2,5-Dimethylcelecoxib inhibits lung fibrosis in a mouse model of bleomycin-induced pulmonary fibrosis.
Toshiki Morimoto; Shin Ishikane; Masaki Arioka; Kohei Hashimoto; Kazunobu Igawa; Yasuyuki Higashi; Taisuke Tomonaga; Chinatsu Nishida; Kazuhiro Yatera; Fumi Takahashi-Yanaga
Respiratory investigation, May 2026, Reviewed
Last

Postoperative administration of 2,5-dimethylcelecoxib attenuates ischemia-reperfusion injury-induced cardiac dysfunction
Shin Ishikane; Takehiro Kishigami; Eigo Ikushima; Masaki Arioka; Kazunobu Igawa; Fumi Takahashi-Yanaga
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2026, Reviewed
Last

Celecoxib inhibits skin fibrosis via suppressing adipocyte progenitor-myofibroblast transdifferentiation by attenuating the YAP/TAZ signaling pathway.
Masaki Arioka; Hiroaki Matsunaga; Shin Ishikane; Kazuma Ito; Kohei Hashimoto; Yi Wang; Kazunobu Igawa; Fumi Takahashi-Yanaga
Life sciences, Oct. 2025, Reviewed
Last

Differentiation-inducing factor-1 inhibits EMT by proteasomal degradation of TAZ and YAP in cervical and colon cancer cell lines.
Masaki Arioka; Wang Yi; Kazunobu Igawa; Shin Ishikane; Fumi Takahashi-Yanaga
European journal of pharmacology, Dec. 2024, Reviewed
Last, Corresponding

Mammalian target of differentiation-inducing factor-1 is mitochondrial malate dehydrogenase for activation of AMP-activated protein kinase and induction of mitochondrial fission
Masaki Arioka; Koichi Miura; Ruzhe Han; Kazunobu Igawa; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
Life Sciences, Aug. 2024, Reviewed

2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction
Takehiro Kishigami; Shin Ishikane; Masaki Arioka; Kazunobu Igawa; Yosuke Nishimura; Fumi Takahashi-Yanaga
Journal of Pharmacological Sciences, Feb. 2024, Reviewed
Last

Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells.
Masaki Arioka; Fumi Seto-Tetsuo; Takeru Inoue; Koichi Miura; Shin Ishikane; Kazunobu Igawa; Katsuhiko Tomooka; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
Life sciences, Nov. 2023, Reviewed

Promising small molecule anti-fibrotic agents: Newly developed or repositioned drugs targeting myofibroblast transdifferentiation.
Shin Ishikane; Masaki Arioka; Fumi Takahashi-Yanaga
Biochemical pharmacology, Aug. 2023, Reviewed
Last, Corresponding

Increased risk of metastasis in patients with incidental use of renin-angiotensin system inhibitors: a retrospective analysis for multiple types of cancer based on electronic medical records
Akie Hirata; Shin Ishikane; Fumi Takahashi-Yanaga; Masaki Arioka; Tasuku Okui; Chinatsu Nojiri; Toshiyuki Sasaguri; Naoki Nakashima
Hypertension Research, Sep. 2022, Reviewed

2,5-Dimethylcelecoxib attenuates cardiac fibrosis caused by cryoinjury-induced myocardial infarction by suppressing the fibroblast-to-myofibroblast transformation via inhibition of the TGF-β signaling pathway
Eigo Ikushima; Shin Ishikane; Takehiro Kishigami; Hiroaki Matsunaga; Kazunobu Igawa; Katsuhiko Tomooka; Yosuke Nishimura; Fumi Takahashi-Yanaga
Biochemical Pharmacology, Mar. 2022, Reviewed
Last

Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells
Tomohiro Takiguchi; Fumi Takahashi-Yanaga; Shin Ishikane; Fumi Tetsuo; Hiroshi Hosoda; Masaki Arioka; Takanari Kitazono; Toshiyuki Sasaguri
European Journal of Pharmacology, Oct. 2021, Reviewed
Corresponding

DIF-1 inhibits growth and metastasis of triple-negative breast cancer through AMPK-mediated inhibition of the mTORC1-S6K signaling pathway
Fumi Seto-Tetsuo; Masaki Arioka; Koichi Miura; Takeru Inoue; Kazunobu Igawa; Katsuhiko Tomooka; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
Oncogene, Sep. 2021, Reviewed

Cardiac and renal protective effects of 2,5-dimethylcelecoxib in angiotensin II and high-salt-induced hypertension model mice.
Misaki Yamamoto; Fumi Takahashi-Yanaga; Masaki Arioka; Kazunobu Igawa; Katsuhiko Tomooka; Ken Yamaura; Toshiyuki Sasaguri
Journal of hypertension, May 2021, Reviewed
Corresponding

Differentiation-inducing factor-1 potentiates adipogenic differentiation and attenuates the osteogenic differentiation of bone marrow-derived mesenchymal stem cells
Shin Ishikane; Eigo Ikushima; Kazunobu Igawa; Katsuhiko Tomooka; Fumi Takahashi-Yanaga
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, Feb. 2021, Reviewed
Last

【COVID-19パンデミック下での薬学教育〜レジリエントな教育システム構築に向けて〜】医学・薬学・歯学教育におけるオンラインロールプレイを活用した実践的薬物治療教育の試み
柳田 俊彦; 中村 正帆; 吉川 雄朗; 石塚 洋一; 近藤 悠希; 高橋 富美; 藤田 朋恵; 有賀 純; 近藤 一直; 岡田 尚志郎; 竹内 弘; 岡村 信行; 谷内 一彦
薬学教育, 2021

Differentiation-inducing factor-1 suppresses cyclin D1-induced cell proliferation of MCF-7 breast cancer cells by inhibiting S6K-mediated signal transducer and activator of transcription 3 synthesis
Tetsuo, Fumi; Arioka, Masaki; Miura, Koichi; Kai, Misato; Kubo, Momoko; Igawa, Kazunobu; Tomooka, Katsuhiko; Takahashi-Yanaga, Fumi; Nishimura, Fusanori; Sasaguri, Toshiyuki
CANCER SCIENCE, Dec. 2019, Reviewed, No invitation

