Occupational Health Journal
Compilation of background data of occupational Physician to assist with the analysis of bottleneck factor of supply in each region.
Occupational Health Journal, Nov. 2025, Invited
Lead, Last, Corresponding

Survey and Analysis of Supply and Demand for Occupational Physicians, and Hindering and Improvement Factors of the Supply: Introduction – Purpose and Overview of This Study
一瀬 豊日
Occupational Health Journal, Nov. 2025, Invited
Lead, Corresponding

The effect of mask fit test on the association between the concentration of metals in biological samples and the results of time-weighted average personal exposure: A study on Japanese male welders.
Mayumi Tsuji; Hajime Hori; Chihaya Koriyama; Rie Tanaka; Toyohi Isse; Yasuhiro Ishihara; Tsunetoshi Ishizuka; Wataru Hasegawa; Motohide Goto; Kazuhiro Yatera; Naoki Kunugita; Mami Kuwamura; Toshihide Sakuragi; Yoshiko Yasumura; Megumi Yamamoto; Susumu Ueno
Journal of occupational health, 2023

Associations between welding fume exposure and neurological function in Japanese male welders and non-welders.
Mayumi Tsuji; Chihaya Koriyama; Yasuhiro Ishihara; Toyohi Isse; Tsunetoshi Ishizuka; Wataru Hasegawa; Motohide Goto; Rie Tanaka; Noriaki Kakiuchi; Hajime Hori; Kazuhiro Yatera; Naoki Kunugita; Megumi Yamamoto; Toshihide Sakuragi; Yoshiko Yasumura; Maori Kono; Mami Kuwamura; Kyoko Kitagawa; Susumu Ueno
Journal of occupational health, Jan. 2023

現代の若手整形外科医の育成 若手整形外科医の育成 労働衛生の観点から
川崎 展; 櫻澤 博文; 一瀬 豊日; 善家 雄吉; 中村 英一郎; 酒井 昭典
日本整形外科学会雑誌, Oct. 2022

呼吸用保護具の定量的フィットテストから得られた知見 金属アーク溶接等作業に従事する労働者を対象とした調査から
辻 真弓; 安村 美子; 保利 一; 上野 晋; 一瀬 豊日; 後藤 元秀; 石塚 恒年; 長谷川 渉
産業医学ジャーナル, Sep. 2022

Retention among full-time occupational physicians in Japan.
Koike S; Isse T; Kawaguchi H; Ogawa M
Occup Med (Lond), Sep. 2018, Reviewed, No invitation

産業医の需要と供給の諸条件と調整について（平成29年度産業医需要供給実態調査事業結果の概要）
産業医需要供給実態調査事業委員会; 文責(尾澤英夫; 一瀬豊日; 池上和範
産業医学ジャーナル, Jul. 2018, Not reviewed, Invited

Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory.
Tsuji M; Ishihara Y; Isse T; Koriyama C; Yamamoto M; Kakiuchi N; Yu HS; Tanaka M; Tsuchiya T; Ohta M; Tanaka R; Kawamoto T
Environ Health Prev Med, Jan. 2018, Reviewed, No invitation

Changes of working responsibilities and intentions of industrial physicians (graduates of university of occupational and environmental health, Japan) in a comparison between 2001, 2008 and 2015 questionnaire analyses
Hayato Nakamura; Toyohi Isse; Akinori Sakai
Journal of UOEH, 2017, Reviewed, No invitation

Comparison of IgG against plastic resin in workerswith and without chemical dermatitis
Toshihiro Kawamoto; Mayumi Tsuji; Toyohi Isse
BMC PUBLIC HEALTH, Sep. 2015, Reviewed, No invitation

ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice
Kamaljit K. Chaudhry; Geetha Samak; Pradeep K. Shukla; Hina Mir; Ruchika Gangwar; Bhargavi Manda; Toyohi Isse; Toshihiro Kawamoto; Mikko Salaspuro; Pertti Kaihovaara; Paula Dietrich; Ioannis Dragatsis; Laura E. Nagy; Radha Krishna Rao
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, Aug. 2015, Reviewed, No invitation

Mitochondrial Aldehyde Dehydrogenase 2 Plays Protective Roles in Heart Failure After Myocardial Infarction via Suppression of the Cytosolic JNK/p53 Pathway in Mice
Aijun Sun; Yunzeng Zou; Ping Wang; Danling Xu; Hui Gong; Shijun Wang; Yingjie Qin; Peng Zhang; Yunqin Chen; Mutsuo Harada; Toyoshi Isse; Toshihiro Kawamoto; Huizhi Fan; Pengyuan Yang; Hiroshi Akazawa; Toshio Nagai; Hiroyuki Takano; Peipei Ping; Issei Komuro; Junbo Ge
JOURNAL OF THE AMERICAN HEART ASSOCIATION, Oct. 2014, Reviewed, No invitation

Effect of Korean pear (Pyruspyrifolia cv. Shingo) juice on hangover severity following alcohol consumption
Ho-Sun Lee; Toyohi Isse; Toshihiro Kawamoto; Hyun Wook Baik; Jong Y. Park; Mihi Yang
Food and Chemical Toxicology, Aug. 2013, Reviewed, No invitation

Disruption of aldehyde dehydrogenase 2 gene results in altered cortical bone structure and increased cortical bone mineral density in the femoral diaphysis of mice
Takuto Tsuchiya; Akinori Sakai; Kunitaka Menuki; Toshiharu Mori; Yoshinori Takeuchi; Shinkichi Kanoh; Hajime Utsunomiya; Teppei Murai; Toyohi Isse; Toshihiro Kawamoto; Toshitaka Nakamura
BONE, Apr. 2013, Reviewed, No invitation

University of occupational and environmental health, Japan: 2013 Alumni physician statistics
Toyohi Isse; Hayato Nakamura; Kenji Hachisuka
Journal of UOEH, 2013, Reviewed, No invitation

Effects and Action Mechanisms of Korean Pear (Pyrus pyrifolia cv. Shingo) on Alcohol Detoxification
Ho-Sun Lee; Toyoshi Isse; Toshihiro Kawamoto; Hyun-Su Woo; An Keun Kim; Jong Y. Park; Mihi Yang
PHYTOTHERAPY RESEARCH, Nov. 2012, Reviewed, No invitation

The effect of ethanol on the formation of N-2-ethylidene-dG adducts in mice: implications for alcohol-related carcinogenicity of the oral cavity and esophagus
Hsu-Sheng Yu; Tsunehiro Oyama; Tomonari Matsuda; Toyohi Isse; Tetsunosuke Yamaguchi; Masayuki Tanaka; Mayumi Tsuji; Toshihiro Kawamoto
BIOMARKERS, May 2012, Reviewed, No invitation

Aldehyde Dehydrogenase-2 Deficiency Aggravates Cardiac Dysfunction Elicited by Endoplasmic Reticulum Stress Induction
Jianquan Liao; Aijun Sun; Yeqing Xie; Toyoshi Isse; Toshihiro Kawamoto; Yunzeng Zou; Junbo Ge
MOLECULAR MEDICINE, May 2012, Reviewed, No invitation

Turnover of Full-time Occupational Physicians in Japan in the Period 2002–2008: A Component Model Survey
Toyohi Isse; Hayato Nakamura; Kenji Hachisuka
SANGYO EISEIGAKU ZASSHI, 2012, Reviewed, No invitation

Reduced bone formation in alcohol-induced osteopenia is associated with elevated p21 expression in bone marrow cells in aldehyde dehydrogenase 2-disrupted mice
Yuki Shimizu; Akinori Sakai; Kunitaka Menuki; Toshiharu Mori; Toyohi Isse; Tsunehiro Oyama; Toshihiro Kawamoto; Toshitaka Nakamura
BONE, May 2011, Reviewed, No invitation

