone; Zhe Huang; Hiroaki Adachi; Fumiaki Tanaka; Fumihiko Urano; Gen Sobue
PLOS ONE, 2012年09月, 査読あり, 招待無し

[109th Scientific Meeting of the Japanese Society of Internal Medicine: symposium: 2. Translational research and evidence-based medicine (EBM) in internal medicine in Japan, translational research; 1) Translational research on neurodegenerative diseases].
Katsuno M; Banno H; Suzuki K; Hashizume A; Adachi H; Tanaka F; Sobue G
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012年09月, 査読あり, 招待無し

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2
Yu Miyazaki; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Yue-Mei Jiang; Zhe Huang; Hideki Doi; Shinjiro Matsumoto; Naohide Kondo; Madoka Iida; Genki Tohnai; Fumiaki Tanaka; Shin-ichi Muramatsu; Gen Sobue
NATURE MEDICINE, 2012年07月, 査読あり, 招待無し

Molecular Pathophysiology and Disease-Modifying Therapies for Spinal and Bulbar Muscular Atrophy
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
ARCHIVES OF NEUROLOGY, 2012年04月, 査読あり, 招待無し

Disease-modifying therapy for spinal and bulbar muscular atrophy (SBMA)
Keisuke Suzuki; Haruhiko Banno; Masahisa Katsuno; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Brain and Nerve, 2012年03月, 査読あり, 招待無し

我が国の内科領域のトランスレーショナルリサーチとEBM トランスレーショナルリサーチ 神経変性疾患のトランスレーショナルリサーチ
勝野 雅央; 坂野 晴彦; 鈴木 啓介; 橋詰 淳; 足立 弘明; 田中 章景; 祖父江 元
日本内科学会雑誌, 2012年02月

Current status of treatment of spinal and bulbar muscular atrophy
Fumiaki Tanaka; Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Gen Sobue
Neural Plasticity, 2012年, 査読あり, 招待無し

[Anti-androgen therapy for spinal and bulbar muscular atrophy (SBMA)].
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Atsushi Hashizume; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Rinsho shinkeigaku = Clinical neurology, 2012年, 査読あり, 招待無し

Disease-modifying therapy for spinal and bulbar muscular atrophy (SBMA)
Suzuki, K.; Banno, H.; Katsuno, M.; Adachi, H.; Tanaka, F.; Sobue, G.
Brain and Nerve, 2012年, 査読あり, 招待無し

球脊髄性筋萎縮症における細胞周期異常
勝野 雅央; 足立 弘明; 南山 誠; 土井 英樹; 近藤 直英; 松本 慎二郎; 宮崎 雄; 坂野 晴彦; 鈴木 啓介; 田中 章景; 祖父江 元
臨床神経学, 2011年12月

[The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease].
Adachi H
Rinsho shinkeigaku = Clinical neurology, 2011年11月, 査読あり, 招待無し

神経変性をどう考えるか?病態理解にいたる最近の進歩 TGF-βシグナルからみた神経変性機序
勝野 雅央; 坂野 晴彦; 鈴木 啓介; 足立 弘明; 田中 章景; 祖父江 元
臨床神経学, 2011年11月

神経変性疾患の病態と治療(脊髄小脳変性症を含む) 神経変性疾患の分子標的治療
祖父江 元; 勝野 雅央; 坂野 晴彦; 足立 弘明; 田中 章景
日本医学会総会会誌, 2011年10月

Macroautophagy Is Regulated by the UPR-Mediator CHOP and Accentuates the Phenotype of SBMA Mice
Zhigang Yu; Adrienne M. Wang; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Zhenyu Yue; Diane M. Robins; Andrew P. Lieberman
PLOS GENETICS, 2011年10月, 査読あり, 招待無し

Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice
Tatsuya Hoshino; Naoya Murao; Takushi Namba; Masaya Takehara; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Takahide Matsushima; Toshiharu Suzuki; Tohru Mizushima
JOURNAL OF NEUROSCIENCE, 2011年04月, 査読あり, 招待無し

TGF-beta signaling in neurodegenerative diseases
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Clinical Neurology, 2011年, 査読あり, 招待無し

Spinal and Bulbar Muscular Atrophy
Sobue, G.; Adachi, H.; Katsuno, M.
Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition, 2011年, 査読あり, 招待無し

Transforming growth factor-β signaling in motor neuron diseases
Katsuno M; Adachi H; Banno H; Suzuki K; Tanaka F; Sobue G
Current Molecular Medicine, 2011年, 査読あり, 招待無し

The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease
Hiroaki Adachi
Clinical Neurology, 2011年, 査読あり, 招待無し

TGF-beta signaling in neurodegenerative diseases
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Clinical Neurology, 2011年, 査読あり, 招待無し

球脊髄性筋萎縮症(SBMA)における血管内皮細胞増殖因子(VEGF)の関与
川島 基; 勝野 雅央; 坂野 晴彦; 鈴木 啓介; 須賀 徳明; 橋詰 淳; 足立 弘明; 田中 章景; 祖父江 元
臨床神経学, 2010年12月

Clinicopathological features of acute autonomic and sensory neuropathy
Haruki Koike; Naoki Atsuta; Hiroaki Adachi; Masahiro Iijima; Masahisa Katsuno; Takeshi Yasuda; Yasuyo Fukada; Kenichi Yasui; Kenji Nakashima; Masahiro Horiuchi; Kazutaka Shiomi; Kazuhito Fukui; Shutaro Takashima; Yukari Morita; Kazumasa Kuniyoshi; Yasuhiro Hasegawa; Yasuhisa Toribe; Mitsugu Kajiura; Saoko Takeshita; Eiichiro Mukai; Gen Sobue
BRAIN, 2010年10月, 査読あり, 招待無し

Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy
Kaiguo Mo; Zak Razak; Pengcheng Rao; Zhigang Yu; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Andrew P. Lieberman; J. Timothy Westwood; D. Ashley Monks
PLOS ONE, 2010年09月, 査読あり, 招待無し

球脊髄性筋萎縮症(SBMA)におけるナトリウムチャンネルの発現異常(Expression pattern of sodium channels is dysregulated in spinal and bulbar musclar atrophy (SBMA))
勝野 雅央; 足立 弘明; 南山 誠; 土井 英樹; 近藤 直英; 松本 慎二郎; 坂野 晴彦; 鈴木 啓介; 田中 章景; 祖父江 元
神経化学, 2010年08月

Suppression of melanin production by expression of HSP70.
Tatsuya Hoshino; Minoru Matsuda; Yasuhiro Yamashita; Masaya Takehara; Masayo Fukuya; Kazutaka Mineda; Daisuke Maji; Hironobu Ihn; Hiroaki Adachi; Gen Sobue; Yoko Funasaka; Tohru Mizushima
The Journal of biological chemistry, 2010年04月, 査読あり, 招待無し

Disrupted Transforming Growth Factor-beta Signaling in Spinal and Bulbar Muscular Atrophy
Masahisa Katsuno; Hiroaki Adachi; Makoto Minamiyama; Masahiro Waza; Hideki Doi; Naohide Kondo; Hiroyuki Mizoguchi; Atsumi Nitta; Kiyofumi Yamada; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
JOURNAL OF NEUROSCIENCE, 2010年04月, 査読あり, 招待無し

Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70.
Minoru Matsuda; Tatsuya Hoshino; Yasuhiro Yamashita; Ken-ichiro Tanaka; Daisuke Maji; Keizo Sato; Hiroaki Adachi; Gen Sobue; Hironobu Ihn; Yoko Funasaka; Tohru Mizushima
The Journal of biological chemistry, 2010年02月, 査読あり, 招待無し

Dorfin Ameliorates Phenotypes in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
Jun Sone; Jun-ichi Niwa; Kaori Kawai; Shinsuke Ishigaki; Shin-ichi Yamada; Hiroaki Adachi; Masahisa Katsuno; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
JOURNAL OF NEUROSCIENCE RESEARCH, 2010年01月, 査読あり, 招待無し

Clinical Features and Molecular Mechanisms of Spinal and Bulbar Muscular Atrophy (SBMA)
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
DISEASES OF DNA REPAIR, 2010年, 査読あり, 招待無し

ポルグルタミン病におけるTGFβシグナル異常
勝野 雅央; 足立 弘明; 南山 誠; 和座 雅浩; 徳井 啓介; 土井 英樹; 坂野 晴彦; 鈴木 啓介; 竹内 優; 川島 基; 須賀 徳明; 祖父江 元
臨床神経学, 2009年12月

球脊髄性筋萎縮症におけるリュープロレリン酢酸塩の第2相試験
坂野 晴彦; 勝野 雅央; 鈴木 啓介; 竹内 優; 川島 基; 須賀 徳明; 高森 元子; 伊藤 瑞規; 中村 友彦; 松尾 幸司; 山田 新一; 沖 祐美子; 足立 弘明; 南山 誠; 和座 雅浩; 熱田 直樹; 渡邉 宏久; 藤本 保志; 田中 章景; 道勇 学; 祖父江 元
臨床神経学, 2009年12月

急性自律性感覚性ニューロパチーの臨床病理学的検討
小池 春樹; 熱田 直樹; 足立 弘明; 飯島 正博; 服部 直樹; 深田 育代; 安井 建一; 中島 健二; 堀内 正浩; 塩見 一剛; 福居 和人; 高嶋 修太郎; 森田 ゆかり; 国吉 和昌; 長谷川 康博; 鳥邊 泰久; 梶浦 貢; 武下 草生子; 祖父江 元
臨床神経学, 2009年12月, 査読あり, 招待無し

