Oct. 2013
貝原守一賞

Soil bacterium Massilia secretes metabolites that promote Leptospira growth
Michinobu Yoshimura; Ryo Ozuru; Satoshi Miyahara; Fumiko Obata; Mitsumasa Saito; Takumi Sonoda; Yusuke Kurihara; Jason A. Papin; Glynis L. Kolling; Shin-ichi Yoshida; Kenji Hiromatsu
Apr. 2026

Cigarette smoking and long-term incidence of colorectal cancer subclassified by tumor-infiltrating myeloid cells: A prospective cohort study
Satoko Ugai; Hiroki Mizuno; Kosuke Matsuda; Atsushi Kondo; Yuxue Zhong; Nobuhiro Nakazawa; Satoshi Miyahara; Naoka Murakami; Sara A. Väyrynen; Andrew T. Chan; Mingyang Song; Marios Giannakis; Jeffrey A. Meyerhardt; Juha P. Väyrynen; Jonathan A. Nowak; Shuji Ogino; Tomotaka Ugai
Environmental Pollution, Apr. 2026

Tumor vessel phenotype in colorectal cancer microenvironment according to age at diagnosis
Kosuke Matsuda; Satoko Ugai; Satoshi Miyahara; Qian Yao; Jules Cazaubiel; Nobuhiro Nakazawa; Mayu Higashioka; Yuxue Zhong; Andrew T. Chan; Jeffrey A. Meyerhardt; Kimmie Ng; Mingyang Song; Juha P. Väyrynen; Jonathan A. Nowak; Marios Giannakis; Tomotaka Ugai; Shuji Ogino
British Journal of Cancer, Mar. 2026
Lead

Emulating visual evaluations in the microscopic agglutination test with deep learning.
Risa Nakano; Yuji Oyamada; Ryo Ozuru; Satoshi Miyahara; Michinobu Yoshimura; Kenji Hiromatsu
Journal of microbiological methods, Oct. 2025

アミノグリコシド修飾酵素遺伝子を持つMRSAに対するcontinuous local antibiotics perfusion(CLAP)の可能性
花田 修平; 善家 雄吉; 宮原 敏; 安藤 恒平; 圓尾 明弘; 齋藤 光正; 酒井 昭典
日本整形外科学会雑誌, Sep. 2025

Development of a PCR method for rapid detection of Leptospira from one microliter of whole blood
Satoshi Miyahara; Toru Yoneda; Satoshi Kimura; Kazumasa Fukuda; Midori Ogawa; Kazunori Kimitsuki; Nobuo Saito; Akira Nishizono; Mitsumasa Saito
Diagnostic Microbiology and Infectious Disease, May 2025, Reviewed, No invitation
Lead, Corresponding

Massiliaが産生するレプトスピラ属増殖促進因子の研究(Study on Growth-Promoting Factor for Leptospira Produced by the Massilia)
吉村 芳修; 尾鶴 亮; 園田 卓己; 宮原 敏; 齋藤 光正; Papin Jason; 小幡 史子; Kolling Glynis; 吉田 眞一; 廣松 賢治
日本細菌学雑誌, Apr. 2025

Massiliaが産生するレプトスピラ属増殖促進因子の研究(Study on Growth-Promoting Factor for Leptospira Produced by the Massilia)
吉村 芳修; 尾鶴 亮; 園田 卓己; 宮原 敏; 齋藤 光正; Papin Jason; 小幡 史子; Kolling Glynis; 吉田 眞一; 廣松 賢治
日本細菌学雑誌, Apr. 2025