Formation of acetaldehyde-derived DNA adducts due to alcohol exposure
Hsu-Sheng Yu; Tsunehiro Oyama; Toyohi Isse; Kyoko Kitagawa; Thi-Thu-Phuong Pham; Masayuki Tanaka; Toshihiro Kawamoto
CHEMICO-BIOLOGICAL INTERACTIONS, Dec. 2010, Reviewed, No invitation

Effects of acetaldehyde inhalation in mitochondrial aldehyde dehydrogenase deficient mice (Aldh2-/-)
Tsunehiro Oyama; Haruna Nagayoshi; Tomonari Matsuda; Megumi Oka; Toyohi Isse; Hsu-Sheng Yu; Thi-Thu-Phuong Pham; Masayuki Tanaka; Norio Kagawa; Kazuhiro Kaneko; Toshihiro Kawamoto
Frontiers in Bioscience - Elite, Jan. 2010, Reviewed, No invitation

Necessary number of dedicated industrial physicians in japan: Evaluated from the establishment and enterprise census
Toyohi Isse; Hayato Nakamura; Yoshiki Tokura
Journal of UOEH, 2010, Reviewed, No invitation

Cholinergic alterations following alcohol exposure in the frontal cortex of Aldh2-deficient mice models.
Mostofa Jamal; Kiyoshi Ameno; Takanori Miki; Weihuan Wang; Mitsuru Kumihashi; Toyohi Isse; Toshihiro Kawamoto; Kyoko Kitagawa; Keiichi Nakayama; Iwao Ijiri; Hiroshi Kinoshita
Brain research, Oct. 2009, Reviewed, No invitation

Application of Tryptophan Fluorescence to Assess Sensitizing Potentials of Chemicals
Thi-Thu-Phuong Pham; Tsunehiro Oyama; Toyohi Isse; Toshihiro Kawamoto
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, Oct. 2009, Reviewed, No invitation

特性不安の高低による、アルコール摂取後の血中アセトアルデヒド濃度と不安との関連
荒薦 優子; 一瀬 豊日; 伊藤 裕康; 尾久 征三; 池上 和範; 鈴木 貴代美; 真船 浩介; 廣 尚典; 永田 頌史
産業衛生学雑誌, Mar. 2009, Reviewed, No invitation

Occupational asthma and low molecule chemicals
一瀬 豊日; 小山 倫浩; 川本 俊弘
Journal of preventive medicine, Feb. 2009, Reviewed, Invited
Lead

Hazardous environmental factors enhance impairment of liver function in HBV and HCV hepatitis
Yasunori Yashima; Tsunehiro Oyama; Thi Thu Phuong Pham; Tetunosuke Yamaguchi; Rie Narai; Toyohi Isse; Hidetaka Uramoto; Kenji Sugio; Kosei Yasumoto; Norio Kagawa; Toshihiro Kawamoto
FRONTIERS IN BIOSCIENCE, Jan. 2009, Reviewed, No invitation

Changes of working responsibilities and intentions of industrial physicians who are graduates of university of occupational and Environmental health, Japan, in 2001 and 2008 questionnaire analyses
Hayato Nakamura; Toyohi Isse; Tetsuro Matsumoto; Yoshiki Tokura
Journal of UOEH, 2009, Reviewed, No invitation

Characteristics of aldehyde dehydrogenase 2 (Aldh2) knockout mice
Hsu-Sheng Yu; Tsunehiro Oyama; Toyohi Isse; Kyoko Kitakawa; Masanori Ogawa; Thi-Thu-Phuong Pham; Toshihiro Kawamoto
TOXICOLOGY MECHANISMS AND METHODS, 2009, Reviewed, No invitation

Effects of 5-week ethanol feeding on the liver of aldehyde dehydrogenase 2 knockout mice
Akiko Matsumoto; Toshihiro Kawamoto; Fumihiro Mutoh; Toyohi Isse; Tsunehiro Oyama; Kyoko Kitagawa; Keilchi I. Nakayama; Masayoshi Ichiba
PHARMACOGENETICS AND GENOMICS, Oct. 2008, Reviewed, No invitation

Expression of Cytochrome P450 in non-small cell lung cancer
Tsunehiro Oyama; Kenji Sugio; Toyohi Isse; Akiko Matsumoto; Naohiro Nose; Hidetaka Uramoto; Tadahiro Nozoe; Masaru Morita; Norio Kagawa; Toshihiro Osaki; Manabu Muto; Kosei Yasumoto; Toshihiro Kawamoto
FRONTIERS IN BIOSCIENCE, May 2008, Reviewed, No invitation

Increased frequencies of micronucleated reticulocytes and T-cell receptor mutation in Aldh2 knockout mice exposed to acetaldehyde
Naoki Kunugita; Toyohi Isse; Tsunehiro Oyama; Kyoko Kitagawa; Masanori Ogawa; Tetsunosuke Yamaguchi; Tsuyoshi Kinaga; Toshihiro Kawamoto
JOURNAL OF TOXICOLOGICAL SCIENCES, Feb. 2008, Reviewed, No invitation

Methods and rationale for keeping records of hepatitis virus testing in Japanese workplaces.
Narai R; Oyama T; Isse T; Moriguchi J; Yashima Y; Fujino A; Horie S; Kawamoto T
Sangyo eiseigaku zasshi = Journal of occupational health, Jan. 2008, Reviewed, No invitation

わが国の職域における肝炎ウイルス検査の実施方法、結果の保管方法および産業医の考え方
奈良井 理恵; 小山 倫浩; 一瀬 豊日; 森口 次郎; 八嶋 康典; 藤野 昭宏; 堀江 正知; 川本 俊弘
産業衛生学雑誌, Jan. 2008

Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice
Akiko Matsumoto; Toshihiro Kawamoto; Mikako Horita; Tatsuya Takahashia; Toyohi Isse; Tsunehiro Oyama; Masayoshi Ichiba
ALCOHOL, Dec. 2007, Reviewed, No invitation

A pirot study on subacute ethanol treatment of ALDH2 KO mice
Tsunehiro Oyama; Yong-Dae Kim; Toyohi Isse; Pham Thi Thu Phuong; Masanori Ogawa; Tetsunosuke Yamaguchi; Tsuyoshi Kinaga; Yasunori Yashima; Heon Kim; Toshihiro Kawamoto
Journal of Toxicological Sciences, Oct. 2007, Reviewed, No invitation

International comparison of sensitizing chemical substances
Tomoe Murakami; Tsunehiro Oyma; Toyohi Isse; Rie Narai; Maki Kanaoka; Thi-Thu-Phuong Pham; Toshihiro Kawamoto
Journal of UOEH, Sep. 2007, Reviewed, No invitation

Ethanol-induced oxidative DNA damage and CYP2EI expression in liver tissue of Aldh2 knockout mice
Yong-Dae Kim; Sang-Yong Eom; Masanori Ogawa; Tsunehiro Oyama; Toyohi Isse; Jong-Won Kang; Yan Wei Hang; Toshihiro Kawamoto; Heon Kim
JOURNAL OF OCCUPATIONAL HEALTH, Sep. 2007, Reviewed, No invitation

Activities of antioxidant enzymes induced by ethanol exposure in Aldehyde dehydrogenase 2 knockout mice
Sang-Yong Eom; Yan Wei Zhanga; Masanori Ogawa; Tsunehiro Oyama; Toyohi Isse; Jong-Won Kanga; Lee Chung-Jong; Yong-Dae Kim; Toshihiro Kawamoto
JOURNAL OF HEALTH SCIENCE, Aug. 2007, Reviewed, No invitation

Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis
Tsunehiro Oyama; Kenji Sugio; Hidetaka Uramoto; Teruo Iwata; Takamitsu Onitsuka; Toyohi Isse; Tadahiro Nozoe; Norio Kagawa; Kosei Yasumoto; Toshihiro Kawamoto
FRONTIERS IN BIOSCIENCE, May 2007, Reviewed, No invitation