ポリグルタミン病への分子生物学的アプローチ 球脊髄性筋萎縮症に対する分子治療
勝野 雅央; 坂野 晴彦; 鈴木 啓介; 足立 弘明; 田中 章景; 祖父江 元
臨床神経学, 2009年11月

HSP70 Confers Protection against Indomethacin-Induced Lesions of the Small Intestine
Teita Asano; Ken-Ichiro Tanaka; Naoki Yamakawa; Hiroaki Adachi; Gen Sobue; Hidemi Goto; Koji Takeuchi; Tohru Mizushima
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2009年08月, 査読あり, 招待無し

TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases
Yohei Iguchi; Masahisa Katsuno; Jun-ichi Niwa; Shin-ichi Yamada; Jun Sone; Masahiro Waza; Hiroaki Adachi; Fumiaki Tanaka; Koh-ichi Nagata; Nariko Arimura; Takashi Watanabe; Kozo Kaibuchi; Gen Sobue
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009年08月, 査読あり, 招待無し

Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy
Isabella Palazzolo; Conor Stack; Lingling Kong; Antonio Musaro; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; J. Paul Taylor; Charlotte J. Sumner; Kenneth H. Fischbeck; Maria Pennuto
NEURON, 2009年08月, 査読あり, 招待無し

Molecular-targeted therapy for motor neuron disease
Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Yohei Iguchi; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Brain and Nerve, 2009年08月, 査読あり, 招待無し

【神経・筋疾患の分子標的治療】運動ニューロン疾患の分子標的治療
坂野 晴彦; 勝野 雅央; 鈴木 啓介; 井口 洋平; 足立 弘明; 田中 章景; 祖父江 元
BRAIN and NERVE: 神経研究の進歩, 2009年08月

Molecular-targeted therapy for motor neuron disease
Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Yohei Iguchi; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Brain and Nerve, 2009年08月, 査読あり, 招待無し

A Role for HSP70 in Protecting against Indomethacin-induced Gastric Lesions
Shintaro Suemasu; Ken-Ichiro Tanaka; Takushi Namba; Tomoaki Ishihara; Takashi Katsu; Mitsuaki Fujimoto; Hiroaki Adachi; Gen Sobue; Koji Takeuchi; Akira Nakai; Tohru Mizushima
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009年07月, 査読あり, 招待無し

【神経変性疾患研究の新機軸 その新たな研究戦略が謎を解く】運動ニューロン疾患の病因解析と治療法の開発
勝野 雅央; 坂野 晴彦; 鈴木 啓介; 足立 弘明; 田中 章景; 祖父江 元
細胞工学, 2009年04月

17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse
Keisuke Tokui; Hiroaki Adachi; Masahiro Waza; Masahisa Katsuno; Makoto Minamiyama; Hideki Doi; Keiji Tanaka; Jun Hamazaki; Shigeo Murata; Fumiaki Tanaka; Gen Sobue
HUMAN MOLECULAR GENETICS, 2009年03月, 査読あり, 招待無し

The case for cholesterol
Masahisa Katsuno; Hiroaki Adachi; Gen Sobue
NATURE MEDICINE, 2009年03月, 査読あり, 招待無し

Phase 2 Trial of Leuprorelin in Patients with Spinal and Bulbar Muscular Atrophy
Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Yu Takeuchi; Motoshi Kawashima; Noriaki Suga; Motoko Takamori; Mizuki Ito; Tomohiko Nakamura; Koji Matsuo; Shinichi Yamada; Yumiko Oki; Hiroaki Adachi; Makoto Minamiyama; Masahiro Waza; Naoki Atsuta; Hirohisa Watanabe; Yasushi Fujimoto; Tsutomu Nakashima; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
ANNALS OF NEUROLOGY, 2009年02月, 査読あり, 招待無し

Heat shock proteins in neurodegenerative diseases: Pathogenic roles and therapeutic implications
Hiroaki Adachi; Masahisa Katsuno; Masahiro Waza; Makoto Minamiyama; Fumiaki Tanaka; Gen Sobue
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2009年, 査読あり, 招待無し

Molecular-targeted therapies for spinal and bulbar muscular atrophy
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Clinical Neurology, 2009年, 査読あり, 招待無し

球脊髄性筋萎縮症の病態におけるVEGFの関与
川島 基; 勝野 雅央; 足立 弘明; 坂野 晴彦; 鈴木 啓介; 竹内 優; 祖父江 元
臨床神経学, 2008年12月

Molecular genetics and biomarkers of polyglutamine diseases
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Yu Takeuchi; Motoshi Kawashima; Fumiaki Tanaka; Hiroaki Adachi; Gen Sobue
CURRENT MOLECULAR MEDICINE, 2008年05月, 査読あり, 招待無し

球脊髄性筋萎縮症の筋病変
勝野 雅央; 足立 弘明; 南山 誠; 和座 雅浩; 徳井 啓介; 坂野 晴彦; 鈴木 啓介; 竹内 優; 田中 章景; 道勇 学; 祖父江 元
臨床神経学, 2007年12月

Therapeutic strategies for spinal and bulbar muscular atrophy (SBMA)
Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Yu Takeuchi; Makoto Minamiyama; Masahiro Waza; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
DRUGS OF THE FUTURE, 2007年10月, 査読あり, 招待無し

Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis
Ken-Ichiro Tanaka; Takushi Namba; Yasuhiro Arai; Mitsuaki Fujimoto; Hiroaki Adachi; Gen Sobue; Koji Takeuchi; Akira Nakai; Tohru Mizushima
JOURNAL OF BIOLOGICAL CHEMISTRY, 2007年08月, 査読あり, 招待無し

Gene expressions specifically detected in motor neurons (Dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to Pathologic markers in sporadic amyotrophic lateral sclerosis
Yue-Mei Jiang; Masahiko Yamamoto; Fumiaki Tanaka; Shinsuke Ishigaki; Masahisa Katsuno; Hiroaki Adachi; Jun-ichi Niwa; Manabu Doyu; Marl Yoshida; Yoshio Hashizume; Gen Sobue
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2007年07月, 査読あり, 招待無し

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model
Hiroaki Adachi; Masahiro Waza; Keisuke Tokui; Masahisa Katsuno; Makoto Minamiyama; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
JOURNAL OF NEUROSCIENCE, 2007年05月, 査読あり, 招待無し

早期の抗結核療法が著効したcranio-cervical tuberculosisの1例
土井 英樹; 渡邉 宏久; 伊藤 瑞規; 足立 弘明; 道勇 学; 祖父江 元
神経治療学, 2007年05月

Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy
H. Adachi; M. Waza; M. Katsuno; F. Tanaka; M. Doyu; G. Sobue
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2007年04月, 査読あり, 招待無し

ポリグルタミン病の病変部におけるHsp70発現低下 機序および病態への関与
勝野 雅央; 坂野 晴彦; 鈴木 啓介; 足立 弘明; 和座 雅浩; 南山 誠; 徳井 啓介; 田中 章景; 道勇 学; 祖父江 元
臨床神経学, 2006年12月

球脊髄性筋萎縮症に対する酢酸リュープロレリンのプラセボ対照ランダム化比較試験
坂野 晴彦; 勝野 雅央; 鈴木 啓介; 和座 雅浩; 山田 新一; 沖 祐美子; 高森 元子; 熱田 直樹; 伊藤 瑞規; 松尾 幸治; 南山 誠; 中村 友彦; 渡邉 宏久; 足立 弘明; 田中 章景; 道勇 学; 片山 直美; 藤本 保志; 中島 務; 祖父江 元
臨床神経学, 2006年12月

Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration
Masahisa Katsuno; Hiroaki Adachi; Makoto Minamiyama; Masahiro Waza; Keisuke Tokui; Haruhiko Banno; Keisuke Suzuki; Yu Onoda; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
JOURNAL OF NEUROSCIENCE, 2006年11月, 査読あり, 招待無し

Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein
Masahiro Waza; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
JOURNAL OF MOLECULAR MEDICINE-JMM, 2006年08月, 査読あり, 招待無し

Pathogenesis, animal models and therapeutics in Spinal and bulbar muscular atrophy (SBMA)
Masahisa Katsuno; Hiroaki Adachi; Masahiro Waza; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
EXPERIMENTAL NEUROLOGY, 2006年07月, 査読あり, 招待無し

【再生医学をめぐる最新の展開】神経変性疾患の治療開発 球脊髄性筋萎縮症(SBMA)を中心に
坂野 晴彦; 勝野 雅央; 小野田 優; 鈴木 啓介; 徳井 啓介; 和座 雅浩; 南山 誠; 足立 弘明; 田中 章景; 道勇 学; 祖父江 元
現代医学, 2006年07月

Classic polyarteritis nodosa presenting rare clinical manifestations in a patient with hemophilia A
T Matsushita; H Adachi; H Watanabe; Y Shimoyama; T Adachi; G Sobue; M Ito; T Kojima; H Saito; T Naoe
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2006年06月, 査読あり, 招待無し

Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin: A pathogenic marker
H Banno; H Adachi; M Katsuno; K Suzuki; N Atsuta; H Watanabe; F Tanaka; M Doyu; G Sobue
ANNALS OF NEUROLOGY, 2006年03月, 査読あり, 招待無し

Alleviating neurodegeneration by an anticancer agent - An Hsp90 inhibitor (17-AAG)
Masahiro Waza; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Fumiaki Tanaka; Gen Sobue
INTEGRATED MOLECULAR MEDICINE FOR NEURONAL AND NEOPLASTIC DISORDERS, 2006年, 査読あり, 招待無し