Smoking habit and long-term colorectal cancer incidence by exome-wide mutational and neoantigen loads: evidence based on the prospective cohort incident-tumour biobank method.
Tsuyoshi Hamada; Tomotaka Ugai; Carino Gurjao; Satoko Ugai; Xuehong Zhang; Koichiro Haruki; Yasutoshi Takashima; Naohiko Akimoto; Mai Chan Lau; Kosuke Matsuda; Nobuhiro Nakazawa; Mayu Higashioka; Satoshi Miyahara; Keisuke Kosumi; Yohei Masugi; Li Liu; Yin Cao; Daniel Nevo; Molin Wang; Reiko Nishihara; Sachet A Shukla; Catherine J Wu; Levi A Garraway; Jeffrey A Meyerhardt; Edward L Giovannucci; Jonathan A Nowak; Charles S Fuchs; Andrew T Chan; Mingyang Song; Marios Giannakis; Shuji Ogino
BMJ oncology, 2025

Fibrinolytic treatment using recombinant tissue-type plasminogen activator (rt-PA) for staphylococcal infective endocarditis
Tomoya Takigawa; Satoshi Miyahara; Hiromu Ishii; Midori Ogawa; Kazumasa Fukuda; Yosuke Nishimura; Mitsumasa Saito
Microbial Pathogenesis, Dec. 2024

Effective biofilm eradication in MRSA isolates with aminoglycoside-modifying enzyme genes using high-concentration and prolonged gentamicin treatment
Kohei Ando; Satoshi Miyahara; Shuhei Hanada; Kazumasa Fukuda; Mitsumasa Saito; Akinori Sakai; Akihiro Maruo; Yukichi Zenke
Microbiology Spectrum, Oct. 2024
Corresponding

Reproducing Human Subjective Evaluation in the Microscopic Agglutination Test with Deep Learning
Satoshi Miyahara
BioRxiv, Apr. 2024

Non-purulent myositis caused by direct invasion of skeletal muscle tissue by Leptospira in a hamster model
Satoshi Miyahara; Hiroshi Mori; Kazumasa Fukuda; Midori Ogawa; Mitsumasa Saito
Infection and Immunity, Feb. 2024
Lead, Corresponding

感染性心内膜炎モデルラットを用いた抗菌薬/組換え組織型プラスミノーゲンアクチベーター(rt-PA)併用治療の有効性の検討
瀧川 友哉; 宮原 敏; 齋藤 光正; 西村 陽介
日本胸部外科学会定期学術集会, Oct. 2023

感染性心内膜炎モデルラットを用いた抗菌薬/組換え組織型プラスミノーゲンアクチベーター(rt-PA)併用治療の有効性の検討
瀧川 友哉; 宮原 敏; 齋藤 光正; 西村 陽介
日本胸部外科学会定期学術集会, Oct. 2023

Protective role of stratum corneum in percutaneous Leptospira infection in a hamster model
Tatsuma Asoh; Satoshi Miyahara; Sharon Yvette Angelina M. Villanueva; Takaaki Kanemaru; Tomoya Takigawa; Hiroshi Mori; Nina G. Gloriani; Shin-ichi Yoshida; Mitsumasa Saito
Microbial Pathogenesis, Sep. 2023

メチシリン耐性黄色ブドウ球菌臨床分離株に対するゲンタマイシンの最小バイオフィルム撲滅濃度と耐性遺伝子との関連
安藤 恒平; 善家 雄吉; 宮原 敏; 齋藤 光正; 濱田 大志; 佐藤 直人; 岡田 祥明; 篠原 大地; 酒井 昭典; 圓尾 明弘
日本整形外科学会雑誌, Aug. 2023

【腎臓症候群(第3版)-その他の腎臓疾患を含めて-】各種病態にみられる腎障害 感染症 レプトスピラ感染症(Weil病)
齋藤 光正; 丸岡 司; 二階堂 靖彦; 宮原 敏
日本臨床, Oct. 2022

Detection system for Legionella bacteria using photogate-type optical sensor
Yuto Honda; Ryosuke Ichikawa; Yong Joon Choi; Kensuke Murakami; Kazuhiro Takahashi; Toshihiko Noda; Kazuaki Sawada; Hiromu Ishii; Katsuyuki Machida; Hiroyuki Ito; Satoshi Miyahara; Yasuhiko Nikaido; Mitsumasa Saito
JAPANESE JOURNAL OF APPLIED PHYSICS, Jun. 2022