Effects of lifestyle on urinary 1-hydroxypyrene concentration
Toshihiro Kawamoto; Mihi Yang; Yong-Dae Kim; Heon Kim; Tsunehiro Oyama; Toyohi Isse; Koji Matsuno; Takahiko Katoh; Iwao Uchiyama
JOURNAL OF OCCUPATIONAL HEALTH, May 2007, Reviewed, No invitation

Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2(-/-) mice
P. Wenzel; U. Hink; M. Oelze; A. Seeling; T. Isse; K. Bruns; L. Steinhoff; M. Brandt; A. L. Kleschyov; E. Schulz; K. Lange; H. Weiner; J. Lehmann; K. J. Lackner; T. Kawamoto; T. Muenzel; A. Daiber
BRITISH JOURNAL OF PHARMACOLOGY, Feb. 2007, Reviewed, No invitation

Lack of aldehyde dehydrogenase ameliorates oxidative stress induced by single-dose ethanol administration in mouse liver
Akiko Matsumoto; Masayoshi Ichiba; Mikako Horita; Zenko Yamashita; Tatsuya Takahashi; Toyohi Isse; Tsunehiro Oyama; Toshihiro Kawamoto; Katsumaro Tomokuni
ALCOHOL, Feb. 2007, Reviewed, No invitation

Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice
Tsunehiro Oyama; Toyohi Isse; Masanori Ogawa; Manabu Muto; Iwao Uchiyama; Toshihiro Kawamoto
FRONTIERS IN BIOSCIENCE, Jan. 2007, Reviewed, No invitation

A comparison of covalent binding of ethanol metabolites to DNA according to Aldh2 genotype
Masanori Ogawa; Tsunehiro Oyama; Toyohi Isse; Koichi Saito; Yoshitaka Tomigahara; Yoko Endo; Toshihiro Kawamoto
TOXICOLOGY LETTERS, Jan. 2007, Reviewed, No invitation

HBV- and HCV-infected workers in the Japanese workplace
Rie Narai; Tsunehiro Oyama; Masanori Ogawa; Tetsunosuke Yamaguchi; Tsuyoshi Kinaga; Tomoe Murakami; Toyohi Isse; Shin-ichi Ozaki; Yasunori Yashima; Ken Okabayashi; Hideo Ochiai; Keiichiro Yarita; Akihiro Fujino; Toshihiro Kawamoto
JOURNAL OF OCCUPATIONAL HEALTH, Jan. 2007, Reviewed, No invitation

International comparison of criteria for evaluating sensitization of PRTR-designated chemical substances
Tomoe Murakami; Tsunehiro Oyama; Toyohi Isse; Masanori Ogawa; Takuya Sugie; Toshihiro Kawamoto
Environmental Health and Preventive Medicine, 2007, Reviewed, No invitation

禁煙プログラムとCYP2A6遺伝子多型
尾崎 真一; 河野 慶三; 小山 倫浩; 八嶋 康典; 一瀬 豊日; 村上 朋絵; 山口 哲右; 小川 真規; 木長 健; 川本 俊弘
産業衛生学雑誌, Nov. 2006, Reviewed, No invitation

Smoking cessation program and CYP2A6 polymorphism
Shinichi Ozaki; Tsunehiro Oyama; Toyohi Isse; Norio Kagawa; Hidetaka Uramoto; Kenji Sugio; Kosei Yasumoto; Keizo Kono; Toshihiro Kawamoto
FRONTIERS IN BIOSCIENCE-LANDMARK, Sep. 2006, Reviewed, No invitation

Hemoglobin adducts as a marker of exposure to chemical substances, especially PRTR class I designated chemical substances
Masanori Ogawa; Tsunehiro Oyama; Toyohi Isse; Tetsunosuke Yamaguchi; Tomoe Murakami; Yoko Endo; Toshihiro Kawamoto
JOURNAL OF OCCUPATIONAL HEALTH, Sep. 2006, Reviewed, No invitation

Evidence-Based Prevention (EBP): A review of cytochrome P450 expression in the bronchial epithelium and new approach to lung cancer prevention
Tsunehiro Oyama; Toyohi Isse; Tomoe Murakami; Rie Suzuki-Narai; Masanori Ogawa; Tetsunosuke Yamaguchi; Tsuyoshi Kinaga; Yasunori Yashima; Shinichi Ozaki; Yong-Dae Kim; Heon Kim; Toshihiro Kawamoto
Environmental Health and Preventive Medicine, May 2006, Reviewed, No invitation

Effects of LPS stimulation on the expression of prostaglandin carriers in the cells of the blood-brain and blood-cerebrospinal fluid barriers
B Kis; T Isse; JA Snipes; L Chen; H Yamashita; Y Ueta; DW Busija
JOURNAL OF APPLIED PHYSIOLOGY, Apr. 2006, Reviewed, No invitation

Urinary 8-hydoxydeoxyguanosine (8-OHdG) and plasma malondialdehyde (MDA) levels in Aldh2 knock-out mice under acetaldehyde exposure
M Ogawa; T Isse; T Oyama; N Kunugita; T Yamaguchi; T Kinaga; R Narai; A Matsumoto; YD Kim; H Kim; Uchiyama, I; T Kawamoto
INDUSTRIAL HEALTH, Jan. 2006, Reviewed, No invitation

1. Recent biomarker studies mainly focusing on "-omics"(Prospect and Status of Biomarker Research in Japan,Symposia by Scientific Committee,Occupational Health in the Age of Decentralization Reform in Japan,The 79th Annual Meeting of Japan Society for Occupational Health)
Kawamoto T.
Sangyo Eiseigaku Zasshi, 2006

Acetaldehyde elimination changes in transgenic mice lacking aldehyde dehydrogenase 2 activity
T Isse; T Oyama; K Matsuno; K Kitagawa; M Ogawa; T Kinaga; R Suzuki-Narai; T Yamaguchi; Uchiyama, I; T Kawamoto
Enzymology and Molecular Biology of Carbonyl Metabolism 12, 2006, Reviewed, No invitation

Aldehyde dehydrogenase 2 activity affects symptoms produced by an intraperitoneal acetaldehyde injection, but not acetaldehyde lethality
Toyohi Isse; Tsunehiro Oyama; Koji Matsuno; Iwao Uchiyama; Toshihiro Kawamoto
Journal of Toxicological Sciences, Dec. 2005, Reviewed, No invitation

Paired acute inhalation test reveals that acetaldehyde toxicity is higher in aldehyde dehydrogenase 2 knockout mice than in wild-type mice
Toyohi Isse; Tsunchiro Oyama; Koji Matsuno; Masanori Ogawa; Ric Narai-Suzuki; Tetsunosuke Yamaguchi; Tomoe Murakami; Tsuyoshi Kinaga; Iwao Uchiyama; Toshihiro Kawamoto
Journal of Toxicological Sciences, Dec. 2005, Reviewed, No invitation

Aldehyde dehydrogenase 2 gene targeting mouse lacking enzyme activity shows high acetaldehyde level in blood, brain, and liver after ethanol gavages
T Isse; K Matsuno; T Oyama; K Kitagawa; T Kawamoto
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, Nov. 2005, Reviewed, No invitation

Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer
T Oyama; M Morita; T Isse; N Kagawa; S Nakata; T So; M Mizukami; Y Ichiki; K Ono; M Sugaya; H Uramoto; T Yoshimatsu; T Hanagiri; K Sugio; T Kawamoto; K Yasumoto
FRONTIERS IN BIOSCIENCE, May 2005, Reviewed, No invitation

Expression levels of hepatic cytochrome P450 enzymes in Aldh2-deficient mice following ethanol exposure: a pilot study
YD Kim; T Oyama; T Isse; H Kim; T Kawamoto
ARCHIVES OF TOXICOLOGY, Apr. 2005, Reviewed, No invitation