2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation
Shoji Morishige; Fumi Takahashi-Yanaga; Shin Ishikane; Masaki Arioka; Kazunobu Igawa; Akihiro Kuroo; Katsuhiko Tomooka; Akira Shiose; Toshiyuki Sasaguri
Biochemical Pharmacology, Oct. 2019, Reviewed, No invitation

Glycogen synthase kinase-3 inhibitor as a multi-targeting anti-rheumatoid drug.
Arioka M; Takahashi-Yanaga F
Biochemical pharmacology, Jul. 2019, Reviewed, No invitation

Influence of genetic polymorphisms and habitual caffeine intake on the changes in blood pressure, pulse rate, and calculation speed after caffeine intake: A prospective, double blind, randomized trial in healthy volunteers.
Yoshihara T; Zaitsu M; Shiraishi F; Arima H; Takahashi-Yanaga F; Arioka M; Kajioka S; Sasaguri T
Journal of pharmacological sciences, Mar. 2019, Reviewed, No invitation

Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells
Shin Ishikane; Hiroshi Hosoda; Takashi Nojiri; Takeshi Tokudome; Tetsuya Mizutani; Koichi Miura; Yoshiharu Akitake; Toru Kimura; Yoshitaka Imamichi; Shinya Kawabe; Yumiko Toyohira; Nobuyuki Yanagihara; Fumi Takahashi-Yanaga; Mikiya Miyazato; Kaoru Miyamoto; Kenji Kangawa
Biochemical Pharmacology, Aug. 2018, Reviewed, No invitation

The role of angiotensin II in cancer metastasis: Potential of renin-angiotensin system blockade as a treatment for cancer metastasis
Shin Ishikane; Fumi Takahashi-Yanaga
Biochemical Pharmacology, May 2018, Reviewed, No invitation
Last

Roles of glycogen synthase kinase-3 (GSK-3) in cardiac development and heart disease
Fumi Takahashi-Yanaga
Journal of UOEH, 2018, Reviewed, No invitation

Inorganic phosphate-induced impairment of osteoclast cell-cell fusion by the inhibition of AP-1-mediated DC-STAMP expression
Masaki Arioka; Fumi Takahashi-Yanaga; Narihito Tatsumoto; Toshiyuki Sasaguri
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Nov. 2017, Reviewed, No invitation

Anti-tumor effects of differentiation-inducing factor-1 in malignant melanoma: GSK-3-mediated inhibition of cell proliferation and GSK-3-independent suppression of cell migration and invasion
Masaki Arioka; Fumi Takahashi-Yanaga; Momoko Kubo; Kazunobu Igawa; Katsuhiko Tomooka; Toshiyuki Sasaguri
BIOCHEMICAL PHARMACOLOGY, Aug. 2017, Reviewed, No invitation

2,5-Dimethylcelecoxib prevents pressure-induced left ventricular remodeling through GSK-3 activation
Ai Fujita; Fumi Takahashi-Yanaga; Sachio Morimoto; Tatsuya Yoshihara; Masaki Arioka; Kazunobu Igawa; Katsuhiko Tomooka; Sumio Hoka; Toshiyuki Sasaguri
Hypertension Research, Feb. 2017, Reviewed, No invitation

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.
Issei Egashira; Fumi Takahashi-Yanaga; Risa Nishida; Masaki Arioka; Kazunobu Igawa; Katsuhiko Tomooka; Yoshimichi Nakatsu; Teruhisa Tsuzuki; Yusaku Nakabeppu; Takanari Kitazono; Toshiyuki Sasaguri
Cancer science, Jan. 2017, Reviewed, No invitation

Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes
Akihiro Nagano; Masaki Arioka; Fumi Takahashi-Yanaga; Etsuko Matsuzaki; Toshiyuki Sasaguri
JOURNAL OF PHARMACOLOGICAL SCIENCES, Jan. 2017, Reviewed, No invitation

Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts
Katsumasa Higashi; Etsuko Matsuzaki; Yoko Hashimoto; Fumi Takahashi-Yanaga; Aiko Takano; Hisashi Anan; Masato Hirata; Fusanori Nishimura
BONE, Dec. 2016, Reviewed, No invitation

Inhibition of GSK-3β increases trabecular bone volume but not cortical bone volume in adenine-induced uremic mice with severe hyperparathyroidism.
Tatsumoto N; Arioka M; Yamada S; Takahashi-Yanaga F; Tokumoto M; Tsuruya K; Kitazono T; Sasaguri T
Physiological reports, Nov. 2016, Reviewed, No invitation

Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells
Yoko Hashimoto; Mari Kobayashi; Etsuko Matsuzaki; Katsumasa Higashi; Fumi Takahashi-Yanaga; Aiko Takano; Masato Hirata; Fusanori Nishimura
CELL BIOLOGY INTERNATIONAL, Oct. 2016, Reviewed, No invitation

Inhibition of GSK-3 reduces prostaglandin E-2 production by decreasing the expression levels of COX-2 and mPGES-1 in monocyte/macrophage lineage cells
Toshihiro Noma; Fumi Takahashi-Yanaga; Masaki Arioka; Yoshihide Mori; Toshiyuki Sasaguri
BIOCHEMICAL PHARMACOLOGY, Sep. 2016, Reviewed, No invitation

GSK-3 beta heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy
Rasha M. S. M. Mohamed; Sachio Morimoto; Islam A. A. E. -H. Ibrahim; Dong-Yun Zhan; Cheng-Kun Du; Masaki Arioka; Tatsuya Yoshihara; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Jun. 2016, Reviewed, No invitation

Stage-dependent benefits and risks of pimobendan in mice with genetic dilated cardiomyopathy and progressive heart failure.
Nonaka M; Morimoto S; Murayama T; Kurebayashi N; Li L; Wang YY; Arioka M; Yoshihara T; Takahashi-Yanaga F; Sasaguri T
British journal of pharmacology, May 2015, Reviewed, No invitation

Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo.
Naoya Kubokura; Fumi Takahashi-Yanaga; Masaki Arioka; Tatsuya Yoshihara; Kazunobu Igawa; Katsuhiko Tomooka; Sachio Morimoto; Yoshimichi Nakatsu; Teruhisa Tsuzuki; Yusaku Nakabeppu; Takayuki Matsumoto; Takanari Kitazono; Toshiyuki Sasaguri
Journal of pharmacological sciences, Apr. 2015, Reviewed, No invitation

Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte
Yoko Hashimoto; Etsuko Matsuzaki; Katsumasa Higashi; Fumi Takahashi-Yanaga; Aiko Takano; Masato Hirata; Fusanori Nishimura
MOLECULAR AND CELLULAR BIOCHEMISTRY, Mar. 2015, Reviewed, No invitation

Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis
Masaki Arioka; Fumi Takahashi-Yanaga; Masanori Sasaki; Tatsuya Yoshihara; Sachio Morimoto; Masato Hirata; Yoshihide Mori; Toshiyuki Sasaguri
BIOCHEMICAL PHARMACOLOGY, Aug. 2014, Reviewed, No invitation

DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3β and expressions of cyclin D1 and TCF7L2 in cancer model mice.
Fumi Takahashi-Yanaga; Tatsuya Yoshihara; Kentaro Jingushi; Kazuhiro Igawa; Katsuhiko Tomooka; Yutaka Watanabe; Sachio Morimoto; Yoshimichi Nakatsu; Teruhisa Tsuzuki; Yusaku Nakabeppu; Toshiyuki Sasaguri
Biochemical pharmacology, Jun. 2014, Reviewed, No invitation

Acceleration of bone development and regeneration through the Wnt/β-catenin signaling pathway in mice heterozygously deficient for GSK-3β.
Arioka M; Takahashi-Yanaga F; Sasaki M; Yoshihara T; Morimoto S; Takashima A; Mori Y; Sasaguri T
Biochemical and biophysical research communications, Nov. 2013, Reviewed, No invitation

Sphingosine-1-phosphate promotes the nuclear translocation of beta-catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell lines
Etsuko Matsuzaki; Shunji Hiratsuka; Takafumi Hamachi; Fumi Takahashi-Yanaga; Yoko Hashimoto; Katsumasa Higashi; Mari Kobayashi; Takao Hirofuji; Masato Hirata; Katsumasa Maeda
BONE, Aug. 2013, Reviewed, No invitation

Differentiation-Inducing Factor-1 Suppresses the Expression of c-Myc in the Human Cancer Cell Lines
Kentaro Jingushi; Toshihisa Nakamura; Fumi Takahashi-Yanaga; Etsuko Matsuzaki; Yutaka Watanabe; Tatsuya Yoshihara; Sachio Morimoto; Toshiyuki Sasaguri
JOURNAL OF PHARMACOLOGICAL SCIENCES, Feb. 2013, Reviewed, No invitation

Role of brain serotonin dysfunction in the pathophysiology of congestive heart failure
Lei Li; Sachio Morimoto; Sachiko Take; Dong-Yun Zhan; Cheng-Kun Du; Yuan-Yuan Wang; Xue-Li Fan; Tatsuya Yoshihara; Fumi Takahashi-Yanaga; Toshihiko Katafuchi; Toshiyuki Sasaguri
Journal of Molecular and Cellular Cardiology, Dec. 2012, Reviewed, No invitation

Endogenous Cardiac Troponin T Modulates Ca2+-Mediated Smooth Muscle Contraction
Shunichi Kajioka; Fumi Takahashi-Yanaga; Nouval Shahab; Mitsuho Onimaru; Miho Matsuda; Ryosuke Takahashi; Haruhiko Asano; Hiromitsu Morita; Sachio Morimoto; Yoshikazu Yonemitsu; Maya Hayashi; Narihito Seki; Toshiuyki Sasaguri; Masato Hirata; Shinsuke Nakayama; Seiji Naito
SCIENTIFIC REPORTS, Dec. 2012, Reviewed, No invitation

Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle.
Shahab N; Kajioka S; Takahashi-Yanaga F; Onimaru M; Matsuda M; Seki N; Naito S
Neurourology and urodynamics, Apr. 2012, Reviewed, No invitation

DIF-1 inhibits the Wnt/beta-catenin signaling pathway by inhibiting TCF7L2 expression in colon cancer cell lines
Kentaro Jingushi; Fumi Takahashi-Yanaga; Tatsuya Yoshihara; Fumie Shiraishi; Yutaka Watanabe; Masato Hirata; Sachio Morimoto; Toshiyuki Sasaguri
BIOCHEMICAL PHARMACOLOGY, Jan. 2012, Reviewed, No invitation

Diphosphate regulation of adenosine triphosphate sensitive potassium channel in human bladder smooth muscle cells
Shunichi Kajioka; Nouval Shahab; Haruhiko Asano; Hiromitsu Morita; Megumi Sugihara; Fumi Takahashi-Yanaga; Tatsuya Yoshihara; Shinsuke Nakayama; Narihito Seki; Seiji Naito
Journal of Urology, Aug. 2011, Reviewed, No invitation

Differential effects of organic nitrates on arterial diameter among healthy Japanese participants with different mitochondrial aldehyde dehydrogenase 2 genotypes: randomised crossover trial.
Satoko Sakata; Tatsuya Yoshihara; Hisatomi Arima; Fumie Shiraishi; Hideyuki Oniki; Fumi Takahashi-Yanaga; Kiyoshi Matsumura; Toshiyuki Sasaguri
BMJ open, Jul. 2011

Celecoxib and 2,5-Dimethyl-Celecoxib Prevent Cardiac Remodeling Inhibiting Akt-Mediated Signal Transduction in an Inherited Dilated Cardiomyopathy Mouse Model
Xueli Fan; Fumi Takahashi-Yanaga; Sachio Morimoto; Dong-Yun Zhan; Kazunobu Igawa; Katsuhiko Tomooka; Toshiyuki Sasaguri
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Jul. 2011, Reviewed, No invitation

beta(1)-Adrenergic Receptor Gene Polymorphisms and the Acute Response to Atenolol in Healthy Young Japanese Subjects
Toshiyuki Sasaguri; Fumie Shiraishi; Tatsuya Yoshihara; Fumi Takahashi-Yanaga; Sachio Morimoto
JOURNAL OF PHARMACOLOGICAL SCIENCES, Apr. 2011, Reviewed, No invitation

