Extracellular vesicle microRNAs from human bone marrow MSCs suppress fibrogenesis of hepatic stellate cells by downregulation of RhoA signaling.
Daiki Kawamoto; Toshihiko Matsumoto; Tsuyoshi Fujioka; Shuhei Shinoda; Koichi Fujisawa; Tsuyoshi Ishikawa; Naoki Yamamoto; Taro Takami
Stem cells (Dayton, Ohio), Feb. 2026

エルゴチオネインの摂取が概日リズムの乱れで生じる酸化ストレスにおよぼす影響
藤原 広明; 李 云善; 藤澤 浩一; 河井 一明; 丸山 崇; 上田 陽一
日本病態生理学会雑誌, Aug. 2025

Formation of the toxic furan metabolite 2-butene-1,4-dial through hemin-induced degradation of 2,4-alkadienals in fried foods.
Hiroshi Kasai; Kazuaki Kawai; Koichi Fujisawa
Genes and environment : the official journal of the Japanese Environmental Mutagen Society, Apr. 2025

Effects of ergothioneine on oxidative DNA damage and immune response induced by circadian rhythm disturbance in mice.
Yun-Shan Li; Hiroaki Fujihara; Koichi Fujisawa; Kazuaki Kawai
Journal of clinical biochemistry and nutrition, Mar. 2025

Diurnal and daily fluctuations in levels of the urinary oxidative stress marker 8-hydroxyguanosine in spot urine samples.
Yun-Shan Li; Koichi Fujisawa; Kazuaki Kawai
Genes and environment : the official journal of the Japanese Environmental Mutagen Society, Jan. 2025

Effect of circadian rhythm disruption induced by time-restricted feeding and exercise on oxidative stress and immune in mice.
Yun-Shan Li; Hiroaki Fujihara; Koichi Fujisawa; Kazuaki Kawai
Journal of clinical biochemistry and nutrition, Jan. 2025

Varying impact of lenvatinib or sorafenib therapy on skeletal muscle loss in patients with hepatocellular carcinoma.
Yurika Yamauchi; Issei Saeki; Koichi Fujisawa; Maho Egusa; Natsuko Nishiyama; Tsuyoshi Fujioka; Daiki Kawamoto; Ryo Sasaki; Tatsuro Nishimura; Norikazu Tanabe; Takuro Hisanaga; Toshihiko Matsumoto; Tsuyoshi Ishikawa; Takahiro Yamasaki; Taro Takami
Oncology, Jan. 2024

Metabolic Analysis of DFO-Resistant Huh7 Cells and Identification of Targets for Combination Therapy.
Koichi Fujisawa; Toshihiko Matsumoto; Naoki Yamamoto; Takahiro Yamasaki; Taro Takami
Metabolites, Oct. 2023

Assessment of exposure and DNA damage from second-hand smoke using potential biomarker in urine: cigarettes and heated tobacco products.
Yuya Kawasaki; Yun-Shan Li; Yuko Ootsuyama; Koichi Fujisawa; Hisamitsu Omori; Ayumi Onoue; Kenichi Kubota; Toshimi Yoshino; Yoshio Nonami; Minoru Yoshida; Hiroshi Yamato; Kazuaki Kawai
Journal of clinical biochemistry and nutrition, May 2023

Regulation of Adenine Nucleotide Metabolism by Adenylate Kinase Isozymes: Physiological Roles and Diseases.
Koichi Fujisawa
International journal of molecular sciences, Mar. 2023

Optimizing the Seeding Density of Human Mononuclear Cells to Improve the Purity of Highly Proliferative Mesenchymal Stem Cells.
Hiroyuki Nagai; Akihiro Miwa; Kenji Yoneda; Koichi Fujisawa; Taro Takami
Bioengineering (Basel, Switzerland), Jan. 2023

MC180295 Inhibited Epstein-Barr Virus-Associated Gastric Carcinoma Cell Growth by Suppressing DNA Repair and the Cell Cycle.
Tomohiro Fujii; Jun Nishikawa; Soichiro Fukuda; Naoto Kubota; Junzo Nojima; Koichi Fujisawa; Ryo Ogawa; Atsushi Goto; Koichi Hamabe; Shinichi Hashimoto; Aung Phyo Wai; Hisashi Iizasa; Hironori Yoshiyama; Kohei Sakai; Yutaka Suehiro; Takahiro Yamasaki; Taro Takami
International journal of molecular sciences, Sep. 2022