アセトアルデヒド500ppm全身暴露におけるA1dh2ノックアウトマウス肝臓内ALDH2,CYP2E1発現の変動
木長 健; 小山 倫浩; 一瀬 豊日; 小川 真規; 山口 哲右; 鈴木 理恵; 北川 恭子; 川本 俊弘
産業医科大学雑誌, Mar. 2005, Reviewed, No invitation

職場におけるウイルス性肝炎の健康管理(第1報) 感染者の発見経緯から
奈良井 理恵; 小山 倫浩; 一瀬 豊日; 井上 正岩; 岡林 賢; 尾崎 真一; 落合 秀夫; 森口 次郎; 八嶋 康典; 小川 真規; 木長 健; 村上 朋絵; 山口 哲右; 川本 俊弘
産業衛生学雑誌, Mar. 2005, Reviewed, No invitation

Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism
T Oyama; T Isse; N Kagawa; T Kinaga; YD Kim; M Morita; K Sugio; H Weiner; K Yasumoto; T Kawamoto
FRONTIERS IN BIOSCIENCE, Jan. 2005, Reviewed, No invitation

Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer.
Tsunehiro Oyama; Masaru Morita; Toyohi Isse; Norio Kagawa; Shyouzi Nakata; Tetsuya So; Makiko Mizukami; Yoshinobu Ichiki; Kenji Ono; Masakazu Sugaya; Hidetaka Uramoto; Takashi Yoshimatsu; Takeshi Hanagiri; Kenji Sugio; Toshihiro Kawamoto; Kosei Yasumoto
Frontiers in bioscience : a journal and virtual library, 2005

Expression of cytochrome P450 in tumor tissues and its association with cancer development
T Oyama; N Kagawa; N Kunugita; K Kitagawa; M Ogawa; T Yamaguchi; R Suzuki; T Kinaga; Y Yashima; S Ozaki; T Isse; YD Kim; H Kim; T Kawamoto
FRONTIERS IN BIOSCIENCE-LANDMARK, May 2004, Reviewed, No invitation

Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene
YD Kim; H Todoroki; T Oyama; T Isse; A Matsumoto; T Yamaguchi; H Kim; Uchiyama, I; T Kawamoto
ENVIRONMENTAL RESEARCH, Mar. 2004, Reviewed, No invitation

肝炎労働者の急性増悪と業務内容
鈴木 理恵; 小山 倫浩; 一瀬 豊日; 欅田 尚樹; 尾崎 真一; 八嶋 康典; 山口 哲右; 木長 健; 小川 真規; 川本 俊弘
日本衛生学雑誌, Mar. 2004, Reviewed, No invitation

事業所における肝炎労働者の情報管理方法
鈴木 理恵; 小山 倫浩; 一瀬 豊日; 森口 次郎; 岡林 賢; 井上 正岩; 落合 秀夫; 尾崎 真一; 八嶋 康典; 欅田 尚樹; 小川 真規; 山口 哲右; 木長 健; 川本 俊弘
産業衛生学雑誌, Mar. 2004, Reviewed, No invitation

Putative cyclooxygenase-3 expression in rat brain cells
B Kis; JA Snipes; T Isse; T Nagy; DW Busija
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Nov. 2003, Reviewed, No invitation

アルデヒド脱水素酵素2(Aldh2)ノックアウトマウスのアルコール医学研究への応用
川本 俊弘; 北川 恭子; 一瀬 豊日; 松本 明子; 山口 哲右; 鈴木 理恵; 小川 真規; 木長 健; 松野 康二; 欅田 尚樹; 小山 倫浩
日本アルコール精神医学雑誌, Aug. 2003, Not reviewed, No invitation

Pleomorphic carcinoma: report of a case with massive pleural effusion and asbestos particles.
Oyama T; Osaki T; Isse T; Yashima Y; Ozaki S; Nakata S; Uramoto H; Sugaya M; Yasuda M; Yamashita T; Inoue M; Takenoyam M; Hanagiri T; Sugio K; Hamada T; Kawamoto T; Yasumoto K
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, Apr. 2003, Reviewed, No invitation

産業衛生に必要な化学物質代謝知識アルキルフェノール類
小山 倫浩; 一瀬 豊日
産業衛生学雑誌 = Journal of occupational health, Mar. 2003

Evidence-based prevention (EBP): Approach to lung cancer prevention based on cytochrome 1A1 and cytochrome 2E1 polymorphism
T Oyama; A Matsumoto; T Isse; YD Kim; S Ozaki; T Osaki; K Sugio; K Yasumoto; T Kawamoto
ANTICANCER RESEARCH, Mar. 2003, Reviewed, No invitation

Lung cancer andCYP1A1 orGSTM1 polymorphisms.
Oyama T; Kagawa N; Kim YD; Matsumoto A; Isse T; Kawamoto T
Environmental health and preventive medicine, Jan. 2003, Reviewed, No invitation

Bisphenol A levels in human urine
A Matsumoto; N Kunugita; K Kitagawa; T Isse; T Oyama; GL Foureman; M Morita; T Kawamoto
ENVIRONMENTAL HEALTH PERSPECTIVES, Jan. 2003, Reviewed, No invitation

Case-case study comparing the usefulness of serum trace elements (Cu, Zn and Se) and tumor markers (CEA, SCC and SLX) in non-small cell lung cancer patients
T Oyama; T Kawamoto; K Matsuno; T Osaki; A Matsumoto; T Isse; S Nakata; S Ozaki; M Sugaya; M Yasuda; T Yamashita; M Takenoyama; K Sugio; K Yasumoto
ANTICANCER RESEARCH, Jan. 2003, Reviewed, No invitation

Effects of genetic polymorphism of drug metabolizing enzymes on smoking and drinking
Kawamoto, T; Isse, T; Kunugita, N; Yang M; Kitagawa, K; Suenaga, R; Matsumoto, A; Oyama, T
J. UOEH, 2003, Not reviewed, No invitation

Evidence based prevention (EBP): Evidence-based approach to prevention of lung cancer by application of cytochrome 2E1 polymorphism
Tsunehiro Oyama; Toshihiro Kawamoto; Akiko Matsumoto; Toyohi Isse; Shinichi Ozaki; Kosei Yasumoto
Journal of UOEH, Dec. 2002, Reviewed, No invitation

Diminished alcohol preference in transgenic mice lacking aldehyde dehydrogenase activity
T Isse; T Oyama; K Kitagawa; K Matsuno; A Matsumoto; A Yoshida; K Nakayama; K Nakayama; T Kawamoto
PHARMACOGENETICS, Nov. 2002, Reviewed, No invitation

Cerebral endothelial cells are a major source of adrenomedullin
B Kis; H Kaiya; R Nishi; MA Deli; CS Abraham; T Yanagita; T Isse; S Gotoh; H Kobayashi; A Wada; M Niwa; K Kangawa; J Greenwood; H Yamashita; Y Ueta
JOURNAL OF NEUROENDOCRINOLOGY, Apr. 2002, Reviewed, No invitation

アセトアルデヒド脱水素酵素(Aldh)2ノックアウトマウスは低アルコール嗜好性を示す
一瀬豊日; 北川恭子; 松本明子; 吉田昭; 川本俊弘; 中山啓子; 中山啓一
産業医科大学雑誌, Mar. 2002, Not reviewed, No invitation

G107 アスベスト小体と大量の胸水貯留を認めた肺原発pleomorphic carcinomaの一例
小山 倫浩; 松本 明子; 一瀬 豊日; 川本 俊弘
産業衛生学雑誌, 2002

1.当事業所における禁煙サポートの検討(平成14年度日本産業衛生学会九州地方会)(地方会・研究会記録)
尾崎 真一; 河野 慶三; 小山 倫浩; 松本 明子; 一瀬 豊日; 川本 俊弘
産業衛生学雑誌, 2002

32.Aldh2ノックアウトマウスにおけるエタノール投与後の肝内薬物代謝酵素の変動(平成14年度日本産業衛生学会九州地方会)(地方会・研究会記録)
松本 明子; 小山 倫浩; 一瀬 豊日; 川本 俊弘
産業衛生学雑誌, 2002