球脊髄性筋萎縮症におけるsurrogate markerの探索
道勇 学; 坂野 晴彦; 勝野 雅央; 鈴木 啓介; 足立 弘明; 和座 雅浩; 南山 誠; 熱田 直樹; 渡邉 宏久; 田中 章景; 祖父江 元
臨床神経学, 2005年12月

Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease
M Katsuno; C Sang; H Adachi; M Minamiyama; M Waza; F Tanaka; M Doyu; G Sobue
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005年11月, 査読あり, 招待無し

神経変性疾患の新規治療法開発の最前線 実験室から臨床へ 球脊髄性筋萎縮症のホルモン関連治療
祖父江 元; 勝野 雅央; 坂野 晴彦; 鈴木 啓介; 和座 雅浩; 南山 誠; 足立 弘明
神経治療学, 2005年11月

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration
M Waza; H Adachi; M Katsuno; M Minamiyama; C Sang; F Tanaka; A Inukai; M Doyu; G Sobue
NATURE MEDICINE, 2005年10月, 査読あり, 招待無し

球脊髄性筋萎縮症におけるsurrogate markerの探索
坂野 晴彦; 勝野 雅央; 足立 弘明; 和座 雅浩; 南山 誠; 熱田 直樹; 渡邉 宏久; 田中 章景; 道勇 学; 祖父江 元
神経治療学, 2005年05月

Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients
H Adachi; M Katsuno; M Minamiyama; M Waza; C Sang; Y Nakagomi; Y Kobayashi; F Tanaka; M Doyu; A Inukai; M Yoshida; Y Hashizume; G Sobue
BRAIN, 2005年03月, 査読あり, 招待無し

Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
YM Jiang; M Yamamoto; Y Kobayashi; T Yoshihara; YD Liang; S Terao; H Takeuchi; S Ishigaki; M Katsuno; H Adachi; J Niwa; F Tanaka; M Doyu; M Yoshida; Y Hashizume; G Sobue
ANNALS OF NEUROLOGY, 2005年02月, 査読あり, 招待無し

Treatment of spinal and bulbar muscular atrophy
Hiroaki Adachi; Masahisa Katsuno; Gen Sobue
Brain and Nerve, 2004年09月, 査読あり, 招待無し

Treatment of spinal and bulbar muscular atrophy
Hiroaki Adachi; Masahisa Katsuno; Gen Sobue
Brain and Nerve, 2004年09月, 査読あり, 招待無し

[Development of the treatment for bulbospinal muscular atrophy].
Katsuno M; Adachi H; Hanno H; Sobue G
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004年07月, 査読あり, 招待無し

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
M Minamiyama; M Katsuno; H Adachi; M Waza; C Sang; Y Kobayashi; F Tanaka; M Doyu; A Inukai; G Sobue
HUMAN MOLECULAR GENETICS, 2004年06月, 査読あり, 招待無し

Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives
M Katsuno; H Adachi; F Tanaka; G Sobue
JOURNAL OF MOLECULAR MEDICINE-JMM, 2004年05月, 査読あり, 招待無し

Sweet relief for Huntington disease
M Katsuno; H Adachi; G Sobue
NATURE MEDICINE, 2004年02月, 査読あり, 招待無し

Development of the treatment for bulbospinal muscular atrophy
Katsuno, M.; Adachi, H.; Hanno, H.; Sobue, G.
[Zasshi] Journal. Nihon Naika Gakkai, 2004年, 査読あり, 招待無し

Acute autonomic and sensory neuropathy(AASN)の臨床特徴 9症例の検討
熱田 直樹; 小池 春樹; 服部 直樹; 足立 弘明; 安田 武司; 安藤 哲朗; 向井 栄一郎; 後藤 洋二; 真野 和夫; 今村 一博; 祖父江 元
臨床神経学, 2003年12月

Hsp105 alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity
K Ishihara; N Yamagishi; Y Saito; H Adachi; Y Kobayashi; G Sobue; K Ohtsuka; T Hatayama
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003年07月, 査読あり, 招待無し

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy
M Katsuno; H Adachi; M Doyu; M Minamiyama; C Sang; Y Kobayashi; A Inukai; G Sobue
NATURE MEDICINE, 2003年06月, 査読あり, 招待無し

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein
H Adachi; M Katsuno; M Minamiyama; C Sang; G Pagoulatos; C Angelidis; M Kusakabe; A Yoshiki; Y Kobayashi; M Doyu; G Sobue
JOURNAL OF NEUROSCIENCE, 2003年03月, 査読あり, 招待無し

Transgenic mouse models of spinal and bulbar muscular atrophy (SBMA)
M Katsuno; H Adachi; A Inukai; G Sobue
CYTOGENETIC AND GENOME RESEARCH, 2003年, 査読あり, 招待無し

Chaperone-based therapeutic strategy for polyglutamine diseases
Kobayashi Y; Adachi H; Katsuno M; Sobue G
Japanese Journal of Clinical Chemistry, 2003年, 査読あり, 招待無し

c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line
C Sang; Y Kobayashi; J Du; M Katsumo; H Adachi; M Doyu; G Sobue
MOLECULAR BRAIN RESEARCH, 2002年12月, 査読あり, 招待無し

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
M Katsuno; H Adachi; A Kume; M Li; Y Nakagomi; H Niwa; C Sang; Y Kobayashi; M Doyu; G Sobue
NEURON, 2002年08月, 査読あり, 招待無し

Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death
H Adachi; A Kume; M Li; Y Nakagomi; H Niwa; J Do; C Sang; Y Kobayashi; M Doyu; G Sobue
HUMAN MOLECULAR GENETICS, 2001年05月, 査読あり, 招待無し

Understanding of polyglutamine diseases through transgenic mouse models
Adachi H; Sobue G
Brain and Nerve, 2001年, 査読あり, 招待無し

Understanding of polyglutamine diseases through transgenic mouse models
H. Adachi; G. Sobue
Brain and Nerve, 2001年, 査読あり, 招待無し

Direct gram staining of blood culture sample enabled the early diagnosis of brain abscess due to Listeria monocytogenes
Akemi Takano; Hiroaki Adachi; Masashi Mizuno; Kumiko Kawamura; Gen Sobue
Clinical Neurology, 1999年11月, 査読あり, 招待無し

[Acute sensory neuropathy]
Adachi H; Sobue G
Ryōikibetsu shōkōgun shirīzu, 1999年, 査読あり, 招待無し

A severe case of acute autonomic and sensory neuropathy
Adachi, H.; Mukai, E.; Okuda, S.; Kawada, T.
Clinical Neurology, 1998年, 査読あり, 招待無し

A case of Satoyoshi syndrome with symptoms resembling neuroleptic malignant syndrome
Adachi, H.; Riku, S.; Fujishiro, K.-I.; Kuru, S.
Clinical Neurology, 1998年, 査読あり, 招待無し

BIOLOGY TOPICS　神経変性疾患の予防に向けたオートファジー関連分子の病態への関与の解明
足立弘明
BIO Clinica, 2024年04月, 査読あり, 招待無し
筆頭著者

神経変性疾患の予防と治療におけるオートファジーの関与
足立弘明
BIO Clinica, 2024年12月, 査読なし, 招待有り
筆頭著者

神経変性疾患の予防に向けたオートファジー関連分子の病態への関与の解明
足立弘明
BIO Clinica, 2023年03月, 査読なし, 招待有り
筆頭著者

神経変性疾患の治療法開発に向けたオートファジー関連分子の病態への関与の解明
足立弘明
BIO Clinica, 2022年05月, 査読なし, 招待有り
筆頭著者

アカデミアから新規治療の実現へ―トランスレーショナルリサーチの現状 球脊髄性筋萎縮症の病態抑止治療―リュープロレリン酢酸塩
鈴木啓介, 坂野晴彦, 勝野雅央, 足立弘明, 田中章景, 祖父江元
Brain Nerve, 2012年03月, 査読なし, 招待無し

筋疾患・神経疾患のジェネティスク_x000D_ 球脊髄性筋萎縮症
足立弘明
Clinical Neuroscience, 2018年02月, 査読あり, 招待無し
筆頭著者

ヒト免疫グロブリンGは多発性硬化症患者由来の末梢血単核細胞のマトリックスメタロプロテイナーゼ-9産生を抑制する(Human immunoglobulin G suppresses the production of matrix metalloproteinase-9 in peripheral blood mononuclear cells of patients with multiple sclerosis)
Okada Kazumasa, Adachi Hiroaki
Clinical and Experimental Neuroimmunology, 2015年08月, 査読あり, 招待無し
ラスト(シニア)オーサー

Hippocampal sclerosis without visually detectable hippocampal MRI abnormalities: automated subfield volumetric analysis.
Masaki Hiromi, Watanabe Keita, Kakeda Shingo, Ide Satoru, Sugimoto Kohichiro, Ueda Issei, Hamamura Toshihiko, Hisanaga Sachi, Toyota Tomoko, Akamatsu Naoki, Shimajiri Shohei, Yamamoto Junkoh, Nishizawa Shigeru, Adachi Hiroaki, Korogi Yukunori
Japanese journal of radiology, 2020年11月, 査読あり, 招待無し

抗LGI1抗体陽性自己免疫性脳炎の1例
東盛 雄政, 橋本 智代, 長坂 昌平, 山本 淳考, 赤松 直樹, 岡田 和将, 足立 弘明
Journal of Japan Society of Neurological Emergencies & Critical Care, 2022年06月, 査読あり, 招待有り
ラスト(シニア)オーサー

神経変性疾患の治療法開発に向けたオートファジー関連分子の病態解明
足立弘明
Medical Science Digest, 2019年04月, 査読なし, 招待有り
筆頭著者

