【Under review】 Neurological disorders and imbalance of metabolic homeostasis
Hirotaka Tao; Koichi Fujisawa
Dec. 2025
Lead, Corresponding

【Under review】Chaotic Chronic Inflammation and Tumorigenesis: Biomechanical Properties in Cross-Hierarchical Microenvironments
Hirotaka Tao
Dec. 2025
Lead, Corresponding

Tumor Development in Ulcerative Colitis: Perspectives From Biomechanical Characteristics.
Hirotaka Tao
Development, growth & differentiation, Dec. 2025, Reviewed
Lead, Corresponding

A thermodynamic perspective on mammalian neural crest ingression.
Clarissa C Pasiliao; Evan C Thomas; Theodora Yung; Min Zhu; Hirotaka Tao; Yu Sun; Sidhartha Goyal; Sevan Hopyan
Proceedings of the National Academy of Sciences of the United States of America, Sep. 2025, Reviewed

A fibronectin gradient remodels mixed-phase mesoderm.
Min Zhu; Bin Gu; Evan C Thomas; Yunyun Huang; Yun-Kyo Kim; Hirotaka Tao; Theodora M Yung; Xin Chen; Kaiwen Zhang; Elizabeth K Woolaver; Mikaela R Nevin; Xi Huang; Rudolph Winklbauer; Janet Rossant; Yu Sun; Sevan Hopyan
Science advances, Jul. 2024, Reviewed

Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo.
Kelli D Fenelon; Evan Thomas; Mohammad Samani; Min Zhu; Hirotaka Tao; Yu Sun; Helen McNeill; Sevan Hopyan
Biology open, Nov. 2022, Reviewed

Patterning the embryonic pulmonary mesenchyme.
Katharine Goodwin; Jacob M Jaslove; Hirotaka Tao; Min Zhu; Sevan Hopyan; Celeste M Nelson
iScience, Mar. 2022, Reviewed, No invitation

IRX3/5 regulate mitotic chromatid segregation and limb bud shape.
Hirotaka Tao; Jean-Philippe Lambert; Theodora M Yung; Min Zhu; Noah A Hahn; Danyi Li; Kimberly Lau; Kendra Sturgeon; Vijitha Puviindran; Xiaoyun Zhang; Wuming Gong; Xiao Xiao Chen; Gregory Anderson; Daniel J Garry; R Mark Henkelman; Yu Sun; Angelo Iulianella; Yasuhiko Kawakami; Anne-Claude Gingras; Chi-Chung Hui; Sevan Hopyan
Development (Cambridge, England), Oct. 2020, Reviewed
Lead

Spatial mapping of tissue properties in vivo reveals a 3D stiffness gradient in the mouse limb bud.
Min Zhu; Hirotaka Tao; Mohammad Samani; Mengxi Luo; Xian Wang; Sevan Hopyan; Yu Sun
Proceedings of the National Academy of Sciences of the United States of America, Mar. 2020, Reviewed

Magnetic Micromanipulation for In Vivo Measurement of Stiffness Heterogeneity and Anisotropy in the Mouse Mandibular Arch.
Min Zhu; Kaiwen Zhang; Hirotaka Tao; Sevan Hopyan; Yu Sun
Research (Washington, D.C.), 2020, Reviewed

Oscillatory cortical forces promote three dimensional cell intercalations that shape the murine mandibular arch.
Hirotaka Tao; Min Zhu; Kimberly Lau; Owen K W Whitley; Mohammad Samani; Xiao Xiao; Xiao Xiao Chen; Noah A Hahn; Weifan Liu; Megan Valencia; Min Wu; Xian Wang; Kelli D Fenelon; Clarissa C Pasiliao; Di Hu; Jinchun Wu; Shoshana Spring; James Ferguson; Edith P Karuna; R Mark Henkelman; Alexander Dunn; Huaxiong Huang; Hsin-Yi Henry Ho; Radhika Atit; Sidhartha Goyal; Yu Sun; Sevan Hopyan
Nature communications, Apr. 2019, Reviewed
Lead

Characterizing Inner Pressure and Stiffness of Trophoblast and Inner Cell Mass of Blastocysts.
Xian Wang; Zhuoran Zhang; Hirotaka Tao; Jun Liu; Sevan Hopyan; Yu Sun
Biophysical journal, Dec. 2018, Reviewed

The two domain hypothesis of limb prepattern and its relevance to congenital limb anomalies.
Hirotaka Tao; Yasuhiko Kawakami; Chi-Chung Hui; Sevan Hopyan
Wiley interdisciplinary reviews. Developmental biology, Jul. 2017, Reviewed
Lead

Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo.
Jun Wen; Hirotaka Tao; Kimberly Lau; Haijiao Liu; Craig A Simmons; Yu Sun; Sevan Hopyan
Biophysical journal, May 2017, Reviewed