Evaluation of the Effects of Microgravity on Activated Primary Human Hepatic Stellate Cells.
Koichi Fujisawa; Yuto Nishimura; Akino Sakuragi; Jolien Duponselle; Toshihiko Matsumoto; Naoki Yamamoto; Tomoaki Murata; Isao Sakaida; Taro Takami
International journal of molecular sciences, Jul. 2022

Involvement of DNA Damage Response via the Ccndbp1-Atm-Chk2 Pathway in Mice with Dextran-Sodium-Sulfate-Induced Colitis.
Ryoko Horigome; Kenya Kamimura; Yusuke Niwa; Kohei Ogawa; Ken-Ichi Mizuno; Koichi Fujisawa; Naoki Yamamoto; Taro Takami; Tomoyuki Sugano; Akira Sakamaki; Hiroteru Kamimura; Masaaki Takamura; Shuji Terai
Journal of clinical medicine, Jun. 2022

An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells.
Koichi Fujisawa; Taro Takami; Toshihiko Matsumoto; Naoki Yamamoto; Takahiro Yamasaki; Isao Sakaida
Cancer & metabolism, May 2022

Adenylate Kinase Isozyme 3 Regulates Mitochondrial Energy Metabolism and Knockout Alters HeLa Cell Metabolism.
Koichi Fujisawa; Maina Wakazaki; Aya Matsuzaki; Toshihiko Matsumoto; Naoki Yamamoto; Takafumi Noma; Taro Takami
International journal of molecular sciences, Apr. 2022

Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM-CHK2 Pathway.
Yusuke Niwa; Kenya Kamimura; Kohei Ogawa; Chiyumi Oda; Yuto Tanaka; Ryoko Horigome; Masato Ohtsuka; Hiromi Miura; Koichi Fujisawa; Naoki Yamamoto; Taro Takami; Shujiro Okuda; Masayoshi Ko; Takashi Owaki; Atsushi Kimura; Osamu Shibata; Shinichi Morita; Norihiro Sakai; Hiroyuki Abe; Takeshi Yokoo; Akira Sakamaki; Hiroteru Kamimura; Shuji Terai
Journal of clinical medicine, Feb. 2022

Establishment of an Adult Medaka Fatty Liver Model by Administration of a Gubra-Amylin-Nonalcoholic Steatohepatitis Diet Containing High Levels of Palmitic Acid and Fructose.
Koichi Fujisawa; Taro Takami; Shoki Okubo; Yuto Nishimura; Yusaku Yamada; Keisuke Kondo; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
International journal of molecular sciences, Sep. 2021

Seasonal variations in photoperiod affect hepatic metabolism of medaka (Oryzias latipes).
Koichi Fujisawa; Taro Takami; Haruko Shintani; Nanami Sasai; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
FEBS open bio, Jan. 2021

Mesenchymal Stem Cells Induce a Fibrolytic Phenotype By Regulating mmu-miR-6769b-5p Expression in Macrophages.
Maiko Nishi; Toshihiko Matsumoto; Koichi Fujisawa; Yutaka Suehiro; Taro Takami; Naoki Yamamoto; Takahiro Yamasaki; Isao Sakaida
Stem cells and development, Nov. 2020

Trans-portal hepatic infusion of cultured bone marrow-derived mesenchymal stem cells in a steatohepatitis murine model.
Ryo Sasaki; Taro Takami; Koichi Fujisawa; Toshihiko Matsumoto; Tsuyoshi Ishikawa; Naoki Yamamoto; Isao Sakaida
Journal of clinical biochemistry and nutrition, Nov. 2020