体幹ジストニアから発症したパーキンソン病の1例
安田 千春, 武井 嵩展, 魚住 武則, 豊田 知子, 由比 友顕, 足立 弘明
Rinsho shinkeigaku = Clinical neurology, 2016年09月, 査読あり, 招待無し
ラスト(シニア)オーサー

神経変性疾患の分子標的治療の開発
足立弘明
Tracer, 2013年03月, 査読なし, 招待無し

レーザースペックルフローグラフィーを用いた累積振動ばく露による振動工具取扱者の手指末梢循環の評価
吉武 英隆、道井 聡史, 白坂 泰樹, 菅野 良介, 安藤 肇, 野澤 弘樹, 長谷川 将之, 池上 和範, 大成 圭子, 足立 弘明, 大神 明
労働安全衛生研究, 2020年09月, 査読あり, 招待無し

神経変性疾患とオートファジーの関連について
足立弘明
地域ケアリング, 2022年03月, 査読なし, 招待有り
筆頭著者

疾患モデルと分子標的探索による治療薬開発 8.神経変性疾患モデルの運動機能とその解析
足立弘明, 祖父江元
実験医学, 2012年02月, 査読なし, 招待無し

職場不適応を背景とした難治性空気嚥下症症例に対して生物心理社会的観点からの多角的治療が奏効した1例
本間 洋州、高橋 昌稔、兒玉 直樹、岡田 和将、足立 弘明
心身医学, 2018年08月, 査読あり, 招待無し
ラスト(シニア)オーサー

うつ病の精査中に骨髄異形成症候群を指摘した1例
本間 洋州, 高橋 昌稔, 兒玉 直樹, 岡田 和将, 足立 弘明
心身医学, 2015年10月, 査読なし, 招待無し

神経変性疾患のトランスレーショナルリサーチ
勝野 雅央, 坂野 晴彦, 鈴木 啓介, 橋詰 淳, 足立 弘明, 田中 章景, 祖父江 元
日本内科学会雑誌, 2012年09月, 査読なし, 招待無し

我が国の内科領域のトランスレーショナルリサーチとEBM トランスレーショナルリサーチ 1)神経変性疾患のトランスレーショナルリサーチ
勝野雅央, 坂野晴彦, 鈴木啓介, 橋詰淳, 足立弘明, 田中章景, 祖父江元
日本内科学会雑誌, 2012年09月, 査読なし, 招待無し

【「職業性末梢神経障害」】振動工具の取り扱いによる末梢神経障害
大成圭子, 池上和範, 道井聡史, 白坂泰樹, 安藤肇, 大神 明, 足立弘明
末梢神経, 2020年06月, 査読あり, 招待無し
ラスト(シニア)オーサー

急性自律性感覚性ニューロパチーの臨床病理学的検討
小池 春樹, 熱田 直樹, 足立 弘明, 冨田 稔, 両角 佐織, 川頭 祐一, 飯島 正博, 服部 直樹, 安田 武司, 深田 育代, 安井 建一, 中島 健二, 堀内 正浩, 塩見 一剛, 福居 和人, 高嶋 修太郎, 森田 ゆかり, 国吉 和昌, 長谷川 康博, 鳥邉 泰久, 祖父江 元
末梢神経 = Peripheral nerve, 2008年12月, 査読なし, 招待無し

【職域での若年性認知症への対応】若年性認知症の病態と職場での気づきと対応
足立 弘明
産業医学ジャーナル, 2022年05月, 査読なし, 招待有り
筆頭著者

【中枢性自律神経障害-最近の話題-】 神経性食欲不振症
高橋 昌稔, 兒玉 直樹, 足立 弘明
神経内科, 2016年01月, 査読なし, 招待有り
ラスト(シニア)オーサー

病態に根ざしたALSの新規治療法開発 変異SOD1(G93A)マウスにおけるc‐Abl阻害剤の治療効果
祖父江元, 勝又竜, 石垣診祐, 勝野雅央, 河合香織, 曽根淳, 足立弘明, 田中章景
神経変性疾患に関する調査研究班分科班「病態に根ざしたALSの新規治療法開発」 平成24年度 研究報告書, 2013年, 査読なし, 招待無し

神経変性疾患の治療法開発に向けたオートファジー関連分子の病態への関与の解明
足立弘明
細胞, 2021年03月, 査読あり, 招待有り
筆頭著者

オートファジーと小児神経疾患 蛋白質分解システムの強化による球脊髄性筋萎縮症の病態の改善
足立 弘明
脳と発達, 2016年05月, 査読なし, 招待無し
筆頭著者

視神経脊髄炎スペクトル障害(NMO-SD)　NMO-SDの電気生理学的所見
大成圭子、岡田和将、足立弘明
脳神経内科, 2019年01月, 査読なし, 招待有り
ラスト(シニア)オーサー

栄養指導に活かす行動医学の視点　よりよい患者理解のために―行動医学からみた各疾患領域　神経疾患
高橋昌稔、兒玉直樹、本間洋州、足立弘明
臨床栄養, 2018年05月, 査読なし, 招待有り
ラスト(シニア)オーサー

球脊髄性筋萎縮症(SBMA)に対する抗アンドロゲン療法
勝野雅央, 坂野晴彦, 鈴木啓介, 橋詰淳, 足立弘明, 田中章景, 祖父江元
臨床神経学, 2012年, 査読なし, 招待無し

良性成人型家族性ミオクローヌスてんかんの臨床所見及び脳波所見の特徴
豊田知子, 足立弘明
臨床神経生理学, 2023年04月, 査読あり, 招待有り
ラスト(シニア)オーサー

「臨床に役立つ基礎薬理学の用語解説」 ニューロエンジニアリング
足立弘明
臨床精神薬理, 2023年11月, 査読なし, 招待有り
筆頭著者, 責任著者

【外来における神経疾患の診かた】 外来で遭遇することの多い神経症候　頭痛
足立弘明
臨牀と研究, 2015年06月, 査読あり, 招待無し

各種病態モデルと創薬研究 1.神経疾患 5)球脊髄性筋萎縮症(SBMA)モデルマウスを用いた抗アンドロゲン療法の開発
勝野雅央, 坂野晴彦, 鈴木啓介, 足立弘明, 田中章景, 祖父江元
遺伝子医学MOOK, 2012年07月, 査読なし, 招待無し

各種難病の最新治療情報　球脊髄性筋萎縮症
足立 弘明
難病と在宅ケア, 2020年11月, 査読なし, 招待有り
筆頭著者

Usefulness of olfactory bulb measurement in 3D-FIESTA in differentiating Parkinson’s disease from atypical parkinsonism
Ide S, Murakami Y, Futatsuya K, Anai K, Yoshimatsu Y, Fukumitsu S, Tsukamoto J, Hashimoto T, Adachi H, Kakeda S, Aoki T.
American journal of neuroradiology, 2024年08月, 査読あり, 招待無し

Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy.
Hijikata Yasuhiro, Katsuno Masahisa, Suzuki Keisuke, Hashizume Atsushi, Araki Amane, Yamada Shinichiro, Inagaki Tomonori, Iida Madoka, Noda Seiya, Nakanishi Hirotaka, Banno Haruhiko, Mano Tomoo, Hirakawa Akihiro, Adachi Hiroaki, Watanabe Hirohisa, Yamamoto Masahiko, Sobue Gen
Annals of clinical and translational neurology, 2016年07月, 査読あり, 招待無し

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky Daniel J, Abdelmohsen Kotb, Abe Akihisa, Abedin Md Joynal, Abeliovich Hagai, Acevedo Arozena Abraham, Adachi Hiroaki, Adams Christopher M, Adams Peter D, Adeli Khosrow, Adhihetty Peter J, Adler Sharon G, Agam Galila, Agarwal Rajesh, Aghi Manish K, Agnello Maria, Agostinis Patrizia, Aguilar Patricia V, Aguirre-Ghiso Julio, Airoldi Edoardo M, Ait-Si-Ali Slimane, Akematsu Takahiko, Akporiaye Emmanuel T, Al-Rubeai Mohamed, Albaiceta Guillermo M, Albanese Chris, Albani Diego, Albert Matthew L, Aldudo Jesus, Algül Hana, Alirezaei Mehrdad, Alloza Iraide, Almasan Alexandru, Almonte-Beceril Maylin, Alnemri Emad S, Alonso Covadonga, Altan-Bonnet Nihal, Altieri Dario C, Alvarez Silvia, Alvarez-Erviti Lydia, Alves Sandro, Amadoro Giuseppina, Amano Atsuo, Amantini Consuelo, Ambrosio Santiago, Amelio Ivano, Amer Amal O, Amessou Mohamed, Amon Angelika, An Zhenyi, Anania Frank A, Andersen Stig U, Andley Usha P, Andreadi Catherine K, Andrieu-Abadie Nathalie, Anel Alberto, Ann David K, Anoopku
Autophagy, 2016年01月, 査読あり, 招待無し

Eating Disorder Neuroimaging Initiative (EDNI): a multicentre prospective cohort study protocol for elucidating the neural effects of cognitive-behavioural therapy for eating disorders.
Hamatani Sayo, Hirano Yoshiyuki, Sugawara Ayako, Isobe Masanori, Kodama Naoki, Yoshihara Kazufumi, Moriguchi Yoshiya, Ando Tetsuya, Endo Yuka, Takahashi Jumpei, Nohara Nobuhiro, Takamura Tsunehiko, Hori Hiroaki, Noda Tomomi, Tose Keima, Watanabe Keita, Adachi Hiroaki, Gondo Motoharu, Takakura Shu, Fukudo Shin, Shimizu Eiji, Yoshiuchi Kazuhiro, Sato Yasuhiro, Sekiguchi Atsushi
BMJ open, 2021年01月, 査読あり, 招待無し