Biological actions of green tea catechins on cardiac troponin C
Naoto Tadano; Cheng-Kun Du; Fumiaki Yumoto; Sachio Morimoto; Mika Ohta; Ming-Fang Xie; Koji Nagata; Dong-Yun Zhan; Qun-Wei Lu; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Masaru Tanokura; Iwao Ohtsuki; Toshiyuki Sasaguri
BRITISH JOURNAL OF PHARMACOLOGY, Nov. 2010, Reviewed, No invitation

Anti-angiogenic effects of differentiation-inducing factor-1 involving VEGFR-2 expression inhibition independent of the Wnt/beta-catenin signaling pathway
Tatsuya Yoshihara; Fumi Takahashi-Yanaga; Fumie Shiraishi; Sachio Morimoto; Yutaka Watanabe; Masato Hirata; Sumio Hoka; Toshiyuki Sasaguri
MOLECULAR CANCER, Sep. 2010, Reviewed, No invitation

Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy.
Wang YY; Morimoto S; Du CK; Lu QW; Zhan DY; Tsutsumi T; Ide T; Miwa Y; Takahashi-Yanaga F; Sasaguri T
Cardiovascular research, Sep. 2010, Reviewed, No invitation

Dictyostelium differentiation-inducing factor-1 binds to mitochondrial malate dehydrogenase and inhibits its activity.
Matsuda T; Takahashi-Yanaga F; Yoshihara T; Maenaka K; Watanabe Y; Miwa Y; Morimoto S; Kubohara Y; Hirata M; Sasaguri T
Journal of pharmacological sciences, 2010, Reviewed, No invitation

Therapeutic effect of beta-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation
Dong-Yun Zhan; Sachio Morimoto; Cheng-Kun Du; Yuan-Yuan Wang; Qun-Wei Lu; Atsushi Tanaka; Tomomi Ide; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
CARDIOVASCULAR RESEARCH, Oct. 2009, Reviewed, No invitation

The involvement of aldosterone in cyclic stretch-mediated activation of NADPH oxidase in vascular smooth muscle cells.
Ohmine T; Miwa Y; Takahashi-Yanaga F; Morimoto S; Maehara Y; Sasaguri T
Hypertension research : official journal of the Japanese Society of Hypertension, Aug. 2009, Reviewed, No invitation

Propyl gallate, a strong antioxidant, increases the Ca2+ sensitivity of cardiac myofilament.
Tadano N; Morimoto S; Takahashi-Yanaga F; Miwa Y; Ohtsuki I; Sasaguri T
Journal of pharmacological sciences, Mar. 2009, Reviewed, No invitation

Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs.
Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
Journal of pharmacological sciences, Feb. 2009

Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice.
Tanaka R; Miwa Y; Mou K; Tomikawa M; Eguchi N; Urade Y; Takahashi-Yanaga F; Morimoto S; Wake N; Sasaguri T
Biochemical and biophysical research communications, Jan. 2009, Reviewed, No invitation

Celecoxib-induced degradation of T-cell factors-1 and -4 in human colon cancer cells.
Takahashi-Yanaga F; Yoshihara T; Jingushi K; Miwa Y; Morimoto S; Hirata M; Sasaguri T
Biochemical and biophysical research communications, Dec. 2008, Reviewed, No invitation

Aryl hydrocarbon receptor mediates laminar fluid shear stress-induced CYP1A1 activation and cell cycle arrest in vascular endothelial cells
Zhiyi Han; Yoshikazu Miwa; Hiyo Obikane; Masako Mitsumata; Fumi Takahashi-Yanaga; Sachio Morimoto; Toshiyuki Sasaguri
CARDIOVASCULAR RESEARCH, Mar. 2008, Reviewed, No invitation

Association of serum lipocalin-type prostaglandin D synthase levels with subclinical atherosclerosis in untreated asymptomatic subjects
Yoshikazu Miwa; Hiroshi Oda; Yasuhiko Shiina; Kentaro Shikata; Motoo Tsushima; Satomi Nakano; Taro Maruyama; Shingo Kyotani; Naomi Eguchi; Yoshihiro Urade; Fumi Takahashi-Yanaga; Sachio Morimoto; Toshiyuki Sasaguri
Hypertension Research, 2008, Reviewed, No invitation

Association between arterial stiffness and cerebral white matter lesions in community-dwelling elderly subjects
Takahiro Ohmine; Yoshikazu Miwa; Hiroshi Yao; Takefumi Yuzuriha; Yuki Takashima; Akira Uchino; Fumi Takahashi-Yanaga; Sachio Morimoto; Yoshihiko Maehara; Toshiyuki Sasaguri
Hypertension Research, Jan. 2008, Reviewed, No invitation

Oxaliplatin induces mitotic catastrophe and apoptosis in esophageal cancer cells.
Ngan CY; Yamamoto H; Takagi A; Fujie Y; Takemasa I; Ikeda M; Takahashi-Yanaga F; Sasaguri T; Sekimoto M; Matsuura N; Monden M
Cancer science, Jan. 2008, Reviewed, No invitation

Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation
Cheng-Kun Du; Sachio Morimoto; Kiyomasa Nishii; Reiko Minakami; Mika Ohta; Naoto Tadano; Qun-Wei Lu; Yuan-Yuan Wang; Dong-Yun Zhan; Misato Mochizuki; Satomi Kita; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Takahiro Iwamoto; Iwao Ohtsuki; Toshiyuki Sasaguri
CIRCULATION RESEARCH, Jul. 2007, Reviewed, No invitation

Celecoxib induces apoptosis by inhibiting the expression of survivin in HeLa cells.
Fukada K; Takahashi-Yanaga F; Sakoguchi-Okada N; Shiraishi F; Miwa Y; Morimoto S; Sasaguri T
Biochemical and biophysical research communications, Jun. 2007, Reviewed, No invitation

Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells.
Sakoguchi-Okada N; Takahashi-Yanaga F; Fukada K; Shiraishi F; Taba Y; Miwa Y; Morimoto S; Iida M; Sasaguri T
Biochemical pharmacology, May 2007, Reviewed, No invitation

[Wnt/beta-catenin signaling pathway and drug discovery].
Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
Fukuoka igaku zasshi = Hukuoka acta medica, Apr. 2007

Prediction of recurrence after laparoscopic fundoplication for erosive reflux esophagitis based on anatomy-function-pathology (AFP) classification.
N Omura; H Kashiwagi; F Yano; K Tsuboi; Y Ishibashi; N Kawasaki; Y Suzuki; N Mitsumori; M Urashima; K Yanaga
Surgical endoscopy, Mar. 2007

Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells.
Takahashi-Yanaga F; Mori J; Matsuzaki E; Watanabe Y; Hirata M; Miwa Y; Morimoto S; Sasaguri T
The Journal of biological chemistry, Dec. 2006, Reviewed, No invitation

Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines.
Matsuzaki E; Takahashi-Yanaga F; Miwa Y; Hirata M; Watanabe Y; Sato N; Morimoto S; Hirofuji T; Maeda K; Sasaguri T
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Aug. 2006, Reviewed, No invitation

Differentiation-inducing factor-1 suppresses gene expression of cyclin D1 in tumor cells.
Yasmin T; Takahashi-Yanaga F; Mori J; Miwa Y; Hirata M; Watanabe Y; Morimoto S; Sasaguri T
Biochemical and biophysical research communications, Dec. 2005, Reviewed, No invitation

Drastic Ca2+ sensitization of myofilament associated with a small structural change in troponin I in inherited restrictive cardiomyopathy.
Yumoto F; Lu QW; Morimoto S; Tanaka H; Kono N; Nagata K; Ojima T; Takahashi-Yanaga F; Miwa Y; Sasaguri T; Nishita K; Tanokura M; Ohtsuki I
Biochemical and biophysical research communications, Dec. 2005, Reviewed, No invitation

Differentiation-inducing factor-1 induces cyclin D1 degradation through the phosphorylation of Thr286 in squamous cell carcinoma.
Mori J; Takahashi-Yanaga F; Miwa Y; Watanabe Y; Hirata M; Morimoto S; Shirasuna K; Sasaguri T
Experimental cell research, Nov. 2005, Reviewed, No invitation

Activator protein-1 mediates shear stress-induced prostaglandin D synthase gene expression in vascular endothelial cells
Miyagi M; Miwa Y; Takahashi-Yanaga F; Morimoto S; Sasaguri T
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005, Reviewed, No invitation

SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure.
Tadano N; Morimoto S; Yoshimura A; Miura M; Yoshioka K; Sakato M; Ohtsuki I; Miwa Y; Takahashi-Yanaga F; Sasaguri T
Journal of pharmacological sciences, Jan. 2005, Reviewed, No invitation

Effects of U-37883A on intracellular Ca 2+-activated large-conductance K + channels in pig proximal urethral myocytes
Noriyoshi Teramoto; Manami Aishima; Hai-Lei Zhu; Toshihisa Tomoda; Takakazu Yunoki; Fumi Takahashi-Yanaga; Alison F. Brading; Yushi Ito
European Journal of Pharmacology, Dec. 2004, Reviewed, No invitation

PKC412 induces apoptosis through a caspase-dependent mechanism in human keloid-derived fibroblasts
A Nakazono-Kusaba; F Takahashi-Yanaga; Y Miwa; S Morimoto; M Furue; T Sasaguri
EUROPEAN JOURNAL OF PHARMACOLOGY, Aug. 2004, Reviewed, No invitation

Involvement of clusterin in 15-deoxy-delta12,14-prostaglandin J2-induced vascular smooth muscle cell differentiation.
Miwa Y; Takahashi-Yanaga F; Morimoto S; Sasaguri T
Biochemical and biophysical research communications, Jun. 2004, Reviewed, No invitation

Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts.
Takahashi-Yanaga F; Shiraishi F; Hirata M; Miwa Y; Morimoto S; Sasaguri T
Biochemical and biophysical research communications, Apr. 2004, Reviewed, No invitation

Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
Lu QW; Morimoto S; Harada K; Du CK; Takahashi-Yanaga F; Miwa Y; Sasaguri T; Ohtsuki I
Journal of molecular and cellular cardiology, Dec. 2003, Reviewed, No invitation

15-Deoxy-Delta(12,14)-prostaglandin J(2) and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells
Y Taba; M Miyagi; Y Miwa; H Inoue; F Takahashi-Yanaga; S Morimoto; T Sasaguri
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Jul. 2003, Reviewed, No invitation

15_デオキシ_Δ^12,14_プロスタグランジンJ_2による血管平滑筋細胞の再分化誘導
三輸 宜一; 田場 洋二; 宮城 めぐみ; 高橋 富美; 森本 幸生; 笹栗 俊之
臨床薬理, Mar. 2003

Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells
Takayoshi Maiguma; Koji Fujisaki; Yoshinori Itoh; Kazutaka Makino; Daisuke Teshima; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri; Ryozo Oishi
Naunyn-Schmiedeberg's Archives of Pharmacology, Mar. 2003, Reviewed, No invitation

Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3beta and degrades cyclin D1 in mammalian cells.
Takahashi-Yanaga F; Taba Y; Miwa Y; Kubohara Y; Watanabe Y; Hirata M; Morimoto S; Sasaguri T
The Journal of biological chemistry, Mar. 2003, Reviewed, No invitation

Several aspects of calcium regulator mechanisms linked to troponin
Ohtsuki, I; S Morimoto; F Takahashi-Yanaga
MOLECULAR AND CELLULAR ASPECTS OF MUSCLE CONTRACTION, 2003, Reviewed, No invitation