Dantrolene prevents hepatic steatosis by reducing cytoplasmic Ca2+ level and ER stress.
Masaki Tamitani; Takeshi Yamamoto; Naoki Yamamoto; Koichi Fujisawa; Shinji Tanaka; Yoshihide Nakamura; Hitoshi Uchinoumi; Tetsuro Oda; Shinichi Okuda; Taro Takami; Shigeki Kobayashi; Isao Sakaida; Masafumi Yano
Biochemistry and biophysics reports, Sep. 2020, Reviewed, No invitation

Metabolic Alterations in Spheroid-Cultured Hepatic Stellate Cells.
Koichi Fujisawa; Taro Takami; Nanami Sasai; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
International journal of molecular sciences, May 2020, Reviewed, No invitation

Bone marrow-derived humoral factors suppress oxidative phosphorylation, upregulate TSG-6, and improve therapeutic effects on liver injury of mesenchymal stem cells.
Takashi Miyaji; Taro Takami; Koichi Fujisawa; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
Journal of clinical biochemistry and nutrition, May 2020, Reviewed, No invitation

Usefulness of adult medaka fish as a model for the evaluation of alcoholic fatty liver.
Koichi Fujisawa; Taro Takami; Takahiro Nagatomo; Yumi Fukui; Hisashi Hoshida; Issei Saeki; Toshihiko Matsumoto; Isao Hidaka; Naoki Yamamoto; Isao Sakaida
Alcohol (Fayetteville, N.Y.), Jun. 2019, Reviewed, No invitation

NUPR1 acts as a pro-survival factor in human bone marrow-derived mesenchymal stem cells and is induced by the hypoxia mimetic reagent deferoxamine.
Kazuhito Matsunaga; Koichi Fujisawa; Taro Takami; Guzel Burganova; Nanami Sasai; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
Journal of clinical biochemistry and nutrition, May 2019, Reviewed, No invitation

Evaluation of the Effects of Cultured Bone Marrow Mesenchymal Stem Cell Infusion on Hepatocarcinogenesis in Hepatocarcinogenic Mice With Liver Cirrhosis.
Fujisawa Koichi
Transplantation proceedings, 2019, Reviewed, No invitation

Liver regeneration therapy through the hepatic artery-infusion of cultured bone marrow cells in a canine liver fibrosis model.
Tatsuro Nishimura; Taro Takami; Ryo Sasaki; Yuki Aibe; Takashi Matsuda; Koichi Fujisawa; Toshihiko Matsumoto; Naoki Yamamoto; Kenji Tani; Yasuho Taura; Isao Sakaida
PloS one, 2019, Reviewed, No invitation

Assessment of high-fat-diet-induced fatty liver in medaka.
Koichi Fujisawa; Taro Takami; Yumi Fukui; Takahiro Nagatomo; Issei Saeki; Toshihiko Matsumoto; Isao Hidaka; Naoki Yamamoto; Takeshi Okamoto; Makoto Furutani-Seiki; Isao Sakaida
Biology open, Nov. 2018, Reviewed, No invitation

Treatment strategies for advanced hepatocellular carcinoma: Sorafenib vs hepatic arterial infusion chemotherapy.
Issei Saeki; Takahiro Yamasaki; Masaki Maeda; Takuro Hisanaga; Takuya Iwamoto; Koichi Fujisawa; Toshihiko Matsumoto; Isao Hidaka; Yoshio Marumoto; Tsuyoshi Ishikawa; Naoki Yamamoto; Yutaka Suehiro; Taro Takami; Isao Sakaida
World journal of hepatology, Sep. 2018, Reviewed, No invitation

Analysis of Metabolomic Changes in Mesenchymal Stem Cells on Treatment with Desferrioxamine as a Hypoxia Mimetic Compared with Hypoxic Conditions.
Koichi Fujisawa; Taro Takami; Sae Okada; Kazusa Hara; Toshihiko Matsumoto; Naoki Yamamoto; Takahiro Yamasaki; Isao Sakaida
Stem cells (Dayton, Ohio), Aug. 2018, Reviewed, No invitation

Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil Differentiation.
Ayako Tanimura; Keiko Miyoshi; Taigo Horiguchi; Hiroko Hagita; Koichi Fujisawa; Takafumi Noma
Cellular Physiology and Biochemistry, Jul. 2018, Reviewed, No invitation