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration.
Ding Ying, Adachi Hiroaki, Katsuno Masahisa, Huang Zhe, Jiang Yue-Mei, Kondo Naohide, Iida Madoka, Tohnai Genki, Nakatsuji Hideaki, Funakoshi Hiroshi, Nakamura Toshikazu, Sobue Gen
Biochemical and biophysical research communications, 2015年12月, 査読あり, 招待無し

Complete sequencing of expanded SAMD12 repeats by long-read sequencing and Cas9-mediated enrichment
Takeshi Mizuguchi, Tomoko Toyota, Satoko Miyatake, Satomi Mitsuhashi, Hiroshi Doi, Yosuke Kudo, Hitaru Kishida, Noriko Hayashi, Rie S Tsuburaya, Masako Kinoshita, Tetsuhiro Fukuyama, Hiromi Fukuda, Eriko Koshimizu, Naomi Tsuchida, Yuri Uchiyama, Atsushi Fujita, Atsushi Takata, Noriko Miyake, Mitsuhiro Kato, Fumiaki Tanaka, Hiroaki Adachi, Naomichi Matsumoto
Brain, 2021年04月, 査読あり, 招待無し

Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation
Minakawa EN, Popiel HA, Tada M, Takahashi T, Yamane H, Saitoh Y, Takahashi Y, Ozawa D, Takeda A, Takeuchi T, Okamoto Y, Yamamoto K, Suzuki M, Fujita H, Ito C, Yagihara H, Saito Y, Watase K, Adachi H, Katsuno M, Mochizuki H, Shiraki K, Sobue G, Toda T, Wada K, Onodera O, Nagai Y.
Brain : a journal of neurology, 2020年06月, 査読あり, 招待無し

CSF 14-3-3β is associated with progressive cognitive decline in Alzheimer’s disease
Qiang Q, Skudder-Hill L, Toyota T, Wei W, Adachi H.
Brain Communications, 2023年11月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Hippocampal Sclerosis After Legionnaires' Disease: A Case Report.
Ikenouchi Atsuko, Ide Satoru, Hayasaki Gaku, Adachi Hiroaki, Yoshimura Reiji
Cureus, 2024年12月, 査読あり, 招待無し

DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes5
Kondo N, Tohnai G, Sahashi K, Iida M, Kataoka M, Nakatsuji H, Tsutsumi Y, Hashizume A, Adachi H, Koike H, Shinjo K, Kondo Y, Sobue G, Katsuno M
EMBO molecular medicine, 2019年04月, 査読あり, 招待無し

Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.
Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
Endocrinology, 2014年07月, 査読あり, 招待無し

Muscle atrophy in chronic inflammatory demyelinating polyneuropathy: a computed tomography assessment.
Ohyama K, Koike H, Katsuno M, Takahashi M, Hashimoto R, Kawagashira Y, Iijima M, Adachi H, Watanabe H, Sobue G
European journal of neurology : the official journal of the European Federation of Neurological Societies, 2014年07月, 査読あり, 招待無し

Zebra sign of precentral gyri in amyotrophic lateral sclerosis: A novel finding using phase difference enhanced (PADRE) imaging-initial results.
Kakeda Shingo, Yoneda Tetsuya, Ide Satoru, Miyata Mari, Hashimoto Tomoyo, Futatsuya Koichiro, Watanabe Keita, Ogasawara Atsushi, Moriya Junji, Sato Toru, Okada Kazumasa, Uozumi Takenori, Adachi Hiroaki, Korogi Yukunori
European radiology, 2016年11月, 査読あり, 招待無し

Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA.
Halievski Katherine, Henley Casey L, Domino Laurel, Poort Jessica E, Fu Martina, Katsuno Masahisa, Adachi Hiroaki, Sobue Gen, Breedlove S Marc, Jordan Cynthia L
Experimental neurology, 2015年07月, 査読あり, 招待無し

Tandem-genotypes: robust detection of tandem repeat expansions from long DNA reads
Mitsuhashi S, Frith MC, Mizuguchi T, Miyatake S, Toyota T, Adachi H, Oma Y, Kino Y, Mitsuhashi H, Matsumoto N
Genome biology, 2019年03月, 査読あり, 招待無し

Olfactory-cognitive index distinguishes involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of medial temporal areas, and global brain, as in Kihon Checklist frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease.
Iritani Osamu, Okuno Tazuo, Miwa Takaki, Makizako Hyuma, Okutani Fumino, Kashibayashi Tetsuo, Suzuki Kumiko, Hara Hideo, Mori Eri, Omoto Shusaku, Suzuki Hirokazu, Shibata Minori, Adachi Hiroaki, Kondo Kenji, Umeda-Kameyama Yumi, Kodera Kumie, Morimoto Shigeto
Geriatrics & gerontology international, 2021年03月, 査読あり, 招待無し

Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise.
Ninomiya Hiromasa, Ohgami Nobutaka, Oshino Reina, Kato Masashi, Ohgami Kyoko, Li Xiang, Shen Dandan, Iida Machiko, Yajima Ichiro, Angelidis Charalampos E, Adachi Hiroaki, Katsuno Masahisa, Sobue Gen, Kato Masashi
Hearing research, 2018年06月, 査読あり, 招待無し

Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death
Adachi H, Kume A, Li M, Nakagomi Y, Niwa H, Do J, Sang C, Kobayashi Y, Doyu M,Sobue G
Hum Mol Genet, 2001年, 査読あり, 招待無し

Pre-clinical symptoms of SBMA may not be androgen-dependent:Implications from two SBMA mouse models.
Xu Y, Halievski K, Katsuno M, Adachi H, Sobue G, Breedlove SM, Jordan CL
Human molecular genetics, 2018年07月, 査読あり, 招待無し

Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy.
Sahashi Kentaro, Katsuno Masahisa, Hung Gene, Adachi Hiroaki, Kondo Naohide, Nakatsuji Hideaki, Tohnai Genki, Iida Madoka, Bennett C Frank, Sobue Gen
Human molecular genetics, 2015年11月, 査読あり, 招待無し

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.
Iida Madoka, Katsuno Masahisa, Nakatsuji Hideaki, Adachi Hiroaki, Kondo Naohide, Miyazaki Yu, Tohnai Genki, Ikenaka Kensuke, Watanabe Hirohisa, Yamamoto Masahiko, Kishida Ken, Sobue Gen
Human molecular genetics, 2015年01月, 査読あり, 招待無し

Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy.
Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
Human molecular genetics, 2014年07月, 査読あり, 招待無し

Late-onset Myasthenia Gravis Accompanied by Amyotrophic Lateral Sclerosis with Antibodies against the Acetylcholine Receptor and Low-density Lipoprotein Receptor-related Protein 4
Ohnari K, Okada K, Higuchi O, Matsuo H, Adachi H
Internal medicine, 2018年10月, 査読あり, 招待無し
ラスト(シニア)オーサー

Cerebrotendinous Xanthomatosis with Nodular-hypertrophy of the Lumbosacral Roots.
Hashimoto Tomoyo, Sennari Yusuke, Okada Kazumasa, Adachi Hiroaki
Internal medicine (Tokyo, Japan), 2018年06月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Disease affects Bdnf expression in synaptic and extrasynaptic regions of skeletal muscle of three SBMA mouse models
Halievski K, Nath SR, Katsuno M, Adachi H, Sobue G, Breedlove M, Lieberman AP, Jordan CL
International journal of molecular sciences, 2019年03月, 査読あり, 招待無し

Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy
Hirunagi T, Nakatsuji H, Sahashi K, Yamamoto M, Iida M, Tohnai G, Kondo N, Yamada S, Murakami A, Noda S, Adachi H, Sobue G, Katsuno M.
Journal of Cachexia, Sarcopenia and Muscle, 2024年02月, 査読あり, 招待無し

Complete SAMD12 repeat expansion sequencing in a four-generation BAFME1 family with anticipation
Mizuguchi T, Toyota T, Koshimizu E, Koshimizu E, Kameyama S, Fukuda H, Tsuchida N, Uchiyama Y, Hamanaka K, Fujita A, Misawa K, Miyatake S, Adachi H, Matsumoto N.
Journal of Human Genetics, 2023年08月, 査読あり, 招待無し

Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation.
Huang Zhe, Adachi Hiroaki
Journal of UOEH, 2016年06月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy.
Oki K, Halievski K, Vicente L, Xu Y, Zeolla D, Poort J, Katsuno M, Adachi H, Sobue G, Wiseman RW, Breedlove SM, Jordan CL
Journal of applied physiology (Bethesda, Md. : 1985), 2015年04月, 査読あり, 招待無し

Unclassified subtype of Guillain-Barré syndrome is associated with quick recovery.
Ohnari Keiko, Okada Kazumasa, Mafune Kosuke, Kusunoki Susumu, Adachi Hiroaki
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021年09月, 査読あり, 招待無し
ラスト(シニア)オーサー

Coexisting infectious diseases on admission as a risk factor for mechanical ventilation in patients with Guillain-Barré syndrome.
Kobori Shinichiro, Kubo Tatsuhiko, Otani Makoto, Muramatsu Keiji, Fujino Yoshihisa, Adachi Hiroaki, Horiguchi Hiromasa, Fushimi Kiyohide, Matsuda Shinya
Journal of epidemiology, 2017年03月, 指定なし, 指定なし

