Feb. 2023
研究奨励賞
第25回日本亜鉛栄養治療研究会
Emi Yoshigai

Zinc in Biology: Molecular Structures, Cellular Processes and Living Systems.
Takafumi Hara; Emi Yoshigai; Toshiyuki Fukada
Royal Society of Chemistry., Jul. 2025, Reviewed

Possible involvement of zinc transporter ZIP13 in myogenic differentiation.
Masaki Shoji; Takuto Ohashi; Saki Nagase; Haato Yuri; Kenta Ichihashi; Teruhisa Takagishi; Yuji Nagata; Yuki Nomura; Ayako Fukunaka; Sae Kenjou; Hatsuna Miyake; Takafumi Hara; Emi Yoshigai; Yoshio Fujitani; Hidetoshi Sakurai; Heloísa G Dos Santos; Toshiyuki Fukada; Takashi Kuzuhara
Scientific reports, Apr. 2024, Reviewed

Zinc in Cardiovascular Functions and Diseases: Epidemiology and Molecular Mechanisms for Therapeutic Development.
Takafumi Hara; Emi Yoshigai; Takuto Ohashi; Toshiyuki Fukada
International journal of molecular sciences, Apr. 2023, Reviewed

Zinc transporters as potential therapeutic targets: An updated review.
Takafumi Hara; Emi Yoshigai; Takuto Ohashi; Toshiyuki Fukada
Journal of pharmacological sciences, Feb. 2022, Reviewed

Role of Scl39a13/ZIP13 in cardiovascular homeostasis.
Takafumi Hara; Ikuko Yamada; Takuto Ohashi; Masaru Tamura; Atsushi Hijikata; Takashi Watanabe; Minghao Gao; Kana Ito; Saeko Kawamata; Shiori Azuma; Emi Yoshigai; Yukiko Sumiyoshi; Natsumi Yasuhiro; Osamu Ohara; Heloísa G Dos Santos; Toshiyuki Fukada
PloS one, 2022, Reviewed

Implication of the zinc-epigenetic axis in epidermal homeostasis.
Mi-Gi Lee; Sehyun Chae; Kimiko Nakajima; Miho Ibi; Hozumi Sano; Takafumi Hara; Hantae Jo; Teruhisa Takagishi; Byungsun Cha; Jin-Myoung Baek; Emi Yoshigai; Takuto Ohashi; Tarou Irié; Shigetoshi Sano; Jong-Soo Lee; Toshiyuki Fukada; Bum-Ho Bin
Journal of dermatological science, Jun. 2020, Reviewed

Zinc transporters in physiology and pathophysiology
Toshiyuki Fukada; Takafumi Hara; Teruhisa Takagishi; Emi Yoshigai; Xin Lian; Bum Ho Bin
Essential and Toxic Trace Elements and Vitamins in Human Health, Jan. 2020, Reviewed

Spatiotemporal expression of Prdm genes during Xenopus development.
Rieko Eguchi; Emi Yoshigai; Takamasa Koga; Satoru Kuhara; Kosuke Tashiro
Cytotechnology, Aug. 2015, Reviewed

Antipyretic analgesic drugs have different mechanisms for regulation of the expression of inducible nitric oxide synthase in hepatocytes and macrophages.
Inaba H; Yoshigai E; Okuyama T; Murakoshi M; Sugiyama K; Nishino H; Nishizawa M
Nitric Oxide, Jan. 2015, Reviewed, No invitation

A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes.
Nakajima A; Yamamoto Y; Yoshinaka N; Namba M; Matsuo H; Okuyama T; Yoshigai E; Okumura T; Nishizawa M; Ikeya Y
Bioscience, biotechnology, and biochemistry, 2015, Reviewed, No invitation

Temporal and spatial dependence of inflammatory biomarkers and suppression by fluvastatin in dextran sodium sulfate-induced rat colitis model.
Masaharu Oishi; Katsuji Tokuhara; Hirokazu Miki; Yoshito Tanaka; So Yamaki; Masaki Kaibori; Katsuhiko Yoshizawa; Takashi Yuri; Emi Yoshigai; Mikio Nishizawa; Tadayoshi Okumura; A-Hon Kwon
Digestive diseases and sciences, Sep. 2014, Reviewed

The Anti-Inflammatory Effects of Flavanol-Rich Lychee Fruit Extract in Rat Hepatocytes
Ryota Yamanishi; Emi Yoshigai; Tetsuya Okuyama; Masatoshi Mori; Hiromitsu Murase; Toru Machida; Tadayoshi Okumura; Mikio Nishizawa
PLOS ONE, Apr. 2014, Reviewed, No invitation

Interleukin-1β induces tumor necrosis factor-α secretion from rat hepatocytes
Emi Yoshigai; Takafumi Hara; Hiroyuki Inaba; Iwao Hashimoto; Yoshito Tanaka; Masaki Kaibori; Tominori Kimura; Tadayoshi Okumura; A-Hon Kwon; Mikio Nishizawa
Hepatology Research, 2014, Reviewed, No invitation
Lead

Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1beta-treated hepatocytes
Emi Yoshigai; Toru Machida; Tetsuya Okuyama; Masatoshi Mori; Hiromitsu Murase; Ryota Yamanishi; Tadayoshi Okumura; Yukinobu Ikeya; Hoyoku Nishino; Mikio Nishizawa
Biochemical and Biophysical Research Communications, Sep. 2013, Reviewed, No invitation
Lead

Active Hexose Correlated Compound Extends the Lifespan and Increases the Thermotolerance of Nematodes
Tetsuya Okuyama; Emi Yoshigai; Yukinobu Ikeya; Mikio Nishizawa
Functional Foods in Health and Disease, Jun. 2013, Reviewed, No invitation