Deferasirox, an oral iron chelator, with gemcitabine synergistically inhibits pancreatic cancer cell growth in vitro and in vivo.
Shuhei Shinoda; Seiji Kaino; Shogo Amano; Hirofumi Harima; Toshihiko Matsumoto; Koichi Fujisawa; Taro Takami; Naoki Yamamoto; Takahiro Yamasaki; Isao Sakaida
Oncotarget, Jun. 2018, Reviewed, No invitation

Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells.
Koichi Fujisawa; Kazusa Hara; Taro Takami; Sae Okada; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
Stem cell research & therapy, Apr. 2018, Reviewed, No invitation

Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model
Yoko Shinagawa-Kobayashi; Kenya Kamimura; Ryo Goto; Kohei Ogawa; Ryosuke Inoue; Takeshi Yokoo; Norihiro Sakai; Takuro Nagoya; Akira Sakamaki; Satoshi Abe; Soichi Sugitani; Masahiko Yanagi; Koichi Fujisawa; Yoshizu Nozawa; Naoto Koyama; Hiroshi Nishina; Makoto Furutani-Seiki; Isao Sakaida; Shuji Terai
Biochemical and Biophysical Research Communications, Feb. 2018, Reviewed, No invitation

Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil Differentiation.
Tanimura A; Miyoshi K; Horiguchi T; Hagita H; Fujisawa K; Noma T
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Reviewed, No invitation

Profiling of the circadian metabolome in thioacetamide-induced liver cirrhosis in mice.
Koichi Fujisawa; Taro Takami; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
Hepatology communications, Sep. 2017, Reviewed, No invitation

Effectiveness of tolvaptan monotherapy and low-dose furosemide/tolvaptan combination therapy for hepatoprotection and diuresis in a rat cirrhotic model
Norikazu Tanabe; Taro Takami; Koichi Fujisawa; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, Jul. 2017, Reviewed, No invitation

Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver
Koichi Fujisawa; Taro Takami; Aya Matsuzaki; Toshihiko Matsumoto; Naoki Yamamoto; Shuji Terai; Isao Sakaida
SCIENTIFIC REPORTS, Jun. 2017, Reviewed, No invitation

Evaluating effects of L-carnitine on human bone-marrow-derived mesenchymal stem cells
Koichi Fujisawa; Taro Takami; Yumi Fukui; Luiz Fernando Quintanilha; Toshihiko Matsumoto; Naoki Yamamoto; Isao Sakaida
CELL AND TISSUE RESEARCH, May 2017, Reviewed, No invitation

Protective Effect of Daikenchuto on Dextran Sulfate Sodium-Induced Colitis in Mice
Takaharu Matsunaga; Shinichi Hashimoto; Naoki Yamamoto; Ryo Kawasato; Tomohiro Shirasawa; Atsushi Goto; Koichi Fujisawa; Taro Takami; Takeshi Okamoto; Jun Nishikawa; Isao Sakaida
GASTROENTEROLOGY RESEARCH AND PRACTICE, 2017, Reviewed, No invitation

Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma
Issei Saeki; Naoki Yamamoto; Takahiro Yamasaki; Taro Takami; Masaki Maeda; Koichi Fujisawa; Takuya Iwamoto; Toshihiko Matsumoto; Isao Hidaka; Tsuyoshi Ishikawa; Koichi Uchida; Kenji Tani; Isao Sakaida
WORLD JOURNAL OF GASTROENTEROLOGY, Oct. 2016, Reviewed, No invitation

Deferasirox, a novel oral iron chelator, shows antiproliferative activity against pancreatic cancer in vitro and in vivo
Hirofumi Harima; Seiji Kaino; Taro Takami; Shuhei Shinoda; Toshihiko Matsumoto; Koichi Fujisawa; Naoki Yamamoto; Takahiro Yamasaki; Isao Sakaida
BMC CANCER, Aug. 2016, Reviewed, No invitation

Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib
Naoki Yamamoto; Takahiro Yamasaki; Taro Takami; Koichi Uchida; Koichi Fujisawa; Toshihiko Matsumoto; Issei Saeki; Shuji Terai; Isao Sakaida
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, May 2016, Reviewed, No invitation

Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4
Koichi Fujisawa; Shuji Terai; Taro Takami; Naoki Yamamoto; Takahiro Yamasaki; Toshihiko Matsumoto; Kazuhito Yamaguchi; Yuji Owada; Hiroshi Nishina; Takafumi Noma; Isao Sakaida
Journal of Experimental and Clinical Cancer Research, Mar. 2016, Reviewed, No invitation

Circadian variations in the liver metabolites of medaka (Oryzias latipes)
Koichi Fujisawa; Taro Takami; Yoshitaka Kimoto; Toshihiko Matsumoto; Naoki Yamamoto; Shuji Terai; Isao Sakaida
SCIENTIFIC REPORTS, Feb. 2016, Reviewed, No invitation

Predictors of the Effect of Tolvaptan on the Prognosis of Cirrhosis
Takuya Iwamoto; Masaki Maeda; Takuro Hisanaga; Issei Saeki; Koichi Fujisawa; Toshihiko Matsumoto; Isao Hidaka; Tsuyoshi Ishikawa; Taro Takami; Isao Sakaida
INTERNAL MEDICINE, 2016, Reviewed, No invitation

Enhanced survival of mice infused with bone marrow-derived as compared with adipose-derived mesenchymal stem cells
Shogo Shiratsuki; Shuji Terai; Yasuhiko Murata; Taro Takami; Naoki Yamamoto; Koichi Fujisawa; Guzel Burganova; Luiz Fernando Quintanilha; Isao Sakaida
HEPATOLOGY RESEARCH, Dec. 2015, Reviewed, No invitation

Histological and Transcriptomic Analysis of Adult Japanese Medaka Sampled Onboard the International Space Station
Yasuhiko Murata; Takako Yasuda; Tomomi Watanabe-Asaka; Shoji Oda; Akiko Mantoku; Kazuhiro Takeyama; Masahiro Chatani; Akira Kudo; Satoko Uchida; Hiromi Suzuki; Fumiaki Tanigaki; Masaki Shirakawa; Koichi Fujisawa; Yoshihiko Hamamoto; Shuji Terai; Hiroshi Mitani
PLOS ONE, Oct. 2015, Reviewed, No invitation

Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging (vol 10, e0129950, 2015)
Koichi Fujisawa; Shuji Terai; Toshihiko Matsumoto; Taro Takami; Naoki Yamamoto; Hiroshi Nishina; Makoto Furutani-Seiki; Isao Sakaida
PLOS ONE, Aug. 2015, Reviewed, No invitation

Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging
Koichi Fujisawa; Shuji Terai; Toshihiko Matsumoto; Taro Takami; Naoki Yamamoto; Hiroshi Nishina; Makoto Furutani-Seiki; Isao Sakaida
PLOS ONE, Jun. 2015, Reviewed, No invitation

Canine mesenchymal stem cells show antioxidant properties against thioacetamide-induced liver injury in vitro and in vivo
Luiz Fernando Quintanilha; Taro Takami; Yoshikazu Hirose; Koichi Fujisawa; Yasuhiko Murata; Naoki Yamamoto; Regina Coeli dos Santos Goldenberg; Shuji Terai; Isao Sakaida
HEPATOLOGY RESEARCH, Oct. 2014, Reviewed, No invitation

Status and Prospects of Liver Cirrhosis Treatment by Using Bone Marrow-Derived Cells and Mesenchymal Cells
Shuji Terai; Taro Takami; Naoki Yamamoto; Koichi Fujisawa; Tsuyoshi Ishikawa; Yohei Urata; Haruko Tanimoto; Takuya Iwamoto; Yuko Mizunaga; Takashi Matsuda; Takashi Oono; Miho Marumoto; Guzel Burganova; Luiz Fernando Quintanilha; Isao Hidaka; Yoshio Marumoto; Issei Saeki; Koichi Uchida; Takahiro Yamasaki; Kenji Tani; Yasuho Taura; Yasuhiko Fujii; Hiroshi Nishina; Kiwamu Okita; Isao Sakaida
TISSUE ENGINEERING PART B-REVIEWS, Jun. 2014, Reviewed, No invitation