Caspase-3-mediated α-smooth muscle actin cleavage during staurosporine-induced myofibroblast apoptosis
Ayako Nakazono; Fumi Takahashi-Yanaga; Masutaka Furue; Toshiyuki Sasaguri
Folia Pharmacologica Japonica, 2002, Reviewed, No invitation

Double blind study of the effect of caffeine on the mental calculation
F. Shiraishi; F. Takahashi; T. Goto; K. Harada; A. Kusaba; S. Morimoto
Fukuoka Acta Medica, 2000, Reviewed, No invitation

Erratum: Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils (Journal of Biochemistry (2000) 127:3 (355-357))
Takahashi-Yanaga F; Morimoto S; Ohtsuki I
Journal of Biochemistry, 2000, Reviewed, No invitation

Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy.
H Nakaura; S Morimoto; F Yanaga; M Nakata; H Nishi; T Imaizumi; I Ohtsuki
The American journal of physiology, Aug. 1999, Reviewed, No invitation

Studies on the endothelin-1-induced contraction of rat granulation tissue pouch mediated by myofibroblasts.
T Goto; F Yanaga; I Ohtsuki
Biochimica et biophysica acta, Oct. 1998

Effect of caffeine on the mental calculation.
N Suenaga; T Inamitsu; M Hatakenaka; F Yanaga; F Shiraishi
Fukuoka igaku zasshi = Hukuoka acta medica, Feb. 1997

Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor.
F Yanaga; A Poole; J Asselin; R Blake; G L Schieven; E A Clark; C L Law; S P Watson
The Biochemical journal, Oct. 1995

Phenylarsine oxide inhibits tyrosine phosphorylation of phospholipase C gamma 2 in human platelets and phospholipase C gamma 1 in NIH-3T3 fibroblasts.
F Yanaga; J Asselin; G L Schieven; S P Watson
FEBS letters, Jul. 1995

Ceramide does not mediate the effect of tumour necrosis factor alpha on superoxide generation in human neutrophils.
F Yanaga; S P Watson
The Biochemical journal, Mar. 1994

Synergism between muramyl dipeptide and lipopolysaccharide in the inhibition of glycosaminoglycan synthesis in cultured rat costal chondrocytes.
T Ikebe; M Hirata; F Yanaga; T Koga
Annals of the rheumatic diseases, Jan. 1993

Tumor necrosis factor alpha stimulates sphingomyelinase through the 55 kDa receptor in HL-60 cells.
F Yanaga; S P Watson
FEBS letters, Dec. 1992

Signal transduction by tumor necrosis factor alpha is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line, MC3T3-E1.
F Yanaga; M Abe; T Koga; M Hirata
The Journal of biological chemistry, Mar. 1992

Evidence for coupling of bradykinin receptors to a guanine-nucleotide binding protein to stimulate arachidonate liberation in the osteoblast-like cell line, MC3T3-E1.
F Yanaga; M Hirata; T Koga
Biochimica et biophysica acta, Sep. 1991

Synthetic inositol 1,3,4,5-tetrakisphosphate analogues.
M Hirata; Y Kimura; T Ishimatsu; F Yanaga; T Shuto; T Sasaguri; T Koga; Y Watanabe; S Ozaki
The Biochemical journal, Jun. 1991

Catabolic effects of muramyl dipeptide on rabbit chondrocytes.
T Ikebe; H Iribe; M Hirata; F Yanaga; T Koga
Arthritis and rheumatism, Dec. 1990

Stereospecific recognition of inositol 1,4,5-trisphosphate analogs by the phosphatase, kinase, and binding proteins.
M Hirata; F Yanaga; T Koga; T Ogasawara; Y Watanabe; S Ozaki
The Journal of biological chemistry, May 1990

Inositol 1,4,5-trisphosphate affinity chromatography.
M Hirata; Y Watanabe; T Ishimatsu; F Yanaga; T Koga; S Ozaki
Biochemical and biophysical research communications, Apr. 1990

蛋白尿改善を目指したイオンチャネル阻害剤の開発と評価
坂口怜子, 松田由宗, 岡田亮, 石兼真, 高橋富美, 片渕瑛介, 中山敏幸, 眞田賢哉 上田陽一, 木原隆典, 永田龍, 森誠之
Journal of UOEH, Mar. 2024, Reviewed, Null

DIF-1は循環腫瘍細胞の血管壁への接着を抑制することで抗転移効果を発揮する(DIF-1 exerted anti-metastatic effects via suppressing circulating tumor cell adhesion to blood vessels)
有岡 将基, 笹栗 俊之, 石兼 真, 高橋 富美
日本癌学会総会記事, Sep. 2022, Reviewed, Null
Corresponding

ジメチルセレコキシブの心筋障害後の線維化におけるマクロファージへの影響
岸上 赳大, 石兼 真, 西村 陽介, 高橋 富美
日本胸部外科学会定期学術集会, Oct. 2022, Not reviewed, No invitation
Corresponding

虚血再灌流障害に伴う心臓リモデリングに対する2,5-ジメチルセレコキシブの抑制効果
石兼 真, 岸上 赳大, 有岡 将基, 高橋 富美
産業医科大学雑誌, Mar. 2023, Null, Null

心臓の発達と病態におけるグリコーゲン合成酵素キナーゼ-3(GSK-3)の役割(Roles of Glycogen Synthase Kinase-3(CSK-3) in Cardiac Development and Heart Disease)
高橋 富美
産業医科大学雑誌, Jun. 2018, Null, Null
Lead

臨床に役立つ基礎薬理学の用語解説(第25回)　分子標的薬
高橋 富美
臨床精神薬理, Nov. 2021, Null, Null
Lead

セレコキシブはWnt標的遺伝子の発現を抑制することにより骨芽細胞の分化を阻害する
高橋 富美, 有岡 将基, 松崎 英津子, 笹栗 俊之
臨床薬理, Nov. 2017, Null, Null
Lead, Corresponding

昇圧ペプチドangiotensin IIによる血管内皮細胞を介した血行性癌転移増悪機構の解明
石兼 真, 細田 洋司, 野尻 崇, 徳留 健, 水谷 哲也, 豊平 由美子, 宮里 幹也, 宮本 薫, 寒川 賢治, 高橋 富美
臨床薬理, Nov. 2017, Null, Null
Last