Stabilization of human interferon-alpha 1 mRNA by its antisense RNA
Tominori Kimura; Shiwen Jiang; Mikio Nishizawa; Emi Yoshigai; Iwao Hashimoto; Masao Nishikawa; Tadayoshi Okumura; Hisao Yamada
CELLULAR AND MOLECULAR LIFE SCIENCES, Apr. 2013, Reviewed, No invitation

Natural antisense transcript-targeted regulation of inducible nitric oxide synthase mRNA levels
Emi Yoshigai; Takafumi Hara; Yoshiro Araki; Yoshito Tanaka; Masaharu Oishi; Katsuji Tokuhara; Masaki Kaibori; Tadayoshi Okumura; A-Hon Kwon; Mikio Nishizawa
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, Apr. 2013, Reviewed, No invitation
Lead

Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPβ and NF-κB in rat hepatocytes
Yuna Takimoto; Hai-Yan Qian; Emi Yoshigai; Tadayoshi Okumura; Yukinobu Ikeya; Mikio Nishizawa
Nitric Oxide - Biology and Chemistry, Jan. 2013, Reviewed, No invitation

Characterization of natural antisense transcripts expressed from interleukin 1β-inducible genes in rat hepatocytes
Yoshigai E; Hara T; Okuyama T; Okumura T; Kaibori M; Kwon AH; Nishizawa M
HOAJ Biology, Sep. 2012, Not reviewed, No invitation

Chlorogenic acid is responsible for anti-inflammatory effects of the Japanese herbal drug Kinginka (Flos Lonicerae japonicae)
Yoshigai E; Ohno N; Okuyama T; Yamamoto Y; Okumura T; Sato K; Ikey Y; Nishizawa M
Clinical Nutrition Supplements, Sep. 2012, Not reviewed, No invitation

Chlorogenic acid from the Japanese herbal medicine Kinginka (Flos Lonicerae japonicae) suppresses the expression of inducible nitric oxide synthase in rat hepatocytes
Ohno N; Yoshigai E; Okuyama T; Yamamoto Y; Okumura T; Sato K; Ikeya Y; Nishizawa M
HOAJ Biology, Apr. 2012, Not reviewed, No invitation

Supplementation with a Flavanol-rich Lychee Fruit Extract Influences the Inflammatory Status of Young Athletes
Mikio Nishizawa; Takafumi Hara; Takehito Miura; Satoshi Fujita; Emi Yoshigai; Hidetoshi Ue; Yukako Hayashi; A-Hon Kwon; Tadayoshi Okumura; Tadao Isaka
PHYTOTHERAPY RESEARCH, Oct. 2011, Reviewed, No invitation

Perilla leaf extract suppresses inducible nitric oxide synthase and anti-inflammatory cytokines in hepatocytes.
Yoshigai E; Miura T; Okumura T; Ikeya Y; Nishizawa M
Clinical Nutrition Supplemensts, Sep. 2010, Not reviewed, No invitation

Trim36/Haprin plays a critical role in the arrangement of somites during Xenopus embryogenesis
Emi Yoshigai; Shinobu Kawamura; Satoru Kuhara; Kosuke Tashiro
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jan. 2009, Reviewed, No invitation
Lead

smyd1 and smyd2 are expressed in muscle tissue in Xenopus laevis
Shinobu Kawamura; Emi Yoshigai; Satoru Kuhara; Kosuke Tashiro
CYTOTECHNOLOGY, Jun. 2008, Reviewed, No invitation

Zinc in Biology: Molecular Structures, Cellular Processes and Living Systems. Chapter 14: Zinc Transporters and Zinc Signaling in Disease Pathogenesis.
Hara T.; Yoshigai E.; Fukada T.
Royal Society of Chemistry., Jul. 2025
9781837674565

【微量元素みいつけた 生理作用・疾患・くすりと食品にクローズアップ!】ヒトのからだに微量元素が必要なワケ 金属タンパク質と金属酵素
原 貴史; 吉開 会美; 深田 俊幸
(株)南山堂, Mar. 2024
9784525940027

【微量元素とMgの最新知見を臨床に活かす!-機能・代謝・疾患との関連】亜鉛の最新知見 亜鉛トランスポーターの生理機能 個体恒常性の維持と亜鉛シグナル
吉開 会美; 原 貴史; 大橋 拓人; 深田 俊幸
医歯薬出版(株), Aug. 2022

生命金属ダイナミクス : 生体内における金属の挙動と制御, 第3節 亜鉛トランスポーター遺伝子改変マウスと疾患
原貴史, 吉開会美, 大橋拓人, 深田俊幸
エヌ・ティー・エス, Jan. 2021
9784860437060

【必須微量ミネラルの栄養学～亜鉛欠乏を中心に～】亜鉛トランスポーターの生理機能 個体恒常性の維持と亜鉛シグナル
原 貴史; 高岸 照久; 吉開 会美; 深田 俊幸
(株)ニュー・サイエンス社, Mar. 2020

元素シグナル 亜鉛シグナルによる生体恒常性の維持と疾患とのかかわり
高岸 照久; 原 貴史; 吉開 会美; 廉 馨; 深田 俊幸
(有)科学評論社, Feb. 2020

Essential and Toxic Trace Elements and Vitamins in Human Health, 1st Edition, Chapter 3-Zinc transporters in physiology and pathophysiology.
Fukada T.; Bin BH; Hara T.; Takagishi T.; Yoshigai E.; Xin Lian
2020

【トランスポーターのすべて】トランスポーターが関連する疾患研究 トランスポーターから究明する亜鉛恒常性システムの重要性
原 貴史; 高岸 照久; 吉開 会美; 深田 俊幸
医歯薬出版(株), Oct. 2019