Status and Prospects of Liver Cirrhosis Treatment by Using Bone Marrow-Derived Cells and Mesenchymal Cells
Shuji Terai; Taro Takami; Naoki Yamamoto; Koichi Fujisawa; Tsuyoshi Ishikawa; Yohei Urata; Haruko Tanimoto; Takuya Iwamoto; Yuko Mizunaga; Takashi Matsuda; Takashi Oono; Miho Marumoto; Guzel Burganova; Luiz Fernando Quintanilha; Isao Hidaka; Yoshio Marumoto; Issei Saeki; Koichi Uchida; Takahiro Yamasaki; Kenji Tani; Yasuho Taura; Yasuhiko Fujii; Hiroshi Nishina; Kiwamu Okita; Isao Sakaida
TISSUE ENGINEERING PART B-REVIEWS, Jun. 2014, Reviewed, No invitation

Adenylate kinase 2 deficiency limits survival and regulates various genes during larval stages of Drosophila melanogaster
Taigo Horiguchi; Miyuki Fuka; Koichi Fujisawa; Ayako Tanimura; Keiko Miyoshi; Ryutaro Murakami; Takafumi Noma
Journal of Medical Investigation, 2014, Reviewed, No invitation

Improvement of liver fibrosis by infusion of cultured cells derived from human bone marrow
Haruko Tanimoto; Shuji Terai; Takami Taro; Yasuhiko Murata; Kouichi Fujisawa; Naoki Yamamoto; Isao Sakaida
CELL AND TISSUE RESEARCH, Dec. 2013, Reviewed, No invitation

Bortezomib induces tumor-specific cell death and growth inhibition in hepatocellular carcinoma and improves liver fibrosis
Issei Saeki; Shuji Terai; Koichi Fujisawa; Taro Takami; Naoki Yamamoto; Toshihiko Matsumoto; Yoshikazu Hirose; Yasuhiko Murata; Takahiro Yamasaki; Isao Sakaida
Journal of Gastroenterology, Jun. 2013, Reviewed, No invitation

Timeline for development of autologous bone marrow infusion (ABMi) therapy and perspective for future stem cell therapy
Shuji Terai; Haruko Tanimoto; Masaki Maeda; Junichi Zaitsu; Takuro Hisanaga; Takuya Iwamoto; Koichi Fujisawa; Yuko Mizunaga; Toshihiko Matsumoto; Yohei Urata; Yoshio Marumoto; Isao Hidaka; Tsuyoshi Ishikawa; Yuichiro Yokoyama; Koji Aoyama; Masako Tsuchiya; Taro Takami; Kaoru Omori; Naoki Yamamoto; Makoto Segawa; Koichi Uchida; Takahiro Yamasaki; Kiwamu Okita; Isao Sakaida
JOURNAL OF GASTROENTEROLOGY, May 2012, Reviewed, No invitation

Ezetimibe reduces fatty acid quantity in liver and decreased inflammatory cell infiltration and improved NASH in medaka model
Toshiyuki Oishi; Shuji Terai; Shinya Kuwashiro; Koichi Fujisawa; Toshihiko Matsumoto; Hiroshi Nishina; Isao Sakaida
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2012, Reviewed, No invitation

Senescence marker protein 30 (SMP30)/regucalcin (RGN) expression decreases with aging, acute liver injuries and tumors in zebrafish
Koichi Fujisawa; Shuji Terai; Yoshikazu Hirose; Taro Takami; Naoki Yamamoto; Isao Sakaida
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Oct. 2011, Reviewed, No invitation

Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation
Shinya Kuwashiro; Shuji Terai; Toshiyuki Oishi; Koichi Fujisawa; Toshihiko Matsumoto; Hiroshi Nishina; Isao Sakaida
CELL AND TISSUE RESEARCH, Apr. 2011, Reviewed, No invitation

Xyloglucan endotransglycosylase/hydrolase genes in cotton and their role in fiber elongation
Joohyun Lee; Teresa H. Burns; Ginger Light; Yan Sun; Mohamed Fokar; Yoshihisha Kasukabe; Koichi Fujisawa; Yoshihiko Maekawa; Randy D. Allen
PLANTA, Oct. 2010, Reviewed, No invitation