Anisotropic stress orients remodelling of mammalian limb bud ectoderm.
Kimberly Lau; Hirotaka Tao; Haijiao Liu; Jun Wen; Kendra Sturgeon; Natalie Sorfazlian; Savo Lazic; Jeffrey T A Burrows; Michael D Wong; Danyi Li; Steven Deimling; Brian Ciruna; Ian Scott; Craig Simmons; R Mark Henkelman; Trevor Williams; Anna-Katerina Hadjantonakis; Rodrigo Fernandez-Gonzalez; Yu Sun; Sevan Hopyan
Nature cell biology, May 2015, Reviewed
Lead

PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders.
Lily Paemka; Vinit B Mahajan; Jessica M Skeie; Levi P Sowers; Salleh N Ehaideb; Pedro Gonzalez-Alegre; Toshikuni Sasaoka; Hirotaka Tao; Asuka Miyagi; Naoto Ueno; Keizo Takao; Tsuyoshi Miyakawa; Shu Wu; Benjamin W Darbro; Polly J Ferguson; Andrew A Pieper; Jeremiah K Britt; John A Wemmie; Danielle S Rudd; Thomas Wassink; Hatem El-Shanti; Heather C Mefford; Gemma L Carvill; J Robert Manak; Alexander G Bassuk
PloS one, 2013, Reviewed

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis.
Hirotaka Tao; Ken-ichi Inoue; Hiroshi Kiyonari; Alexander G Bassuk; Jeffrey D Axelrod; Hiroshi Sasaki; Shinichi Aizawa; Naoto Ueno
Developmental biology, Apr. 2012, Reviewed
Lead

Mutations in prickle orthologs cause seizures in flies, mice, and humans.
Hirotaka Tao; J Robert Manak; Levi Sowers; Xue Mei; Hiroshi Kiyonari; Takaya Abe; Nader S Dahdaleh; Tian Yang; Shu Wu; Shan Chen; Mark H Fox; Christina Gurnett; Thomas Montine; Thomas Bird; Lisa G Shaffer; Jill A Rosenfeld; Juliann McConnell; Suneeta Madan-Khetarpal; Elizabeth Berry-Kravis; Hilary Griesbach; Russell P Saneto; Matthew P Scott; Dragana Antic; Jordan Reed; Riley Boland; Salleh N Ehaideb; Hatem El-Shanti; Vinit B Mahajan; Polly J Ferguson; Jeffrey D Axelrod; Anna-Elina Lehesjoki; Bernd Fritzsch; Diane C Slusarski; John Wemmie; Naoto Ueno; Alexander G Bassuk
American journal of human genetics, Feb. 2011, Reviewed
Lead

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity.
Hirotaka Tao; Makoto Suzuki; Hiroshi Kiyonari; Takaya Abe; Toshikuni Sasaoka; Naoto Ueno
Proceedings of the National Academy of Sciences of the United States of America, Aug. 2009, Reviewed
Lead

Exogenous FGF10 can rescue an eye-open at birth phenotype of Fgf10-null mice by activating activin and TGFalpha-EGFR signaling.
Hirotaka Tao; Katsuhiko Ono; Hitomi Kurose; Sumihare Noji; Hideyo Ohuchi
Development, growth & differentiation, Jun. 2006, Reviewed
Lead

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development.
Hirotaka Tao; Miyuki Shimizu; Ryo Kusumoto; Katsuhiko Ono; Sumihare Noji; Hideyo Ohuchi
Development (Cambridge, England), Jul. 2005, Reviewed
Lead

Fibroblast growth factor 10 is required for proper development of the mouse whiskers.
Hideyo Ohuchi; Hirotaka Tao; Kazuyo Ohata; Nobuyuki Itoh; Shigeaki Kato; Sumihare Noji; Katsuhiko Ono
Biochemical and biophysical research communications, Mar. 2003, Reviewed

FGF10 is a mesenchymally derived stimulator for epidermal development in the chick embryonic skin.
Hirotaka Tao; Yasuko Yoshimoto; Hidefumi Yoshioka; Tsutomu Nohno; Sumihare Noji; Hideyo Ohuchi
Mechanisms of development, Aug. 2002, Reviewed
Lead

Cloning and expression of the chick p63 gene
Akihiro Yasue; Hirotaka Tao; Tsutomu Nohno; Keiji Moriyama; Sumihare Noji; Hideyo Ohuchi
Mechanisms of Development, 2001, Reviewed, No invitation
Lead

Asymmetric expression of antivin/lefty1 in the early chick embryo
Y Ishimaru; H Yoshioka; H Tao; B Thisse; C Thisse; CVE Wright; H Hamada; H Ohuchi; S Noji
MECHANISMS OF DEVELOPMENT, Jan. 2000, Reviewed, No invitation