喫煙による気管支上皮内チトクロームP450 2E1酵素の誘導 : 気管支上皮内CYP2E1酵素発現は肺癌感受性のバイオマーカーとなるか?
小山 倫浩; 松本 明子; 一瀬 豊日; 川本 俊弘
産業衛生学雑誌, 2002

飲酒後の生体内アセトアルデヒド濃度 : アルデヒド脱水素酵素(Aldh)2遺伝子欠損マウスを用いた検討(第29回生物学的モニタリング・バイオマーカー研究会)(地方会・研究会記録)
一瀬 豊日; 松本 明子; 小山 倫浩; 金 容大; 川本 俊弘
産業衛生学雑誌, 2002

Adrenomedullin regulates blood-brain barriers functions in vitro
B Kis; MA Deli; H Kobayashi; CS Abraham; T Yanagita; H Kaiya; T Isse; R Nishi; S Gotoh; K Kangawa; A Wada; J Greenwood; M Niwa; H Yamashita; Y Ueta
NEUROREPORT, Dec. 2001, Reviewed, No invitation

Preferential potentiation by nitric oxide of spontaneous inhibitory postsynaptic currents in rat supraoptic neurones
M Ozaki; Shibuya, I; N Kabashima; T Isse; J Noguchi; Y Ueta; Y Inoue; A Shigematsu; H Yamashita
JOURNAL OF NEUROENDOCRINOLOGY, Mar. 2000, Reviewed, No invitation

Increase of urocortin-like immunoreactivity in the supraoptic nucleus of Dahl rats given a high salt diet
Y Hara; Y Ueta; T Isse; R Serino; Shibuya, I; Y Hattori; H Yamashita
NEUROSCIENCE LETTERS, Jan. 2000, Reviewed, No invitation

Effects of leptin on fasting-induced inhibition of neuronal nitric oxide synthase mRNA in the paraventricular and supraoptic nuclei of rats
T Isse; Y Ueta; R Serino; J Noguchi; Y Yamamoto; M Nomura; Shibuya, I; SL Lightman; H Yamashita
BRAIN RESEARCH, Nov. 1999, Reviewed, No invitation

Adrenomedullin-like immunoreactivity in the rat hypothalamoneurohypophysial tract
Y Ueta; Y Hara; VS Setiadji; T Isse; Shibuya, I; K Kitamura; K Kangawa; H Matsuo; T Eto; Y Hattori; H Yamashita
PEPTIDES, 1999, Reviewed, No invitation

Inhibition of spontaneous inhibitory postsynaptic currents (IPSC) by noradrenaline in rat supraoptic neurons through presynaptic alpha(2)-adrenoceptors
YF Wang; Shibuya, I; N Kabashima; VS Setiadji; T Isse; Y Ueta; H Yamashita
BRAIN RESEARCH, Oct. 1998, Reviewed, No invitation

PTH-related peptide-like immunoreactivity in the median eminence, paraventricular and supraoptic nuclei in colchicine-treated rats
M Tokunaga; Y Ueta; T Isse; Y Hara; K Tanaka; S Yamamoto; N Kabashima; Shibuya, I; Y Hattori; H Yamashita
BRAIN RESEARCH, Nov. 1997, Reviewed, No invitation

Increase of urocortin-like immunoreactivity in the rat supraoptic nucleus after dehydration but not food deprivation
Y Hara; Y Ueta; T Isse; N Kabashima; Shibuya, I; Y Hattori; H Yamashita
NEUROSCIENCE LETTERS, Jun. 1997, Reviewed, No invitation

Increase of urocortin-like immunoreactivity in the rat hypothalamo-neurohypophysial system after salt loading and hypophysectomy
Y Hara; Y Ueta; T Isse; N Kabashima; Shibuya, I; Y Hattori; H Yamashita
NEUROSCIENCE LETTERS, May 1997, Reviewed, No invitation

Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat
Y Ueta; K Kitamura; T Isse; Shibuya, I; N Kabashima; S Yamamoto; K Kangawa; H Matsuo; T Eto; H Yamashita
NEUROSCIENCE LETTERS, Dec. 1995, Reviewed, No invitation

Changes of Working Responsibilities and Intentions of Industrial Physicians(Graduates of University of Occupational and Environmental Health, Japan)in a Comparison Between 2001, 2008 and 2015 Questionnaire Analyses
Hayato Nakamura, Toyohi Isse, Akinori Sakai
Journal of UOEH, Mar. 2017, Reviewed, No invitation

現代の若手整形外科医の育成　若手整形外科医の育成　労働衛生の観点から
川崎 展, 櫻澤 博文, 一瀬 豊日, 善家 雄吉, 中村 英一郎, 酒井 昭典
日本整形外科学会雑誌, Oct. 2022, Reviewed, No invitation

呼吸用保護具の定量的フィットテストから得られた知見　金属アーク溶接等作業に従事する労働者を対象とした調査から
辻 真弓, 安村 美子, 保利 一, 上野 晋, 一瀬 豊日, 後藤 元秀, 石塚 恒年, 長谷川 渉
Occupational Health Journal, Sep. 2022, Null, Null

【産業医の需要と供給をめぐる諸問題】産業医需要供給実態調査事業結果の概要
一瀬 豊日
産業医学ジャーナル, Jul. 2020, Not reviewed, Invited
Lead

【産業医の助言・指導・勧告をめぐって】産業医の助言・指導・勧告をめぐって　「産業医の事業所に対する助言、指導、勧告に関する実態調査報告書」から
一瀬 豊日
産業医学ジャーナル, May 2019, Not reviewed, Invited
Lead

産業医の需要と供給の諸条件と調整について　平成29年度産業医需要供給実態調査事業結果の概要
尾澤 英夫, 一瀬 豊日, 池上 和範, 産業医需要供給実態調査事業委員会
産業医学ジャーナル, Jul. 2018, Not reviewed, Invited
Lead

マクロ的に捉えた卒業生のキャリアと大学の役割
一瀬豊日
産業医科大学雑誌, Mar. 2023, Not reviewed, No invitation
Lead

本邦に必要とされる専属産業医数　事業所・企業統計調査(総務省統計局経済基本構造統計課)から推計
一瀬 豊日, 中村 早人, 戸倉 新樹
産業医科大学雑誌, Mar. 2010, Reviewed, Null

産業医業務に対する産業医科大学卒業生産業医の意識変化　2001年と2008年調査の比較
中村 早人, 一瀬 豊日, 松本 哲朗, 戸倉 新樹
産業医科大学雑誌, Sep. 2009, Reviewed, Null

International comparison of sensitizing chemical substances
村上朋絵, 小山倫浩, 一瀬豊日, 奈良井理恵, 金岡麻希, Pham Thi-Thu-Phuong, 川本俊弘
産業医科大学雑誌, Sep. 2007, Reviewed, No invitation

産業医需要供給実態調査から見えてきた諸課題
一瀬豊日
産業衛生学雑誌, Apr. 2023, Not reviewed, No invitation
Lead

わが国の産業医の平成14年から20年までの就退職数とその特徴
一瀬 豊日, 中村 早人, 蜂須賀 研二
産業衛生学雑誌, Sep. 2012, Reviewed, Null

ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice.
Chaudhry Kamaljit K, Samak Geetha, Shukla Pradeep K, Mir Hina, Gangwar Ruchika, Manda Bhargavi, Isse Toyohi, Kawamoto Toshihiro, Salaspuro Mikko, Kaihovaara Pertti, Dietrich Paula, Dragatsis Ioannis, Nagy Laura E, Rao Radha Krishna
Alcoholism, clinical and experimental research, Aug. 2015, Null, Null