Medaka as a model for human nonalcoholic steatohepatitis
Toshihiko Matsumoto; Shuji Terai; Toshiyuki Oishi; Shinya Kuwashiro; Koichi Fujisawa; Naoki Yamamoto; Yusuke Fujita; Yoshihiko Hamamoto; Makoto Furutani-Seiki; Hiroshi Nishina; Isao Sakaida
DISEASE MODELS & MECHANISMS, Jul. 2010, Reviewed, No invitation

Adenylate kinase isozyme 2 is essential for growth and development of Drosophila melanogaster
Koichi Fujisawa; Ryutaro Murakami; Taigo Horiguchi; Takafumi Noma
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, May 2009, Reviewed, No invitation

Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver
Yoshio Marumoto; Shuji Tera; Yohei Urata; Toshihiko Matsumoto; Yuko Mizunaga; Naoki Yamamoto; Haiyan Jina; Koichi Fujisawa; Tomoaki Murata; Koh Shinoda; Hiroshi Nishina; Isao Sakaida
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Mar. 2008, Reviewed, No invitation

The development of new drug screening system using steatohepatitis medaka fish model induced by high-fat diet
Matsumoto Toshihiko; Terai Shuji; Kuwashiro Shinya; Fujisawa Koichi; Yamamoto Naoki; Hamamoto Yoshihiko; Sakaida Isao
HEPATOLOGY, Oct. 2007, Reviewed, No invitation

Structure and expression of human mitochondrial adenylate kinase targeted to the mitochondrial matrix
T Noma; K Fujisawa; Y Yamashiro; M Shinohara; A Nakazawa; T Gondo; T Ishihara; K Yoshinobu
BIOCHEMICAL JOURNAL, Aug. 2001, Reviewed, No invitation

cDNA cloning and chromosomal mapping of the gene encoding adenylate kinase 2 from Drosophila melanogaster.
Noma T; Murakami R; Yamashiro Y; Fujisawa K; Inouye S; Nakazawa A
Biochimica et biophysica acta, Jan. 2000, Reviewed, No invitation

Regulation of NeuroD expression by activation of the protein kinase-C pathway in Y79 human retinoblastoma cells
T Noma; YS Yoon; Y Yamashiro; K Fujisawa; A Nakazawa
NEUROSCIENCE LETTERS, Sep. 1999, Reviewed, No invitation

REGULATION OF ASCORBATE OXIDASE EXPRESSION IN PUMPKIN BY AUXIN AND COPPER
M ESAKA; K FUJISAWA; M GOTO; Y KISU
PLANT PHYSIOLOGY, Sep. 1992, Reviewed, No invitation

MOLECULAR-CLONING AND NUCLEOTIDE-SEQUENCE OF FULL-LENGTH CDNA FOR ASCORBATE OXIDASE FROM CULTURED PUMPKIN CELLS
M ESAKA; T HATTORI; K FUJISAWA; S SAKAJO; T ASAHI
EUROPEAN JOURNAL OF BIOCHEMISTRY, Aug. 1990, Reviewed, No invitation

Optimizing the Seeding Density of Human Mononuclear Cells to Improve the Purity of Highly Proliferative Mesenchymal Stem Cells.
Nagai Hiroyuki, Miwa Akihiro, Yoneda Kenji, Fujisawa Koichi, Takami Taro
Bioengineering (Basel, Switzerland), Jan. 2023, Reviewed, No invitation

An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells.
Fujisawa Koichi, Takami Taro, Matsumoto Toshihiko, Yamamoto Naoki, Yamasaki Takahiro, Sakaida Isao
Cancer & metabolism, May 2022, Reviewed, No invitation
Lead

Regulation of Adenine Nucleotide Metabolism by Adenylate Kinase Isozymes: Physiological Roles and Diseases.
Fujisawa Koichi
International journal of molecular sciences, Mar. 2023, Reviewed, No invitation
Lead