Dissemination of Leptospira into the intestinal tract resulting in fecal excretion in a hamster model of subcutaneous infection with Leptospirainterrogans.
Yoshinori Inamasu; Yasuhiko Nikaido; Satoshi Miyahara; Tsukasa Maruoka; Tomoya Takigawa; Midori Ogawa; Toshiyuki Nakayama; Masaru Harada; Mitsumasa Saito
Microbial pathogenesis, Apr. 2022

Correlation between renal distribution of leptospires during the acute phase and chronic renal dysfunction in a hamster model of infection with Leptospira interrogans
Tsukasa Maruoka; Yasuhiko Nikaido; Satoshi Miyahara; Eisuke Katafuchi; Yoshinori Inamasu; Midori Ogawa; Kazumasa Fukuda; Toshiyuki Nakayama; Takafumi Horishita; Mitsumasa Saito
PLOS Neglected Tropical Diseases, Jun. 2021

A machine learning model of microscopic agglutination test for diagnosis of leptospirosis.
Yuji Oyamada; Ryo Ozuru; Toshiyuki Masuzawa; Satoshi Miyahara; Yasuhiko Nikaido; Fumiko Obata; Mitsumasa Saito; Sharon Yvette Angelina M Villanueva; Jun Fujii
PloS one, 2021

Double recurrence of double cancers: Rhabdomyosarcoma and secondary AML
Naoki Kajita; Yuya Saito; Atsushi Makimoto; Satoshi Miyahara; Yuki Yuza
Pediatrics International, Jun. 2020

Case of primary thymic papillary adenocarcinoma associated with type AB thymoma and thymic cysts
Momoko Kitamura; Haruka Okada; Satoshi Miyahara; Atsumi Matsunaga; Yuichiro Kadomatsu; Shingo Itagaki; Takahiro Kiriu
Pathology International, Jun. 2020

Thoracic Spinal Chordoma Need to be Differentiated from the Bacteremia-associated Paravertebral Abscess
中山敬史; 吉川拓磨; 小原徹也; 金子 仁; 清水敬樹; 宮原 敏
胸部外科, May 2020, Reviewed

Misuse of Discharge Antimicrobial Prescription in the Emergency Department: An Observational Study at a Tertiary Care Center
Yasuaki Tagashira; Naofumi Yamane; Satoshi Miyahara; Azusa Orihara; Yuki Uehara; Keiichi Hiramatsu; Hitoshi Honda
Open Forum Infectious Diseases, Feb. 2019

Radiotherapy for electrolyte depletion syndrome caused by a rectal villous adenoma
Satoshi Miyahara; Shiori Ito; Dai Inoue; Shun Fujiwara; Daiki Yamada; Gen Maeda; Masamichi Kurihara; Yuko Hijioka; Kohei Shimoji; Ayano Nakazono; Junko Fujiki; Hideyuki Horike; Atsushi Yoshioka; Yuki Ogura; Shin Namiki
Progress of Digestive Endoscopy, Jun. 2018
Lead

Adipose tissue is the first colonization site of Leptospira interrogans in subcutaneously infected hamsters
Ryo Ozuru; Mitsumasa Saito; Takaaki Kanemaru; Satoshi Miyahara; Sharon Y. A. M. Villanueva; Gerald L. Murray; Ben Adler; Jun Fujii; Shin-ichi Yoshida
PLOS ONE, Feb. 2017