アトルバスタチンの硝酸薬投与後血管内皮機能改善効果に及ぼすALDH2*2の影響
吉原 達也, 白源 正成, 白石 富美恵, 有馬 久富, 内丸 比奈子, 松木 俊二, 高橋 富美, 入江 伸, 笹栗 俊之
臨床薬理の進歩, Jun. 2016, Reviewed, Null

【COVID-19パンデミック下での薬学教育〜レジリエントな教育システム構築に向けて〜】医学・薬学・歯学教育におけるオンラインロールプレイを活用した実践的薬物治療教育の試み
柳田 俊彦, 中村 正帆, 吉川 雄朗, 石塚 洋一, 近藤 悠希, 高橋 富美, 藤田 朋恵, 有賀 純, 近藤 一直, 岡田 尚志郎, 竹内 弘, 岡村 信行, 谷内 一彦
薬学教育, 2021, Null, Null

GSK-3β heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy.
Mohamed Rasha M S M, Morimoto Sachio, Ibrahim Islam A A E-H, Zhan Dong-Yun, Du Cheng-Kun, Arioka Masaki, Yoshihara Tatsuya, Takahashi-Yanaga Fumi, Sasaguri Toshiyuki
American journal of physiology. Heart and circulatory physiology, Jun. 2016, Null, Null

Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells
Shin Ishikane, Hiroshi Hosoda, Takashi Nojiri, Takeshi Tokudome, Tetsuya Mizutani, Koichi Miura, Yoshiharu Akitake, Toru Kimura, Yoshitaka Imamichi, Shinya Kawabe, Yumiko Toyohira, Nobuyuki Yanagihara, Fumi Takahashi–Yanaga, Mikiya Miyazato, Kaoru Miyamoto, Kenji Kangawa
Biochemical Pharmacology, Apr. 2018, Reviewed, No invitation

The role of angiotensin II in cancer metastasis: Potential of renin-angiotensin system blockade as a treatment for cancer metastasis.
Shin Ishikane, Fumi Takahashi-Yanaga.
Biochemical Pharmacology, Mar. 2018, Reviewed, No invitation
Last

Inorganic phosphate-induced impairment of osteoclast cell-cell fusion by the inhibition of AP-1-mediated DC-STAMP expression.
Arioka Masaki, Takahashi-Yanaga Fumi, Tatsumoto Narihito, Sasaguri Toshiyuki
Biochemical and biophysical research communications, Nov. 2017, Null, Null

Promising small molecule anti-fibrotic agents: Newly developed or repositioned drugs targeting myofibroblast transdifferentiation.
石兼真, 有岡将基, 高橋富美
Biochemical pharmacology, Aug. 2023, Reviewed, Null
Last, Corresponding

2,5-Dimethylcelecoxib attenuates cardiac fibrosis caused by cryoinjury-induced myocardial infarction by suppressing the fibroblast-to-myofibroblast transformation via inhibition of the TGF-β signaling pathway.
Ikushima Eigo, Ishikane Shin, Kishigami Takehiro, Matsunaga Hiroaki, Igawa Kazunobu, Tomooka Katsuhiko, Nishimura Yosuke, Takahashi-Yanaga Fumi
Biochemical pharmacology, Mar. 2022, Reviewed, No invitation
Last, Corresponding

2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation.
Morishige Shoji, Takahashi-Yanaga Fumi, Ishikane Shin, Arioka Masaki, Igawa Kazunobu, Kuroo Akihiro, Tomooka Katsuhiko, Shiose Akira, Sasaguri Toshiyuki
Biochemical pharmacology, Jun. 2019, Reviewed, Null
Corresponding

Glycogen synthase kinase-3 inhibitor as a multi-targeting anti-rheumatoid drug.
Arioka Masaki, Takahashi-Yanaga Fumi
Biochemical pharmacology, Feb. 2019, Reviewed, Null

Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells.
Ishikane Shin, Hosoda Hiroshi, Nojiri Takashi, Tokudome Takeshi, Mizutani Tetsuya, Miura Koichi, Akitake Yoshiharu, Kimura Toru, Imamichi Yoshitaka, Kawabe Shinya, Toyohira Yumiko, Yanagihara Nobuyuki, Takahashi-Yanaga Fumi, Miyazato Mikiya, Miyamoto Kaoru, Kangawa Kenji
Biochemical pharmacology, Aug. 2018, Reviewed, Null

Anti-tumor effects of differentiation-inducing factor-1 in malignant melanoma: GSK-3-mediated inhibition of cell proliferation and GSK-3-independent suppression of cell migration and invasion.
Arioka Masaki, Takahashi-Yanaga Fumi, Kubo Momoko, Igawa Kazunobu, Tomooka Katsuhiko, Sasaguri Toshiyuki
Biochemical pharmacology, May 2017, Reviewed, Null
Corresponding

Inhibition of GSK-3 reduces prostaglandin E2 production by decreasing the expression levels of COX-2 and mPGES-1 in monocyte/macrophage lineage cells.
Noma Toshihiro, Takahashi-Yanaga Fumi, Arioka Masaki, Mori Yoshihide, Sasaguri Toshiyuki
Biochemical pharmacology, Sep. 2016, Reviewed, Null

Differentiation-inducing factor-1 potentiates adipogenic differentiation and attenuates the osteogenic differentiation of bone marrow-derived mesenchymal stem cells.
Ishikane Shin, Ikushima Eigo, Igawa Kazunobu, Tomooka Katsuhiko, Takahashi-Yanaga Fumi
Biochimica et biophysica acta. Molecular cell research, Feb. 2021, Reviewed, No invitation
Last

Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts.
Higashi Katsumasa, Matsuzaki Etsuko, Hashimoto Yoko, Takahashi-Yanaga Fumi, Takano Aiko, Anan Hisashi, Hirata Masato, Nishimura Fusanori
Bone, Dec. 2016, Reviewed, Null