Adenylate Kinase Isozyme 3 Regulates Mitochondrial Energy Metabolism and Knockout Alters HeLa Cell Metabolism.
Fujisawa Koichi, Wakazaki Maina, Matsuzaki Aya, Matsumoto Toshihiko, Yamamoto Naoki, Noma Takafumi, Takami Taro
International journal of molecular sciences, Apr. 2022, Reviewed, No invitation
Lead

MC180295 Inhibited Epstein-Barr Virus-Associated Gastric Carcinoma Cell Growth by Suppressing DNA Repair and the Cell Cycle.
Fujii Tomohiro, Nishikawa Jun, Fukuda Soichiro, Kubota Naoto, Nojima Junzo, Fujisawa Koichi, Ogawa Ryo, Goto Atsushi, Hamabe Koichi, Hashimoto Shinichi, Wai Aung Phyo, Iizasa Hisashi, Yoshiyama Hironori, Sakai Kohei, Suehiro Yutaka, Yamasaki Takahiro, Takami Taro
International journal of molecular sciences, Sep. 2022, Reviewed, No invitation

Evaluation of the Effects of Microgravity on Activated Primary Human Hepatic Stellate Cells.
Fujisawa Koichi, Nishimura Yuto, Sakuragi Akino, Duponselle Jolien, Matsumoto Toshihiko, Yamamoto Naoki, Murata Tomoaki, Sakaida Isao, Takami Taro
International journal of molecular sciences, Jul. 2022, Reviewed, No invitation
Lead

Assessment of exposure and DNA damage from second-hand smoke using potential biomarker in urine: cigarettes and heated tobacco products
Yuya Kawasaki, Yun-Shan Li, Yuko Ootsuyama, Koichi Fujisawa, Hisamitsu Omori, Ayumi Onoue, Kenichi Kubota, Toshimi Yoshino, Yoshio Nonami, Minoru Yoshida, Hiroshi Yamato, and Kawai Kazuaki
Journal of Clinical Biochemistry and Nutrition, May 2023, Reviewed, Null

Involvement of DNA Damage Response via the Ccndbp1-Atm-Chk2 Pathway in Mice with Dextran-Sodium-Sulfate-Induced Colitis.
Horigome Ryoko, Kamimura Kenya, Niwa Yusuke, Ogawa Kohei, Mizuno Ken-Ichi, Fujisawa Koichi, Yamamoto Naoki, Takami Taro, Sugano Tomoyuki, Sakamaki Akira, Kamimura Hiroteru, Takamura Masaaki, Terai Shuji
Journal of clinical medicine, Jun. 2022, Reviewed, No invitation

Metabolic Analysis of DFO-Resistant Huh7 Cells and Identification of Targets for Combination Therapy.
Fujisawa Koichi, Matsumoto Toshihiko, Yamamoto Naoki, Yamasaki Takahiro, Takami Taro
Metabolites, Oct. 2023, Reviewed, No invitation
Lead, Corresponding

Varying impact of lenvatinib or sorafenib therapy on skeletal muscle loss in patients with hepatocellular carcinoma.
Yamauchi Yurika, Saeki Issei, Fujisawa Koichi, Egusa Maho, Nishiyama Natsuko, Fujioka Tsuyoshi, Kawamoto Daiki, Sasaki Ryo, Nishimura Tatsuro, Tanabe Norikazu, Hisanaga Takuro, Matsumoto Toshihiko, Ishikawa Tsuyoshi, Yamasaki Takahiro, Takami Taro
Oncology, Jan. 2024, Reviewed, Null

Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM-CHK2 Pathway.
Niwa Yusuke, Kamimura Kenya, Ogawa Kohei, Oda Chiyumi, Tanaka Yuto, Horigome Ryoko, Ohtsuka Masato, Miura Hiromi, Fujisawa Koichi, Yamamoto Naoki, Takami Taro, Okuda Shujiro, Ko Masayoshi, Owaki Takashi, Kimura Atsushi, Shibata Osamu, Morita Shinichi, Sakai Norihiro, Abe Hiroyuki, Yokoo Takeshi, Sakamaki Akira, Kamimura Hiroteru, Terai Shuji
Journal of clinical medicine, Feb. 2022, Null, Null