Reduced bone formation in alcohol-induced osteopenia is associated with elevated p21 expression in bone marrow cells in aldehyde dehydrogenase 2-disrupted mice.
Shimizu Yuki, Sakai Akinori, Menuki Kunitaka, Mori Toshiharu, Isse Toyohi, Oyama Tsunehiro, Kawamoto Toshihiro, Nakamura Toshitaka
Bone, May 2011, Null, Null

Formation of acetaldehyde-derived DNA adducts due to alcohol exposure.
Yu Hsu-Sheng, Oyama Tsunehiro, Isse Toyohi, Kitagawa Kyoko, Pham Thi-Thu-Phuong, Tanaka Masayuki, Kawamoto Toshihiro
Chemico-biological interactions, Dec. 2010, Null, Null

Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory.
Tsuji Mayumi, Ishihara Yasuhiro, Isse Toyohi, Koriyama Chihaya, Yamamoto Megumi, Kakiuchi Noriaki, Yu Hsu-Sheng, Tanaka Masayuki, Tsuchiya Takuto, Ohta Masanori, Tanaka Rie, Kawamoto Toshihiro
Environmental health and preventive medicine, Jun. 2018, Reviewed, No invitation

Effect of Korean pear (Pyruspyrifolia cv. Shingo) juice on hangover severity following alcohol consumption.
Lee Ho-Sun, Isse Toyohi, Kawamoto Toshihiro, Baik Hyun Wook, Park Jong Y, Yang Mihi
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Aug. 2013, Reviewed, Null

日本の職場におけるHBVおよびHCV感染労働者(HBV- and HCV-Infected Workers in the Japanese Workplace)
Narai Rie, Oyama Tsunehiro, Ogawa Masanori, Yamaguchi Tetsunosuke, Kinaga Tsuyoshi, Murakami Tomoe, Isse Toyohi, Ozaki Shin-ichi, Yashima Yasunori, Okabayashi Ken, Ochiai Hideo, Yarita Keiichiro, Fujino Akihiro, Kawamoto Toshihiro
Journal of Occupational Health, Jan. 2007, Null, Null

Changes of Working Responsibilities and Intentions of Industrial Physicians (Graduates of University of Occupational and Environmental Health, Japan) in a Comparison Between 2001, 2008 and 2015 Questionnaire Analyses.
Nakamura Hayato, Isse Toyohi, Sakai Akinori
Journal of UOEH, 2017, Null, Null

Effects of LPS stimulation on the expression of prostaglandin carriers in the cells of the blood-brain and blood-cerebrospinal fluid barriers.
Kis Bela, Isse Toyohi, Snipes James A, Chen Lei, Yamashita Hiroshi, Ueta Yoichi, Busija David W
Journal of applied physiology (Bethesda, Md. : 1985), Apr. 2006, Reviewed, Null

The effect of mask fit test on the association between the concentration of metals in biological samples and the results of time-weighted average personal exposure: A study on Japanese male welders.
Tsuji Mayumi, Hori Hajime, Koriyama Chihaya, Tanaka Rie, Isse Toyohi, Ishihara Yasuhiro, Ishizuka Tsunetoshi, Hasegawa Wataru, Goto Motohide, Yatera Kazuhiro, Kunugita Naoki, Kuwamura Mami, Sakuragi Toshihide, Yasumura Yoshiko, Yamamoto Megumi, Ueno Susumu
Journal of occupational health, May 2023, Reviewed, No invitation

Associations between welding fume exposure and neurological function in Japanese male welders and non-welders.
Tsuji Mayumi, Koriyama Chihaya, Ishihara Yasuhiro, Isse Toyohi, Ishizuka Tsunetoshi, Hasegawa Wataru, Goto Motohide, Tanaka Rie, Kakiuchi Noriaki, Hori Hajime, Yatera Kazuhiro, Kunugita Naoki, Yamamoto Megumi, Sakuragi Toshihide, Yasumura Yoshiko, Kono Maori, Kuwamura Mami, Kitagawa Kyoko, Ueno Susumu
Journal of occupational health, Jan. 2023, Reviewed, Null

Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice.
Sun Aijun, Zou Yunzeng, Wang Ping, Xu Danling, Gong Hui, Wang Shijun, Qin Yingjie, Zhang Peng, Chen Yunqin, Harada Mutsuo, Isse Toyoshi, Kawamoto Toshihiro, Fan Huizhi, Yang Pengyuan, Akazawa Hiroshi, Nagai Toshio, Takano Hiroyuki, Ping Peipei, Komuro Issei, Ge Junbo
Journal of the American Heart Association, Sep. 2014, Reviewed, Null

Aldehyde dehydrogenase-2 deficiency aggravates cardiac dysfunction elicited by endoplasmic reticulum stress induction.
Liao Jianquan, Sun Aijun, Xie Yeqing, Isse Toyoshi, Kawamoto Toshihiro, Zou Yunzeng, Ge Junbo
Molecular medicine (Cambridge, Mass.), Jul. 2012, Null, Null

Retention among full-time occupational physicians in Japan.
Koike S, Isse T, Kawaguchi H, Ogawa M
Occupational medicine (Oxford, England), Apr. 2019, Reviewed, No invitation

Effects and action mechanisms of Korean pear (Pyrus pyrifolia cv. Shingo) on alcohol detoxification.
Lee Ho-Sun, Isse Toyoshi, Kawamoto Toshihiro, Woo Hyun-Su, Kim An Keun, Park Jong Y, Yang Mihi
Phytotherapy research : PTR, Nov. 2012, Null, Null

[Turnover of full-time occupational physicians in Japan in the period 2002-2008: a component model survey].
Isse Toyohi, Nakamura Hayato, Hachisuka Kenji
Sangyo eiseigaku zasshi = Journal of occupational health, 2012, Null, Null
Lead

Aldehyde dehydrogenase 2 gene targeting mouse lacking enzyme activity shows high acetaldehyde level in blood, brain, and liver after ethanol gavages.
Isse Toyohi, Matsuno Koji, Oyama Tsunehiro, Kitagawa Kyoko, Kawamoto Toshihiro
Alcoholism, clinical and experimental research, Nov. 2005, Null, Null

Pleomorphic carcinoma: report of a case with massive pleural effusion and asbestos particles.
Oyama Tsunehiro, Osaki Toshihiro, Isse Toyohi, Yashima Yasunori, Ozaki Shinichi, Nakata Shyouji, Uramoto Hidetaka, Sugaya Masakazu, Yasuda Manabu, Yamashita Toshihiro, Inoue Masaaki, Takenoyam Mitsuhiro, Hanagiri Takeshi, Sugio Kenji, Hamada Tetsuo, Kawamoto Toshihiro, Yasumoto Kosei
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, Apr. 2003, Null, Null

Evidence-based prevention (EBP): approach to lung cancer prevention based on cytochrome 1A1 and cytochrome 2E1 polymorphism.
Oyama Tsunehiro, Matsumoto Akiko, Isse Toyohi, Kim Yong-Dae, Ozaki Shinichi, Osaki Toshihiro, Sugio Kenji, Yasumoto Kosei, Kawamoto Toshihiro
Anticancer research, Null, Null

A case-case study comparing the usefulness of serum trace elements (Cu, Zn and Se) and tumor markers (CEA, SCC and SLX) in non-small cell lung cancer patients.
Oyama Tsunehiro, Kawamoto Toshihiro, Matsuno Koji, Osaki Toshihiro, Matsumoto Akiko, Isse Toyohi, Nakata Shyouzi, Ozaki Shinichi, Sugaya Masakazu, Yasuda Manabu, Yamashita Toshihiro, Takenoyama Mitsuhiro, Sugio Kenji, Yasumoto Kosei
Anticancer research, Null, Null

Application of tryptophan fluorescence to assess sensitizing potentials of chemicals.
Pham Thi-Thu-Phuong, Oyama Tsunehiro, Isse Toyohi, Kawamoto Toshihiro
Archives of environmental contamination and toxicology, Oct. 2009, Null, Null