Detecting a long insertion variant in SAMD12 by SMRT sequencing: implications of long-read whole-genome sequencing for repeat expansion diseases
Mizuguchi T, Toyota T, Adachi H, Miyake N, Matsumoto N, Miyatake S
Journal of human genetics, 2019年03月, 査読あり, 招待無し

Facial nerve atrophy in patients with amyotrophic lateral sclerosis: Evaluation with fast imaging employing steady-state acquisition (FIESTA).
Miyata Mari, Kakeda Shingo, Hashimoto Tomoyo, Ide Satoru, Okada Kazumasa, Adachi Hiroaki, Korogi Yukunori
Journal of magnetic resonance imaging : JMRI, 2020年03月, 査読あり, 招待無し

Dramatic improvement in refractory myasthenia gravis with eculizumab treatment: a case report.
Ohnari K, Hashimoto T, Iwanaka Y, Ohnari K, Adachi Hi, Okada K.
Journal of neurology, 2024年05月, 査読あり, 招待無し

Multicenter, randomized, double-blind, placebo-controlled phase 3 study of mogamulizumab with open-label extension study in a minimum number of patients with human T-cell leukemia virus type-1-associated myelopathy.
Sato T, Nagai M, Watanabe O, Misu T, Takenouchi N, Ohkubo R, Ishihara S, Tsuboi Y, Katsuno M, Nakagawa M, Matsushita T, Aso Y, Matsuura E, Tokashiki T, Mukaino A, Adachi H, Nakanishi K, Yamaguchi Y, Yamaguchi S, Yamano Y.
Journal of neurology, 2024年06月, 査読あり, 招待無し

Complete nanopore repeat sequencing of SCA27B (GAA-FGF14 ataxia) in Japanese.
Miyatake S, Doi H, Yaguchi H, Koshimizu E, Kihara N, Matsubara T, Mori Y, Kunieda K, Shimizu Y, Toyota T, Shirai S, Matsushima M, Okubo M, Wada T, Kunii M, Johkura K, Miyamoto R, Osaki Y, Miyama T, Satoh M, Fujita A, Uchiyama Y, Tsuchida N, Misawa K, Hamanaka K, Hamanoue H, Mizuguchi T, Morino H, Izumi Y, Shimohata T, Yoshida K, Adachi H, Tanaka F, Yabe I, Matsumoto N.
Journal of neurology, neurosurgery, and psychiatry, 2024年05月, 査読あり, 招待無し

Defects in neuromuscular transmission may underlie motor dysfunction in SBMA.
Xu Y, Halievski K, Henley C, Atchison W, Katsuno M, Adachi H, Sobue G, Breedlove S, Jordan CL
The Journal of neuroscience, 2016年05月, 査読あり, 招待無し

Evaluation of hand-arm vibration syndrome owing to nerve conduction study and cumulative exposure index -A 2.5-year cohort study.
Ikegami K, Ohnari K, Shirasaka T, Michii S, Yoshitake H, Sugano R, Nozawa H, Hasegawa M, Ando H, Ogami A, Adachi H.
Journal of occupational and environmental medicine, 2024年08月, 査読あり, 招待無し
ラスト(シニア)オーサー

Muscle BDNF improves synaptic and contractile muscle strength in Kennedy's disease mice in a muscle-type specific manner
Halievski K, Xu Y, Haddad YW, Tang YP, Yamada S, Katsuno M, Adachi H, Sobue G, Breedlove SM, Jordan CL.
The Journal of physiology, 2020年04月, 査読あり, 招待無し

CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer’s disease
Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H.
The Journal of the Neurological Sciences, 2024年02月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Usefulness of the Gold Coast criteria in diagnosing fast-progressing amyotrophic lateral sclerosis.
Ohnari Keiko, Mafune Kosuke, Adachi Hiroaki
Journal of the neurological sciences, 2025年04月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Signal intensity of cerebral gyri in corticobasal syndrome on phase difference enhanced magnetic resonance images: Comparison of progressive supranuclear palsy and Parkinson's disease.
Miyata Mari, Kakeda Shingo, Yoneda Tetsuya, Ide Satoru, Okada Kazumasa, Adachi Hiroaki, Korogi Yukunori
Journal of the neurological sciences, 2020年12月, 査読あり, 招待無し

The facial nerve atrophy with spinal and bulbar muscular atrophy patients (SBMA): Three case reports with 3D fast imaging employing steady-state acquisition (FIESTA).
Miyata Mari, Kakeda Shingo, Hashimoto Tomoyo, Korogi Yukunori, Adachi Hiroaki
Journal of the neurological sciences, 2019年11月, 査読あり, 招待無し
ラスト(シニア)オーサー

Detection of dentate nuclei abnormality in a patient with dentatorubral-pallidoluysian atrophy using the quantitative susceptibility mapping.
Ide Satoru, Kakeda Shingo, Adachi Hiroaki, Miyata Mari, Iwanaka Yukio, Okada Kazumasa, Korogi Yukunori
Journal of the neurological sciences, 2019年08月, 査読あり, 招待無し

Evoked potentials are useful for diagnosis of neuromyelitis optica spectrum disorder.
Ohnari Keiko, Okada Kazumasa, Takahashi Toshiyuki, Mafune Kosuke, Adachi Hiroaki
Journal of the neurological sciences, 2016年05月, 査読あり, 招待無し
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Axonal loss influences the response to rituximab treatment in neuropathy associated with IgM monoclonal gammopathy with anti-myelin-associated glycoprotein antibody.
Kawagashira Yuichi, Koike Haruki, Ohyama Ken, Hashimoto Rina, Iijima Masahiro, Adachi Hiroaki, Katsuno Masahisa, Chapman Miles, Lunn Michael, Sobue Gen
Journal of the neurological sciences, 2015年01月, 査読あり, 招待無し

Juxtacortical Lesions in Multiple Sclerosis: Assessment of Gray Matter Involvement Using Phase Difference-enhanced Imaging (PADRE).
Futatsuya Koichiro, Kakeda Shingo, Yoneda Tetsuya, Ueda Issei, Watanabe Keita, Moriya Junji, Murakami Yu, Ide Satoru, Ogasawara Atsushi, Ohnari Norihiro, Okada Kazumasa, Adachi Hiroaki, Korogi Yukunori
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2016年10月, 査読あり, 招待無し

Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model.
Mitsui Shun, Otomo Asako, Nozaki Masahisa, Ono Suzuka, Sato Kai, Shirakawa Ryohei, Adachi Hiroaki, Aoki Masashi, Sobue Gen, Shang Hui-Fang, Hadano Shinji
Molecular brain, 2018年05月, 査読あり, 招待無し

Systematic reduction of gray matter volume in anorexia nervosa, but relative enlargement with clinical symptoms in the prefrontal and posterior insular cortices: a multicenter neuroimaging study.
Tose K, Takamura T, Isobe M, Hirano Y, Sato Y,Kodama N, Yoshihara K, Maikusa N, Moriguchi Y, Noda T, Mishima R, Kawabata M, Noma S, Takakura S, Gondo M, Kakeda S, Takahashi M,Ide S, Adachi H, Hamatani S, Kamashita R, Sudo Y, Matsumoto K, Nakazato M, Numata N, Hamamoto Y, Shoji T, Muratsubaki T, Sugiura M, Murai T, Fukudo S, Sekiguchi A.
Molecular psychiatry, 2024年04月, 査読あり, 招待無し

Rapid and comprehensive diagnostic method for repeat expansion diseases using nanopore sequencing.
Miyatake Satoko, Koshimizu Eriko, Fujita Atsushi, Doi Hiroshi, Okubo Masaki, Wada Taishi, Hamanaka Kohei, Ueda Naohisa, Kishida Hitaru, Minase Gaku, Matsuno Atsuhiro, Kodaira Minori, Ogata Katsuhisa, Kato Rumiko, Sugiyama Atsuhiko, Sasaki Ayako, Miyama Takabumi, Satoh Mai, Uchiyama Yuri, Tsuchida Naomi, Hamanoue Haruka, Misawa Kazuharu, Hayasaka Kiyoshi, Sekijima Yoshiki, Adachi Hiroaki, Yoshida Kunihiro, Tanaka Fumiaki, Mizuguchi Takeshi, Matsumoto Naomichi
NPJ genomic medicine, 2022年10月, 査読あり, 招待無し

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy.
Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, Adachi H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G, Katsuno M.
Nature Communications, 2019年09月, 査読あり, 招待無し

CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer's disease.
Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H.
Neurobiology of Aging, 2025年06月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Myoclonia continua in primary CNS natural killer/T-cell lymphoma, nasal type.
Toyota Tomoko, Sennari Yusuke, Okada Kazumasa, Kawahara Ai, Tsukada Junichi, Shimajiri Shohei, Adachi Hiroaki
Neurology, 2017年01月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Interictal epileptiform discharges in new-onset epilepsy among older adults
Toyota Tomoko, Akamatsu Naoki, Tanaka Akihiro, Yamano Mitsuhiko, Fujino Yoshihisa, Tsuji Sadatoshi, Adachi Hiroaki
Neurology and Clinical Neuroscience, 2016年01月, 査読あり, 招待無し
ラスト(シニア)オーサー

Neuronal intranuclear inclusion disease manifesting with new-onset epilepsy in the elderly
Toyota Tomoko, Huang Zhe, Nohara Souhei, Okada Kazumasa, Kakeda Shingo, Korogi Yukunori, Nakayama Toshiyuki, Sone Jun, Sobue Gen, Adachi Hiroaki
Neurology and Clinical Neuroscience, 2015年11月, 査読あり, 招待無し
ラスト(シニア)オーサー