The usefulness of semi-solid medium in the isolation of highly virulentLeptospirastrains from wild rats in an urban area of Fukuoka, Japan
Mitsumasa Saito; Sharon Y. A. M. Villanueva; Toshiyuki Masuzawa; Yusuke Haraguchi; Shuhei Ita; Satoshi Miyahara; Ryo Ozuru; Takayoshi Yamaguchi; Michinobu Yoshimura; Mami Ikejiri; Natsumi Aramaki; Muhammad Yunus Amran; Lisa Tenriesa Muslich; Ken-ichiro Iida; Yasutake Yanagihara; Nina G. Gloriani; Shin-ichi Yoshida
Microbiology and Immunology, Jun. 2015

PCR and Culture Identification of Pathogenic Leptospira spp. from Coastal Soil in Leyte, Philippines, after a Storm Surge during Super Typhoon Haiyan (Yolanda)
Mitsumasa Saito; Satoshi Miyahara; Sharon Y. A. M. Villanueva; Natsumi Aramaki; Mami Ikejiri; Yoshie Kobayashi; Jonathan P. Guevarra; Toshiyuki Masuzawa; Nina G. Gloriani; Yasutake Yanagihara; Shin-ichi Yoshida
Applied and Environmental Microbiology, Nov. 2014
Lead

Destruction of the hepatocyte junction by intercellular invasion ofLeptospiracauses jaundice in a hamster model of Weil's disease
Satoshi Miyahara; Mitsumasa Saito; Takaaki Kanemaru; Sharon Y. A. M. Villanueva; Nina G. Gloriani; Shin-ichi Yoshida
International Journal of Experimental Pathology, Aug. 2014
Lead, Corresponding

High virulence in hamsters of four dominant Leptospira serovars isolated from rats in the Philippines
Sharon Y. A. M. Villanueva; Mitsumasa Saito; Yutaka Tsutsumi; Takaya Segawa; Rubelia A. Baterna; Antara Chakraborty; Tatsuma Asoh; Satoshi Miyahara; Yasutake Yanagihara; Lolita L. Cavinta; Nina G. Gloriani; Shin-ichi Yoshida
Microbiology, Feb. 2014

Leptospira idonii sp. nov., isolated from environmental water
Mitsumasa Saito; Sharon Y. A. M. Villanueva; Yoshiaki Kawamura; Ken-ichiro Iida; Junko Tomida; Takaaki Kanemaru; Eri Kohno; Satoshi Miyahara; Akiko Umeda; Kazunobu Amako; Nina G. Gloriani; Shin-ichi Yoshida
International Journal of Systematic and Evolutionary Microbiology, Jul. 2013

Comparative Analysis of Leptospira Strains Isolated from Environmental Soil and Water in the Philippines and Japan
Mitsumasa Saito; Sharon Y. A. M. Villanueva; Antara Chakraborty; Satoshi Miyahara; Takaya Segawa; Tatsuma Asoh; Ryo Ozuru; Nina G. Gloriani; Yasutake Yanagihara; Shin-ichi Yoshida
Applied and Environmental Microbiology, Jan. 2013

A novel combination of selective agents for isolation of Leptospira species
Antara Chakraborty; Satoshi Miyahara; Sharon Y.A.M. Villanueva; Mitsumasa Saito; Nina G. Gloriani; Shin-ichi Yoshida
Microbiology and Immunology, Jul. 2011

In Vitro Sensitivity and Resistance of 46 Leptospira Strains Isolated from Rats in the Philippines to 14 Antimicrobial Agents
Antara Chakraborty; Satoshi Miyahara; Sharon Y. A. M. Villanueva; Nina G. Gloriani; Shin-ichi Yoshida
Antimicrobial Agents and Chemotherapy, Dec. 2010

Non-purulent myositis caused by direct invasion of skeletal muscle tissue by Leptospira in a hamster model.
Miyahara Satoshi, Mori Hiroshi, Fukuda Kazumasa, Ogawa Midori, Saito Mitsumasa
Infection and immunity, Feb. 2024, Reviewed, No invitation
Lead, Corresponding