Comparison of IgG against plastic resin in workers with and without chemical dermatitis.
Kawamoto Toshihiro, Tsuji Mayumi, Isse Toyohi
BMC public health, Sep. 2015, Null, Null

The effect of ethanol on the formation of N2-ethylidene-dG adducts in mice: implications for alcohol-related carcinogenicity of the oral cavity and esophagus.
Yu Hsu-Sheng, Oyama Tsunehiro, Matsuda Tomonari, Isse Toyohi, Yamaguchi Tetsunosuke, Tanaka Masayuki, Tsuji Mayumi, Kawamoto Toshihiro
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, May 2012, Null, Null

Disruption of aldehyde dehydrogenase 2 gene results in altered cortical bone structure and increased cortical bone mineral density in the femoral diaphysis of mice.
Tsuchiya Takuto, Sakai Akinori, Menuki Kunitaka, Mori Toshiharu, Takeuchi Yoshinori, Kanoh Shinkichi, Utsunomiya Hajime, Murai Teppei, Isse Toyohi, Kawamoto Toshihiro, Nakamura Toshitaka
Bone, Apr. 2013, Null, Null

Lung cancer andCYP1A1 orGSTM1 polymorphisms.
Oyama Tsunehiro, Kagawa Norio, Kim Yong-Dae, Matsumoto Akiko, Isse Toyohi, Kawamoto Toshihiro
Environmental health and preventive medicine, Jan. 2003, Null, Null

International comparison of criteria for evaluating sensitization of PRTR-designated chemical substances.
Murakami Tomoe, Oyama Tsunehiro, Isse Toyohi, Ogawa Masanori, Sugie Takuya, Kawamoto Toshihiro
Environmental health and preventive medicine, Mar. 2007, Null, Null

Evidence-based prevention (EBP): A review of cytochrome P450 expression in the bronchial epithelium and new approach to lung cancer prevention.
Oyama Tsunehiro, Isse Toyohi, Murakami Tomoe, Suzuki-Narai Rie, Ogawa Masanori, Yamaguchi Tetsunosuke, Kinaga Tsuyoshi, Yashima Yasunori, Ozaki Shinichi, Kim Yong-Dae, Kim Heon, Kawamoto Toshihiro
Environmental health and preventive medicine, May 2006, Null, Null

Bisphenol A levels in human urine.
Matsumoto Akiko, Kunugita Naoki, Kitagawa Kyoko, Isse Toyohi, Oyama Tsunehiro, Foureman Gary L, Morita Masatoshi, Kawamoto Toshihiro
Environmental health perspectives, Jan. 2003, Null, Null

Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene.
Kim Yong-Dae, Todoroki Hidekazu, Oyama Tsunehiro, Isse Toyohi, Matsumoto Akiko, Yamaguchi Tetsunosuke, Kim Heon, Uchiyama Iwao, Kawamoto Toshihiro
Environmental research, Mar. 2004, Null, Null

Effects of acetaldehyde inhalation in mitochondrial aldehyde dehydrogenase deficient mice (Aldh2-/-).
Oyama Tsunehiro, Nagayoshi Haruna, Matsuda Tomonari, Oka Megumi, Isse Toyohi, Yu Hsu-Sheng, Pham Thi-Thu-Phuong, Tanaka Masayuki, Kagawa Norio, Kaneko Kazuhiro, Kawamoto Toshihiro
Frontiers in bioscience (Elite edition), Jun. 2010, Null, Null

Hazardous environmental factors enhance impairment of liver function in HBV and HCV hepatitis.
Yashima Yasunori, Oyama Tsunehiro, Pham Thi Thu Phuong, Yamaguchi Tetunosuke, Narai Rie, Isse Toyohi, Uramoto Hidetaka, Sugio Kenji, Yasumoto Kosei, Kagawa Norio, Kawamoto Toshihiro
Frontiers in bioscience (Landmark edition), Jan. 2009, Null, Null

Expression of cytochrome P450 in tumor tissues and its association with cancer development.
Oyama Tsunehiro, Kagawa Norio, Kunugita Naoki, Kitagawa Kyoko, Ogawa Masanori, Yamaguchi Tetsunosuke, Suzuki Rie, Kinaga Tsuyoshi, Yashima Yasunori, Ozaki Shinichi, Isse Toyohi, Kim Yong-Dae, Kim Heon, Kawamoto Toshihiro
Frontiers in bioscience : a journal and virtual library, May 2004, Null, Null

Expression of cytochrome P450 in non-small cell lung cancer.
Oyama Tsunehiro, Sugio Kenji, Isse Toyohi, Matsumoto Akiko, Nose Naohiro, Uramoto Hidetaka, Nozoe Tadahiro, Morita Masaru, Kagawa Norio, Osaki Toshihiro, Muto Manabu, Yasumoto Kosei, Kawamoto Toshihiro
Frontiers in bioscience : a journal and virtual library, May 2008, Null, Null

Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis.
Oyama Tsunehiro, Sugio Kenji, Uramoto Hidetaka, Iwata Teruo, Onitsuka Takamitsu, Isse Toyohi, Nozoe Tadahiro, Kagawa Norio, Yasumoto Kosei, Kawamoto Toshihiro
Frontiers in bioscience : a journal and virtual library, May 2007, Null, Null

Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice.
Oyama Tsunehiro, Isse Toyohi, Ogawa Masanori, Muto Manabu, Uchiyama Iwao, Kawamoto Toshihiro
Frontiers in bioscience : a journal and virtual library, Jan. 2007, Null, Null

Smoking cessation program and CYP2A6 polymorphism.
Ozaki Shinichi, Oyama Tsunehiro, Isse Toyohi, Kagawa Norio, Uramoto Hidetaka, Sugio Kenji, Yasumoto Kosei, Kono Keizo, Kawamoto Toshihiro
Frontiers in bioscience : a journal and virtual library, Sep. 2006, Null, Null

Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism.
Oyama Tsunehiro, Isse Toyohi, Kagawa Norio, Kinaga Tsuyoshi, Kim Yong-Dae, Morita Masaru, Sugio Kenji, Weiner Henry, Yasumoto Kosei, Kawamoto Toshihiro
Frontiers in bioscience : a journal and virtual library, Jan. 2005, Null, Null

Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer.
Oyama Tsunehiro, Morita Masaru, Isse Toyohi, Kagawa Norio, Nakata Shyouzi, So Tetsuya, Mizukami Makiko, Ichiki Yoshinobu, Ono Kenji, Sugaya Masakazu, Uramoto Hidetaka, Yoshimatsu Takashi, Hanagiri Takeshi, Sugio Kenji, Kawamoto Toshihiro, Yasumoto Kosei
Frontiers in bioscience : a journal and virtual library, May 2005, Null, Null

Urinary 8-hydoxydeoxyguanosine (8-OHdG) and plasma malondialdehyde (MDA) levels in Aldh2 knock-out mice under acetaldehyde exposure.
Ogawa Masanori, Isse Toyohi, Oyama Tsunehiro, Kunugita Naoki, Yamaguchi Tetsunosuke, Kinaga Tsuyoshi, Narai Rie, Matsumoto Akiko, Kim Yong-Dae, Kim Heon, Uchiyama Iwao, Kawamoto Toshihiro
Industrial health, Jan. 2006, Null, Null

[University of Occupational and Environmental Health, Japan: 2013 alumni physician statistics].
Isse Toyohi, Nakamura Hayato, Hachisuka Kenji
Journal of UOEH, Oct. 2013, Null, Null
Lead

[Necessary number of dedicated industrial physicians in Japan: evaluated from the establishment and enterprise census].
Isse Toyohi, Nakamura Hayato, Tokura Yoshiki
Journal of UOEH, Mar. 2010, Null, Null

[Changes of working responsibilities and intentions of industrial physicians who are graduates of University of Occupational and Environmental Health, Japan, in 2001 and 2008 questionnaire analyses].
Nakamura Hayato, Isse Toyohi, Matsumoto Tetsuro, Tokura Yoshiki
Journal of UOEH, Sep. 2009, Null, Null