Paraneoplastic neuromyelitis optica spectrum disorder manifesting as intractable nausea and acute cerebellar ataxia associated with lung adenocarcinoma
Kobata Masako, Okada Kazumasa, Hashimoto Tomoyo, Matsuyama Atsuji, Uchibori Ayumi, Takahashi Toshiyuki, Adachi Hiroaki
Neurology and Clinical Neuroscience, 2015年11月, 査読あり, 招待無し
ラスト(シニア)オーサー

Superior cerebellar peduncle atrophy of progressive supranuclear palsy on phase difference enhanced imaging: a comparison with Parkinson's disease.
Miyata Mari, Kakeda Shingo, Yoneda Tetsuya, Ide Satoru, Okada Kazumasa, Adachi Hiroaki, Korogi Yukunori
Neuroradiology, 2023年01月, 査読あり, 招待無し

Potential usefulness of signal intensity of cerebral gyri on quantitative susceptibility mapping for discriminating corticobasal degeneration from progressive supranuclear palsy and Parkinson's disease.
Miyata Mari, Kakeda Shingo, Toyoshima Yasuko, Ide Satoru, Okada Kazumasa, Adachi Hiroaki, Wang Yi, Korogi Yukunori
Neuroradiology, 2019年11月, 査読あり, 招待無し

BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
Ding Ying, Adachi Hiroaki, Katsuno Masahisa, Sahashi Kentaro, Kondo Naohide, Iida Madoka, Tohnai Genki, Nakatsuji Hideaki, Sobue Gen
Neuroscience, 2016年07月, 査読あり, 招待無し

Electrophysiological Findings in Neuromyelitis Optica Spectrum Disorder
Keiko Ohnari, Hiroaki Adachi
Online Journal of Neurology and Brain Disorders, 2021年01月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Fasciculation potentials are related to the prognosis of amyotrophic lateral sclerosis.
Ohnari K, Mafune K, Adachi H.
PLOS ONE, 2024年11月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Neuropsychiatric systemic lupus erythematosus detected using extravascular spillage signal on dynamic magnetic resonance imaging (Ktrans).
Fujita Yuya, Iwata Shigeru, Nakano Kazuhisa, Adachi Hiroaki, Tanaka Yoshiya
Rheumatology (Oxford, England), 2022年04月, 査読あり, 招待無し

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.
Kino Yoshihiro, Washizu Chika, Kurosawa Masaru, Yamada Mizuki, Doi Hiroshi, Takumi Toru, Adachi Hiroaki, Katsuno Masahisa, Sobue Gen, Hicks Geoffrey G, Hattori Nobutaka, Shimogori Tomomi, Nukina Nobuyuki
Scientific reports, 2016年10月, 査読あり, 招待無し

A multicenter cross-sectional study to elucidate altered resting-state functional connectivity of the insular cortex in anorexia nervosa, segmented by functional localization.
Sudo Yusuke, Kamashita Rio, Takamura Tsunehiko, Hamatani Sayo, Numata Noriko, Matsumoto Koji, Sato Yasuhiro, Hamamoto Yumi, Shoji Tomotaka, Muratsubaki Tomohiko, Sugiura Motoaki, Fukudo Shin, Kawabata Michiko, Sunada Momo, Noda Tomomi, Tose Keima, Isobe Masanori, Kodama Naoki, Kakeda Shingo, Takahashi Masatoshi, Adachi Hiroaki, Takakura Shu, Gondo Motoharu, Yoshihara Kazufumi, Moriguchi Yoshiya, Shimizu Eiji, Sekiguchi Atsushi, Hirano Yoshiyuki
Scientific reports, 2025年05月, 査読あり, 招待無し

Optic radiation atrophy in Lewy body disease with visual hallucination on phase difference enhanced magnetic resonance images.
Miyata Mari, Kakeda Shingo, Yoneda Tetsuya, Ide Satoru, Okada Kazumasa, Adachi Hiroaki, Korogi Yukunori
Scientific reports, 2022年11月, 査読あり, 招待無し

CSF GAP-43 as a biomarker of synaptic dysfunction is associated with tau pathology in Alzheimer's disease.
Qiang Qiang, Skudder-Hill Loren, Toyota Tomoko, Wei Wenshi, Adachi Hiroaki
Scientific reports, 2022年10月, 査読あり, 招待無し
ラスト(シニア)オーサー, 責任著者

Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy.
Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G
Annals of neurology, 2009年02月, 査読あり, 招待無し

Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin: a pathogenic marker.
Banno H, Adachi H, Katsuno M, Suzuki K, Atsuta N, Watanabe H, Tanaka F, Doyu M, Sobue G
Annals of neurology, 2006年03月, 査読あり, 招待無し

Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis.
Jiang YM, Yamamoto M, Kobayashi Y, Yoshihara T, Liang Y, Terao S, Takeuchi H, Ishigaki S, Katsuno M, Adachi H, Niwa J, Tanaka F, Doyu M, Yoshida M, Hashizume Y, Sobue G
Annals of neurology, 2005年02月, 査読あり, 招待無し

Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
Waza M, Adachi H, Katsuno M, Minamiyama M, Tanaka F, Sobue G
Annals of the New York Academy of Sciences, 2006年11月, 査読あり, 招待無し

Molecular pathophysiology and disease-modifying therapies for spinal and bulbar muscular atrophy.
Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
Archives of neurology, 2012年04月, 査読あり, 招待無し

Clinicopathological features of neuropathy associated with lymphoma.
Tomita M, Koike H, Kawagashira Y, Iijima M, Adachi H, Taguchi J, Abe T, Sako K, Tsuji Y, Nakagawa M, Kanda F, Takeda F, Sugawara M, Toyoshima I, Asano N, Sobue G
Brain : a journal of neurology, 2013年08月, 査読あり, 招待無し

[Disease-modifying therapy for spinal and bulbar muscular atrophy (SBMA)].
Suzuki K, Banno H, Katsuno M, Adachi H, Tanaka F, Sobue G
Brain and nerve = Shinkei kenkyu no shinpo, 2012年03月, 査読あり, 招待無し

[Molecular-targeted therapy for motor neuron disease]
Banno H, Katsuno M, Suzuki K, Iguchi Y, Adachi H, Tanaka F, Sobue G
Brain and nerve = Shinkei kenkyu no shinpo, 2009年08月, 査読あり, 招待無し

c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line.
Sang C, Kobayashi Y, Du J, Katsumo M, Adachi H, Doyu M, Sobue G
Brain research. Molecular brain research, 2002年12月, 査読あり, 招待無し

Molecular genetics and biomarkers of polyglutamine diseases.
Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Tanaka F, Adachi H, Sobue G
Current molecular medicine, 2008年05月, 査読あり, 招待無し

Pathogenesis, animal models and therapeutics in spinal and bulbar muscular atrophy (SBMA).
Katsuno M, Adachi H, Waza M, Banno H, Suzuki K, Tanaka F, Doyu M, Sobue G
Experimental neurology, 2006年07月, 査読あり, 招待無し

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy.
Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP
Human molecular genetics, 2014年03月, 査読あり, 招待無し

17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.
Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G
Human molecular genetics, 2009年03月, 査読あり, 招待無し

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.
Minamiyama M, Katsuno M, Adachi H, Waza M, Sang C, Kobayashi Y, Tanaka F, Doyu M, Inukai A, Sobue G
Human molecular genetics, 2004年06月, 査読あり, 招待無し

Classic polyarteritis nodosa presenting rare clinical manifestations in a patient with hemophilia A.
Matsushita T, Adachi H, Watanabe H, Shimoyama Y, Adachi T, Sobue G, Ito M, Kojima T, Saito H, Naoe T
International journal of hematology, 2006年06月, 査読あり, 招待無し

Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications.
Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2009年12月, 査読あり, 招待無し

Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70.
Matsuda M, Hoshino T, Yamashita Y, Tanaka K, Maji D, Sato K, Adachi H, Sobue G, Ihn H, Funasaka Y, Mizushima T
The Journal of biological chemistry, 2010年02月, 査読あり, 招待無し

Suppression of melanin production by expression of HSP70.
Hoshino T, Matsuda M, Yamashita Y, Takehara M, Fukuya M, Mineda K, Maji D, Ihn H, Adachi H, Sobue G, Funasaka Y, Mizushima T
The Journal of biological chemistry, 2010年04月, 査読あり, 招待無し

TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases.
Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G
The Journal of biological chemistry, 2009年08月, 査読あり, 招待無し

A role for HSP70 in protecting against indomethacin-induced gastric lesions.
Suemasu S, Tanaka K, Namba T, Ishihara T, Katsu T, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T
The Journal of biological chemistry, 2009年07月, 査読あり, 招待無し

Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis.
Tanaka K, Namba T, Arai Y, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T
The Journal of biological chemistry, 2007年08月, 査読あり, 招待無し

Hsp105alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity.
Ishihara K, Yamagishi N, Saito Y, Adachi H, Kobayashi Y, Sobue G, Ohtsuka K, Hatayama T
The Journal of biological chemistry, 2003年07月, 査読あり, 招待無し

Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice.
Matsuda M, Hoshino T, Yamakawa N, Tahara K, Adachi H, Sobue G, Maji D, Ihn H, Mizushima T
The Journal of investigative dermatology, 2013年04月, 査読あり, 招待無し

Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein.
Waza M, Adachi H, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G
Journal of molecular medicine (Berlin, Germany), 2006年08月, 査読あり, 招待無し

Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives.
Katsuno M, Adachi H, Tanaka F, Sobue G
Journal of molecular medicine (Berlin, Germany), 2004年05月, 査読あり, 招待無し

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.
Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G
Journal of neurochemistry, 2013年07月, 査読あり, 招待無し

Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis.
Jiang YM, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizume Y, Sobue G
Journal of neuropathology and experimentalneurology, 2007年07月, 査読あり, 招待無し

p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.
Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Qiang Q, Tanaka F, Yanagawa T, Warabi E, Ishii T, Sobue G
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013年05月, 査読あり, 招待無し

Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.
Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010年04月, 査読あり, 招待無し

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.
Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007年05月, 査読あり, 招待無し

Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration.
Katsuno M, Adachi H, Minamiyama M, Waza M, Tokui K, Banno H, Suzuki K, Onoda Y, Tanaka F, Doyu M, Sobue G
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006年11月, 査読あり, 招待無し

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein.
Adachi H, Katsuno M, Minamiyama M, Sang C, Pagoulatos G, Angelidis C, Kusakabe M, Yoshiki A, Kobayashi Y, Doyu M, Sobue G
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003年03月, 査読あり, 招待無し

Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.
Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G
Journal of neuroscience research, 2010年01月, 査読あり, 招待無し

HSP70 confers protection against indomethacin-induced lesions of the small intestine.
Asano T, Tanaka K, Yamakawa N, Adachi H, Sobue G, Goto H, Takeuchi K, Mizushima T
The Journal of pharmacology and experimental therapeutics, 2009年08月, 査読あり, 招待無し

Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm.
Tanaka S, Banno H, Katsuno M, Suzuki K, Suga N, Hashizume A, Mano T, Araki A, Watanabe H, Adachi H, Tatsumi H, Yamamoto M, Sobue G
Journal of the neurological sciences, 2014年02月, 査読あり, 招待無し

Cortical and subcortical brain atrophy in Parkinson's disease with visual hallucination.
Watanabe H, Senda J, Kato S, Ito M, Atsuta N, Hara K, Tsuboi T, Katsuno M, Nakamura T, Hirayama M, Adachi H, Naganawa S, Sobue G
Movement disorders : official journal of the Movement Disorder Society, 2013年10月, 査読あり, 招待無し

Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration.
Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G
Nature communications, 2013年, 査読あり, 招待無し

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.
Katsuno M, Adachi H, Doyu M, Minamiyama M, Sang C, Kobayashi Y, Inukai A, Sobue G
Nature medicine, 2003年06月, 査読あり, 招待無し

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract.
Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
Nature medicine, 2012年10月, 査読あり, 招待無し

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2.
Miyazaki Y, Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G
Nature medicine, 2012年07月, 査読あり, 招待無し

Getting a handle on Huntington's disease: the case for cholesterol.
Katsuno M, Adachi H, Sobue G
Nature medicine, 2009年03月, 査読あり, 招待無し

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.
Waza M, Adachi H, Katsuno M, Minamiyama M, Sang C, Tanaka F, Inukai A, Doyu M, Sobue G
Nature medicine, 2005年10月, 査読あり, 招待無し

Sweet relief for Huntington disease.
Katsuno M, Adachi H, Sobue G
Nature medicine, 2004年02月, 査読あり, 招待無し

Current status of treatment of spinal and bulbar muscular atrophy.
Tanaka F, Katsuno M, Banno H, Suzuki K, Adachi H, Sobue G
Neural plasticity, 2012年, 査読あり, 招待無し

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.
Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M
Neuron, 2009年08月, 査読あり, 招待無し

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.
Katsuno M, Adachi H, Kume A, Li M, Nakagomi Y, Niwa H, Sang C, Kobayashi Y, Doyu M, Sobue G
Neuron, 2002年08月, 査読あり, 招待無し

[Development of the treatment for bulbospinal muscular atrophy]
Katsuno M, Adachi H, Hanno H, Sobue G
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004年07月, 査読あり, 招待無し

[109th Scientific Meeting of the Japanese Society of Internal Medicine: symposium: 2. Translational research and evidence-based medicine (EBM) in internal medicine in Japan, translational research; 1) Translational research on neurodegenerative diseases].
Katsuno M, Banno H, Suzuki K, Hashizume A, Adachi H, Tanaka F, Sobue G
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012年09月, 査読あり, 招待無し

[Treatment of spinal and bulbar muscular atrophy]
Adachi H, Katsuno M, Sobue G
No to shinkei = Brain and nerve, 2004年09月, 査読あり, 招待無し

Potential of a new MRI for visualizing cerebellar involvement in progressive supranuclear palsy.
Hara K, Watanabe H, Ito M, Tsuboi T, Watanabe H, Nakamura R, Senda J, Atsuta N, Adachi H, Aiba I, Naganawa S, Sobue G
Parkinsonism&related disorders, 2014年02月, 査読あり, 招待無し

RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-43.
Takagi S, Iguchi Y, Katsuno M, Ishigaki S, Ikenaka K, Fujioka Y, Honda D, Niwa J, Tanaka F, Watanabe H, Adachi H, Sobue G
PloS one, 2013年, 査読あり, 招待無し

c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis.
Katsumata R, Ishigaki S, Katsuno M, Kawai K, Sone J, Huang Z, Adachi H, Tanaka F, Urano F, Sobue G
PloS one, 2012年, 査読あり, 招待無し

Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease.
Katsuno M, Sang C, Adachi H, Minamiyama M, Waza M, Tanaka F, Doyu M, Sobue G
Proceedings of the National Academy of Sciences of the United States of America, 2005年11月, 査読あり, 招待無し

Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA).
Katsuno M, Tanaka F, Adachi H, Banno H, Suzuki K, Watanabe H, Sobue G
Progress in neurobiology, 2012年12月, 査読あり, 招待無し

PATIENT WITH PARKINSON'S DISEASE AND DEPRESSIVE SYMPTOMS ASSOCIATED WITH IMPULSE CONTROL DISORDER.
Migita Kanae, Okamoto Naomichi, Ikenouchi Atsuko, Kijima Reoto, Hashimoto Tomoyo, Adachi Hiroaki, Yoshimura Reiji
Psychiatria Danubina, 2024年05月, 査読あり, 招待無し

[Anti-androgen therapy for spinal and bulbar muscular atrophy (SBMA)].
Katsuno M, Banno H, Suzuki K, Hashizume A, Adachi H, Tanaka F, Sobue G
Rinsho shinkeigaku = Clinical neurology, 2012年, 査読あり, 招待無し

[TGF-beta signaling in neurodegenerative diseases].
Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
Rinsho shinkeigaku = Clinical neurology, 2011年11月, 査読あり, 招待無し

[The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease].
Adachi H
Rinsho shinkeigaku = Clinical neurology, 2011年11月, 査読あり, 招待無し

[Molecular-targeted therapies for spinal and bulbar muscular atrophy]
Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
Rinsho shinkeigaku = Clinical neurology, 2009年11月, 査読あり, 招待無し

病因タンパク質を標的としたHsp90阻害剤による神経変性疾患治療 (特集 神経変性の分子機構と治療戦略)
和座雅浩, 足立弘明, 勝野雅央
メディカルバイオ, 2008年05月, 査読なし, 招待無し

球脊髄性筋萎縮症に対する分子標的治療薬の開発--既存低分子化合物の臨床応用 (あゆみ トリプレットリピート病UPDATE)
和座雅浩, 足立弘明, 勝野雅央
医学のあゆみ, 2006年10月, 査読なし, 招待無し

アンドロゲン受容体を標的とした球脊髄性筋萎縮症の治療法開発 (第5土曜特集 分子標的薬) -- (神経)
足立弘明, 勝野雅央, 祖父江元
医学のあゆみ, 2004年01月, 査読なし, 招待無し

Guillain-Barre症候群に対する免疫吸着療法
足立弘明, 久留聡, 藤城健一郎, 陸重雄, 天野泉
日本アフェレシス学会雑誌, 1995年05月, 査読なし, 招待無し

球脊髄性筋萎縮症の治療法開発
勝野雅央, 足立弘明, 坂野晴彦, 祖父江元
日本内科学会雑誌, 2004年07月, 査読なし, 招待無し

球脊髄性筋萎縮症 (特集 第40回 脳のシンポジウム) -- (動物モデルからみた神経変性の病態と治療開発)
勝野雅央, 足立弘明, 祖父江元
神経研究の進歩, 2005年12月, 査読なし, 招待無し

球脊髄性筋萎縮症の動物モデル (特集 ポリグルタミン病の病態機序)
勝野雅央, 足立弘明, 祖父江元
神経研究の進歩, 2002年10月, 査読なし, 招待無し

ポリグルタミン病:球脊髄性筋萎縮症における細胞障害機序 (特集 第36回脳のシンポジウム) -- (トリプレットリピートの生物学的意義)
足立弘明, 祖父江元
神経研究の進歩, 2001年12月, 査読なし, 招待無し

シャペロンによるポリグルタミン病治療戦略
小林靖, 足立弘明, 勝野雅央, 祖父江元
臨床化学, 2003年06月, 査読なし, 招待無し

血液培養サンプルのグラム染色により早期診断が可能であったリステリア脳膿瘍の1例
高野明美, 足立弘明, 水野正司, 川村久美子, 祖父江元
臨床神経学, 1999年11月, 査読なし, 招待無し

重症acute autonomic and sensory neuropathyの1例
足立弘明, 向井栄一郎, 奥田聡, 河田稔一
臨床神経学, 1998年07月, 査読なし, 招待無し

悪性症候群類似の症候を呈した全身こむら返り病の1例
足立弘明, 陸重雄, 藤城健一郎, 久留聡
臨床神経学, 1998年07月, 査読なし, 招待無し

ポリグルタミン病の診断と治療 (特集 神経筋疾患の最新研究治療情報)
足立弘明
難病と在宅ケア, 2007年06月, 査読なし, 招待無し