Differentiation-inducing factor-1 suppresses cyclin D1-induced cell proliferation of MCF-7 breast cancer cells by inhibiting S6K-mediated signal transducer and activator of transcription 3 synthesis.
Tetsuo Fumi, Arioka Masaki, Miura Koichi, Kai Misato, Kubo Momoko, Igawa Kazunobu, Tomooka Katsuhiko, Takahashi-Yanaga Fumi, Nishimura Fusanori, Sasaguri Toshiyuki
Cancer science, Dec. 2019, Reviewed, Null

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.
Egashira Issei, Takahashi-Yanaga Fumi, Nishida Risa, Arioka Masaki, Igawa Kazunobu, Tomooka Katsuhiko, Nakatsu Yoshimichi, Tsuzuki Teruhisa, Nakabeppu Yusaku, Kitazono Takanari, Sasaguri Toshiyuki
Cancer science, Jan. 2017, Reviewed, Null

Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells.
Hashimoto Yoko, Kobayashi Mari, Matsuzaki Etsuko, Higashi Katsumasa, Takahashi-Yanaga Fumi, Takano Aiko, Hirata Masato, Nishimura Fusanori
Cell biology international, Oct. 2016, Reviewed, Null

Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells.
Takiguchi Tomohiro, Takahashi-Yanaga Fumi, Ishikane Shin, Tetsuo Fumi, Hosoda Hiroshi, Arioka Masaki, Kitazono Takanari, Sasaguri Toshiyuki
European journal of pharmacology, Oct. 2021, Reviewed, No invitation
Corresponding

Increased risk of metastasis in patients with incidental use of renin-angiotensin system inhibitors: a retrospective analysis for multiple types of cancer based on electronic medical records.
Hirata Akie, Ishikane Shin, Takahashi-Yanaga Fumi, Arioka Masaki, Okui Tasuku, Nojiri Chinatsu, Sasaguri Toshiyuki, Nakashima Naoki
Hypertension research : official journal of the Japanese Society of Hypertension, Dec. 2022, Reviewed, Null

2,5-Dimethylcelecoxib prevents pressure-induced left ventricular remodeling through GSK-3 activation.
Fujita Ai, Takahashi-Yanaga Fumi, Morimoto Sachio, Yoshihara Tatsuya, Arioka Masaki, Igawa Kazunobu, Tomooka Katsuhiko, Hoka Sumio, Sasaguri Toshiyuki
Hypertension research : official journal of the Japanese Society of Hypertension, Feb. 2017, Reviewed, Null

Cardiac and renal protective effects of 2,5-dimethylcelecoxib in angiotensin II and high-salt-induced hypertension model mice.
Yamamoto M, Takahashi-Yanaga F, Arioka M, Igawa K, Tomooka K, Yamaura K, Sasaguri T.
Journal of Hypertension Research, May 2021, Reviewed, No invitation
Corresponding

Roles of Glycogen Synthase Kinase-3 (GSK-3) in Cardiac Development and Heart Disease.
Takahashi-Yanaga Fumi
Journal of UOEH, Jun. 2018, Reviewed, No invitation
Lead

Cardiac and renal protective effects of 2,5-dimethylcelecoxib in angiotensin II and high-salt-induced hypertension model mice.
Yamamoto Misaki, Takahashi-Yanaga Fumi, Arioka Masaki, Igawa Kazunobu, Tomooka Katsuhiko, Yamaura Ken, Sasaguri Toshiyuki
Journal of hypertension, Nov. 2020, Reviewed, Null
Corresponding

2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction.
Kishigami Takehiro, Ishikane Shin, Arioka Masaki, Igawa Kazunobu, Nishimura Yosuke, Takahashi-Yanaga Fumi
Journal of pharmacological sciences, Feb. 2024, Reviewed, No invitation
Last

Influence of genetic polymorphisms and habitual caffeine intake on the changes in blood pressure, pulse rate, and calculation speed after caffeine intake: A prospective, double blind, randomized trial in healthy volunteers.
Yoshihara Tatsuya, Zaitsu Masayoshi, Shiraishi Fumie, Arima Hisatomi, Takahashi-Yanaga Fumi, Arioka Masaki, Kajioka Shunichi, Sasaguri Toshiyuki
Journal of pharmacological sciences, Mar. 2019, Reviewed, Null
Corresponding

Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes.
Nagano Akihiro, Arioka Masaki, Takahashi-Yanaga Fumi, Matsuzaki Etsuko, Sasaguri Toshiyuki
Journal of pharmacological sciences, Jan. 2017, Reviewed, Null

Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells.
Arioka Masaki, Seto-Tetsuo Fumi, Inoue Takeru, Miura Koichi, Ishikane Shin, Igawa Kazunobu, Tomooka Katsuhiko, Takahashi-Yanaga Fumi, Sasaguri Toshiyuki
Life sciences, Dec. 2023, Reviewed, Null

DIF-1 inhibits growth and metastasis of triple-negative breast cancer through AMPK-mediated inhibition of the mTORC1-S6K signaling pathway.
Seto-Tetsuo Fumi, Arioka Masaki, Miura Koichi, Inoue Takeru, Igawa Kazunobu, Tomooka Katsuhiko, Takahashi-Yanaga Fumi, Sasaguri Toshiyuki
Oncogene, Sep. 2021, Reviewed, Null

Inhibition of GSK-3β increases trabecular bone volume but not cortical bone volume in adenine-induced uremic mice with severe hyperparathyroidism.
Tatsumoto Narihito, Arioka Masaki, Yamada Shunsuke, Takahashi-Yanaga Fumi, Tokumoto Masanori, Tsuruya Kazuhiko, Kitazono Takanari, Sasaguri Toshiyuki
Physiological reports, Nov. 2016, Null, Null

薬物送達システム, 炎症・免疫異常の薬, 抗悪性腫瘍薬（抗がん薬）
笹栗俊之, 宮田篤郎, 有岡将基, 池松秀之, 上野晋, 江頭伸昭, 大池正宏, 栗原崇, 樗木晶子, 西昭徳, 吉原達也, Contributor
丸善書院, Mar. 2018