[International comparison of sensitizing chemical substances].
Murakami Tomoe, Oyma Tsunehiro, Isse Toyohi, Narai Rie, Kanaoka Maki, Pham Thi-Thu-Phuong, Kawamoto Toshihiro
Journal of UOEH, Sep. 2007, Null, Null

[Evidence based prevention (EBP): evidence-based approach to prevention of lung cancer by application of cytochrome 2E1 polymorphism].
Oyama Tsunehiro, Kawamoto Toshihiro, Matsumoto Akiko, Isse Toyohi, Ozaki Shinichi, Yasumoto Kosei
Journal of UOEH, Dec. 2002, Null, Null

Effects of lifestyle on urinary 1-hydroxypyrene concentration.
Kawamoto Toshihiro, Yang Mihi, Kim Yong-Dae, Kim Heon, Oyama Tsunehiro, Isse Toyohi, Matsuno Koji, Katoh Takahiko, Uchiyama Iwao
Journal of occupational health, May 2007, Null, Null

HBV- and HCV- infected workers in the Japanese workplace.
Narai Rie, Oyama Tsunehiro, Ogawa Masanori, Yamaguchi Tetsunosuke, Kinaga Tsuyoshi, Murakami Tomoe, Isse Toyohi, Ozaki Shin-Ichi, Yashima Yasunori, Okabayashi Ken, Ochiai Hideo, Yarita Keiichiro, Fujino Akihiro, Kawamoto Toshihiro
Journal of occupational health, Jan. 2007, Null, Null

Hemoglobin adducts as a marker of exposure to chemical substances, especially PRTR class I designated chemical substances.
Ogawa Masanori, Oyama Tsunehiro, Isse Toyohi, Yamaguchi Tetsunosuke, Murakami Tomoe, Endo Yoko, Kawamoto Toshihiro
Journal of occupational health, Sep. 2006, Null, Null

Increased frequencies of micronucleated reticulocytes and T-cell receptor mutation in Aldh2 knockout mice exposed to acetaldehyde.
Kunugita Naoki, Isse Toyohi, Oyama Tsunehiro, Kitagawa Kyoko, Ogawa Masanori, Yamaguchi Tetsunosuke, Kinaga Tsuyoshi, Kawamoto Toshihiro
The Journal of toxicological sciences, Feb. 2008, Null, Null

Paired acute inhalation test reveals that acetaldehyde toxicity is higher in aldehyde dehydrogenase 2 knockout mice than in wild-type mice.
Isse Toyohi, Oyama Tsunehiro, Matsuno Koji, Ogawa Masanori, Narai-Suzuki Rie, Yamaguchi Tetsunosuke, Murakami Tomoe, Kinaga Tsuyoshi, Uchiyama Iwao, Kawamoto Toshihiro
The Journal of toxicological sciences, Dec. 2005, Null, Null

Aldehyde dehydrogenase 2 activity affects symptoms produced by an intraperitoneal acetaldehyde injection, but not acetaldehyde lethality.
Isse Toyohi, Oyama Tsunehiro, Matsuno Koji, Uchiyama Iwao, Kawamoto Toshihiro
The Journal of toxicological sciences, Dec. 2005, Null, Null

Diminished alcohol preference in transgenic mice lacking aldehyde dehydrogenase activity.
Isse Toyohi, Oyama Tsunehiro, Kitagawa Kyoko, Matsuno Koji, Matsumoto Akiko, Yoshida Akira, Nakayama Keiko, Nakayama Kei-Ichi, Kawamoto Toshihiro
Pharmacogenetics, Nov. 2002, Null, Null

Methods and rationale for keeping records of hepatitis virus testing in Japanese workplaces.
Narai Rie, Oyama Tsunehiro, Isse Toyohi, Moriguchi Jiro, Yashima Yasunori, Fujino Akihiro, Horie Seichi, Kawamoto Toshihiro
Sangyo eiseigaku zasshi = Journal of occupational health, Jan. 2008, Null, Null

A comparison of covalent binding of ethanol metabolites to DNA according to Aldh2 genotype.
Ogawa Masanori, Oyama Tsunehiro, Isse Toyohi, Saito Koichi, Tomigahara Yoshitaka, Endo Yoko, Kawamoto Toshihiro
Toxicology letters, Jan. 2007, Null, Null

Characteristics of aldehyde dehydrogenase 2 (Aldh2) knockout mice.
Yu Hsu-Sheng, Oyama Tsunehiro, Isse Toyohi, Kitakawa Kyoko, Ogawa Masanori, Pham Thi-Thu-Phuong, Kawamoto Toshihiro
Toxicology mechanisms and methods, Nov. 2009, Null, Null

産業医需要供給実態調査事業報告書Ⅲ（ 地域調査・ボトルネック解消事業報告 ）
池上和範; 一瀬豊日; 伊津野信之; 井上真; 色川俊也; 大坪正剛; 尾澤英夫; 上村修治; 永田昌子; 森晃爾, Joint work
産業医需要供給実態調査事業委員会, Mar. 2025

産業医需要供給実態調査事業報告書Ⅱ(平成30 年度・令和元年度 地域調査報告)
安福慎一; 池上和範; 一瀬豊日; 井上真; 岩崎明夫; 尾澤英夫; 神村裕子; 小池創一; 清水英祐; 竹田透; 土肥誠太郎; 増田将史, Joint work
産業医需要供給実態調査事業委員会, Jun. 2022

産業医需要供給実態調査事業報告書 平成29年度
安福慎一; 池上和範; 一瀬豊日; 岩崎明夫; 及川桂; 尾澤英夫; 小池創一; 櫻井治彦; 竹田透; 増田将史; 松本吉郎, Joint work
産業医需要供給実態調査事業委員会, Feb. 2019

産業医の事業所に対する助言、指導、勧告に関する実態調査報告書
一瀬豊日, Single work
産業医科大学, Mar. 2018

Acetaldehyde Elimination Changes in Transgenic Mice Lacking Aldehyde Dehydrogenase 2 Activity. In Enzymology and Molecular Biology of Carbonyl Metabolism 12, edited by: Henry Weiner
Purdue University Press, Ashland OH USA, 2005, Not reviewed

Acetaldehyde Elimination Changes in Transgenic Mice Lacking Aldehyde Dehydrogenase 2 Activity. In Enzymology and Molecular Biology of Carbonyl Metabolism 12, edited by: Henry Weiner
Purdue University Press, Ashland OH USA, 2004, Not reviewed

環境化学物質の代謝とその周辺：オクチルフェノールエトキシレートおよびノニルフェノールエトキシレート
財団法人 日本公衆衛生協会, 2003, Not reviewed

環境化学物質の代謝とその周辺：ノニルフェノール
財団法人 日本公衆衛生協会, 2003, Not reviewed

環境化学物質の代謝とその周辺：オクチルフェノール
財団法人 日本公衆衛生協会, 2003, Not reviewed

労働衛生管理
社会医学事典, 2002, Not reviewed

平成29年度産業医需要供給実態調査事業報告書
安福 愼一, 一瀬 豊日, 池上 和範, 岩崎 明夫, 及川 桂, 尾澤 英夫, 小池 創一, 櫻井 治彦, 竹田 透, 土肥 誠太郎, 増田 将史, 松本 吉郎, Others
産業医科大学, Mar. 2018

安福愼一, 飯田和久, 池上和範, 一瀬豊日, 伊津野信之, 伊藤直人, 色川俊也, 井上真, 岩崎明夫, 及川桂, 大坪正剛, 尾澤英夫,神村裕子, 小池創一, 清水英佑, 竹田透, 土肥誠太郎, 福澤義行, 藤野善久 増田将史,森口次郎, Joint work
産業医科大学・産業医学振興財団, Jun. 2022