Detection system for Legionella bacteria using photogate-type optical sensor.
Yuto Honda, Ryosuke Ichikawa, Yong Joon Choi, Kensuke Murakami, Kazuhiro Takahashi, Toshihiko Noda, Kazuaki Sawada, Hiromu Ishii, Katsuyuki Machida, Hiroyuki Ito, Satoshi Miyahara, Yasuhiko Nikaido, Mitsumasa Saito
Japanese Journal of Applied Physics, Jun. 2022, Reviewed, Null

Fibrinolytic treatment using recombinant tissue-type plasminogen activator (rt-PA) for staphylococcal infective endocarditis.
Takigawa Tomoya, Miyahara Satoshi, Ishii Hiromu, Ogawa Midori, Fukuda Kazumasa, Nishimura Yosuke, Saito Mitsumasa
Microbial pathogenesis, Dec. 2024, Reviewed, Null

Protective role of stratum corneum in percutaneous Leptospira infection in a hamster model.
Asoh T, Miyahara S, Villanueva SYAM, Kanemaru T, Takigawa T, Mori H, Gloriani NG, Yoshida SI, Saito M.
Microbial pathogenesis, Sep. 2023, Reviewed, No invitation

Dissemination of Leptospira into the intestinal tract resulting in fecal excretion in a hamster model of subcutaneous infection with Leptospirainterrogans.
Inamasu Yoshinori, Nikaido Yasuhiko, Miyahara Satoshi, Maruoka Tsukasa, Takigawa Tomoya, Ogawa Midori, Nakayama Toshiyuki, Harada Masaru, Saito Mitsumasa
Microbial pathogenesis, Apr. 2022, Reviewed, Null

Effective biofilm eradication in MRSA isolates with aminoglycoside-modifying enzyme genes using high-concentration and prolonged gentamicin treatment.
Ando Kohei, Miyahara Satoshi, Hanada Shuhei, Fukuda Kazumasa, Saito Mitsumasa, Sakai Akinori, Maruo Akihiro, Zenke Yukichi
Microbiology spectrum, Oct. 2024, Reviewed, Null

Correlation between renal distribution of leptospires during the acute phase and chronic renal dysfunction in a hamster model of infection with Leptospira interrogans.
Maruoka Tsukasa, Nikaido Yasuhiko, Miyahara Satoshi, Katafuchi Eisuke, Inamasu Yoshinori, Ogawa Midori, Fukuda Kazumasa, Nakayama Toshiyuki, Horishita Takafumi, Saito Mitsumasa
PLoS neglected tropical diseases, Jun. 2021, Reviewed, No invitation

Case of primary thymic papillary adenocarcinoma associated with type AB thymoma and thymic cysts.
Kitamura Momoko, Okada Haruka, Miyahara Satoshi, Matsunaga Atsumi, Kadomatsu Yuichiro, Itagaki Shingo, Kiriu Takahiro
Pathology international, Jun. 2020, Reviewed, Null

Double recurrence of double cancers: Rhabdomyosarcoma and secondary AML.
Kajita Naoki, Saito Yuya, Makimoto Atsushi, Miyahara Satoshi, Yuza Yuki
Pediatrics international : official journal of the Japan Pediatric Society, Jun. 2020, Reviewed, Null

A machine learning model of microscopic agglutination test for diagnosis of leptospirosis.
Oyamada Yuji, Ozuru Ryo, Masuzawa Toshiyuki, Miyahara Satoshi, Nikaido Yasuhiko, Obata Fumiko, Saito Mitsumasa, Villanueva Sharon Yvette Angelina M, Fujii Jun
PloS one, Nov. 2021, Reviewed, Null

CLAPによる骨軟部感染抑制の実際/ ゲンタマイシンの作用機序と薬剤耐性機構
齋藤光正, 宮原敏, 安藤恒平, 善家雄吉, Joint work
全日本病院出版会, Aug. 2022

レプトスピラ感染症（Weil病）
齋藤光正, 丸岡司, 二階堂靖彦, 宮原敏, Joint work
日本臨牀社, Aug. 2022